Clinical Trials In Ovarian Cancer

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Clinical Trials in Ovarian Cancer

Author : Christine S. Walsh
Publisher : Rutgers University Press
ISBN 13 : 0813586496
Total Pages : 337 pages
Book Rating : 4.8/5 (135 download)

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Book Synopsis Clinical Trials in Ovarian Cancer by : Christine S. Walsh

Download or read book Clinical Trials in Ovarian Cancer written by Christine S. Walsh and published by Rutgers University Press. This book was released on 2017-01-16 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: When a patient is diagnosed with a gynecological malignancy, she and her doctors must make urgent, high-risk decisions about her course of treatment. In selecting an appropriate plan of care, physicians must weigh the patient’s individual needs, the tumor’s specific characteristics, and the treatment’s potential side effects. Because there is no one-size-fits-all treatment solution, a plethora of clinical trials have been performed on ovarian cancer patients, but clinicians may struggle to keep up with this ever-growing body of research. Collecting and synthesizing research findings from a wide array of medical journal articles and book chapters, Clinical Trials in Ovarian Cancer provides physicians with an invaluable resource. Gynecologic oncologist Christine S. Walsh systematically outlines each of the seminal Phase III trials that have shaped the treatment of ovarian cancers, detailing the rationale for the trial, the patient population studied, treatment delivery methods, efficacy, toxicity, and trial conclusions. She provides a clear overview of established treatments, as well as still-controversial experimental approaches. The first book to organize this cutting-edge research into an easy-to-use reference, Clinical Trials in Ovarian Cancer should help medical personnel at all levels provide their patients with the highest standard of care.

Synopsis of Key Gynecologic Oncology Trials

Author : Malte Renz
Publisher : CRC Press
ISBN 13 : 1000783642
Total Pages : 222 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Synopsis of Key Gynecologic Oncology Trials by : Malte Renz

Download or read book Synopsis of Key Gynecologic Oncology Trials written by Malte Renz and published by CRC Press. This book was released on 2022-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised and updated new edition of a best-selling text remains a fast and convenient overview of the clinical trials in gynecologic cancer treatment, outlining the evidence base of treatment decisions in uterine, ovarian, cervical, and vulvar cancers, and gestational trophoblastic neoplasia. Residents and fellows will find this book an indispensable reference, while practitioners will welcome it as a clarification of the evidence base for treatment options. *Gives a convenient summary of trials in gynecologic oncology *Supplies an invaluable revision primer for those undertaking certification *Provides a uniquely up-to-date resource

Clinical Gynecology

Author : Eric J. Bieber
Publisher : Cambridge University Press
ISBN 13 : 1107040396
Total Pages : 1127 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Clinical Gynecology by : Eric J. Bieber

Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

Chemosensitivity Testing in Oncology

Author : Uwe Reinhold
Publisher : Springer Science & Business Media
ISBN 13 : 9783540434689
Total Pages : 262 pages
Book Rating : 4.4/5 (346 download)

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Book Synopsis Chemosensitivity Testing in Oncology by : Uwe Reinhold

Download or read book Chemosensitivity Testing in Oncology written by Uwe Reinhold and published by Springer Science & Business Media. This book was released on 2002-10-31 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 50 years many in vitro and in vivo drug response assay systems have been developed to determine the potential - tivity of chemotherapy agents. The idea was to eliminate ineffective agents and unnecessary toxic treatment while selecting drugs active in vitro or in the mouse model that might increase the probability of response in the patient. None of these test models, however, achieved routine clinical application in the past. This might be at least in part - lated to large discrepancies that were described between the s- cess rate of the assay systems and the clinical benefit in cancer - tients. The heterogeneity of chemosensitivity that exists between different tumors as well as between individual tumor lesions may be one explanation for these findings. Furthermore, different assay end points such as proliferation, metabolism, and vitality were - veloped to evaluate the effects of cytostatic drugs on tumor cells, and these might be related to the differing results. However, knowledge about procedures for assay-assisted treatment selection has increased rapidly within the past few years, and several studies suggest that test-directed chemotherapy selection now may - prove response rates and survival in various types of tumors. The International Society for Chemosensitivity Testing in - cology (ISCO) was founded to promote, coordinate, and improve clinical and laboratory research in the field of predictive drug te- ing in human tumor cells.

Surgery for Ovarian Cancer

Author : Robert E. Bristow
Publisher : CRC Press
ISBN 13 : 0429578857
Total Pages : 437 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Surgery for Ovarian Cancer by : Robert E. Bristow

Download or read book Surgery for Ovarian Cancer written by Robert E. Bristow and published by CRC Press. This book was released on 2019-02-21 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated and expanded, the third edition of Surgery for Ovarian Cancer focuses on essential techniques for the effective management of ovarian cancer. It reflects the most contemporary science and surgical applications for the management of patients with ovarian cancer and related peritoneal surface malignancies. This new edition takes a step-by-step approach and includes new intraoperative photographs and videos illustrating surgical procedures. It is principally devoted to the technical aspects of cytoreductive surgery, with chapters divided according to anatomic region. The chapters cover relevant anatomical considerations, surgical challenges specific to each region, and operative approaches and techniques favored by the authors. The list of contributing authors has been expanded from the previous edition and includes international and world-renowned experts from the fields of gynecologic oncology and surgical oncology. The topics of minimally invasive surgery, secondary cytoreduction, palliative surgery, and postoperative care are also covered in detail. New to the third edition are chapters on preoperative risk stratification, regional therapeutics and peritonectomy procedures, and quality assurance relating to ovarian cancer surgery. This comprehensive text is essential reading for all practitioners working with patients with ovarian cancers.

Ovarian Cancer

Author : George Coukos
Publisher : Springer Science & Business Media
ISBN 13 : 0387689699
Total Pages : 299 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Ovarian Cancer by : George Coukos

Download or read book Ovarian Cancer written by George Coukos and published by Springer Science & Business Media. This book was released on 2008-06-06 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aegean Conferences is an independent, nonprofit, educational organization directed and managed by the scientific community. The board is made up of nine researchers/scientists in various disciplines from Harvard, Brown, University of Pennsylvania, UCSD, Princeton, Biovista and the Foundation for Biomedical Research Academy of Athens. The board both invites and approves unsolicited proposals for Conferences in all fields of Science, Engineering, Arts, and Humanities. The purpose of the Conferences is to bring together individuals with common interests to examine the emerging and most advanced aspects of their particular field. The Symposium on Ovarian Cancer: State of the Art and Future Directions intends to bring together international experts interested in the development of novel diagnostic, prognostic and therapeutic tools for ovarian cancer. The meeting will function as a think tank where clinicians, translational and basic scientists, and parties from the biotechnology and pharmaceutical industry will get together to review recent advances in clinical research and translational science in ovarian cancer and define areas of future research opportunities and priorities.

Ovarian Cancers

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309380464
Total Pages : 397 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Ovarian Cancers by : National Academies of Sciences, Engineering, and Medicine

Download or read book Ovarian Cancers written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-05-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: In an era of promising advances in cancer research, there are considerable and even alarming gaps in the fundamental knowledge and understanding of ovarian cancer. Researchers now know that ovarian cancer is not a single disease-several distinct subtypes exist with different origins, risk factors, genetic mutations, biological behaviors, and prognoses. However, persistent questions have impeded progress toward improving the prevention, early detection, treatment, and management of ovarian cancers. Failure to significantly improve morbidity and mortality during the past several decades is likely due to several factors, including the lack of research being performed by specific disease subtype, lack of definitive knowledge of the cell of origin and disease progression, and incomplete understanding of genetic and non-genetic risk factors. Ovarian Cancers examines the state of the science in ovarian cancer research, identifies key gaps in the evidence base and the challenges to addressing those gaps, considers opportunities for advancing ovarian cancer research, and examines avenues for translation and dissemination of new findings and communication of new information to patients and others. This study makes recommendations for public- and private-sector efforts that could facilitate progress in reducing the incidence of morbidity and mortality from ovarian cancers.

Ovarian Cancers

Author : Eric Pujade-Lauraine
Publisher : Springer
ISBN 13 : 3319321102
Total Pages : 286 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Ovarian Cancers by : Eric Pujade-Lauraine

Download or read book Ovarian Cancers written by Eric Pujade-Lauraine and published by Springer. This book was released on 2016-10-17 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the latest developments in the concepts and management of ovarian cancer. The new data presented throughout opens the way to radically different therapeutic approaches. Surgery remains the core of ovarian cancer treatment, but its ultimate goal and the standard surgical procedure have evolved, giving rise to the question of how to label expert centers for debulking surgery. Neo-adjuvant chemotherapy is becoming more popular and is also a new field for testing novel drug combinations. Over recent years, ovarian cancer management has embraced molecular biology. It is now more correct to talk about cancers of the ovary rather than ovarian cancer, since it is not a unique disease but several entities with different molecular drivers. The significant advances in drugs targeting the microenvironment or the tumor cell DNA repair mechanisms are presented in detail together with exciting future perspectives. All these advances would not have been possible without collaborative groups such as the GINECO group in France and their integration in wider clinical research networks at the European (ENGOT) and international (GCIG) level.

Overcoming Ovarian Cancer Chemoresistance

Author : Goli Samimi
Publisher : Academic Press
ISBN 13 : 0128198419
Total Pages : 190 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Overcoming Ovarian Cancer Chemoresistance by : Goli Samimi

Download or read book Overcoming Ovarian Cancer Chemoresistance written by Goli Samimi and published by Academic Press. This book was released on 2020-11-06 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overcoming Ovarian Cancer Chemoresistance presents non-overlapping review chapters that discuss the state of the field in overcoming chemoresistance of ovarian cancer and treatment options before and following recurrence, considering the genetic makeup of the ovarian cancer patient and her tumor. With the uptake of both germline and somatic gene testing, clinicians can obtain a more comprehensive understanding of ovarian tumors and this book provides information to link the genetic makeup of a tumor (or patient) with the best available treatment. The book discusses topics such as strategies to fight chemo-resistance in ovarian cancer, circulating DNA as a monitor of response, BRCA mutations, ovarian cancer stem cells, immunotherapy and vaccines. Additionally, it brings a list of promising agents at clinical and pre-clinical stage that will impact the treatment in the near future. This book is a valuable source for cancer researchers, oncologists and several members of biomedical field who need to understand how to battle chemoresistance in ovarian cancer. Provides a comprehensive view of both biological and genetic determinants of resistance, as well as technical approaches to monitor response Discusses genetic reversions as a unique alteration and a new field of study Includes a chapter on upcoming and promising agents that are in the pre-clinical and early clinical space, to set the stage for future directions in the field

Clinical Trials in Oncology, Third Edition

Author : Stephanie Green
Publisher : CRC Press
ISBN 13 : 1439814481
Total Pages : 266 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Clinical Trials in Oncology, Third Edition by : Stephanie Green

Download or read book Clinical Trials in Oncology, Third Edition written by Stephanie Green and published by CRC Press. This book was released on 2012-05-09 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data. Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.

Gynecologic Oncology Clinical Trials Review

Author : Rebecca Phaeton
Publisher :
ISBN 13 : 9781980284222
Total Pages : 129 pages
Book Rating : 4.2/5 (842 download)

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Book Synopsis Gynecologic Oncology Clinical Trials Review by : Rebecca Phaeton

Download or read book Gynecologic Oncology Clinical Trials Review written by Rebecca Phaeton and published by . This book was released on 2018-02-13 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gynecologic Oncology Clinical Trials Review: Landmark Studies in Uterine Cancer represents a comprehensive review and synopsis of pivotal trials in uterine cancer. It is designed for ease of use and ready comprehension, with its topics divided into disease stages and studies in chronological order. Its reader-friendly format, condensation of entire clinical trials into salient highlights, discussion of limitations, areas of controversy and the clinical impact of the trial provides a succinct yet detailed synopsis of important studies. This Gynecologic Oncology Clinical Trials Book aims to serve as an indispensable resource for gynecologic oncologists, medical oncologists, and radiation oncologists, fellows and residents, as well as a study resource and reference.Gynecologic Oncology Clinical Trials Review: Landmark Studies in Uterine Cancer represents the first installment, with subsequent releases of ovarian cancer, cervix cancer, and vulvar cancer planned.

The 21st Century Handbook of Clinical Ovarian Cancer

Author : Krishnansu S Tewari
Publisher : Springer
ISBN 13 : 3319080660
Total Pages : 200 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis The 21st Century Handbook of Clinical Ovarian Cancer by : Krishnansu S Tewari

Download or read book The 21st Century Handbook of Clinical Ovarian Cancer written by Krishnansu S Tewari and published by Springer. This book was released on 2015-01-13 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough review on ovarian cancer, treatment guidelines and emerging therapies available for the disease. The book was originally commissioned due to recent developments in therapies for ovarian cancer. This concise pocket book will review ovarian cancer’s epidemiology, clinical features, diagnosis and medical management. Busy healthcare professionals will benefit from this text, which will not only cover the foundation of ovarian cancer management, but discuss up-to-date national and international treatment guidelines and upcoming therapies.

Emerging Therapeutic Targets in Ovarian Cancer

Author : Stan Kaye
Publisher : Springer Science & Business Media
ISBN 13 : 1441972161
Total Pages : 291 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Emerging Therapeutic Targets in Ovarian Cancer by : Stan Kaye

Download or read book Emerging Therapeutic Targets in Ovarian Cancer written by Stan Kaye and published by Springer Science & Business Media. This book was released on 2010-11-23 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ovarian Cancer

Author : Ivan Diaz-Padilla
Publisher : BoD – Books on Demand
ISBN 13 : 9535110306
Total Pages : 386 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Ovarian Cancer by : Ivan Diaz-Padilla

Download or read book Ovarian Cancer written by Ivan Diaz-Padilla and published by BoD – Books on Demand. This book was released on 2013-02-27 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Ovarian Cancer: A Clinical and Translational Update" embraces the most recent advances in diagnosis and treatment of ovarian cancer. With the valuable collaboration of international experts in the field, this book is intended to provide the readership with a comprehensive update in the subject of epithelial ovarian cancer.

Ovarian Cancer - Challenges & Innovations

Author : Tamara L. Kalir
Publisher : Bentham Science Publishers
ISBN 13 : 9789811421853
Total Pages : 222 pages
Book Rating : 4.4/5 (218 download)

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Book Synopsis Ovarian Cancer - Challenges & Innovations by : Tamara L. Kalir

Download or read book Ovarian Cancer - Challenges & Innovations written by Tamara L. Kalir and published by Bentham Science Publishers. This book was released on 2019-11-05 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This informative book provides a wealth of information on ovarian cancer. The book opens with a discussion of contemporary management of this disease with commentary on surgery and clinical trials: neoadjuvant, dose-dense, and heated intraperitoneal chemotherapy (HIPEC}, as well as immunotherapy, vaccine therapy, emerging therapies. This is followed by presentations on ovarian cancer pathology. A chapter is devoted to methods of drug discovery through a functional genomics approach, with gene expression microarray databases available in public data repositories such as Public Gene Expression Omnibus (GEO} and validation using immunohistochemistry or Ingenuity Pathway Analysis (IPA). Next, the book explores the psycho-social issues that may be encountered by an ovarian cancer patient, including commentary on pain, fertility, anxiety, depression, demoralization, caregiver burnout, and end-of-life. The final chapter represents a step out from mainstream medical practice and provides an exposition of the mind-body interaction and the powerful role of belief in the healing process, with discussions of the placebo effect, nocebo effect, and numerous research studies that demonstrate the tremendous influence of our beliefs on our bodies and well-being.Key Features: Provides a holistic view of ovarian cancer.Covers both conventional medical research topics and key social issues encountered by patients, caregivers and medical professionals.Explains cancer pathology and related concepts with the help of illustrations and notes on future directions.Features commentary from experts in ovarian cancer treatment.Written in a reader-friendly style suitable for a wide range of readersOvarian Cancer - Challenges and Innovations is a comprehensive reference about ovarian cancer for medical students, residents, practitioners, healthcare support staff (nurses, physician assistants), medical researchers and scientists, as well as patients and interested laypersons seeking to improve their current knowledge of ovarian cancer

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2008 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Diagnosis and Management of Ovarian Disorders

Author : Albert Altchek
Publisher : Elsevier
ISBN 13 : 008049451X
Total Pages : 568 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Diagnosis and Management of Ovarian Disorders by : Albert Altchek

Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES * Includes updated information on early diagnosis of ovarian cancer * Reviews new diagnostic techniques for ovarian disorders * Discusses latest information on reproductive technology * Presents translational treatment linking laboratory research with clinical medicine