Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Cofactor Biosynthesis
Download Cofactor Biosynthesis full books in PDF, epub, and Kindle. Read online Cofactor Biosynthesis ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Cofactor Biosynthesis: A Mechanistic Perspective by :
Download or read book Cofactor Biosynthesis: A Mechanistic Perspective written by and published by Academic Press. This book was released on 2001-01-02 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: The longest running serial published by Academic Press continues its well-respected run with Volume 61, a special volume in which a guest editor has come on board and has assembled some well-known contributors who are international authorities in the field. Together they tackle some of the latest topics in the field such as riboflavin and folate biosynthesis, biotin and lipoic acid biosynthesis, nicotinamide adenine dinucleotide biosynthesis, biosynthesis of vitamin B6 and structurally related derivatives, pantothenic acid and coenzyme A biosynthesis, mechanistic biosynthesis of protein-derived redox cofactors, ascorbic acid biosynthesis, biosynthesis of menaquinone and ubiquinone - Vitamin B12 biosynthesis, biosynthesis of the methanogenic cofactors, and thiamin biosynthesis.
Book Synopsis Cofactor Biosynthesis by : Tadhg P. Begley
Download or read book Cofactor Biosynthesis written by Tadhg P. Begley and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biosynthesis written by F.J. Leeper and published by Springer Science & Business Media. This book was released on 2003-09-05 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concerned with discovering the chemical pathways of biosynthesis, this book devotes four chapters to the use of isotopes in biosynthetic research and the biosynthesis of enzyme cofactors and vitamin B12 and of reduced polyketides such as erythromycin. The topics covered demonstrate the revolution that has occurred in biosynthetic studies with the advent of gene cloning and overexpression. Yet the book also shows that the more classical approach to biosynthetic studies must go hand in hand with these new techniques.
Book Synopsis Molybdenum Enzymes by : Thomas G. Spiro
Download or read book Molybdenum Enzymes written by Thomas G. Spiro and published by Wiley-Interscience. This book was released on 1985-11-14 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 7 in the Metal Ions in Biology Series, divided into two parts, covers the nitrogenase enzyme complex and the molybdenum redox enzymes. Part one covers the chemistry of Mo-Fe-S clusters and their relationship to nitrogenase, cofactor chemistry and biochemistry of nitrogenase, spectroscopic and electrochemical studies of the Fe-Mo cofactor and Fe-S clusters, and more. Part Two surveys oxo-molybdenum chemistry, discusses the nature of the molybdo-pterin complex, and describes the characteristics of several of the Mo redox enzymes.
Book Synopsis Comprehensive Natural Products III by :
Download or read book Comprehensive Natural Products III written by and published by Elsevier. This book was released on 2020-07-22 with total page 4266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Natural Products III, Third Edition, Seven Volume Set updates and complements the previous two editions, including recent advances in cofactor chemistry, structural diversity of natural products and secondary metabolites, enzymes and enzyme mechanisms and new bioinformatics tools. Natural products research is a dynamic discipline at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids and enzymes. This book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community. Provides readers with an in-depth review of current natural products research and a critical insight into the future direction of the field Bridges the gap in knowledge by covering developments in the field since the second edition published in 2010 Split into 7 sections on key topics to allow students, researchers and professionals to find relevant information quickly and easily Ensures that the knowledge within is easily understood by and applicable to a large audience
Book Synopsis Inborn Metabolic Diseases by : K. Tada
Download or read book Inborn Metabolic Diseases written by K. Tada and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each disease-related chapter begins with a detailed description of the patient and the delineating symptoms used for establishing the diagnosis and differential diagnosis. The highly detailed figures illustrate the metabolic derangement in a uniform way, together with essential aspects of the genetics involved, thus affording clarification and better understanding of the treatment. Topics covered range from general aspects such as the clinical approach, emergency treatment, diagnostic procedures, and psychosocial care for the child and the family, to specific discussions of new modes of treatment, including liver, bone marrow transplantation and somatic gene therapy.
Book Synopsis Molybdenum Cofactors and Their role in the Evolution of Metabolic Pathways by : Luana Presta
Download or read book Molybdenum Cofactors and Their role in the Evolution of Metabolic Pathways written by Luana Presta and published by Springer. This book was released on 2015-05-07 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this brief, the authors explore and review the current knowledge regarding the role of molybdenum in the evolution of biological systems and their interaction with biogeochemical cycles. Special emphasis is placed on biological nitrogen fixation and the nitrogen element cycle. The origin and evolution of molybdenum cofactor biosynthetic pathways as well as the evolutionary significance of molybdenum containing enzymes appearance is analyzed. Original data regarding nitrogen fixation pathways and related enzymes molecular evolution processes is presented. The trace element molybdenum is essential for nearly all organisms and forms the catalytic center of a large variety of enzymes such as nitrogenase, nitrate reductases, sulphite oxidase and xanthine oxidoreductases.
Book Synopsis Molybdenum cofactor biosynthesis in E coli by : Deborah Jane Eaves
Download or read book Molybdenum cofactor biosynthesis in E coli written by Deborah Jane Eaves and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies on the Role of NifH in Iron-molybdenum Cofactor Biosynthesis and Insertion Into Apodinitrogenase by : Priya Rangaraj
Download or read book Studies on the Role of NifH in Iron-molybdenum Cofactor Biosynthesis and Insertion Into Apodinitrogenase written by Priya Rangaraj and published by . This book was released on 1999 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biosynthesis written by F.J. Leeper and published by Springer Science & Business Media. This book was released on 2000-02-14 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concerned with discovering the chemical pathways of biosynthesis, this book devotes four chapters to the use of isotopes in biosynthetic research and the biosynthesis of enzyme cofactors and vitamin B12 and of reduced polyketides such as erythromycin. The topics covered demonstrate the revolution that has occurred in biosynthetic studies with the advent of gene cloning and overexpression. Yet the book also shows that the more classical approach to biosynthetic studies must go hand in hand with these new techniques.
Book Synopsis In Vivo Cofactor Biosynthesis and Maintenance in the Class Ia Ribonucleotide Reductase Small Subunit of Escherichia Coli by : Chia-Hung Wu (Ph. D.)
Download or read book In Vivo Cofactor Biosynthesis and Maintenance in the Class Ia Ribonucleotide Reductase Small Subunit of Escherichia Coli written by Chia-Hung Wu (Ph. D.) and published by . This book was released on 2009 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: The small subunit ([beta]2) of Escherichia coli class Ia ribonucleotide reductases (RNRs) contains a diferric tyrosyl radical (Y*) cofactor essential for the conversion of nucleotides to deoxynucleotides that are needed for DNA synthesis and repair. The mechanism and factors involved in the biosynthesis, maintenance and regulation of this cluster remains unclear. To understand these pathways, the genes contiguous to nrdB (gene encoding [beta]) in 181 bacterial genomes were analyzed which revealed a highly conserved [2Fe2S]-ferredoxin, YfaE in E. coli. YfaE has been cloned, expressed, reconstituted, and characterized by UV-visible, EPR and Mössbauer spectroscopies. Titration of met-[beta]2 (an inactive diferric-[beta]2 with Y* reduced) with [2Fe2S]1+-YfaE results in formation of diferrous-[beta]2 with one Fe reduced/YfaE oxidized. At the end point of titration, exposure of the reduced cluster to O2 in the absence of an additional reducing equivalent yields the diferric-Y* with 2 Fe/Y* generated, suggesting that the reducing equivalent required for cluster assembly is supplied by [beta]2, likely by W48. The kobs for the reaction between met-[beta]2 and [2Fe2S]1+-YfaE determined by anaerobic stopped flow spectroscopy is ~1-5 s-1. Studies of conserved Lys to Ala mutations of [beta]2 indicate electrostatic interactions may play an important role for interaction with YfaE. Quantitative Western blots of the whole cells suggest that YfaE acts catalytically in reactivating met-[beta]2 in vivo. Titration experiments establish that met-[beta]2 can be reduced by catalytic amounts of YfaE, Fre (a flavin reductase) and flavin with consumption of NADPH. In the presence of a Y* scavenger, hydroxyurea, [delta]yfaE shows slower growth rates than the isogenic wt strain and Western blots analysis shows up-regulation of YfaE expression, supporting YfaE's role in the reactivation of diferric-[beta]2 in vivo. To investigate the iron sources for diferric-Y* assembly, changes in Fe pools inside the cell subsequent to expression of [beta]2 was monitored by whole cell Mössbauer spectroscopy. The results show that both Fe2+ and Fe3+ pools can provide the iron for cluster assembly, suggesting a reduction mechanism(s) for Fe3+ to allow it function in this capacity. A potential role of YfaE as an iron chaperone for iron delivery to [beta]2 has also been investigated.
Book Synopsis Metal-Carbon Bonds in Enzymes and Cofactors by : Astrid Sigel
Download or read book Metal-Carbon Bonds in Enzymes and Cofactors written by Astrid Sigel and published by Royal Society of Chemistry. This book was released on 2009-03-09 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapter 10 focuses on the interaction of CN- with enzymes containing vanadium, manganese, non-heme iron, and zinc, and the inhibiting properties of this ligand, allowing its use as a probe. The reaction mechanism of the molybdenum hydroxylase xanthine oxidoreductase is revisited in Chapter 11; previously a molybdenum-carbon bond was postulated but now proof is presented against its formation. The terminating Chapter 12 reviews briefly the most popular computational approaches employed in theoretical studies of bioorganometallic species by providing detailed examples.
Book Synopsis Stereoselective Biocatalysis by : Ramesh N. Patel
Download or read book Stereoselective Biocatalysis written by Ramesh N. Patel and published by CRC Press. This book was released on 2000-01-03 with total page 954 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an explanation of the specific ways that biocatalysis outperforms chemical catalysis by: utilizing ambient temperature and atmospheric pressure to minimize problems of isomerization, racemization, and epimerization; employing microbial cells and enzymes that can be immobilized and reused over many cycles; and overexpressing enzymes for greater economy and efficiency.
Book Synopsis Metals Ions in Biological System by : Astrid Sigel
Download or read book Metals Ions in Biological System written by Astrid Sigel and published by CRC Press. This book was released on 2002-03-06 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 39: Molybdenum and Tungsten: Their Roles in Biological Processes is devoted soley to the vital research area on molybdenum and tungsten and their role in biology. It offers a comprehensive and timely account of this fascinating topic by 40 distinguished international authorities. Topics include: transport, homeostasis, regulation and binding of molybdate and tungstate to proteins, crystallographic characterization, coordination of complexes, and biosynthesis.
Book Synopsis Role of Homocitrate in the Biosynthesis of the Iron-molybdenum Cofactor of Nitrogenase by : Timothy Randall Hoover
Download or read book Role of Homocitrate in the Biosynthesis of the Iron-molybdenum Cofactor of Nitrogenase written by Timothy Randall Hoover and published by . This book was released on 1988 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Sulfur Metabolism in Phototrophic Organisms by : Rüdiger Hell
Download or read book Sulfur Metabolism in Phototrophic Organisms written by Rüdiger Hell and published by Springer Science & Business Media. This book was released on 2008-03-19 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sulfur is one of the most versatile elements in life. This book provides, for the first time, in-depth and integrated coverage of the functions of sulfur in phototrophic organisms including bacteria, plants and algae. It bridges gaps between biochemistry and cellular biology of sulfur in these organisms, and of biology and environments dominated by them. The book therefore provides a comprehensive overview of plant sulfur relations from genome to environment.
Download or read book Biosynthesis written by Finian J. Leeper and published by . This book was released on with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
