Metal-Carbon Bonds in Enzymes and Cofactors

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Author :
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110436582
Total Pages : 532 pages
Book Rating : 4.1/5 (14 download)

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Book Synopsis Metal-Carbon Bonds in Enzymes and Cofactors by : Astrid Sigel

Download or read book Metal-Carbon Bonds in Enzymes and Cofactors written by Astrid Sigel and published by Walter de Gruyter GmbH & Co KG. This book was released on 2015-07-24 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently recognized. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. There is no other comparable book; MILS-6, written by 17 experts, summarizes the most recent insights into this fascinating topic.

Enzymes Dependent on Pyridoxal Phosphate and Other Carbonyl Compounds as Cofactors

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Author :
Publisher : Elsevier
ISBN 13 : 1483287564
Total Pages : 675 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Enzymes Dependent on Pyridoxal Phosphate and Other Carbonyl Compounds as Cofactors by : T. Fukui

Download or read book Enzymes Dependent on Pyridoxal Phosphate and Other Carbonyl Compounds as Cofactors written by T. Fukui and published by Elsevier. This book was released on 2013-10-22 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a summary of the proceedings of the 8th International Symposium on Vitamin B6 and Carbonyl Catalysis, held in Osaka, Japan, 15-19 October 1990. The development of molecular biology and x-ray crystallography techniques have contributed greatly to the knowledge and understanding of PLP-dependent enzymes. The structural, mechanistic and functional aspects of the PLP-dependent enzymes have been studied for over 40 years by many active researchers. Recent evidence indicates that the coenzyme is substituted by the pyruvoyl group which is a reactive carbonyl in some amino acid decarboxylases, and the presence of pyrroloquinoline quinone (PQQ), another carbonyl coenzyme, in other enzymes. The contents of this volume attest to the exciting progress in elucidating structure, mechanism of action, and the function of enzymes dependent on coenzymes containing the carbonyl group.

Inherited Disorders of Vitamins and Cofactors

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9401180199
Total Pages : 162 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Inherited Disorders of Vitamins and Cofactors by : G.M. Addison

Download or read book Inherited Disorders of Vitamins and Cofactors written by G.M. Addison and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the 22nd Annual Symposium of the SSIEM, Newcastle Upon Tyne, September 1984

Molybdenum Cofactors and Their role in the Evolution of Metabolic Pathways

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Author :
Publisher : Springer
ISBN 13 : 9401799725
Total Pages : 79 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Molybdenum Cofactors and Their role in the Evolution of Metabolic Pathways by : Luana Presta

Download or read book Molybdenum Cofactors and Their role in the Evolution of Metabolic Pathways written by Luana Presta and published by Springer. This book was released on 2015-05-07 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this brief, the authors explore and review the current knowledge regarding the role of molybdenum in the evolution of biological systems and their interaction with biogeochemical cycles. Special emphasis is placed on biological nitrogen fixation and the nitrogen element cycle. The origin and evolution of molybdenum cofactor biosynthetic pathways as well as the evolutionary significance of molybdenum containing enzymes appearance is analyzed. Original data regarding nitrogen fixation pathways and related enzymes molecular evolution processes is presented. The trace element molybdenum is essential for nearly all organisms and forms the catalytic center of a large variety of enzymes such as nitrogenase, nitrate reductases, sulphite oxidase and xanthine oxidoreductases.

Novel Cofactors

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Publisher : Gulf Professional Publishing
ISBN 13 : 9780120342587
Total Pages : 502 pages
Book Rating : 4.3/5 (425 download)

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Book Synopsis Novel Cofactors by : Judith P. Klinman

Download or read book Novel Cofactors written by Judith P. Klinman and published by Gulf Professional Publishing. This book was released on 2001-10-05 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cofactor is a component part of many enzymes and functions by uniting with another molecule in order to become active. The use of cofactors to supplement the native amino acids of a protein is essential to maintain the chemical capabilities necessary for organisms to survive. This volume focuses on the significant advances of the past decade in identifying and describing new cofactors--either small molecules or those derived posttranslationally.

Cofactor Biosynthesis: A Mechanistic Perspective

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Author :
Publisher : Academic Press
ISBN 13 : 0080544533
Total Pages : 375 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Cofactor Biosynthesis: A Mechanistic Perspective by :

Download or read book Cofactor Biosynthesis: A Mechanistic Perspective written by and published by Academic Press. This book was released on 2001-01-02 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: The longest running serial published by Academic Press continues its well-respected run with Volume 61, a special volume in which a guest editor has come on board and has assembled some well-known contributors who are international authorities in the field. Together they tackle some of the latest topics in the field such as riboflavin and folate biosynthesis, biotin and lipoic acid biosynthesis, nicotinamide adenine dinucleotide biosynthesis, biosynthesis of vitamin B6 and structurally related derivatives, pantothenic acid and coenzyme A biosynthesis, mechanistic biosynthesis of protein-derived redox cofactors, ascorbic acid biosynthesis, biosynthesis of menaquinone and ubiquinone - Vitamin B12 biosynthesis, biosynthesis of the methanogenic cofactors, and thiamin biosynthesis.

Enzymes in Anesthesiology

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Publisher : Springer Science & Business Media
ISBN 13 : 1461262488
Total Pages : 378 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Enzymes in Anesthesiology by : F. F. Foldes

Download or read book Enzymes in Anesthesiology written by F. F. Foldes and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a pleasure to have the privilege of writing the foreword for a book edited by Dr. Francis F. Foldes. Dr. Foldes has collected in one convenient place a discussion and description of enzyme systems of use to the anesthesiologist and to those other individuals, such as undergraduate and graduate students in related basic sciences, who will profit by and can make use of this body of information. The practicing anesthesiologist and those who work in related fields have become increasingly aware of the need to understand enzyme activities which influence the uptake, distribution, and excretion of those substances that are used in the anesthetic management of surgical patients. A variety of such is obvious when one considers that such diverse substances as activities and muscle re analgesic drugs, tranquilizers, hypnotics, anesthetic agents, laxants are strongly affected by these systems and have an influence over the basic understanding of how these drugs operate and act in the body, as well as providing a safety measure so necessary to the proper conduct of clinical anesthesia. The editor and his colleagues have rendered us a great service in collecting information that deals with the basic activity of enzymes including their structure, their kinetics, and to the degree that knowledge permits, mechanism of actions.

Comprehensive Natural Products III

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Author :
Publisher : Elsevier
ISBN 13 : 0081026919
Total Pages : 4266 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Comprehensive Natural Products III by :

Download or read book Comprehensive Natural Products III written by and published by Elsevier. This book was released on 2020-07-22 with total page 4266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Natural Products III, Third Edition, Seven Volume Set updates and complements the previous two editions, including recent advances in cofactor chemistry, structural diversity of natural products and secondary metabolites, enzymes and enzyme mechanisms and new bioinformatics tools. Natural products research is a dynamic discipline at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids and enzymes. This book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community. Provides readers with an in-depth review of current natural products research and a critical insight into the future direction of the field Bridges the gap in knowledge by covering developments in the field since the second edition published in 2010 Split into 7 sections on key topics to allow students, researchers and professionals to find relevant information quickly and easily Ensures that the knowledge within is easily understood by and applicable to a large audience

Encyclopedia of Food and Health

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Author :
Publisher : Academic Press
ISBN 13 : 0123849535
Total Pages : 2379 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Encyclopedia of Food and Health by :

Download or read book Encyclopedia of Food and Health written by and published by Academic Press. This book was released on 2015-08-26 with total page 2379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approx.3876 pages Approx.3876 pages

Fundamentals of Enzyme Engineering

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Author :
Publisher : Springer
ISBN 13 : 9402410260
Total Pages : 208 pages
Book Rating : 4.4/5 (24 download)

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Book Synopsis Fundamentals of Enzyme Engineering by : Young Je Yoo

Download or read book Fundamentals of Enzyme Engineering written by Young Je Yoo and published by Springer. This book was released on 2017-01-12 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive introduction to all aspects of enzyme engineering, from fundamental principles through to the state-of-the-art in research and industrial applications. It begins with a brief history, describing the milestones of advancement in enzyme science and technology, before going on to cover the fundamentals of enzyme chemistry, the biosynthesis of enzymes and their production. Enzyme stability and the reaction kinetics during enzymatic reactions are presented to show how enzymes function during catalysis and the factors that affect their activity. Methods to improve enzyme performance are also presented, such as cofactor regeneration and enzyme immobilization. The book emphasizes and elaborates on the performance and characteristics of enzymes at the molecular level. Finally, the book presents recent advances in enzyme engineering and some key industrial application of enzymes addressing the present needs of society. This book presents essential information not only for undergraduate and graduate students, but also for researchers in academia and industry, providing a valuable reference for the development of commercial applications of enzyme technology.

Prions and Diseases

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461453054
Total Pages : 246 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Prions and Diseases by : Wen-Quan Zou

Download or read book Prions and Diseases written by Wen-Quan Zou and published by Springer Science & Business Media. This book was released on 2012-11-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume I highlights the association of the cellular prion protein (PrPC) with copper and zinc, the potential roles of PrPC in Alzheimer’s disease and cancers, insoluble PrPC, PMCA, molecular and cellular mechanisms of PrPSc formation and clearance, possible co-factors involved in the conversion of PrPC into PrPSc, infectious and pathogenic forms of PrP, cell biology of prions, prion strains and their interference, as well as yeast prions and their inheritable and structural traits. This unique volume will take you through the fascinating chronicle of prions in mammals, yeast, and fungi.

Artificial Metalloenzymes and MetalloDNAzymes in Catalysis

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527341781
Total Pages : 428 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Artificial Metalloenzymes and MetalloDNAzymes in Catalysis by : Montserrat Diéguez

Download or read book Artificial Metalloenzymes and MetalloDNAzymes in Catalysis written by Montserrat Diéguez and published by John Wiley & Sons. This book was released on 2018-06-05 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important reference for researchers in the field of metal-enzyme hybrid catalysis Artificial Metalloenzymes and MetalloDNAzymes in Catalysis offers a comprehensive review of the most current strategies, developed over recent decades, for the design, synthesis, and optimization of these hybrid catalysts as well as material about their application. The contributors—noted experts in the field—present information on the preparation, characterization, and optimization of artificial metalloenzymes in a timely and authoritative manner. The authors present a thorough examination of this interesting new platform for catalysis that combines the excellent selective recognition/binding properties of enzymes with transition metal catalysts. The text includes information on the various applications of metal-enzyme hybrid catalysts for novel reactions, offers insights into the latest advances in the field, and contains an informative perspective on the future: Explores the development of artificial metalloenzymes, the modern and strongly evolving research field on the verge of industrial application Contains a comprehensive reference to the research area of metal-enzyme hybrid catalysis that has experienced tremendous growth in recent years Includes contributions from leading researchers in the field Shows how this new catalysis combines the selective recognition/binding properties of enzymes with transition metal catalysts Written for catalytic chemists, bioinorganic chemists, biochemists, and organic chemists, Artificial Metalloenzymes and MetalloDNAzymes in Catalysis offers a unique reference to the fundamentals, concepts, applications, and the most recent developments for more efficient and sustainable synthesis.

Separation Methods In Proteomics

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Author :
Publisher : CRC Press
ISBN 13 : 1420028057
Total Pages : 532 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Separation Methods In Proteomics by : Gary B. Smejkal

Download or read book Separation Methods In Proteomics written by Gary B. Smejkal and published by CRC Press. This book was released on 2005-12-12 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Driven by the widespread growth of proteomic practices, protein separation techniques have been refined to minimize variability, optimize particular applications, and adapt to user preferences in the analysis of proteins. Separation Methods in Proteomics provides a comprehensive examination of all major separation techniques for proteomic

MCAT Biochemistry Review 2018-2019

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Author :
Publisher : Simon and Schuster
ISBN 13 : 1506223753
Total Pages : 513 pages
Book Rating : 4.5/5 (62 download)

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Book Synopsis MCAT Biochemistry Review 2018-2019 by : Kaplan Test Prep

Download or read book MCAT Biochemistry Review 2018-2019 written by Kaplan Test Prep and published by Simon and Schuster. This book was released on 2017-07-04 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kaplan's MCAT Biochemistry Review 2018-2019 offers an expert study plan, detailed subject review, and hundreds of online and in-book practice questions – all authored by the experts behind the MCAT prep course that has helped more people get into medical school than all other major courses combined. Prepping for the MCAT is a true challenge. Kaplan can be your partner along the way – offering guidance on where to focus your efforts and how to organize your review. With the most recent changes to the MCAT, biochemistry is one of the most high-yield areas for study. This book has been updated to match the AAMC's guidelines precisely—no more worrying if your MCAT review is comprehensive! The Most Practice More than 350 questions in the book and access to even more online – more practice than any other MCAT biochemistry book on the market. The Best Practice Comprehensive biochemistry subject review is written by top-rated, award-winning Kaplan instructors. Full-color, 3-D illustrations from Scientific American, charts, graphs and diagrams help turn even the most complex science into easy-to-visualize concepts. All material is vetted by editors with advanced science degrees and by a medical doctor. Online resources help you practice in the same computer-based format you'll see on Test Day. Expert Guidance High-yield badges throughout the book identify the top 100 topics most-tested by the AAMC. We know the test: The Kaplan MCAT team has spent years studying every MCAT-related document available. Kaplan's expert psychometricians ensure our practice questions and study materials are true to the test.

Matrix Operations for Engineers and Scientists

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9048192749
Total Pages : 323 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Matrix Operations for Engineers and Scientists by : Alan Jeffrey

Download or read book Matrix Operations for Engineers and Scientists written by Alan Jeffrey and published by Springer Science & Business Media. This book was released on 2010-09-05 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Engineers and scientists need to have an introduction to the basics of linear algebra in a context they understand. Computer algebra systems make the manipulation of matrices and the determination of their properties a simple matter, and in practical applications such software is often essential. However, using this tool when learning about matrices, without first gaining a proper understanding of the underlying theory, limits the ability to use matrices and to apply them to new problems. This book explains matrices in the detail required by engineering or science students, and it discusses linear systems of ordinary differential equations. These students require a straightforward introduction to linear algebra illustrated by applications to which they can relate. It caters of the needs of undergraduate engineers in all disciplines, and provides considerable detail where it is likely to be helpful. According to the author the best way to understand the theory of matrices is by working simple exercises designed to emphasize the theory, that at the same time avoid distractions caused by unnecessary numerical calculations. Hence, examples and exercises in this book have been constructed in such a way that wherever calculations are necessary they are straightforward. For example, when a characteristic equation occurs, its roots (the eigenvalues of a matrix) can be found by inspection. The author of this book is Alan Jeffrey, Emeritus Professor of mathematics at the University of Newcastle upon Tyne. He has given courses on engineering mathematics at UK and US Universities.

Systems biology and ecology of microbial mat communities

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 288919793X
Total Pages : 264 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Systems biology and ecology of microbial mat communities by : Martin G. Klotz

Download or read book Systems biology and ecology of microbial mat communities written by Martin G. Klotz and published by Frontiers Media SA. This book was released on 2016-04-11 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial mat communities consist of dense populations of microorganisms embedded in exopolymers and/or biomineralized solid phases, and are often found in mm-cm thick assemblages, which can be stratified due to environmental gradients such as light, oxygen or sulfide. Microbial mat communities are commonly observed under extreme environmental conditions, deriving energy primarily from light and/or reduced chemicals to drive autotrophic fixation of carbon dioxide. Microbial mat ecosystems are regarded as living analogues of primordial systems on Earth, and they often form perennial structures with conspicuous stratifications of microbial populations that can be studied in situ under stable conditions for many years. Consequently, microbial mat communities are ideal natural laboratories and represent excellent model systems for studying microbial community structure and function, microbial dynamics and interactions, and discovery of new microorganisms with novel metabolic pathways potentially useful in future industrial and/or medical applications. Due to their relative simplicity and organization, microbial mat communities are often excellent testing grounds for new technologies in microbiology including micro-sensor analysis, stable isotope methodology and modern genomics. Integrative studies of microbial mat communities that combine modern biogeochemical and molecular biological methods with traditional microbiology, macro-ecological approaches, and community network modeling will provide new and detailed insights regarding the systems biology of microbial mats and the complex interplay among individual populations and their physicochemical environment. These processes ultimately control the biogeochemical cycling of energy and/or nutrients in microbial systems. Similarities in microbial community function across different types of communities from highly disparate environments may provide a deeper basis for understanding microbial community dynamics and the ecological role of specific microbial populations. Approaches and concepts developed in highly-constrained, relatively stable natural communities may also provide insights useful for studying and understanding more complex microbial communities.

Cancer Chemoprevention

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 159259767X
Total Pages : 998 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Cancer Chemoprevention by : Gary J. Kelloff

Download or read book Cancer Chemoprevention written by Gary J. Kelloff and published by Springer Science & Business Media. This book was released on 2004-06-04 with total page 998 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accompanying CD-ROM in pocket at end of v. 2 contains a compact e-book version of v. 2.