Clinical Application of Stereotactic Body Radiotherapy (SBRT): Cranium to Prostate

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Publisher : Frontiers Media SA
ISBN 13 : 2889198464
Total Pages : 87 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Clinical Application of Stereotactic Body Radiotherapy (SBRT): Cranium to Prostate by : Dwight E. Heron

Download or read book Clinical Application of Stereotactic Body Radiotherapy (SBRT): Cranium to Prostate written by Dwight E. Heron and published by Frontiers Media SA. This book was released on 2016-06-21 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic radiosurgery is a relatively recent radiation technique initially developed using a frame-based system in 1949 by a Swedish neurosurgeon, Lars Leksell, for lesions not amendable to surgical resection. Radiosurgery is founded on principles of extreme radiation dose escalation, afforded by precise dose delivery with millimeter accuracy. Building upon the success of frame-based radiosurgery techniques, which were limited to cranial tumors and invasive head-frame placement, advances in radiation delivery and image-guidance have lead to the development of stereotactic body radiotherapy (SBRT). SBRT allows for frameless delivery of dose distributions akin to frame-based cranial stereotactic radiosurgery to both cranial and extra-cranial sites and has emerged as a important treatment strategy for a variety of cancers from the cranium to prostate. Herein we highlight ongoing investigations for the clinical application of SBRT for a variety of primary and recurrence cancers aimed at examining the growing clinical evidence supporting emerging roles for SBRT in the ever growing oncologic armamentarium.

Clinical Application of Stereotactic Body Radiotherapy (SBRT): Cranium to Prostate

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Clinical Application of Stereotactic Body Radiotherapy (SBRT): Cranium to Prostate by :

Download or read book Clinical Application of Stereotactic Body Radiotherapy (SBRT): Cranium to Prostate written by and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic radiosurgery is a relatively recent radiation technique initially developed using a frame-based system in 1949 by a Swedish neurosurgeon, Lars Leksell, for lesions not amendable to surgical resection. Radiosurgery is founded on principles of extreme radiation dose escalation, afforded by precise dose delivery with millimeter accuracy. Building upon the success of frame-based radiosurgery techniques, which were limited to cranial tumors and invasive head-frame placement, advances in radiation delivery and image-guidance have lead to the development of stereotactic body radiotherapy (SBRT). SBRT allows for frameless delivery of dose distributions akin to frame-based cranial stereotactic radiosurgery to both cranial and extra-cranial sites and has emerged as a important treatment strategy for a variety of cancers from the cranium to prostate. Herein we highlight ongoing investigations for the clinical application of SBRT for a variety of primary and recurrence cancers aimed at examining the growing clinical evidence supporting emerging roles for SBRT in the ever growing oncologic armamentarium.

Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy (SBRT)

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Author :
Publisher : Springer Publishing Company
ISBN 13 : 0826168574
Total Pages : 600 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy (SBRT) by : Dwight E. Heron, MD, MBA, FACRO, FACR

Download or read book Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy (SBRT) written by Dwight E. Heron, MD, MBA, FACRO, FACR and published by Springer Publishing Company. This book was released on 2018-09-28 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy (SBRT) is a comprehensive guide for the practicing physician and medical physicist in the management of complex intracranial and extracranial disease. It is a state-of-the-science book presenting the scientific principles, clinical background and procedures, treatment planning, and treatment delivery of SRS and SBRT for the treatment of tumors throughout the body. This unique textbook is enhanced with supplemental video tutorials inclusive to the resource. Beginning with an overview of SRS and SBRT, Part I contains insightful coverage on topics such as the evolving radiobiological principles that govern treatment, imaging, the treatment planning process, technologies and equipment used, as well as focused chapters on quality assurance, quality management, and patient safety. Part II contains the clinical application of SRS and SBRT for tumors throughout the body including those in the brain, head and neck, lung, pancreas, adrenal glands, liver, prostate, cervix, spine, and in oligometastatic disease. Each clinical chapter includes an introduction to the disease site, followed by a thorough review of all indications and exclusion criteria, in addition to the important considerations for patient selection, treatment planning and delivery, and outcome evaluation. These chapters conclude with a detailed and site-specific dose constraints table for critical structures and their suggested dose limits. International experts on the science and clinical applications of these treatments have joined together to assemble this must-have book for clinicians, physicists, and other radiation therapy practitioners. It provides a team-based approach to SRS and SBRT coupled with case-based video tutorials in disease management, making this a unique companion for the busy radiosurgical team. Key Features: Highlights the principles of radiobiology and radiation physics underlying SRS and SBRT Presents and discusses the expected patient outcomes for each indicated disease site and condition including a detailed analysis of Quality of Life (QOL) and Survival Includes information about technologies used for the treatment of SRS and SBRT Richly illustrated with over 110 color images of the equipment, process flow diagrams and procedures, treatment planning techniques and dose distributions 7 high-quality videos reviewing anatomy, staging, treatment simulation and planning, contouring, and management pearls Dose constraint tables at the end of each clinical chapter listing critical structures and their appropriate dose limits Includes access to the fully-searchable downloadable eBook

Stereotactic Body Radiation Therapy

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 364225604X
Total Pages : 433 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Stereotactic Body Radiation Therapy by : Simon S. Lo

Download or read book Stereotactic Body Radiation Therapy written by Simon S. Lo and published by Springer Science & Business Media. This book was released on 2012-08-28 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.

Novel Applications of Stereotactic Body Radiation Therapy (SBRT)

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889715183
Total Pages : 100 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Novel Applications of Stereotactic Body Radiation Therapy (SBRT) by : Debnarayan Dutta

Download or read book Novel Applications of Stereotactic Body Radiation Therapy (SBRT) written by Debnarayan Dutta and published by Frontiers Media SA. This book was released on 2021-10-21 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stereotactic Body Radiation Therapy

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642256058
Total Pages : 434 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Stereotactic Body Radiation Therapy by : Simon S. Lo

Download or read book Stereotactic Body Radiation Therapy written by Simon S. Lo and published by Springer Science & Business Media. This book was released on 2012-08-28 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.

Stereotactic Body Radiotherapy for Prostate Cancer

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832506461
Total Pages : 129 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Stereotactic Body Radiotherapy for Prostate Cancer by : Amar U. Kishan

Download or read book Stereotactic Body Radiotherapy for Prostate Cancer written by Amar U. Kishan and published by Frontiers Media SA. This book was released on 2022-11-18 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy

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Author :
Publisher : Springer Nature
ISBN 13 : 3031331567
Total Pages : 303 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy by : Rajni A. Sethi

Download or read book Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy written by Rajni A. Sethi and published by Springer Nature. This book was released on 2023-10-01 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook concisely summarizes state-of-the-art information about stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), including the history and development of these modalities, the biologic rationale for these technologies, typical practices, and reported results. Developed as a companion to Handbook of Evidence-Based Radiation Oncology, edited by Eric Hansen and Mack Roach, III, it is organized by disease site and presents treatment techniques and recommended imaging; safety and quality assurance; toxicities and management; recommended follow-up; and supporting evidence. Inclusion of evidence-based guidelines is intended to help inform decisions regarding the appropriateness of SRS and SBRT and guide treatment and evaluation. This new edition is fully updated with the latest literature. A new chapter on dose constraints has also been added, along with additional content on SBRT for oligometastatic disease and prostate, and the integration of SBRT with systemic therapy, including chemotherapy, immunotherapy, targeted agents. Case examples are added, as well as additional images to highlight situations described. Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy, 2e can be easily referenced in the clinic and is a valuable guide for radiation oncology practitioners

Stereotactic Body Radiotherapy

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Publisher : Springer
ISBN 13 : 0857295977
Total Pages : 336 pages
Book Rating : 4.8/5 (572 download)

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Book Synopsis Stereotactic Body Radiotherapy by : Andrew Gaya

Download or read book Stereotactic Body Radiotherapy written by Andrew Gaya and published by Springer. This book was released on 2015-01-24 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a single, comprehensive handbook for clinical oncology trainees and consultants, covering the basic aspects of stereotactic radiotherapy systems and treatment.

Surface Guided Radiation Therapy

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Publisher : CRC Press
ISBN 13 : 0429951809
Total Pages : 515 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Surface Guided Radiation Therapy by : Jeremy David Page Hoisak

Download or read book Surface Guided Radiation Therapy written by Jeremy David Page Hoisak and published by CRC Press. This book was released on 2020-02-13 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface Guided Radiation Therapy provides a comprehensive overview of optical surface image guidance systems for radiation therapy. It serves as an introductory teaching resource for students and trainees, and a valuable reference for medical physicists, physicians, radiation therapists, and administrators who wish to incorporate surface guided radiation therapy (SGRT) into their clinical practice. This is the first book dedicated to the principles and practice of SGRT, featuring: Chapters authored by an internationally represented list of physicists, radiation oncologists and therapists, edited by pioneers and experts in SGRT Covering the evolution of localization systems and their role in quality and safety, current SGRT systems, practical guides to commissioning and quality assurance, clinical applications by anatomic site, and emerging topics including skin mark-less setups. Several dedicated chapters on SGRT for intracranial radiosurgery and breast, covering technical aspects, risk assessment and outcomes. Jeremy Hoisak, PhD, DABR is an Assistant Professor in the Department of Radiation Medicine and Applied Sciences at the University of California, San Diego. Dr. Hoisak’s clinical expertise includes radiosurgery and respiratory motion management. Adam Paxton, PhD, DABR is an Assistant Professor in the Department of Radiation Oncology at the University of Utah. Dr. Paxton’s clinical expertise includes patient safety, motion management, radiosurgery, and proton therapy. Benjamin Waghorn, PhD, DABR is the Director of Clinical Physics at Vision RT. Dr. Waghorn’s research interests include intensity modulated radiation therapy, motion management, and surface image guidance systems. Todd Pawlicki, PhD, DABR, FAAPM, FASTRO, is Professor and Vice-Chair for Medical Physics in the Department of Radiation Medicine and Applied Sciences at the University of California, San Diego. Dr. Pawlicki has published extensively on quality and safety in radiation therapy. He has served on the Board of Directors for the American Society for Radiology Oncology (ASTRO) and the American Association of Physicists in Medicine (AAPM).

Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy

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Author :
Publisher : Springer
ISBN 13 : 3030169243
Total Pages : 435 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy by : Daniel M. Trifiletti

Download or read book Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy written by Daniel M. Trifiletti and published by Springer. This book was released on 2019-06-27 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive review of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT): its physics, clinical evidence, indications, and future directions. The utilization of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) is increasing internationally because of several factors. First, it offers patients a local treatment option that has demonstrated effectiveness similar to traditional surgery without the morbidity of general anesthesia and open surgical resection. Second, recent advancements in the quality of scientific evidence supporting a SRS or SBRT-containing approach in patients continues to evolve and demonstrate favorable disease-specific outcomes with little, if any, toxicity in various anatomic disease sites and for various conditions including cancer, benign tumors, and other psychiatric and neurologic conditions. Third, and most provocatively, is the notion that definitive local therapy (i.e. SRS or SBRT) in patients with cancer can boost the immune system to fight cancer in other sites throughout the body. While traditional medical knowledge would suggest that all patients with metastatic cancer are incurable, there is a mounting body of evidence that there is a subset of these patients that can be cured with definitive SRS or SBRT. This volume thus delves into each of these benefits and aspects of treatment, guiding physicians to the best treatment plan for their patients. Expert, international authors provide guidelines for SRS and SBRT use by clinicians. Chapters are divided into six main sections: Radiobiology of Radiosurgery and Stereotactic Body Radiation Therapy, Intracranial Radiosurgery Technique, Intracranial Radiosurgery by Indication, Stereotactic Body Radiation Therapy Technique, Stereotactic Body Radiation Therapy by Indication, The Future of Radiosurgery and SBRT. Overall physics are explained, as well as specific considerations for particular surgical tools (including the Leksell Gamma Knife and Accuray CyberKnife), techniques (including fractionated and charged particle radiosurgery), and anatomic sites (including brain metastases, pituitary tumors, and the prostate). Detailed images and charts enhance the chapters. This book provides physicians with a single, practical resource incorporating both of these broad categories of treatment, SRS and SBRT, and better defines the current role and the direction of radiosurgery.

Adaptive Radiation Therapy

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Publisher : CRC Press
ISBN 13 : 1439816352
Total Pages : 404 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Adaptive Radiation Therapy by : X. Allen Li

Download or read book Adaptive Radiation Therapy written by X. Allen Li and published by CRC Press. This book was released on 2011-01-27 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern medical imaging and radiation therapy technologies are so complex and computer driven that it is difficult for physicians and technologists to know exactly what is happening at the point-of-care. Medical physicists responsible for filling this gap in knowledge must stay abreast of the latest advances at the intersection of medical imaging an

Stereotactic Radiosurgery for Prostate Cancer

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Publisher :
ISBN 13 : 9783319924540
Total Pages : pages
Book Rating : 4.9/5 (245 download)

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Book Synopsis Stereotactic Radiosurgery for Prostate Cancer by :

Download or read book Stereotactic Radiosurgery for Prostate Cancer written by and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive evaluation of the use of stereotactic body radiosurgery (SBRT) for the treatment of prostate cancer. The rationale, selection criteria, and treatment planning for prostate SBRT are explained. Important imaging and anatomic considerations are discussed, and detailed consideration devoted to organ motion and tumor tracking during SBRT. Outcomes of therapy are then examined, with thorough appraisal of side effect profiles and quality of life impacts. Clear guidance is provided on how to deliver the therapy in a way that minimizes the risk of long-term urinary and rectal toxicities. Stereotactic radiosurgery for prostate cancer is an increasingly used form of treatment. Retrospective investigations have demonstrated the safe application of high-dose treatments, with 5-year results comparable to those achieved with protracted external beam radiotherapy. Prospective studies are underway comparing SBRT with more traditional forms of image-guided and intensity-modulated radiotherapy. In offering in-depth guidance on safe delivery of prostate SBRT, this book will be of value for students of radiation oncology, more experienced practitioners, and medical physicists.

Development of a Phase I/II Clinical Trial Using Sterotactic Body Radiation Therapy (SBRT) for the Treatment of Localized Prostate Carcinoma

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Publisher :
ISBN 13 :
Total Pages : 80 pages
Book Rating : 4.:/5 (227 download)

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Book Synopsis Development of a Phase I/II Clinical Trial Using Sterotactic Body Radiation Therapy (SBRT) for the Treatment of Localized Prostate Carcinoma by :

Download or read book Development of a Phase I/II Clinical Trial Using Sterotactic Body Radiation Therapy (SBRT) for the Treatment of Localized Prostate Carcinoma written by and published by . This book was released on 2006 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic body radiation therapy (SBRT) is a new therapeutic paradigm for treating localized tumors outside of the central nervous system and involves delivering very high doses of focused radiation using unique beam arrangements and special immobilization equipment. It has also been shown recently that many prostate cancers may be better controlled using large dose per fraction treatments such as might be delivered by SBRT. While large dose per fraction treatments are facilitated by new generation radiation delivery equipment, technology cannot independently overcome normal tissue consequences to tubular organs adjacent or within targets (e.g., the urethra and rectum for prostate cancer). As such, careful prospective clinical trials must be designed that appropriate bridge the information learned from laboratory testing, historical clinical experience, and the clinical experience with SBRT from other sites in order to test this new therapy for prostate cancer. Our goal is ultimately to carry out a prospective phase I/II trial of SBRT for treatment of localized prostate cancer such that its true efficacy and toxicity might be characterized. The objective of this application is to establish the collaborations necessary for formulating these protocols, write the protocols, assemble the clinical research infrastructure necessary for submitting the protocols, set up mechanisms for multi-center participation with our center acting as the coordinating center, recruiting, enrolling, treating and following patients, and to support the research infrastructure and clinical researchers performing these tasks.

Hypofractionated and Stereotactic Radiation Therapy

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Author :
Publisher : Springer Nature
ISBN 13 : 3031477014
Total Pages : 560 pages
Book Rating : 4.0/5 (314 download)

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Book Synopsis Hypofractionated and Stereotactic Radiation Therapy by : Orit Kaidar-Person

Download or read book Hypofractionated and Stereotactic Radiation Therapy written by Orit Kaidar-Person and published by Springer Nature. This book was released on with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Insights for Image-Guided Radiotherapy

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Publisher : CRC Press
ISBN 13 : 1040043747
Total Pages : 165 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Clinical Insights for Image-Guided Radiotherapy by : Mike Kirby

Download or read book Clinical Insights for Image-Guided Radiotherapy written by Mike Kirby and published by CRC Press. This book was released on 2024-07-10 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a clinical insight into image-guided radiation therapy (IGRT) for prostate cancer. It starts by setting the clinical scene, discussing immobilisation and standard IGRT practice and then considering important developments like IGRT with non-ionising radiation, adaptive radiotherapy, particle therapy, margins, hypofractionation, clinical outcomes, AI and training. Good IGRT requires both technical and clinical focus. So, in complement to our first study guide on IGRT, this book now brings together key, clinical insights into IGRT for Prostate Cancer patients, with a view to helping the professional learn more about ‘how-to’ undertake IGRT for these patients more accurately, effectively and safely, throughout the whole course of a patient’s treatment with radiation. This clinical insight guide will be of interest to newly qualified radiation therapists, therapeutic radiographers, medical dosimetrists, medical physicists, radiotherapy physicists and clinical oncologists. It will also be of use for trainees and can be used alongside continuing competency and clinical training within real clinical departments and radiation therapy centres worldwide. This is the first in a forthcoming series of clinical insights, each tackling a different treatment area. Further areas in the series will be: Head and Neck; Thorax; Breast; Pelvis; and the Brain. Key Features: • Internationally applicable, clinically focused, up-to-date and evidence based. · Accompanied by suitable electronic multimedia resources. · Authored by experts with decades of experience of pioneering electronic portal imaging and IGRT in clinical practice, pedagogic research and substantial experience of teaching/supervising students, trainees and qualified therapists/medical physicists at bachelors, postgraduate and doctoral levels. Mike Kirby and Kerrie-Anne Calder are well-respected authors and radiotherapy professionals, who have worked in radiotherapy physics/radiotherapy clinical and academic practice for nearly 35 years and 25 years respectively. Mike Kirby is a Senior Lecturer in Radiotherapy Physics at the University of Liverpool, UK, and an Honorary Lecturer at the University of Manchester, UK. He holds graduate and postgraduate qualifications in medical physics and has in total over 200 books, papers, oral and poster presentations to his name in the field of radiotherapy. Dr. Kirby holds professional membership of the Institute of Physics and Engineering in Medicine, the American Association of Physicists in Medicine, the American Society for Radiation Oncology, the European Society for Radiotherapy and Oncology and the British Institute of Radiology, is a Fellow of the Higher Education Academy and the British Institute of Radiology in the UK. Kerrie-Anne Calder is a Lecturer at the University of Liverpool, UK, where she educates undergraduate and post graduate students in many aspects of radiotherapy with a special interest and role in imaging training. Kerrie-Anne has graduate and postgraduate qualifications in radiotherapy, education and academic practice, is a member of the Society and College of Radiographers, and is a Fellow of the Higher Education Academy in the UK. She was a clinical and professional lead in IGRT (on-treatment verification imaging) within the NHS in the UK for over ten years.

Technical Basis of Radiation Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642115713
Total Pages : 1145 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Technical Basis of Radiation Therapy by : Seymour H. Levitt

Download or read book Technical Basis of Radiation Therapy written by Seymour H. Levitt and published by Springer Science & Business Media. This book was released on 2012-01-25 with total page 1145 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a detailed examination of the technological basis of radiation therapy. It is jointly written by North American and European authors, which broadens the contents and increases the book’s applicability in daily practice throughout the world.