Antiviral Drug Discovery and Development

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Author :
Publisher : Springer Nature
ISBN 13 : 9811602670
Total Pages : 357 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Antiviral Drug Discovery and Development by : Xinyong Liu

Download or read book Antiviral Drug Discovery and Development written by Xinyong Liu and published by Springer Nature. This book was released on 2021-07-13 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced clinical development. Special attention is paid to viral infections with a high impact on the world population or highly relevant from the public health perspective (HIV, hepatitis C, influenza virus, etc.). In these chapters, limitations associated with adverse effects and emergence of drug resistance are discussed in detail. In addition to classical antiviral strategies, chapters will be dedicated to discuss the non-classical drug development strategies to block viral infection, for instance, allosteric inhibitors, covalent antiviral agents, or antiviral compounds targeting protein–protein interactions. Finally, current prospects for producing broad-spectrum antiviral inhibitors will be also addressed. The book is distinctive in providing the most recent update in the rapidly evolving field of antiviral therapeutics. Authoritative reviews are written by international scientists well known for their contributions in their topics of research, which makes this book suitable for researchers not only within the antiviral research community but also attractive to a broad audience in the drug discovery field. This book covers molecular structures and biochemical mechanisms mediating the antiviral effects, while discussing various ligand design strategies, which include traditional medicinal chemistry, computational chemistry, and chemical biology approaches. The book provides a comprehensive review of antiviral drug discovery and development approaches, particularly focusing on current innovations and future trends.

Anterior Skull Base Tumors

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318066702
Total Pages : 266 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Anterior Skull Base Tumors by : P. Nicolai

Download or read book Anterior Skull Base Tumors written by P. Nicolai and published by Karger Medical and Scientific Publishers. This book was released on 2020-07-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, interest in the management of anterior skull base tumors has been fostered by the introduction and subsequent rapid expansion of indications of transnasal endoscopic techniques. In parallel, extraordinary progress has been made in all the other disciplines which are involved in the complex process of managing anterior skull base tumors, leading to substantial improvements in diagnosis and treatment. The anterior skull base can be involved in a large variety of tumors of a varying nature and histology, which in the majority of cases originate from adjacent anatomic sites. In fact, primary lesions of the anterior skull base mainly include osteoma and other tumors originating from bone and cartilage. Tumors involving the anterior skull base have their origin prevalently in the sinonasal tract, but lesions developing on the intracranial site, such as meningiomas, may also extend caudally to encroach upon this area. All these lesions are rare, which means that the pertinent literature does not include prospective studies or treatment guidelines based on a high level of evidence. In view of the extreme histological variability of lesions involving the anterior skull base, much emphasis has been placed on addressing the different nuances of treatment in relation to histology, especially for malignant tumors. The chapters focusing on surgery provide divergent views on selection criteria for a specific surgical technique, which is the aim of this publication.

Clinical Virology

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Publisher : John Wiley & Sons
ISBN 13 : 1555819435
Total Pages : 1473 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Clinical Virology by : Douglas D. Richman

Download or read book Clinical Virology written by Douglas D. Richman and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 1473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential reference of clinical virology Virology is one of the most dynamic and rapidly changing fields of clinical medicine. For example, sequencing techniques from human specimens have identified numerous new members of several virus families, including new polyomaviruses, orthomyxoviruses, and bunyaviruses. Clinical Virology, Fourth Edition, has been extensively revised and updated to incorporate the latest developments and relevant research. Chapters written by internationally recognized experts cover novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention, organized into two major sections: Section 1 provides information regarding broad topics in virology, including immune responses, vaccinology, laboratory diagnosis, principles of antiviral therapy, and detailed considerations of important organ system manifestations and syndromes caused by viral infections. Section 2 provides overviews of specific etiologic agents and discusses their biology, epidemiology, pathogenesis of disease causation, clinical manifestations, laboratory diagnosis, and management. Clinical Virology provides the critical information scientists and health care professionals require about all aspects of this rapidly evolving field.

A Century of Progress in Head and Neck Cancer

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Author :
Publisher : JP Medical Ltd
ISBN 13 : 9351523128
Total Pages : 341 pages
Book Rating : 4.3/5 (515 download)

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Book Synopsis A Century of Progress in Head and Neck Cancer by : Jatin P Shah

Download or read book A Century of Progress in Head and Neck Cancer written by Jatin P Shah and published by JP Medical Ltd. This book was released on 2014-08-31 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guide to advances in diagnosis and treatment of head and neck cancers over last century. Led by New York specialist, numerous experts provide commentary on 100 contributory articles.

Cyclotron Produced Radionuclides

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Publisher :
ISBN 13 : 9789201002082
Total Pages : 0 pages
Book Rating : 4.0/5 (2 download)

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Book Synopsis Cyclotron Produced Radionuclides by :

Download or read book Cyclotron Produced Radionuclides written by and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive treatment of cyclotrons, with a special emphasis on production of radionuclides. Individual sections are devoted to accelerator technology, theoretical aspects of nuclear reactions, the technology behind targetry, techniques for preparation of targets, irradiation of targets under high beam currents, target processing and target recovery. This book will appeal to scientists and technologists interested in translating cyclotron technology into practice, as well as postgraduate students in this field.

Innovation in Information Systems and Technologies to Support Learning Research

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Publisher : Springer Nature
ISBN 13 : 3030367789
Total Pages : 659 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Innovation in Information Systems and Technologies to Support Learning Research by : Mohammed Serrhini

Download or read book Innovation in Information Systems and Technologies to Support Learning Research written by Mohammed Serrhini and published by Springer Nature. This book was released on 2019-11-30 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides glimpses into contemporary research in information systems & technology, learning, artificial intelligence (AI), machine learning, and security and how it applies to the real world, but the ideas presented also span the domains of telehealth, computer vision, the role and use of mobile devices, brain–computer interfaces, virtual reality, language and image processing and big data analytics and applications. Great research arises from asking pertinent research questions. This book reveals some of the authors’ “beautiful questions” and how they develop the subsequent “what if” and “how” questions, offering readers food for thought and whetting their appetite for further research by the same authors.

Improving Outcomes in Oral Cancer

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Publisher : Springer Nature
ISBN 13 : 3030300943
Total Pages : 189 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Improving Outcomes in Oral Cancer by : Deepak Kademani

Download or read book Improving Outcomes in Oral Cancer written by Deepak Kademani and published by Springer Nature. This book was released on 2019-11-13 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together experts in the field of maxillofacial and head and neck oncology to provide a comprehensive clinical and translational update on oral cancer that focuses especially on prognosis. Readers will find up-to-date information on disease staging and the pathological, genetic, and surgical factors that affect patient outcomes. Individual chapters describe the most recent advances in radiotherapy, chemotherapy, and immunotherapy, again with careful analysis of the treatment-related factors relevant to response and survival. Management of premalignant lesions and risk factors for malignant transformation are discussed, and the latest knowledge on chemoprevention is presented. Further topics to be addressed include reconstruction of oral cancer defects, salvage options in the event of recurrence, and the prediction of quality of life following treatment. The book will be of value to all clinicians who care for patients with oral cancer in their everyday practice.

3D Printing of Pharmaceuticals and Drug Delivery Devices

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Author :
Publisher : MDPI
ISBN 13 : 3039364235
Total Pages : 436 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis 3D Printing of Pharmaceuticals and Drug Delivery Devices by : Dimitrios A. Lamprou

Download or read book 3D Printing of Pharmaceuticals and Drug Delivery Devices written by Dimitrios A. Lamprou and published by MDPI. This book was released on 2020-07-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 3D printing (3DP) process was patented in 1986; however, only in the last decade has it begun to be used for medical applications, as well as in the fields of prosthetics, bio-fabrication, and pharmaceutical printing. 3DP or additive manufacturing (AM) is a family of technologies that implement layer-by-layer processes in order to fabricate physical models based on a computer aided design (CAD) model. 3D printing permits the fabrication of high degrees of complexity with great reproducibility in a fast and cost-effective fashion. 3DP technology offers a new paradigm for the direct manufacture of individual dosage forms and has the potential to allow for variations in size and geometry as well as control dose and release behavior. Furthermore, the low cost and ease of use of 3DP systems means that the possibility of manufacturing medicines and medical devices at the point of dispensing or at the point of use could become a reality. 3DP thus offers the perfect innovative manufacturing route to address the critical capability gap that hinders the widespread exploitation of personalized medicines for molecules that are currently not easy to deliver. This Special Issue will address new developments in the area of 3D printing and bioprinting for drug delivery applications, covering the recent advantages and future directions of additive manufacturing for pharmaceutical products.

Human Papillomavirus and Related Diseases

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 953307860X
Total Pages : 364 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Human Papillomavirus and Related Diseases by : Davy Vanden Broeck

Download or read book Human Papillomavirus and Related Diseases written by Davy Vanden Broeck and published by BoD – Books on Demand. This book was released on 2012-01-20 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cervical cancer is the second most prevalent cancer among women worldwide, and infection with Human Papilloma Virus (HPV) has been identified as the causal agent for this condition. The natural history of cervical cancer is characterized by slow disease progression, rendering the condition, in essence, preventable and even treatable when diagnosed in early stages. Pap smear and the recently introduced prophylactic vaccines are the most prominent prevention options, but despite the availability of these primary and secondary screening tools, the global burden of disease is unfortunately still very high. This book will focus on the clinical aspects of HPV and related disease, highlighting the latest developments in this field.

U.S. Investment in Biotechnology

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Publisher :
ISBN 13 :
Total Pages : 308 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis U.S. Investment in Biotechnology by : United States. Congress. Office of Technology Assessment

Download or read book U.S. Investment in Biotechnology written by United States. Congress. Office of Technology Assessment and published by . This book was released on 1988 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:

New Developments in Biotechnology: U.S. Investment in biotechnology (Summary)

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Author :
Publisher :
ISBN 13 :
Total Pages : 306 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis New Developments in Biotechnology: U.S. Investment in biotechnology (Summary) by :

Download or read book New Developments in Biotechnology: U.S. Investment in biotechnology (Summary) written by and published by . This book was released on 1988 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Head and Neck Surgery and Oncology

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323055893
Total Pages : 859 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Head and Neck Surgery and Oncology by : Jatin P. Shah

Download or read book Head and Neck Surgery and Oncology written by Jatin P. Shah and published by Elsevier Health Sciences. This book was released on 2012-01-01 with total page 859 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rev. ed. of: Head and neck surgery and oncology. 3rd ed. 2003.

Progress in Cancer Immunotherapy

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Publisher : Springer
ISBN 13 : 9401775559
Total Pages : 293 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Progress in Cancer Immunotherapy by : Shuren Zhang

Download or read book Progress in Cancer Immunotherapy written by Shuren Zhang and published by Springer. This book was released on 2016-05-30 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers an extensive overview of recent progress in basic and clinical research on cancer immunotherapy. Thanks to rapid advances in molecular biology and immunology, it has become increasingly evident that cancer growth is influenced by host immune responses. With the success of a number of clinical trials, immunotherapy has become a promising treatment modality of cancer. This book covers five major topics, including monoclonal antibodies, biological response modifiers, cancer vaccines, adoptive cellular therapy and oncolytic viruses. It also examines the combination of different immune strategies as well as the combination of immunotherapy with other treatments to increase anti-tumor effects. Through the comprehensive discussion of the topic, the book sheds valuable new light on the treatment of tumors.

Proceedings of International Conference on Intelligent Manufacturing and Automation

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Publisher : Springer Nature
ISBN 13 : 9811544859
Total Pages : 831 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Proceedings of International Conference on Intelligent Manufacturing and Automation by : Hari Vasudevan

Download or read book Proceedings of International Conference on Intelligent Manufacturing and Automation written by Hari Vasudevan and published by Springer Nature. This book was released on 2020-06-30 with total page 831 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers selected papers presented at the Second International Conference on Intelligent Manufacturing and Automation (ICIMA 2020), which was jointly organized by the Departments of Mechanical Engineering and Production Engineering at Dwarkadas J. Sanghvi College of Engineering (DJSCE), Mumbai, and by the Indian Society of Manufacturing Engineers (ISME). Covering a range of topics in intelligent manufacturing, automation, advanced materials and design, it focuses on the latest advances in e.g. CAD/CAM/CAE/CIM/FMS in manufacturing, artificial intelligence in manufacturing, IoT in manufacturing, product design & development, DFM/DFA/FMEA, MEMS & nanotechnology, rapid prototyping, computational techniques, nano- & micro-machining, sustainable manufacturing, industrial engineering, manufacturing process management, modelling & optimization techniques, CRM, MRP & ERP, green, lean & agile manufacturing, logistics & supply chain management, quality assurance & environmental protection, advanced material processing & characterization of composite & smart materials. The book is intended as a reference guide for future researchers, and as a valuable resource for students in graduate and doctoral programmes.

Squamous Cell Head and Neck Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 1592599389
Total Pages : 357 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Squamous Cell Head and Neck Cancer by : David J. Adelstein

Download or read book Squamous Cell Head and Neck Cancer written by David J. Adelstein and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading expert physicians and investigators from around the world review the state-of-the-art in the management of squamous cell head and neck cancer, with emphasis on coordinating different treatment modalities. The authors address several surgical issues, including laser-based surgery, larynx preservation approaches, salvage surgery, and neck management after non-operative treatment. They also discuss definitive radiation for larynx cancer, brachytherapy, altered fractionation radiation, intensity modulated radiation therapy, and the importance of tumor hypoxia, as well as the role of chemotherapy in sequential, concurrent, and adjuvant multi-modality treatment schedules. Other topics of special interest include targeted and gene therapies, multimodality management of nasopharyngeal cancer, chemoprevention, toxicity modification, quality of life outcomes, symptom palliation, and epidemiology.

Mapping our genes : the genome projects : how big, how fast?

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Author :
Publisher : DIANE Publishing
ISBN 13 : 142892258X
Total Pages : 215 pages
Book Rating : 4.4/5 (289 download)

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Book Synopsis Mapping our genes : the genome projects : how big, how fast? by :

Download or read book Mapping our genes : the genome projects : how big, how fast? written by and published by DIANE Publishing. This book was released on 1988 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Optimization of Pharmaceutical R&d Programs and Portfolios

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Author :
Publisher :
ISBN 13 : 9783319090764
Total Pages : 212 pages
Book Rating : 4.0/5 (97 download)

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Book Synopsis Optimization of Pharmaceutical R&d Programs and Portfolios by : Zoran Antonijevic

Download or read book Optimization of Pharmaceutical R&d Programs and Portfolios written by Zoran Antonijevic and published by . This book was released on 2014-10-31 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: