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Choline And Acetylcholine Handbook Of Chemical Assay Methods
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Book Synopsis Handbook of Neurochemistry by : Abel Lajtha
Download or read book Handbook of Neurochemistry written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is concerned with the enzymes of the nervous system. Cerebral enzymes form the basis of the functional brain. They are needed for the control of the energetics of the nervous system, whether it be their release or their direction; for the elaboration of transmitters and for their destruction; for the synthesis, transport, and breakdown of all metabolites of the nervous system. They are indispensable for the control of the multitude of factors that govern our thinking and our behavior. They make it possible for us to comprehend what is taking place around us and perhaps to understand what may be in store for us. Enzymes are the stuff of life, and no living cell can be without them. They are the results of many millions of years of evolution, from the time when biological membranes first came into being and were folded to produce the first cells within which the earliest enzymes were wrought. Countless changes have taken place within them, so that, now, only those enzymes exist that play specific roles in the functions of the living cells of today. Those in the nervous system possess a mUltiple role: in the creation, maintenance, and ultimate breakdown of the component cells and in enabling consciousness, perception, memory, and thought to become possible. But though life may go on forever, the enzymes that make life possible will undergo the many changes involved in the evolutionary process.
Book Synopsis Brain Acetylcholine and Neuropsychiatric Disease by : Kenneth L. Davis
Download or read book Brain Acetylcholine and Neuropsychiatric Disease written by Kenneth L. Davis and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have witnessed a resurgence of interest in the possible role of brain acetylcholine in neuropsychiatric disease. Research in this area has involved the renewed investigation of the cholinomimetics physostigmine and arecoline, and has been facilitated by the development of new potential cholinomimetics such as dimethylaminoethanol (Deanol) and choline chloride. Current investigators also have taken advantage of new approaches to neurochemical studies. Increasingly sensitive assay techniques such as gas chromatography/mass spectrometry have allowed investigators to measure low concentra tions of choline and acetylcholine in brain tissues. Improved neuroanatomical procedures such as immunohistochemical staining and the use of microelectrodes and micropipets have enabled skilled investigators to begin to map central acetylcholine pathways and to dissect the component parts of the complex interactions between brain acetylcholine and other neurotransmitters. The convergence of data from both clinical and basic studies now suggest that brain acetylcholine may be involved in affective illness, several movement disorders, and some cognitive disturbances. The purpose of this book is to summarize recent clinical and pre-clinical investigations on the possible role of brain acetylcholine in several neurological and psychiatric disorders. The volume is divided into six major sections: (1) Brain Acetylcholine and Psychiatric Disorders; (2) Brain Acetylcholine and Movement Disorders; (3) Brain Acetylcholine and Cognitive Function; (4) The Electrophysiology of Cholinergic Agents; (5) Interactions of Brain Acetylcholine and Other Neurotransmitters; (6) Biochemical and Pharmacological Aspects of CholinergiC Treatment Strategies.
Book Synopsis Neurochemical Techniques in Insect Research by : H. Breer
Download or read book Neurochemical Techniques in Insect Research written by H. Breer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurochemical Techniques in Insect Research properly emphasizes the insect. It only scratches the surface of the exploding repertoire of general neuro chemical techniques that can be applied to insect research in 1985. But it al so presents the advantages of using insects for studying certain biological questions that are approachable by neurochemical techniques. Even more so, it summarizes the long list of unique problems encountered in attempting to study insects by neurochemical techniques. As in other volumes of this series, the contributors to this volume are the authorities in the field. They themselves have developed much of the material presented. Thus the sum effort provides a true description of the state of the art; and, pleasantly, it does so in a very complete and clear manner. Readers of this series will not need to be reminded that, despite the fact that vertebrates make up only about 3% of all animal species, research in in vertebrates such as insects has lagged behind that on vertebrates, at least in the neurochemistry area; the relative simplicity and large cell size of the in sect nervous system has always provided incentive for work in neurophysiol ogy and neuroanatomy. Toxicology interests will always stimulate a certain amount of work on insect neuropharmacology, and insects are extremely suitable for several areas of toxin research. Last but not least, the insects are beautiful organisms for which the applications of genetics can be made to the study of nervous system function.
Book Synopsis Cholinergic Mechanisms and Psychopharmacology by : D. Jenden
Download or read book Cholinergic Mechanisms and Psychopharmacology written by D. Jenden and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 867 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents a collection of papers which were contributed by participants at a Symposium for Cholinergic Mechanisms and Psycho pharmacology, held in La Jolla, California on March 28-30, 1977. The were chosen to emphasize areas in which there has been substantial topics progress in the past 2-3 years and fall into seven major groups dealingwith: cholinergiC receptors; chemistry, histochemistry and enzymology; cyclic nucleotides and cholinergiC mechanisms; storage, compartmentation and release of acetylcholine; regulatory mechanisms in acetylcholine metab olism; modulation of acetylcholine metabolism; and behavioral and clin ical manifestations of cholinergiC function and dysfunction. Each group contains one or more reviews and a number of shorter contributions de scribing current work. This symposium was the third in a series of which the first two were held in Skokloster, Sweden in 1970 and Boldern, Switzerland in 1974. The Proceedings of the meetings indicate a rapid development of knowledge of cholinergiC mechanisms which for many years lagged behind that of other neurotransmitters and neuroregulators. The inclusion of a large section in the present volume dealing with clinical manifestations of cholinergiC dysfunction reflects one of the most important trends in current research on cholinergiC mechanisms, namely the close inter-relationship and mutual support of basic science and clinical investigation. I hope that this volume will be of value to all those whose work relates to cholinergiC function, at both basic and clinicalleve18, and will continue to stimulate the vigorous exchange of ideas which was such a prominent feature of the Symposium.
Book Synopsis Journal of Pharmacological Methods by :
Download or read book Journal of Pharmacological Methods written by and published by . This book was released on 1980 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Choline and Acetylcholine: Handbook of Chemical Assay Methods by : Israel Hanin
Download or read book Choline and Acetylcholine: Handbook of Chemical Assay Methods written by Israel Hanin and published by . This book was released on 1974 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Cholinergic Synapse by : Victor P. Whittaker
Download or read book The Cholinergic Synapse written by Victor P. Whittaker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most impressive works of scholarship in the field of experimental pharmacology has been the Heffter-Heubner Handbuch der experimentellen Pharmakologie, internationalized some years ago under the title Handbook 0/ Experimental Pharmacology and kept up to date by a series of numbered Ergiin zungswerke or supplementary volumes which have now replaced in importance the original Handbuch. These volumes constitute a valuable and continuously up dated multi author review series of topics important in modern pharmacology and allied sciences. The Editorial Board of the Handbook invited me 2 years ago to undertake, as subeditor, the preparation of a new volume entitled The Cholinergic Synapse. A previous volume in this series, vol. 15, Cholinesterases and Anticholinesterase Agents, edited by GEORGE KOELLE, was published in 1963 and was far wider in scope than its title suggested: it was, in fact an authoritative summing up of the whole subject of cholinergic function and still has some value today as an account of the state of the art as it was at that time. Since then another excellent review, of a specific cholinergic synapse, has appeared in this series: this was vol. 42, Neuromuscular Junction, edited by ELEANOR ZAIMIS and published in 1976. A third volume, vol. 53, Pharmacology o/Ganglionic Transmission, which appeared in 1980 and was edited by D. A. KHARKEVICH, includes important aspects of autonomic cholinergic function.
Book Synopsis Central Neurotransmitter Turnover by : C. J. Pycock
Download or read book Central Neurotransmitter Turnover written by C. J. Pycock and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of chemical transmission in the central nervous system has taken some time to be generally accepted, but an increasing number of compounds are now being recognized as hav ing a transmitter role in the brain. The acetylcholine system was the first to be discovered in the periphery and its charac teristic features of storage of transmitter in vesicles in the nerve terminal, its electrically-evoked release and rapid extra neuronal breakdown were considered to be necessary criteria for any neurotransmitter candidate. The subsequent elucidation of the noradrenergic system made it apparent that rapid enzymatic breakdown was not essential for a released transmitter, and the possibility of high-affinity re-uptake processes became establ ished as an alternative means of terminating the synaptic actions of a transmitter. With the eventual acceptance of the amino acids as excitat ory or inhibitory transmitters, the requirement for a transmit ter to be present in a low concentration overall (although locally concentrated in specific terminals) also had to be discarded. This necessitated the additional concept of specif ic metabolic pools with different functions being located in different cells or within different regions of the same cell. Some localization of glutamate and aspartate remote from excit able membranes is clearly essential since their overall brain concentrations would be sufficient to maximally depolarize the majority of neurones in the brain. The concept of separate metabolic pools has been supported by stUdies on turnover rate (see Chapter 5).
Book Synopsis Cholinergic Mechanisms by : Peter Gaudenz Waser
Download or read book Cholinergic Mechanisms written by Peter Gaudenz Waser and published by . This book was released on 1975 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1974 with total page 1242 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Book Synopsis Neuroethology and Behavioral Physiology by : F. Huber
Download or read book Neuroethology and Behavioral Physiology written by F. Huber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: The investigation of the relationships between a behavior pattern and its underlying sensory and neurophysiological mechanisms in both man and animals dates back well into the last century. However, the concepts and findings of ethology and experimental psychology, together with an improved understanding of how the nervous system is organized and how neurons interact with each other, have only in the last 30 years laid the groundwork for an in-depth analysis. The many technological advances achieved in neurophysiology and neuroanatomy have also played an important role in this. The study of the neuronal bases of behavior - for which the term "neuroethology" has been coined - has thus become one of the central themes of neuroscience. Kenneth David Roeder, who died in 1979, was one of the pioneers of this field of research. It is to him that the contributions in this book are dedicated. K.D. Roeder was among the first to attempt to define the correlation between the natural behavior of an experimental animal and the activity of single sensory and nerve cells. The ques tions he asked, his experimental approach, and his fundamental discoveries are pre sented in an introductory chapter.
Book Synopsis Laboratory Tests for the Assessment of Nutritional Status by : Howerde E. Sauberlich
Download or read book Laboratory Tests for the Assessment of Nutritional Status written by Howerde E. Sauberlich and published by Routledge. This book was released on 2018-12-19 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proper nutrition is the single most important component of preventative health care. Heart disease, diabetes, and other ailments are all linked to dietary habits. Accurate nutritional assessment can be a matter of life or death. Laboratory Tests for the Assessment of Nutritional Status explores the expanded number of nutrients that can now be evaluated. The author makes a compelling case for the practice and advancement of this critical health care tool. Nutritional assessment identifies undernutrition, overnutrition, specific nutrition deficiencies, and imbalances. Diligent assessment determines the appropriate nutrition intervention and monitors its effects. This book is a total revision of the 1974 version of the same title co -authored by Sauberlich. Since then, remarkable progress has been made on the methodologies applicable to nutrition status assessment and to the expanded number of nutrients that can be evaluated, especially trace elements. The introduction of high-performance liquid chromatography, amperometric detectors, and other technologies has advanced nutritional assessment by leaps and bounds. Today, nutritionists can gauge the value of microminerals, trace elements, and ultratrace elements. Sauberlich's revision updates the reader to the latest and most important trends in nutrition. These laboratory methods for the assessment of nutritional status are vital for identifying individuals as well as populations with nutritional risks.
Book Synopsis Neuromuscular Junction by : R.E.M. Bowden
Download or read book Neuromuscular Junction written by R.E.M. Bowden and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Has the neuromuscular junction been over-exposed or is it perhaps already a closed book? I asked myself this at a recent International Congress when an American colleague complained that the Journal of Physiology had articles on nothing but the neuromuscular junction, while another colleague asked why I was editing a volume on a subject about which everything was already known. It is worrying to think that these views may be shared by other people. I hope that this volume will convince my two colleagues and other readers that the neuromuscular junction is very much alive and continues to attract the interest of many workers from a variety of fields; strange as it may seem, the synapse between a motor nerve ending and muscle fibre, with its relatively simple architecture, is one of the most inter esting sites in the body-I do hope we have done it justice. The various chapters of this volume present a cross section of knowledge as viewed by a group of 13 individuals, actively engaged in research. Multi-author volumes such as this are frequently criticised on the grounds that chapters or sec tions overlap. I believe that such criticium is only valid where the overlap is repetitious. Where it results in the reader having available discussions of material from differing stand-points, overlap becomes a valuable feature of this type of publication.
Book Synopsis Commentaries in Plant Science by : Harry Smith
Download or read book Commentaries in Plant Science written by Harry Smith and published by Elsevier. This book was released on 2016-07-29 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Commentaries in Plant Science is a compilation of reviews of recent developments in pure and applied plant science. It covers a wide range of topics such as carboxylation, photorespiration, carbon assimilation, mating reaction, protein evolution, recombination, and photoperiodic induction. The book is comprised of 21 commentaries and begins with some of the physiological processes in C4 plants. The succeeding chapters deal with stomatal control of entry of air pollutants, mating reactions in yeasts, uptake and expression of DNA by plants, mechanics and metabolisms of guard cells, breeding for modified fatty acid composition, gravity sensing mechanism and response mechanism of root caps. It also outlines the functions of lectins, plant virus inhibitors, and cytokinins. Research workers, teachers and students who wish to broaden their knowledge about plant science will find this book very useful.
Book Synopsis Handbook of Vitamins by : Lawrence J. Machlin
Download or read book Handbook of Vitamins written by Lawrence J. Machlin and published by Marcel Dekker. This book was released on 1991 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Completely updated and expanded to reflect the latest literature on vitamins in a reference tool fashion, the book presents reviews of vitamins, their chemistry and metabolism along with some 230 diagrams and tables and 3,200 citations. Vitamins covered are vitamins A, D, E, K, C, B6, B12, thiamin, riboflavin, nicotinic acid, biotin, pantothenic acid, folic acid, choline, carnitine, and substances without vitamin status.
Book Synopsis Dynamics of Cholinergic Function by : Israel Hanin
Download or read book Dynamics of Cholinergic Function written by Israel Hanin and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 1242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book incorporates the proceedings of the Fifth International Cholinergic Conference, which took place in Oglebay Park, West Vir ginia, USA, on October 30th to November 4th, 1983. A scenic forty five minute ride from the City of Pittsburgh, surrounded by champion ship golf courses, luxurious woods and a picturesque lake, Oglebay provided relaxed and beautiful surroundings, conducive to contem plation, stimulating discussions and, thought-provoking scientific sessions. Over 160 individuals from allover the world participated in the sessions. The meeting was sub-divided into oral presentations, round table discussions and poster sessions, and centered upon ten key topics of cholinergic relevance (see Table of Contents). Following in the tradition of the four International Conferences which had preceded this one, the Conference featured the most up to-date developments in the area of cholinergic mechanisms, and provided for ample and productive discussion of new fields and di rections in this area. Moreover, both senior investigators in the field as well as recent newcomers to this sphere of investigation participated in the proceedings. This book, touches on a wide array of mechanisms and applications - from the preclinical to the clinical level. It should thus be useful as a comprehensive resource, with the cholinergic system as a focal hub. The Conference could not have been as successful as it turned out to be, without the support of a number of important contributors.
Book Synopsis Scientific Directory and Annual Bibliography by : National Institutes of Health (U.S.)
Download or read book Scientific Directory and Annual Bibliography written by National Institutes of Health (U.S.) and published by . This book was released on 1974 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each issue lists papers published during the preceding year.
