Collagen Quality of the Implant Site Bone Influences Tissue Responses in Vivo

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Collagen Quality of the Implant Site Bone Influences Tissue Responses in Vivo by : Suliman Mubarak

Download or read book Collagen Quality of the Implant Site Bone Influences Tissue Responses in Vivo written by Suliman Mubarak and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Back ground: Bone quality and quantity of the implant site are thought to be important to let osseointegration be established properly. Therefore we must pay attention to bone quality along with bone density and volume upon diagnosis. A major determinant of Bone quality is collagen quality that may influence the bone tissue responses and metabolism. However, the influence of bone quality in terms of collagen quality on the establishment of osseointegration has not been well understood Aim: To clarify the influences of collagen crosslink deficiency on bone response at the implant and its surrounding tissues in vivo.Materials and Methods: Four weeks old Wister male rats (n=24) were divided into test (n=12) and control groups (n=12). Animals were group housed in standard cages with free access to standard chow and water. To inhibit enzymatic cross-link formation in vivo, beta-aminopropionitrile (BAPN) was used. Test group were given water containing 0.1% BAPN and continued until the day of sacrificing. Control group were given normal water. After 4 weeks, all rats received a custom made machined surface titanium implants in both right and left tibias (n= 48). At 1,2,4 weeks after the surgery, rats were sacrificed and the specimens were prepared from retrieved tibias for decalcified histological sections and observed under a microscopy. All the animal experiments were conducted in compliance with the protocol reviewed by the Institutional Animal Care and Use Committee and approved by the President of our University. Results: Remodeling of the bone tissue adjacent to the installed implants in the cortical area seemed to be more active in the test group compared to the control yet, the quality and integrity of newly formed bone is questionable in the BAPN group. The Bone Implant Contact (BIC) was significantly higher in the control group. The total volume of newly formed bone in bone marrow area was higher in control group than test group. Interestingly, a tremendous amount of immature bone and chondritic tissue was formed on the outer surface of the bone in both groups. The number of adipocytes in bone marrow was much higher in test group through out the 3 time points. Conclusion: Collagen quality affected the bone tissues reactions in vivo and might affect the establishment of osseointegration in turn. Further studies would be required to clarify the direct evidence of these differences and to establish clinical implications.

Collagen Quality as a Major Factor of Bone Quality Influences the Outcome of Bone Transplantation in Vivo

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Collagen Quality as a Major Factor of Bone Quality Influences the Outcome of Bone Transplantation in Vivo by :

Download or read book Collagen Quality as a Major Factor of Bone Quality Influences the Outcome of Bone Transplantation in Vivo written by and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Background: Bone transplantation is occasionally required prior to implant installation. Since Autografting is thought to be a gold standard for bone augmentation, a proper understanding of the paradigms that affect the outcome of bone transplantation is important for better prognosis. It is believed that bone components other than Bone Mineral Density are also very important determinants of bone quality and one of those is collagen. The influence of collagen quality that possibly affects the outcome of bone grafting is still unknown.Aim and hypothesis: To understand the influences of collagen quality of bone on the prognosis of bone transplantation, we investigated the fate of transplanted bone and adjacent tissues at the recipient site along with the healing of the donor site.Methods and Materials Wister male Rats (n=48) 4 weeks old were divided into test group (n=24) and control group (n=24). 0.2% Beta- Aminoproperionitrile (BAPN) was dissolved in test group water for 4 weeks. Control & Test groups were subdivided equally in to 2 groups; Donor Group (DG) and Recipient Group (RG). The subdivision was made to resemble bone grafting/transplantation settings. Two 5mm diameter calvarial bone chips were harvested from DG and grafted on RG. At 1, 2 and 4 weeks after the surgery, rats were sacrificed and the specimens were prepared from retrieved calvaria for decalcified histological sections. The sections were prepared for observation under light microscopy and histomorphometry. Results: In test group of RG subdivision, bridging rates between transplanted bone chips and recipient surface were higher in the BAPN group compared to control at all time points. Regarding the tissue changes in the calvarial defects of DG subdivision, BAPN group showed faster tissue formation, and gap closure compared to control group. Conclusions and Clinical Implications: A low quality bone grafts could be selected for bone augmentation clinically. In addition, the low collagen quality bone might accelerate bone formation in vivo. However, the maintenance of these formed bones adjacent to such transplants is important and the long term outcome should be studied. The finding reflects the necessity to develop new clinical parameters and methods for comprehensive pre-operative assessment involving the collagen quality.

Bone Tissue Engineering

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Publisher : CRC Press
ISBN 13 : 1135501912
Total Pages : 500 pages
Book Rating : 4.1/5 (355 download)

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Book Synopsis Bone Tissue Engineering by : Jeffrey O. Hollinger

Download or read book Bone Tissue Engineering written by Jeffrey O. Hollinger and published by CRC Press. This book was released on 2004-10-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

The Influence of a Collagen Matrix on Osteogenesis by Bone Cells in Vitro and in Vivo and Its Effects on Implant Osseointegration

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (223 download)

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Book Synopsis The Influence of a Collagen Matrix on Osteogenesis by Bone Cells in Vitro and in Vivo and Its Effects on Implant Osseointegration by : Reynaldo Todescan

Download or read book The Influence of a Collagen Matrix on Osteogenesis by Bone Cells in Vitro and in Vivo and Its Effects on Implant Osseointegration written by Reynaldo Todescan and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bone Implant Interface

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Publisher : St. Louis ; Toronto : Moseby
ISBN 13 :
Total Pages : 408 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Bone Implant Interface by : Hugh U. Cameron

Download or read book Bone Implant Interface written by Hugh U. Cameron and published by St. Louis ; Toronto : Moseby. This book was released on 1994 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mimicking the Extracellular Matrix

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849738335
Total Pages : 422 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Mimicking the Extracellular Matrix by : Gregory H. Hudalla

Download or read book Mimicking the Extracellular Matrix written by Gregory H. Hudalla and published by Royal Society of Chemistry. This book was released on 2015-11-18 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials.

Implant Site Development

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Publisher : John Wiley & Sons
ISBN 13 : 0470963190
Total Pages : 862 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Implant Site Development by : Michael Sonick

Download or read book Implant Site Development written by Michael Sonick and published by John Wiley & Sons. This book was released on 2011-12-14 with total page 862 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the desire for dental implant therapy ever escalating, clinicians are faced with the challenge of augmenting deficient natural physiology to provide effective sites for implantation. Implant Site Development helps the clinician decide if, when, and how to create a ridge site amenable to implantation. This practical book offers solutions to many implant site preservation scenarios, discussing different treatment options, timing, a variety of materials and techniques, and their application to the clinical practice. With a unique integrated clinical approach, Implant Site Development covers a range of site development techniques. Highly illustrated, Implant Site Development presents diagrams and clinical photographs to aid with clinical judgment and will prove useful for any dental professional involved in implant therapy, from general practitioners to prosthodontists, but especially surgeons. This literature-based, yet user-friendly, reference will be indispensable to the novice or veteran clinician.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1808 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1808 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Immune Response to Implanted Materials and Devices

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Publisher : Springer
ISBN 13 : 3319454331
Total Pages : 254 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis The Immune Response to Implanted Materials and Devices by : Bruna Corradetti

Download or read book The Immune Response to Implanted Materials and Devices written by Bruna Corradetti and published by Springer. This book was released on 2016-11-30 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.

Osseointegration and Dental Implants

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Publisher : John Wiley & Sons
ISBN 13 : 0813804744
Total Pages : 444 pages
Book Rating : 4.8/5 (138 download)

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Book Synopsis Osseointegration and Dental Implants by : Asbjorn Jokstad

Download or read book Osseointegration and Dental Implants written by Asbjorn Jokstad and published by John Wiley & Sons. This book was released on 2009-03-03 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osseointegration and Dental Implants offers a comprehensive guide to the state of the art of implant dentistry. Based around the proceedings of the Toronto Osseointegration Conference Revisited, it gathers together information on all aspects of implant dentistry and osseointegration, from basic scientific background, such as the biology of osseointegration and the biomechanics of implant surface design, to clinical relevance, such as treatment planning, loading protocols, and patient rehabilitation. This unique book shows implant dentistry as it is today, in all its diverse clinical applications, and provides an expert discussion of what we know, what we think we know, and what we need to find out.

Principles of Bone Biology

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Publisher : Academic Press
ISBN 13 : 0080568750
Total Pages : 2074 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Principles of Bone Biology by : John P. Bilezikian

Download or read book Principles of Bone Biology written by John P. Bilezikian and published by Academic Press. This book was released on 2008-09-29 with total page 2074 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field The essential resource for anyone involved in the study of bones and bone diseases Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics Readers can easily search and locate information quickly as it will be online with this new edition

Bioactive Agents for Functionalization of Biomaterials for Precise Tissue Engineering

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Publisher : Frontiers Media SA
ISBN 13 : 2832512895
Total Pages : 348 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Bioactive Agents for Functionalization of Biomaterials for Precise Tissue Engineering by : Gang Wu

Download or read book Bioactive Agents for Functionalization of Biomaterials for Precise Tissue Engineering written by Gang Wu and published by Frontiers Media SA. This book was released on 2023-02-28 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Innovative Perspectives in Oral and Maxillofacial Surgery

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Publisher : Springer Nature
ISBN 13 : 3030757501
Total Pages : 480 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Innovative Perspectives in Oral and Maxillofacial Surgery by : Mark R. Stevens

Download or read book Innovative Perspectives in Oral and Maxillofacial Surgery written by Mark R. Stevens and published by Springer Nature. This book was released on 2021-07-30 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the latest technologies and developments in oral and maxillofacial surgery. It presents information in an easy-to-read format and meticulously details each surgical technique. Thorough and accurate chapters comprehensively present procedures and treatments step-by-step procedures objectively. Each chapter follows a consistent format of which includes the scientific documentation of the procedure through clinical studies, objective benefits for the patient, detailed explanations of the procedure, levels of treatment complexity according to the SAC (simple -advanced complex) classification, and cost-effectiveness of the procedure for the patient and clinician. Extensive images, figures, and tables supplement select chapters to aid in visual learning. Extensive and unique, Innovative Perspectives in Oral and Maxillofacial Surgery is a vital tool for all dental specialists ranging from undergraduate students to established oral maxillofacial surgeons.

Biomaterials and Tissue Engineering in Urology

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Publisher : CRC Press
ISBN 13 : 9781439801772
Total Pages : 0 pages
Book Rating : 4.8/5 (17 download)

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Book Synopsis Biomaterials and Tissue Engineering in Urology by : J. Denstedt

Download or read book Biomaterials and Tissue Engineering in Urology written by J. Denstedt and published by CRC Press. This book was released on 2009-06-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An invaluable resource for clinicians as well as for researchers in materials and biomedical devices, this text summarizes recent research on the use of biomaterials and tissue engineering in the treatment of urological disorders. Part one reviews the fundamentals including biofilms and encrustation formation. Part two then discusses recent advances in biomaterials and the design of urological devices such as metal ureteral stents, self-lubricating catheter materials, and penile implants. The final section addresses urological tissue engineering, covering artificial and natural biomaterials, nanotechnology, and placental stem cells used for the regeneration of urological tissue and organs.

Current Concepts in Dental Implantology

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Publisher : BoD – Books on Demand
ISBN 13 : 9535117416
Total Pages : 278 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Current Concepts in Dental Implantology by : Ilser Turkyilmaz

Download or read book Current Concepts in Dental Implantology written by Ilser Turkyilmaz and published by BoD – Books on Demand. This book was released on 2015-02-25 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implant dentistry has changed and enhanced significantly since the introduction of osseointegration concept with dental implants. Because the benefits of therapy became apparent, implant treatment earned a widespread acceptance. Therefore, the need for dental implants has caused a rapid expansion of the market worldwide. Dental implantology continues to excel with the developments of new surgical and prosthodontic techniques, and armamentarium. The purpose of this book named Current Concepts in Dental Implantology is to present a novel resource for dentists who want to replace missing teeth with dental implants. It is a carefully organized book, which blends basic science, clinical experience, and current and future concepts. This book includes ten chapters and our aim is to provide a valuable source for dental students, post-graduate residents and clinicians who want to know more about dental implants.

Biomechanics and Biomaterials in Orthopedics

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Publisher : Springer
ISBN 13 : 1848826648
Total Pages : 534 pages
Book Rating : 4.8/5 (488 download)

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Book Synopsis Biomechanics and Biomaterials in Orthopedics by : Dominique G. Poitout

Download or read book Biomechanics and Biomaterials in Orthopedics written by Dominique G. Poitout and published by Springer. This book was released on 2016-06-15 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the constant evolution of implant technology, and improvement in the production of allograft and bone substitutes, the armamentarium of the orthopaedic surgeon has significantly expanded. In particular, the recent involvement of nanotechnologies opens up the possibilities of new approaches in the interactive interfaces of implants. With many important developments occurring since the first edition of this well-received book, this updated resource informs orthopaedic practitioners on a wide range of biomechanical advances in one complete reference guide. Biomechanics and Biomaterials in Orthopedics, 2nd edition compiles the most prominent work in the discipline to offer newly-qualified orthopedic surgeons a summary of the fundamental skills that they will need to apply in their day-to-day work, while also updating the knowledge of experienced surgeons. This book covers both basic concepts concerning biomaterials and biomechanics as well as their clinical application and the experience from everyday practical use. This book will be of great value to specialists in orthopedics and traumatology, while also providing an important basis for graduate and postgraduate learning.

Joint Replacement Technology

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Publisher : Woodhead Publishing
ISBN 13 : 0128210834
Total Pages : 726 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Joint Replacement Technology by : Peter A. Revell

Download or read book Joint Replacement Technology written by Peter A. Revell and published by Woodhead Publishing. This book was released on 2021-07-28 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of Joint Replacement Technology provides a thoroughly updated review of recent developments in joint replacement technology. Joint replacement is a standard treatment for joint degradation and has improved the quality of life of millions of patients. Collaboration between clinicians and researchers is critical to its continued success and to meet the rising expectations of patients and surgeons.This edition covers a range of updated and new content, ranging from chapters on materials analysis and selection, to methodologies and techniques used for joint replacement and clinical challenges of replacing specific joints. Key topics include tribological considerations and experiments; challenges in joint bearing surfaces; cementless fixation techniques; healing responses to implants. Clinical challenges and perspectives are covered with the aid of case studies.Thanks to its widespread collaboration and international contributors, Joint Replacement Technology, Third Edition is useful for materials scientists and engineers in both academia and the biomedical industry. Chemists, clinicians, and other researchers in this area will also find this text invaluable. This third edition provides an updated comprehensive review of recent developments in joint replacement technology Reviews a range of specific joints, biological and mechanical issues and fixation techniques Includes revised and new content, such as sections on regulatory affairs, AI techniques and 3D printing