Complex Systems Science in Biomedicine

Download Complex Systems Science in Biomedicine PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387335323
Total Pages : 857 pages
Book Rating : 4.3/5 (873 download)

DOWNLOAD NOW!


Book Synopsis Complex Systems Science in Biomedicine by : Thomas Deisboeck

Download or read book Complex Systems Science in Biomedicine written by Thomas Deisboeck and published by Springer Science & Business Media. This book was released on 2007-06-13 with total page 857 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complex Systems Science in Biomedicine Thomas S. Deisboeck and J. Yasha Kresh Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts. In Parts I & II, Complex Systems Science in Biomedicine provides a general systems thinking perspective and presents some of the fundamental theoretical underpinnings of this rapidly emerging field. Part III then follows with a multi-scaled approach, spanning from the molecular to macroscopic level, exemplified by studying such diverse areas as molecular networks and developmental processes, the immune and nervous systems, the heart, cancer and multi-organ failure. The volume concludes with Part IV that addresses methods and techniques driven in design and development by this new understanding of biomedical science. Key Topics Include: • Historic Perspectives of General Systems Thinking • Fundamental Methods and Techniques for Studying Complex Dynamical Systems • Applications from Molecular Networks to Disease Processes • Enabling Technologies for Exploration of Systems in the Life Sciences Complex Systems Science in Biomedicine is essential reading for experimental, theoretical, and interdisciplinary scientists working in the biomedical research field interested in a comprehensive overview of this rapidly emerging field. About the Editors: Thomas S. Deisboeck is currently Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School in Boston. An expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director of the Complex Biosystems Modeling Laboratory which is part of the Harvard-MIT Martinos Center for Biomedical Imaging. J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and Research Director, Professor of Medicine and Director of Cardiovascular Biophysics at the Drexel University College of Medicine. An expert in dynamical systems, he holds appointments in the School of Biomedical Engineering and Health Systems, Dept. of Mechanical Engineering and Molecular Pathobiology Program. Prof. Kresh is Fellow of the American College of Cardiology, American Heart Association, Biomedical Engineering Society, American Institute for Medical and Biological Engineering.

Complex Systems Science in Biomedicine

Download Complex Systems Science in Biomedicine PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 9780387510767
Total Pages : 864 pages
Book Rating : 4.5/5 (17 download)

DOWNLOAD NOW!


Book Synopsis Complex Systems Science in Biomedicine by : Thomas Deisboeck

Download or read book Complex Systems Science in Biomedicine written by Thomas Deisboeck and published by Springer. This book was released on 2010-11-16 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complex Systems Science in Biomedicine Thomas S. Deisboeck and J. Yasha Kresh Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts. In Parts I & II, Complex Systems Science in Biomedicine provides a general systems thinking perspective and presents some of the fundamental theoretical underpinnings of this rapidly emerging field. Part III then follows with a multi-scaled approach, spanning from the molecular to macroscopic level, exemplified by studying such diverse areas as molecular networks and developmental processes, the immune and nervous systems, the heart, cancer and multi-organ failure. The volume concludes with Part IV that addresses methods and techniques driven in design and development by this new understanding of biomedical science. Key Topics Include: • Historic Perspectives of General Systems Thinking • Fundamental Methods and Techniques for Studying Complex Dynamical Systems • Applications from Molecular Networks to Disease Processes • Enabling Technologies for Exploration of Systems in the Life Sciences Complex Systems Science in Biomedicine is essential reading for experimental, theoretical, and interdisciplinary scientists working in the biomedical research field interested in a comprehensive overview of this rapidly emerging field. About the Editors: Thomas S. Deisboeck is currently Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School in Boston. An expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director of the Complex Biosystems Modeling Laboratory which is part of the Harvard-MIT Martinos Center for Biomedical Imaging. J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and Research Director, Professor of Medicine and Director of Cardiovascular Biophysics at the Drexel University College of Medicine. An expert in dynamical systems, he holds appointments in the School of Biomedical Engineering and Health Systems, Dept. of Mechanical Engineering and Molecular Pathobiology Program. Prof. Kresh is Fellow of the American College of Cardiology, American Heart Association, Biomedical Engineering Society, American Institute for Medical and Biological Engineering.

Complex Systems in Medicine

Download Complex Systems in Medicine PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030245934
Total Pages : 255 pages
Book Rating : 4.0/5 (32 download)

DOWNLOAD NOW!


Book Synopsis Complex Systems in Medicine by : David C. Aron

Download or read book Complex Systems in Medicine written by David C. Aron and published by Springer Nature. This book was released on 2019-08-30 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique title explores complex systems in clinical medicine and the subsequent implementation of that knowledge into practice. Written conversationally and as a reflection on the journey of learning about complex systems, the book explores how knowledge of these systems can be applied to four key roles in academic medicine: clinical practice, education, research, and administration. Further, this title emphasizes how gaining an understanding of complex systems can greatly help a physician deal with the many challenges found in academic medicine. Unlike other books on complexity in medicine, which tend to focus on only one aspect of the management of patients, Complex Systems in Medicine deals with the multifaceted roles of a physician. The approach in this book is uniquely qualitative rather than mathematical, and is written to make it not only of interest to physicians, trainees, and allied health providers, but also to make it more accessible to a non-medical audience. The inclusion of personal anecdotes by the author provides concrete examples of the application of knowledge of complex systems in academic medicine. A first-of-its-kind contribution to the literature, Complex Systems in Medicine: A Hedgehog’s Tale of Complexity in Clinical Practice, Research, Education, and Management is not only a novel reference for medical professionals, it is an accessible tool for the non-medical audience hoping to learn more about complex systems and their direct relevance to medicine, a field that deals with the infinite variety of humans and their ills. It illustrates the consequences of the interactive elements of patient care that make medicine both a science and an art.

Introduction to Complexity and Complex Systems

Download Introduction to Complexity and Complex Systems PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 1439894981
Total Pages : 551 pages
Book Rating : 4.4/5 (398 download)

DOWNLOAD NOW!


Book Synopsis Introduction to Complexity and Complex Systems by : Robert B. Northrop

Download or read book Introduction to Complexity and Complex Systems written by Robert B. Northrop and published by CRC Press. This book was released on 2010-12-10 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: The boundaries between simple and complicated, and complicated and complex system designations are fuzzy and debatable, even using quantitative measures of complexity. However, if you are a biomedical engineer, a biologist, physiologist, economist, politician, stock market speculator, or politician, you have encountered complex systems. Furthermore, your success depends on your ability to successfully interact with and manage a variety of complex systems. In order not to be blindsided by unexpected results, we need a systematic, comprehensive way of analyzing, modeling, and simulating complex systems to predict non-anticipated outcomes. In its engaging first chapters, the book introduces complex systems, Campbell's Law, and the Law of Unintended Consequences, and mathematics necessary for conversations in complex systems. Subsequent chapters illustrate concepts via commonly studied biological mechanisms. The final chapters focus on higher-level complexity problems, and introduce complexity in economic systems. Designed as a reference for biologists and biological engineers, Introduction to Complexity and Complex Systems lends itself to use in a classroom course to introduce advanced students studying biomedical engineering, biophysics, or physiology to complex systems. Engaging and illustrative, this book aids scientists and decision makers in managing biological complexity and complex systems.

Systems Biomedicine

Download Systems Biomedicine PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0080919839
Total Pages : 450 pages
Book Rating : 4.0/5 (89 download)

DOWNLOAD NOW!


Book Synopsis Systems Biomedicine by : Edison T. Liu

Download or read book Systems Biomedicine written by Edison T. Liu and published by Academic Press. This book was released on 2009-09-17 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems biology is a critical emerging field that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to predict outcomes from component input. Applications in medicine are revolutionizing our understanding of biological processes and systems. Systems Biomedicine is organized around foundations, computational modeling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. An integrative approach to the underlying genomic, proteomic, and computational biology principles provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon. Organized to reflect the important distinguishing characteristics of systems strategies in experimental biology and medicine Provides precise and comprehensive measurement tools for constructing a model of the system and tools for defining complexity as an experimental dependent variable Includes a thorough discussion of the applications of quantitative principles to biomedical problems

Handbook of Systems and Complexity in Health

Download Handbook of Systems and Complexity in Health PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461449987
Total Pages : 941 pages
Book Rating : 4.4/5 (614 download)

DOWNLOAD NOW!


Book Synopsis Handbook of Systems and Complexity in Health by : Joachim P Sturmberg

Download or read book Handbook of Systems and Complexity in Health written by Joachim P Sturmberg and published by Springer Science & Business Media. This book was released on 2013-01-09 with total page 941 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an introduction to health care as a complex adaptive system, a system that feeds back on itself. The first section introduces systems and complexity theory from a science, historical, epistemological, and technical perspective, describing the principles and mathematics. Subsequent sections build on the health applications of systems science theory, from human physiology to medical decision making, population health and health services research. The aim of the book is to introduce and expand on important population health issues from a systems and complexity perspective, highlight current research developments and their implications for health care delivery, consider their ethical implications, and to suggest directions for and potential pitfalls in the future.

Complex Systems

Download Complex Systems PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309177502
Total Pages : 123 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Complex Systems by : National Academies

Download or read book Complex Systems written by National Academies and published by National Academies Press. This book was released on 2009-04-07 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Academies Keck Futures Initiative was launched in 2003 to stimulate new modes of scientific inquiry and break down the conceptual and institutional barriers to interdisciplinary research. At the Conference on Complex Systems, participants were divided into twelve interdisciplinary working groups. The groups spent nine hours over two days exploring diverse challenges at the interface of science, engineering, and medicine. The groups included researchers from science, engineering, and medicine, as well as representatives from private and public funding agencies, universities, businesses, journals, and the science media. The groups needed to address the challenge of communicating and working together from a diversity of expertise and perspectives as they attempted to solve complicated, interdisciplinary problems in a relatively short time. The summaries contained in this volume describe the problem and outline the approach taken, including what research needs to be done to understand the fundamental science behind the challenge, the proposed plan for engineering the application, the reasoning that went into it and the benefits to society of the problem solution.

Complex Systems in Medicine

Download Complex Systems in Medicine PDF Online Free

Author :
Publisher :
ISBN 13 : 9783030245948
Total Pages : 253 pages
Book Rating : 4.2/5 (459 download)

DOWNLOAD NOW!


Book Synopsis Complex Systems in Medicine by : David C. Aron

Download or read book Complex Systems in Medicine written by David C. Aron and published by . This book was released on 2020 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique title explores complex systems in clinical medicine and the subsequent implementation of that knowledge into practice. Written conversationally and as a reflection on the journey of learning about complex systems, the book explores how knowledge of these systems can be applied to four key roles in academic medicine: clinical practice, education, research, and administration. Further, this title emphasizes how gaining an understanding of complex systems can greatly help a physician deal with the many challenges found in academic medicine. Unlike other books on complexity in medicine, which tend to focus on only one aspect of the management of patients, Complex Systems in Medicine deals with the multifaceted roles of a physician. The approach in this book is uniquely qualitative rather than mathematical, and is written to make it not only of interest to physicians, trainees, and allied health providers, but also to make it more accessible to a non-medical audience. The inclusion of personal anecdotes by the author provides concrete examples of the application of knowledge of complex systems in academic medicine. A first-of-its-kind contribution to the literature, Complex Systems in Medicine: A Hedgehog's Tale of Complexity in Clinical Practice, Research, Education, and Management is not only a novel reference for medical professionals, it is an accessible tool for the non-medical audience hoping to learn more about complex systems and their direct relevance to medicine, a field that deals with the infinite variety of humans and their ills. It illustrates the consequences of the interactive elements of patient care that make medicine both a science and an art.

Complex Systems in Biomedicine

Download Complex Systems in Biomedicine PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 8847003962
Total Pages : 299 pages
Book Rating : 4.8/5 (47 download)

DOWNLOAD NOW!


Book Synopsis Complex Systems in Biomedicine by : A. Quarteroni

Download or read book Complex Systems in Biomedicine written by A. Quarteroni and published by Springer Science & Business Media. This book was released on 2007-03-20 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematicalmodelingofhumanphysiopathologyisatremendouslyambitioustask. It encompasses the modeling of most diverse compartments such as the cardiovas- lar,respiratory,skeletalandnervoussystems,aswellasthemechanicalandbioch- ical interaction between blood ?ow and arterial walls, and electrocardiac processes and electric conduction in biological tissues. Mathematical models can be set up to simulate both vasculogenesis (the aggregation and organization of endothelial cells dispersed in a given environment) and angiogenesis (the formation of new vessels sprouting from an existing vessel) that are relevant to the formation of vascular networks, and in particular to the description of tumor growth. The integration of models aimed at simulating the cooperation and interrelation of different systems is an even more dif?cult task. It calls for the setting up of, for instance, interaction models for the integrated cardio-vascular system and the interplay between the central circulation and peripheral compartments, models for the mid-to-long range cardiovascular adjustments to pathological conditions (e.g., to account for surgical interventions, congenital malformations, or tumor growth), models for integration among circulation, tissue perfusion, biochemical and thermal regulation, models for parameter identi?cation and sensitivity analysis to parameter changes or data uncertainty – and many others.

Encyclopedia of Complexity and Systems Science

Download Encyclopedia of Complexity and Systems Science PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 9780387758886
Total Pages : 10398 pages
Book Rating : 4.7/5 (588 download)

DOWNLOAD NOW!


Book Synopsis Encyclopedia of Complexity and Systems Science by :

Download or read book Encyclopedia of Complexity and Systems Science written by and published by Springer. This book was released on 2009-06-26 with total page 10398 pages. Available in PDF, EPUB and Kindle. Book excerpt: This encyclopedia provides an authoritative single source for understanding and applying the concepts of complexity theory together with the tools and measures for analyzing complex systems in all fields of science and engineering. It links fundamental concepts of mathematics and computational sciences to applications in the physical sciences, engineering, biomedicine, economics and the social sciences.

A Systems Approach to Biomedicine

Download A Systems Approach to Biomedicine PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 652 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis A Systems Approach to Biomedicine by : William B. Blesser

Download or read book A Systems Approach to Biomedicine written by William B. Blesser and published by . This book was released on 1969 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Approaching Complex Diseases

Download Approaching Complex Diseases PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030328570
Total Pages : 493 pages
Book Rating : 4.0/5 (33 download)

DOWNLOAD NOW!


Book Synopsis Approaching Complex Diseases by : Mariano Bizzarri

Download or read book Approaching Complex Diseases written by Mariano Bizzarri and published by Springer Nature. This book was released on 2020-04-17 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.

Knowledge-Based Systems in Biomedicine and Computational Life Science

Download Knowledge-Based Systems in Biomedicine and Computational Life Science PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3642330150
Total Pages : 221 pages
Book Rating : 4.6/5 (423 download)

DOWNLOAD NOW!


Book Synopsis Knowledge-Based Systems in Biomedicine and Computational Life Science by : Tuan D. Pham

Download or read book Knowledge-Based Systems in Biomedicine and Computational Life Science written by Tuan D. Pham and published by Springer. This book was released on 2012-12-14 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a sample of research on knowledge-based systems in biomedicine and computational life science. The contributions include: personalized stress diagnosis system, image analysis system for breast cancer diagnosis, analysis of neuronal cell images, structure prediction of protein, relationship between two mental disorders, detection of cardiac abnormalities, holistic medicine based treatment and analysis of life-science data.

Philosophy of Complex Systems

Download Philosophy of Complex Systems PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 9780080931227
Total Pages : 952 pages
Book Rating : 4.9/5 (312 download)

DOWNLOAD NOW!


Book Synopsis Philosophy of Complex Systems by :

Download or read book Philosophy of Complex Systems written by and published by Elsevier. This book was released on 2011-05-23 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: The domain of nonlinear dynamical systems and its mathematical underpinnings has been developing exponentially for a century, the last 35 years seeing an outpouring of new ideas and applications and a concomitant confluence with ideas of complex systems and their applications from irreversible thermodynamics. A few examples are in meteorology, ecological dynamics, and social and economic dynamics. These new ideas have profound implications for our understanding and practice in domains involving complexity, predictability and determinism, equilibrium, control, planning, individuality, responsibility and so on. Our intention is to draw together in this volume, we believe for the first time, a comprehensive picture of the manifold philosophically interesting impacts of recent developments in understanding nonlinear systems and the unique aspects of their complexity. The book will focus specifically on the philosophical concepts, principles, judgments and problems distinctly raised by work in the domain of complex nonlinear dynamical systems, especially in recent years. -Comprehensive coverage of all main theories in the philosophy of Complex Systems -Clearly written expositions of fundamental ideas and concepts -Definitive discussions by leading researchers in the field -Summaries of leading-edge research in related fields are also included

The Value of Systems and Complexity Sciences for Healthcare

Download The Value of Systems and Complexity Sciences for Healthcare PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3319262211
Total Pages : 285 pages
Book Rating : 4.3/5 (192 download)

DOWNLOAD NOW!


Book Synopsis The Value of Systems and Complexity Sciences for Healthcare by : Joachim P Sturmberg

Download or read book The Value of Systems and Complexity Sciences for Healthcare written by Joachim P Sturmberg and published by Springer. This book was released on 2016-03-01 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This visionary reframing of health and healthcare uses a complexity science approach to building healthcare systems that are accessible, effective, and prepared for change and challenges. Its holistic map for understanding the human organism emphasizes the interconnectedness of the individual’s physical, psychological, cognitive, and sociocultural functioning. Applications of this approach are described in primary, specialist, and emergency care and at the organizational and policy levels, from translating findings to practice, to problem solving and evaluation. In this model, the differences between disease and illness and treating illness and restoring health are not mere wordplay, but instead are robust concepts reflecting real-world issues and their solutions. Based on the Proceedings of the 1st International Conference of Systems and Complexity for Healthcare, topics covered include: • Coping with complexity and uncertainty: insights from studying epidemiology in family medicine • Anticipation in complex systems: potential implications for improving safety and quality in healthcare • Monitoring variability and complexity at the bedside • Viewing mental health through the lens of complexity science • Ethical complexities in systems healthcare: what care and for whom? • The value of systems and complexity thinking to enable change in adaptive healthcare organizations supported by informatics • If the facts don’t fit the theory, change the theory: implications for health system reform The Value of Systems and Complexity Sciences for Healthcare will interest and inspire health and disease researchers, health professionals, health care planners, health system financiers, health system administrators, health services administrators, health professional educators, and, last but not least, current and future patients.

Signals and Systems Analysis In Biomedical Engineering

Download Signals and Systems Analysis In Biomedical Engineering PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 1439812535
Total Pages : 656 pages
Book Rating : 4.4/5 (398 download)

DOWNLOAD NOW!


Book Synopsis Signals and Systems Analysis In Biomedical Engineering by : Robert B. Northrop

Download or read book Signals and Systems Analysis In Biomedical Engineering written by Robert B. Northrop and published by CRC Press. This book was released on 2016-04-19 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this text, based on the author's 30 years of teaching and research on neurosensory systems, helped biomedical engineering students and professionals strengthen their skills in the common network of applied mathematics that ties together the diverse disciplines that comprise this field. Updated and revised to include new materia

Complex Systems and Computational Biology Approaches to Acute Inflammation

Download Complex Systems and Computational Biology Approaches to Acute Inflammation PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 9781489987594
Total Pages : 304 pages
Book Rating : 4.9/5 (875 download)

DOWNLOAD NOW!


Book Synopsis Complex Systems and Computational Biology Approaches to Acute Inflammation by : Yoram Vodovotz

Download or read book Complex Systems and Computational Biology Approaches to Acute Inflammation written by Yoram Vodovotz and published by Springer. This book was released on 2013-07-04 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: