Cholecystokinin And Its Antagonists In Pain Management

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Cholecystokinin and Its Antagonists in Pain Management

Author : Gary McCleane
Publisher : CRC Press
ISBN 13 : 9780789028938
Total Pages : 162 pages
Book Rating : 4.0/5 (289 download)

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Book Synopsis Cholecystokinin and Its Antagonists in Pain Management by : Gary McCleane

Download or read book Cholecystokinin and Its Antagonists in Pain Management written by Gary McCleane and published by CRC Press. This book was released on 2006-06-22 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examine the strong evidence of this unrealized pain management tool Cholecystokinin (CCK), the regulatory peptide hormone found primarily in the gastrointestinal tract that works as a neurotransmitter throughout the nervous system, has been researched for years. CCK antagonists in conjunction with opioids are beginning to be seen as having possible major therapeutic benefits in pain management. Cholecystokinin and Its Antagonists in Pain Management is an extensive examination that gathers the mounting compelling evidence into one comprehensive source. Here researchers, neuroscientists, physicians, and pharmacy professionals are given the research and findings they need to explore the possible applications of CCK antagonists for a variety of illnesses. Cholecystokinin and Its Antagonists in Pain Management extensively describes opioids in pain management, CCK and the body’s uses for the chemical, CCK receptor antagonists, and the evidence that points to its being a possible breakthrough application in pain management. Various animal studies are offered that present a convincing view of what may be the future of chronic pain management, with less side effects and a reduction in analgesic tolerance than when opioids are used alone. Potential uses of CCK antagonists are clearly discussed. The book is comprehensively referenced and provides several tables and graphs to fully illustrate the research findings. Topics in Cholecystokinin and Its Antagonists in Pain Management include: in vivo localization of CCK CCK as a gut and nervous system peptide factors that increase CCK anti-opioid effects CCK receptor antagonists pro-analgesic effect of CCK antagonists CCK antagonists reducing analgesic tolerance to opioids safety of combining opioids and CCK antagonists human clinical application of CCK antagonists Cholecystokinin and Its Antagonists in Pain Management is a crucial source of the latest information and research results on CCK that is certain to be important for neuroscientists, clinicians, and pharmaceutical industry professionals.

Cholecystokinin Antagonists in Gastroenterology

Author : Guido Adler
Publisher : Springer Science & Business Media
ISBN 13 : 3642763626
Total Pages : 345 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Cholecystokinin Antagonists in Gastroenterology by : Guido Adler

Download or read book Cholecystokinin Antagonists in Gastroenterology written by Guido Adler and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new presentation of physiological regulatory mechanisms and therapeutic applications is given in this book. It represents a collection of the most up-to-date information in cholecystokinin (CCK) research, especially focusing on the development and characterization of CCK antagonists. The book contains chapters on the synthesis, biochemical and pharmacological characterization of potent and selective CCK antagonists as well as physiological applications of these compounds. The last section of the book is devoted to the involvement of CCK in pathological states and potential clinical applications of CCK antagonists.

Cholecystokinin Antagonists in Gastroenterology

Author : Guido Adler
Publisher : Springer
ISBN 13 : 9783540535829
Total Pages : 233 pages
Book Rating : 4.5/5 (358 download)

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Book Synopsis Cholecystokinin Antagonists in Gastroenterology by : Guido Adler

Download or read book Cholecystokinin Antagonists in Gastroenterology written by Guido Adler and published by Springer. This book was released on 1991-09-27 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new presentation of physiological regulatory mechanisms and therapeutic applications is given in this book. It represents a collection of the most up-to-date information in cholecystokinin (CCK) research, especially focusing on the development and characterization of CCK antagonists. The book contains chapters on the synthesis, biochemical and pharmacological characterization of potent and selective CCK antagonists as well as physiological applications of these compounds. The last section of the book is devoted to the involvement of CCK in pathological states and potential clinical applications of CCK antagonists.

Acute Pain Management

Author : Raymond S. Sinatra
Publisher : Cambridge University Press
ISBN 13 : 0521874912
Total Pages : 729 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Acute Pain Management by : Raymond S. Sinatra

Download or read book Acute Pain Management written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2009-04-27 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.

The Essence of Analgesia and Analgesics

Author : Raymond S. Sinatra
Publisher : Cambridge University Press
ISBN 13 : 1139491989
Total Pages : 551 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis The Essence of Analgesia and Analgesics by : Raymond S. Sinatra

Download or read book The Essence of Analgesia and Analgesics written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2010-10-14 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Essence of Analgesia and Analgesics is an invaluable practical resource for clinicians giving pain relief in any clinical setting, describing the pharmacologic principles and clinical use of all available pain medications. As well as detailed overviews of pain processing and analgesic theory, sections are dedicated to oral and panteral opioid analgesics, neuraxial opioids, NSAIDs, local anesthetics, anticonvulsant type analgesics, NMDA antagonists, alpha adrenergic analgesics, antidepressant analgesics, muscle relaxants, adjuvant medications, and new and emerging analgesics. The concise format of the chapters allows for quick and easy reading and assimilation of information. Enhanced by summary tables and figures, each chapter provides an overview of a particular drug, covering chemical structure, mode of activity, indications, contraindications, common doses and uses, advantages and disadvantages, and drug related adverse events. Key references are also provided. Edited by leading experts in pain management, this is essential reading for any clinician involved in pain management.

Regional Anaesthesia Analgesia and Pain Management

Author : M. Tiengo
Publisher : Springer Science & Business Media
ISBN 13 : 8847022401
Total Pages : 332 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Regional Anaesthesia Analgesia and Pain Management by : M. Tiengo

Download or read book Regional Anaesthesia Analgesia and Pain Management written by M. Tiengo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Local-regional anesthesia and pain therapy represent two areas of common interest for all physicians. A thorough preparation in functional anatomy and general pharmacology, including familiarity with local anesthetics and analgesics, is considered fundamental background for further study or clinical application of such techniques. Knowledge of the mechanisms of action, efficacies and side effects of the relevant drugs is essential, as is appreciation of possible drug interactions to evaluate eventual toxic effects. Local-regional anesthesia and pain management are being increasing used in diverse medical specialties, including those requiring manual dexterity. In contemporary medicine correct evaluation of the medical outcome becomes essential, especially in relation to the cost-benefit balance, not only in terms of the resources consumed, also and more importantly for the quality of life of the patient.

Nuclear Hepatology

Author : Gerbail T. Krishnamurthy
Publisher : Springer Science & Business Media
ISBN 13 : 3642006485
Total Pages : 365 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Nuclear Hepatology by : Gerbail T. Krishnamurthy

Download or read book Nuclear Hepatology written by Gerbail T. Krishnamurthy and published by Springer Science & Business Media. This book was released on 2009-06-23 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of Nuclear Hepatology almost 10 years ago, new advances have taken place, both in our understanding of liver pathophysiology and various imaging modalities. A unique feature of imaging of physiology is that it enables quanti- cation. Since liver physiology is complex, quantification has been a challenge. Many p- lications in the past have often included quantification based on home-made software not available for others. Thus, the comparison of results from one center to another becomes difficult, if not impossible. The second edition of Nuclear Hepatology addresses these issues. Sophisticated software for liver and gallbladder function has been tested and va- dated through many of our previous publications. Now that software is FDA approved and available for others through a commercial company, it is hoped that future publications of imaging of liver and gallbladder physiology would routinely include quantification. Although the function of the hepatocyte is complex, it can be broadly divided into two main categories, substrate uptake at the basolateral border and intracellular transit prior to excretion into the canaliculi. The earliest manifestation of hepatocellular injury occurs in the form of prolongation of the intracellular transit time, which occurs long before the disruption of the basolateral border with subsequent rupture and death. The liver enzymes are released into circulation after the death of the hepatocyte.

Fundamentals of Anaesthesia

Author : Colin Pinnock
Publisher : Cambridge University Press
ISBN 13 : 9780521690799
Total Pages : 990 pages
Book Rating : 4.6/5 (97 download)

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Book Synopsis Fundamentals of Anaesthesia by : Colin Pinnock

Download or read book Fundamentals of Anaesthesia written by Colin Pinnock and published by Cambridge University Press. This book was released on 2002-12 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.

Pain Management

Author : Gary J. McCleane
Publisher : John Wiley & Sons
ISBN 13 : 1444300806
Total Pages : 200 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Pain Management by : Gary J. McCleane

Download or read book Pain Management written by Gary J. McCleane and published by John Wiley & Sons. This book was released on 2009-01-26 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conventional pharmaceutical approaches to pain management are notalways successful. Using only those medications that have anofficial indication for a certain condition reducessubstantially the chance of the patient gaining pain relief and mayexpose them to intolerable side effects. However evidence nowexists on the use of other drugs, produced for non-pain conditions,and how they can substantially increase the chances of pain relief. Covering the most recent developments in this field, McCleaneoffers an alternative solution to pain treatment when conventionaltreatments fail. This pioneering book proposes evidence-basedalternatives to current options in pain management, usingwell-grounded rationales for each given treatment. This book is an ideal reference for the specialist andnon-specialist prescriber alike and for practitioners from a widevariety of disciplines. It provides the evidence required andtreatment algorithms for readers to use the drugs appropriately andto explore the field if they wish.

Mechanisms of Vascular Disease

Author : Robert Fitridge
Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Opioids in Non-Cancer Pain

Author : Catherine F. Stannard
Publisher : Oxford University Press
ISBN 13 : 0199678073
Total Pages : 121 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Opioids in Non-Cancer Pain by : Catherine F. Stannard

Download or read book Opioids in Non-Cancer Pain written by Catherine F. Stannard and published by Oxford University Press. This book was released on 2013-03-21 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: This pocketbook summarizes the recent developments in this important and controversial aspect of pain management, looking at the benefits and adverse effects of opioids in non-cancer pain.

The Effects of Drug Abuse on the Human Nervous System

Author : Bertha Madras
Publisher : Elsevier
ISBN 13 : 0124186858
Total Pages : 625 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis The Effects of Drug Abuse on the Human Nervous System by : Bertha Madras

Download or read book The Effects of Drug Abuse on the Human Nervous System written by Bertha Madras and published by Elsevier. This book was released on 2013-11-15 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers. A comprehensive reference on the effects of drug addiction on the human nervous system Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs Includes foundational science chapters on the biology of addiction Details challenges in diagnosis and treatment options

Acute Pain Management

Author : Pamela E. Macintyre
Publisher :
ISBN 13 : 9780977517442
Total Pages : 491 pages
Book Rating : 4.5/5 (174 download)

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Book Synopsis Acute Pain Management by : Pamela E. Macintyre

Download or read book Acute Pain Management written by Pamela E. Macintyre and published by . This book was released on 2010-01-01 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essential Clinical Anesthesia Review

Author : Linda S. Aglio
Publisher : Cambridge University Press
ISBN 13 : 1316062287
Total Pages : 577 pages
Book Rating : 4.3/5 (16 download)

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Book Synopsis Essential Clinical Anesthesia Review by : Linda S. Aglio

Download or read book Essential Clinical Anesthesia Review written by Linda S. Aglio and published by Cambridge University Press. This book was released on 2015-01-08 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise, evidence-based board review book, organized according to the ABA keyword list, covers all the fundamental concepts needed to pass written and re-certification board examinations. Each chapter begins with a case scenario or clinical problem from everyday practice, followed by concise discussion and clinical review questions and answers. Discussion progresses logically from preoperative assessment and intraoperative management to postoperative pain management, enhancing the reader's knowledge and honing diagnostic and clinical management skills. New guidelines and recently developed standards of care are also covered. Serving as a companion to the popular textbook Essential Clinical Anesthesia, this resourceful work reflects the clinical experiences of anesthesia experts at Harvard Medical School as well as individually known national experts in the field of anesthesiology. This practical review is an invaluable resource for anesthesiologists in training and practice, whether studying for board exams or as part of continuing education and ABA recertification.

Handbook of Biologically Active Peptides

Author : Abba Kastin
Publisher : Academic Press
ISBN 13 : 0123850967
Total Pages : 2033 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Handbook of Biologically Active Peptides by : Abba Kastin

Download or read book Handbook of Biologically Active Peptides written by Abba Kastin and published by Academic Press. This book was released on 2013-01-26 with total page 2033 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Biologically Active Peptides, Second Edition, is the definitive, indispensable reference for peptide researchers, biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and endocrinologists. Its chapters are designed to be a source for workers in the field and enable researchers working in a specific area to examine related areas outside their expertise. Peptides play a crucial role in many physiological processes, including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The second edition of Handbook of Biologically Active Peptides presents this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. Presents all aspects of biologically active peptides in one resource Features more than 20 sections spanning plant, bacterial, fungal, venom, and invertebrate peptides to general peptides Includes immunological, inflammatory, cancer, vaccine, and neurotrophic peptides Discusses peptide precursors, mRNA distribution, processing, and receptors, not just pathophysiological implications

The Pain Management Handbook

Author : M. Eric Gershwin
Publisher : Springer Science & Business Media
ISBN 13 : 1461217962
Total Pages : 400 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis The Pain Management Handbook by : M. Eric Gershwin

Download or read book The Pain Management Handbook written by M. Eric Gershwin and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Those who do not feel pain seldom think that it is felt. SAMUEL JoHNSON, The Rambler, no. 48 (September 1, 1750) Who among us has not experienced the suffering of a patient with chronic disease, who in addition to the vicissitudes of fatigue, anxiety, and frustration, must also deal with the suffering of pain? Who among us has not considered, and then reconsidered, whether a patient's complaints are worthy of a narcotic and thence worried about the social and legal implications of chronic use? Who among us has not refused pain medications to our patients for fear that use was turning into abuse? Finally, who among us would not have liked a clinical guide to a myriad of syndromes, all of which have pain as their common denominator, in the hopes of developing some strategy to prioritize treatment. Our purpose in preparing The Pain Management Handbook is to provide the informa tion needed by clinicians to develop strategies that optimize pain management. It is the goal of the editors and authors that the present handbook, above all else, will be clinically useful. Its aim is to provide practical information regarding the diagnosis and treatment of disorders causing pain, along with tables and graphics to provide the busy practitioner with rapid access to relevant data.

Cousins and Bridenbaugh's Neural Blockade in Clinical Anesthesia and Pain Medicine

Author : Michael J. Cousins
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451178654
Total Pages : 1360 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Cousins and Bridenbaugh's Neural Blockade in Clinical Anesthesia and Pain Medicine by : Michael J. Cousins

Download or read book Cousins and Bridenbaugh's Neural Blockade in Clinical Anesthesia and Pain Medicine written by Michael J. Cousins and published by Lippincott Williams & Wilkins. This book was released on 2012-03-29 with total page 1360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, authoritative text presents the scientific foundations and clinical practice of neural blockade in both regional anesthesia and the management of pain. The descriptions and illustrations of pain mechanisms are considered classic examples. The Fourth Edition has been refined for clarity and flows logically from principles and pharmacology, to techniques for each anatomic region, to applications. This edition has two new co-editors and several new chapters on topics including neurologic complications, neural blockade for surgery, treatment of pain in older people, and complications in pain medicine. A companion Website will offer the fully searchable text and an image bank.