Company Profiles Symbio Pharmaceuticals Limited

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New Frontiers in Cancer Therapies: Focus on Transcription Factors, GTPases, Phosphatases and GPCRs, 2018-2030

Author : Roots Analysis
Publisher : Roots Analysis
ISBN 13 :
Total Pages : 306 pages
Book Rating : 4./5 ( download)

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Book Synopsis New Frontiers in Cancer Therapies: Focus on Transcription Factors, GTPases, Phosphatases and GPCRs, 2018-2030 by : Roots Analysis

Download or read book New Frontiers in Cancer Therapies: Focus on Transcription Factors, GTPases, Phosphatases and GPCRs, 2018-2030 written by Roots Analysis and published by Roots Analysis. This book was released on 2018-05-01 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ‘New Frontiers in Cancer Therapies: Focus on Transcription Factors, GTPases, Phosphatases and GPCRs, 2018-2030’ report provides a comprehensive study on the current market and therapeutic potential of the various pharmacological interventions designed against difficult-to-modulate cancer targets. It features an elaborate discussion on the future potential of this evolving domain, focusing on phosphatases, transcription factors, small GTPases (specifically Ras family) and undruggable G-protein coupled receptors (GPCRs). One of the key objectives of the study was to review and quantify the future opportunity for the ongoing product development programs of both small and big pharmaceutical firms. Amongst other elements, the report features: 1) A detailed assessment of the current market landscape of drugs being developed against various undruggable cancer targets, featuring information on the developer, phase of development (clinical, preclinical or discovery stage) of product candidate(s), information on type of molecule(s), biological target(s), mechanism of action, route of administration, and key therapeutic indication(s). 2) Elaborate profiles of key companies (selected based on pipeline strength); each profile features an overview of the company, details on it product portfolio, technology overview (wherever applicable), detailed information on advanced stage pipeline candidates (featuring a drug overview, clinical trial information and recent developments) and a comprehensive future outlook. 3) A section on emerging technologies and platforms that are aiding the development of therapies capable of targeting biological molecules which were previously considered as undruggable. 4) A detailed publication analysis on more than 70 research articles that have been published between January 2014 and March 2018, highlighting the key focus areas (biological targets and indications) of the ongoing research activity in this field. 5) An analysis of the partnerships that have been established in this domain in the recent past, covering R&D agreements, license agreements, clinical trial collaborations, mergers and acquisitions, and other relevant agreements. 6) An analysis of the investments made at various stages of development in companies that are focused in this area, including seed financing, venture capital financing, debt financing, grants, capital raised from IPOs and subsequent offerings. 7) A compilation of key insights derived based on various parameters; these include [A] a bull’s eye analysis highlighting the distribution of pipeline candidates in terms of phase of development, type of target family and type of molecule [B] a three-dimensional and five-dimensional spider web analyses of candidate therapeutics based on different parameters, namely number of publications, grants awarded to promote development, active clinical trials, current phase of development and the number of companies developing drugs against various undruggable targets, and [C] a world map representation, depicting the most active geographies in terms of the presence of companies developing drug candidates against difficult-to-modulate cancer targets.

Fungi

Author : Kevin Kavanagh
Publisher : John Wiley & Sons
ISBN 13 : 111997769X
Total Pages : 315 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Fungi by : Kevin Kavanagh

Download or read book Fungi written by Kevin Kavanagh and published by John Wiley & Sons. This book was released on 2011-08-04 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi: Biology and Applications, Second Edition provides a comprehensive treatment of fungi, covering biochemistry, genetics and the medical and economic significance of these organisms at introductory level. With no prior knowledge of the subject assumed, the opening chapters offer a broad overview of the basics of fungal biology, in particular the physiology and genetics of fungi and also a new chapter on the application of genomics to fungi. Later chapters move on to include more detailed coverage of topics such as antibiotic and chemical commodities from fungi, new chapters on biotechnological use of fungal enzymes and fungal proteomics, and fungal diseases of humans, antifungal agents for use in human therapy and fungal pathogens of plants.

Nelson Information's Directory of Investment Research

Author :
Publisher :
ISBN 13 :
Total Pages : 1448 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Nelson Information's Directory of Investment Research by :

Download or read book Nelson Information's Directory of Investment Research written by and published by . This book was released on 2006 with total page 1448 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multilingual Computing & Technology

Author :
Publisher :
ISBN 13 :
Total Pages : 556 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Multilingual Computing & Technology by :

Download or read book Multilingual Computing & Technology written by and published by . This book was released on 2005 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt:

LexisNexis Corporate Affiliations

Author :
Publisher :
ISBN 13 :
Total Pages : 2396 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis LexisNexis Corporate Affiliations by :

Download or read book LexisNexis Corporate Affiliations written by and published by . This book was released on 2004 with total page 2396 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Business @ the Speed of Thought

Author : Bill Gates
Publisher : Grand Central Publishing
ISBN 13 : 0446912808
Total Pages : 223 pages
Book Rating : 4.4/5 (469 download)

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Book Synopsis Business @ the Speed of Thought by : Bill Gates

Download or read book Business @ the Speed of Thought written by Bill Gates and published by Grand Central Publishing. This book was released on 2009-09-26 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: In his new book, Microsoft chairman and CEO Bill Gates discusses how technology can help run businesses better today and how it will transform the nature of business in the near future. Gates stresses the need for managers to view technology not as overhead but as a strategic asset, and offers detailed examples from Microsoft, GM, Dell, and many other successful companies. Companion Web site.

Commonwealth Of Australia Gazette

Author : Australia
Publisher :
ISBN 13 :
Total Pages : 1356 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Commonwealth Of Australia Gazette by : Australia

Download or read book Commonwealth Of Australia Gazette written by Australia and published by . This book was released on 1969 with total page 1356 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Passion for Ideas

Author : Heinrich von Pierer
Publisher : Purdue University Press
ISBN 13 : 9781557532091
Total Pages : 382 pages
Book Rating : 4.5/5 (32 download)

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Book Synopsis A Passion for Ideas by : Heinrich von Pierer

Download or read book A Passion for Ideas written by Heinrich von Pierer and published by Purdue University Press. This book was released on 2002 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Business and industry leaders are eager to find ways to spark the creative instinct in their work forces. The creation, implementation, and sustainability of new ideas is the lifeblood ensuring the growth and viability of any organization. Without continuing innovation, competitive advantage and global market share are endangered. Once-thriving organizations can find themselves unprepared for the future. This newly translated work examines the multi-layered environment of innovation by melding the thoughts of business management pundits like Peter Senge with the views of artist, politicians, and other non-traditional thinkers like Tao Ho, Peter Greenaway, and Wolfgang Rihm. These thought leaders share their insights and help us to understand the process of creativity and construction and the methods to move organizations forward in an ever-changing climate.

Encyclopedia of Infectious Diseases

Author : Michel Tibayrenc
Publisher : John Wiley & Sons
ISBN 13 : 0470114193
Total Pages : 807 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Encyclopedia of Infectious Diseases by : Michel Tibayrenc

Download or read book Encyclopedia of Infectious Diseases written by Michel Tibayrenc and published by John Wiley & Sons. This book was released on 2007-07-31 with total page 807 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how the application of novel multidisciplinary, integrative approaches and technologies are dramatically changing our understanding of the pathogenesis of infectious diseases and their treatments. Each article presents the state of the science, with a strong emphasis on new and emerging medical applications. The Encyclopedia of Infectious Diseases is organized into five parts. The first part examines current threats such as AIDS, malaria, SARS, and influenza. The second part addresses the evolution of pathogens and the relationship between human genetic diversity and the spread of infectious diseases. The next two parts highlight the most promising uses of molecular identification, vector control, satellite detection, surveillance, modeling, and high-throughput technologies. The final part explores specialized topics of current concern, including bioterrorism, world market and infectious diseases, and antibiotics for public health. Each article is written by one or more leading experts in the field of infectious diseases. These experts place all the latest findings from various disciplines in context, helping readers understand what is currently known, what the next generation of breakthroughs is likely to be, and where more research is needed. Several features facilitate research and deepen readers' understanding of infectious diseases: Illustrations help readers understand the pathogenesis and diagnosis of infectious diseases Lists of Web resources serve as a gateway to important research centers, government agencies, and other sources of information from around the world Information boxes highlight basic principles and specialized terminology International contributions offer perspectives on how infectious diseases are viewed by different cultures A special chapter discusses the representation of infectious diseases in art With its multidisciplinary approach, this encyclopedia helps point researchers in new promising directions and helps health professionals better understand the nature and treatment of infectious diseases.

How the Body Shapes the Way We Think

Author : Rolf Pfeifer
Publisher : MIT Press
ISBN 13 : 0262288524
Total Pages : 419 pages
Book Rating : 4.2/5 (622 download)

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Book Synopsis How the Body Shapes the Way We Think by : Rolf Pfeifer

Download or read book How the Body Shapes the Way We Think written by Rolf Pfeifer and published by MIT Press. This book was released on 2006-10-27 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exploration of embodied intelligence and its implications points toward a theory of intelligence in general; with case studies of intelligent systems in ubiquitous computing, business and management, human memory, and robotics. How could the body influence our thinking when it seems obvious that the brain controls the body? In How the Body Shapes the Way We Think, Rolf Pfeifer and Josh Bongard demonstrate that thought is not independent of the body but is tightly constrained, and at the same time enabled, by it. They argue that the kinds of thoughts we are capable of have their foundation in our embodiment—in our morphology and the material properties of our bodies. This crucial notion of embodiment underlies fundamental changes in the field of artificial intelligence over the past two decades, and Pfeifer and Bongard use the basic methodology of artificial intelligence—"understanding by building"—to describe their insights. If we understand how to design and build intelligent systems, they reason, we will better understand intelligence in general. In accessible, nontechnical language, and using many examples, they introduce the basic concepts by building on recent developments in robotics, biology, neuroscience, and psychology to outline a possible theory of intelligence. They illustrate applications of such a theory in ubiquitous computing, business and management, and the psychology of human memory. Embodied intelligence, as described by Pfeifer and Bongard, has important implications for our understanding of both natural and artificial intelligence.

Clinical Trials with Missing Data

Author : Michael O'Kelly
Publisher : John Wiley & Sons
ISBN 13 : 1118762533
Total Pages : 472 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Clinical Trials with Missing Data by : Michael O'Kelly

Download or read book Clinical Trials with Missing Data written by Michael O'Kelly and published by John Wiley & Sons. This book was released on 2014-02-14 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides practical guidance for statisticians, clinicians, and researchers involved in clinical trials in the biopharmaceutical industry, medical and public health organisations. Academics and students needing an introduction to handling missing data will also find this book invaluable. The authors describe how missing data can affect the outcome and credibility of a clinical trial, show by examples how a clinical team can work to prevent missing data, and present the reader with approaches to address missing data effectively. The book is illustrated throughout with realistic case studies and worked examples, and presents clear and concise guidelines to enable good planning for missing data. The authors show how to handle missing data in a way that is transparent and easy to understand for clinicians, regulators and patients. New developments are presented to improve the choice and implementation of primary and sensitivity analyses for missing data. Many SAS code examples are included – the reader is given a toolbox for implementing analyses under a variety of assumptions.

Desk Encyclopedia of Microbiology

Author : Moselio Schaechter
Publisher : Academic Press
ISBN 13 : 0080961282
Total Pages : 1277 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Desk Encyclopedia of Microbiology by : Moselio Schaechter

Download or read book Desk Encyclopedia of Microbiology written by Moselio Schaechter and published by Academic Press. This book was released on 2010-04-19 with total page 1277 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Desk Encyclopedia of Microbiology, Second Edition is a single-volume comprehensive guide to microbiology for the advanced reader. Derived from the six volume e-only Encyclopedia of Microbiology, Third Edition, it bridges the gap between introductory texts and specialized reviews. Covering topics ranging from the basic science of microbiology to the current "hot" topics in the field, it will be invaluable for obtaining background information on a broad range of microbiological topics, preparing lectures and preparing grant applications and reports. - The most comprehensive single-volume source providing an overview of microbiology to non-specialists - Bridges the gap between introductory texts and specialized reviews - Provides concise and general overviews of important topics within the field making it a helpful resource when preparing for lectures, writing reports, or drafting grant applications

War, Will, and Warlords

Author :
Publisher : Government Printing Office
ISBN 13 : 9780160915574
Total Pages : 292 pages
Book Rating : 4.9/5 (155 download)

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Book Synopsis War, Will, and Warlords by :

Download or read book War, Will, and Warlords written by and published by Government Printing Office. This book was released on with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compares the reasons for and the responses to the insurgencies in Afghanistan and Pakistan since October 2001. Also examines the lack of security and the support of insurgent groups in Afghanistan and Pakistan since the 1970s that explain the rise of the Pakistan-supported Taliban. Explores the border tribal areas between the two countries and how they influence regional stability and U.S. security. Explains the implications of what happened during this 10-year period to provide candid insights on the prospects and risks associated with bringing a durable stability to this area of the world.

Fundamentals of Enzyme Engineering

Author : Young Je Yoo
Publisher : Springer
ISBN 13 : 9402410260
Total Pages : 208 pages
Book Rating : 4.4/5 (24 download)

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Book Synopsis Fundamentals of Enzyme Engineering by : Young Je Yoo

Download or read book Fundamentals of Enzyme Engineering written by Young Je Yoo and published by Springer. This book was released on 2017-01-12 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive introduction to all aspects of enzyme engineering, from fundamental principles through to the state-of-the-art in research and industrial applications. It begins with a brief history, describing the milestones of advancement in enzyme science and technology, before going on to cover the fundamentals of enzyme chemistry, the biosynthesis of enzymes and their production. Enzyme stability and the reaction kinetics during enzymatic reactions are presented to show how enzymes function during catalysis and the factors that affect their activity. Methods to improve enzyme performance are also presented, such as cofactor regeneration and enzyme immobilization. The book emphasizes and elaborates on the performance and characteristics of enzymes at the molecular level. Finally, the book presents recent advances in enzyme engineering and some key industrial application of enzymes addressing the present needs of society. This book presents essential information not only for undergraduate and graduate students, but also for researchers in academia and industry, providing a valuable reference for the development of commercial applications of enzyme technology.

Staying with the Trouble

Author : Donna J. Haraway
Publisher : Duke University Press
ISBN 13 : 0822373785
Total Pages : 228 pages
Book Rating : 4.8/5 (223 download)

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Book Synopsis Staying with the Trouble by : Donna J. Haraway

Download or read book Staying with the Trouble written by Donna J. Haraway and published by Duke University Press. This book was released on 2016-08-25 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the midst of spiraling ecological devastation, multispecies feminist theorist Donna J. Haraway offers provocative new ways to reconfigure our relations to the earth and all its inhabitants. She eschews referring to our current epoch as the Anthropocene, preferring to conceptualize it as what she calls the Chthulucene, as it more aptly and fully describes our epoch as one in which the human and nonhuman are inextricably linked in tentacular practices. The Chthulucene, Haraway explains, requires sym-poiesis, or making-with, rather than auto-poiesis, or self-making. Learning to stay with the trouble of living and dying together on a damaged earth will prove more conducive to the kind of thinking that would provide the means to building more livable futures. Theoretically and methodologically driven by the signifier SF—string figures, science fact, science fiction, speculative feminism, speculative fabulation, so far—Staying with the Trouble further cements Haraway's reputation as one of the most daring and original thinkers of our time.

Animacies

Author : Mel Y. Chen
Publisher : Duke University Press
ISBN 13 : 0822352729
Total Pages : 311 pages
Book Rating : 4.8/5 (223 download)

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Book Synopsis Animacies by : Mel Y. Chen

Download or read book Animacies written by Mel Y. Chen and published by Duke University Press. This book was released on 2012-07-10 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rethinks the criteria governing agency and receptivity, health and toxicity, productivity and stillness

Warfare in the American Homeland

Author : Joy James
Publisher : Duke University Press
ISBN 13 : 9780822339236
Total Pages : 414 pages
Book Rating : 4.3/5 (392 download)

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Book Synopsis Warfare in the American Homeland by : Joy James

Download or read book Warfare in the American Homeland written by Joy James and published by Duke University Press. This book was released on 2007-07-20 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: DIVA collection of writings by prisoners and scholars that documents the extension of the violence and the repression of the prison establishment into the larger society. /div