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Author : Jianwen Fang
Publisher :
ISBN 13 :
Total Pages : 338 pages
Book Rating : 4.:/5 (467 download)
Download or read book Chemo-enzymatic Synthesis of [alpha]-Gal Oligosaccharides written by Jianwen Fang and published by . This book was released on 2000 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Hongmei Huang
Publisher :
ISBN 13 :
Total Pages : 610 pages
Book Rating : 4.:/5 (763 download)
Download or read book Chemo-enzymatic Synthesis of Oligosaccharides and Carbohydrate Mimetics written by Hongmei Huang and published by . This book was released on 1995 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapter I: Design and synthesis of SLe sp{\rm x} Mimetics. The design and synthesis of several SLe sp{\rm x} mimetics are described. In mimetic A, an ethylene glycol linkage bridges the fucose and galactose moieties, and a carboxymethyl group replaces the sialic acid. In mimetic B, a scD-tartaric acid derivative replaces the trans-3,4-dihydroxyl groups of the glucosamine, and links the fucose and carboxypentyl groups. These compounds were tested as inhibitors of the binding of SLe sp{\rm x} to E-selectin. Mimetic C contains a macrocyclic structure which restricts the conformation by linking the fucose and galactose moieties. Mimetic D is a glycopeptide derived from the structure of B. Mimetics C and D are expected to show better binding activities than compound A and B, respectively. Chapter II: Enzymes in organic chemistry. (1) A strategy was developed for the enzymatic solid-phase synthesis of tetrasaccharide rm NeuAc\alpha2 \to 3Gal\beta1 \to 4GlcNAc\beta1 \to 3Gal, an inhibitor of the attachment of H. pylori to mucous cells. The conversion for each step was found to be > 98%. (2) Several oligosaccharides containing negatively charged groups, sulfates or carboxylates, were synthesized for the substrate specificity study of glycosyltransferases potentially responsible for the biosynthesis of the natural ligand(s) for L-selectin. (3) Preliminary research is reported on the application of galactose oxidase for the synthesis of a potential substrate for alpha -2,3-fucosyltransferase VII, as well as other oligosaccharides. An improved procedure was developed for the GOase catalyzed oxidation of weak substrates to nearly completion. (4) A kinetics study of the lipase resolution of alcohol 82, and other nucleophiles, was performed for comparison to the antibody 21H3 catalyzed transesterification. The product inhibition and solvent effects were also discussed. (5) The regioselectivity of the transesterification of disaccharides catalyzed by enzymes such as subtilisin was investigated. Conditions were optimized to obtain either a 6 sp\prime -monoacetylated compound or a 6,6 sp\prime -diacetylated compound as the major product.
Author : Arne Homann
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (56 download)
Download or read book En Route to Tailor-made Oligosaccharides written by Arne Homann and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert John Kerns
Publisher :
ISBN 13 :
Total Pages : 464 pages
Book Rating : 4.:/5 (814 download)
Download or read book Studies on the Chemo-enzymatic Synthesis of Glycosaminoglycan Oligosaccharides written by Robert John Kerns and published by . This book was released on 1996 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Andrea Marchesi
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (129 download)
Download or read book Chemo-enzymatic Strategies for the Synthesis of Oligosaccharides written by Andrea Marchesi and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Masatake Ōnishi
Publisher :
ISBN 13 :
Total Pages : 282 pages
Book Rating : 4.F/5 ( download)
Download or read book Glycoenzyme written by Masatake Ōnishi and published by . This book was released on 2000-02 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ajit Varki
Publisher : CSHL Press
ISBN 13 : 9780879696818
Total Pages : 694 pages
Book Rating : 4.6/5 (968 download)
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author : Chi-Huey Wong
Publisher : Elsevier
ISBN 13 : 9780080359410
Total Pages : 392 pages
Book Rating : 4.3/5 (594 download)
Download or read book Enzymes in Synthetic Organic Chemistry written by Chi-Huey Wong and published by Elsevier. This book was released on 1994-07 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the recent development in enzymatic organic synthesis, this text focuses on the use of isolated enzymes. It includes a discussion of the characteristics of enzymes as catalysts and different types of chemical transformations.
Author :
Publisher : Academic Press
ISBN 13 : 0123744075
Total Pages : 4072 pages
Book Rating : 4.1/5 (237 download)
Download or read book Encyclopedia of Dairy Sciences written by and published by Academic Press. This book was released on 2011-03-25 with total page 4072 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dairy Science, Four Volume Set includes the study of milk and milk-derived food products, examining the biological, chemical, physical, and microbiological aspects of milk itself as well as the technological (processing) aspects of the transformation of milk into its various consumer products, including beverages, fermented products, concentrated and dried products, butter and ice cream. This new edition includes information on the possible impact of genetic modification of dairy animals, safety concerns of raw milk and raw milk products, peptides in milk, dairy-based allergies, packaging and shelf-life and other topics of importance and interest to those in dairy research and industry. Fully reviewed, revised and updated with the latest developments in Dairy Science Full color inserts in each volume illustrate key concepts Extended index for easily locating information
Author : Sergio Riva
Publisher : John Wiley & Sons
ISBN 13 : 3527682511
Total Pages : 587 pages
Book Rating : 4.5/5 (276 download)
Download or read book Cascade Biocatalysis written by Sergio Riva and published by John Wiley & Sons. This book was released on 2014-06-23 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: This ready reference presents environmentally friendly and stereoselective methods of modern biocatalysis. The experienced and renowned team of editors have gathered top international authors for this book. They cover such emerging topics as chemoenzymatic methods and multistep enzymatic reactions, while showing how these novel methods and concepts can be used for practical applications. Multidisciplinary topics, including directed evolution, dynamic kinetic resolution, and continuous-flow methodology are also discussed. From the contents: * Directed Evolution of Ligninolytic Oxidoreductases: from Functional Expression to Stabilization and Beyond * New Trends in the In Situ Enzymatic Recycling of NAD(P)(H) Cofactors * Monooxygenase-Catalyzed Redox Cascade Biotransformations * Biocatalytic Redox Cascades Involving w-Transaminases * Multi-Enzyme Systems and Cascade Reactions Involving Cytochrome P450 Monooxygenases * Chemo-Enzymatic Cascade Reactions for the Synthesis of Glycoconjugates * Synergies of Chemistry and Biochemistry for the Production of Beta-Amino Acids * Racemizable Acyl Donors for Enzymatic Dynamic Kinetic Resolution * Stereoselective Hydrolase-Catalyzed Processes in Continuous-Flow Mode * Perspectives on Multienzyme Process Technology * Nitrile Converting Enzymes Involved in Natural and Synthetic Cascade Reactions * Mining Genomes for Nitrilases * Key-Study on the Kinetic Aspects of the In-Situ NHase/AMase Cascade System of M. imperiale Resting Cells for Nitrile Bioconversion * Enzymatic Stereoselective Synthesis of Beta-Amino Acids * New Applications of Transketolase: Cascade Reactions for Assay Development * Aldolases as Catalyst for the Synthesis of Carbohydrates and Analogs * Enzymatic Generation of Sialoconjugate Diversity * Methyltransferases in Biocatalysis * Chemoenzymatic Multistep One-Pot Processes
Author : Wanyi Guan
Publisher : Royal Society of Chemistry
ISBN 13 : 1788011643
Total Pages : 488 pages
Book Rating : 4.7/5 (88 download)
Download or read book Synthetic Glycomes written by Wanyi Guan and published by Royal Society of Chemistry. This book was released on 2019-04-23 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycans play essential roles in diverse biological and etiological processes and their structural complexity endow various functions. The glycome is the entire set of glycans produced by an individual organism. As the glycan microarray emerged, a good amount of knowledge has been obtained in understanding the functions of glycans. However, limited accessibility of glycans is a major obstacle to the functional glycomics study. Although isolation from biology samples provided some structures, the low abundance of glycans obtained and the difficulty in complete structural assignment restricted the subsequent assay. To circumvent this limitation, many synthetic strategies, including chemical, enzymatic and chemo-enzymatic ones have been developed to make libraries of structurally defined complex glycans available. The glycans provided by these techniques combined with high-throughput glycoarray techniques have broadened and deepened our understanding about functional glycomics. The aim of this book is to provide a comprehensive review of the current state of the synthetic glycome and a brief introduction of the application of the synthetic glycome in glycoarray assay. Accordingly, synthetic strategies toward generating glycans with comprehensive structures as well as the glycoarrays to unveil the glycan functions are described in this book.
Author : Stephen Hanessian
Publisher : CRC Press
ISBN 13 : 9780824798024
Total Pages : 668 pages
Book Rating : 4.7/5 (98 download)
Download or read book Preparative Carbohydrate Chemistry written by Stephen Hanessian and published by CRC Press. This book was released on 1997-01-02 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detailing commonly used methods and procedures, this reference discusses the reactions and derivative forms of carbohydrates. Preparative Carbohydrate Chemistry covers the formation, cleavage, and reactions of derivatives and illustrates bond-forming reactions of SN2 types, free radicals, chain extensions, and branching. The contents include: sugar derivatives; selected reactions in carbohydrate chemistry; chemical synthesis of oligosaccharides and O-and N -glycosyl compounds; enzymatic synthesis of sialic acid, KDO, and related deoxyulosonic acids, and of oligosaccharides; synthesis of -glycosyl compounds; carbocycles from carbohydrates; and total synthesis of sugars from non-sugars. This authoritative reference offers relevant chapters on reactions and derivative forms of carbohydrates, including commonly used methods as well as new experimental procedures. It also contains insightful chapter commentaries and succinct topic histories.
Author : Ashok Pandey
Publisher : Springer Science & Business Media
ISBN 13 : 9780387292946
Total Pages : 774 pages
Book Rating : 4.2/5 (929 download)
Download or read book Enzyme Technology written by Ashok Pandey and published by Springer Science & Business Media. This book was released on 2006-04-28 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description
Author : Amélia Pilar Rauter
Publisher : Royal Society of Chemistry
ISBN 13 : 1839164530
Total Pages : 713 pages
Book Rating : 4.8/5 (391 download)
Download or read book Carbohydrate Chemistry written by Amélia Pilar Rauter and published by Royal Society of Chemistry. This book was released on 2021-12-15 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: In many fields, most notably medicine and molecular biology, the understanding of the structure and function of carbohydrates and glycoconjugates remains vital. This new volume contains critical reviews covering the latest findings in both chemical and biological sciences, and demonstrates the interdisciplinary nature of modern carbohydrate research. This book addresses diverse applications that continue to be major challenges for carbohydrate chemists. The book starts with a review of Gérard Descotes contribution to the field as a pioneer of French modern carbohydrate chemistry. Green nanocatalytic oxidation of free sugars, photosensitive glycomacrocycles, the application of disaccharides in supramolecular chemistry, recent advances in the radiation chemistry of polysaccharides, and the cell wall pectic rhamnogalacturonan II, an enigma in plant glycobiology are just some of the diverse topics presented in Volume 45. This set of reports will certainly benefit any researcher who wishes to learn about the latest developments in the carbohydrate field.
Author : Adrie J.J. Straathof
Publisher : CRC Press
ISBN 13 : 9780203305638
Total Pages : 492 pages
Book Rating : 4.3/5 (56 download)
Download or read book Applied Biocatalysis written by Adrie J.J. Straathof and published by CRC Press. This book was released on 2003-09-02 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the essential steps in the development of biocatalytic processes from concept to completion. It is a carefully integrated text which combines the fundamentals of biocatalysis with technological experience and in-depth commercial case studies. The book starts with an introductory look at the characteristics and present applications of biocatalysts, followed by more detailed overviews of these areas.
Author : Sarah Irène Bonnet
Publisher : Frontiers Media SA
ISBN 13 : 2889455424
Total Pages : 543 pages
Book Rating : 4.8/5 (894 download)
Download or read book Tick-Host-Pathogen Interactions written by Sarah Irène Bonnet and published by Frontiers Media SA. This book was released on 2018-08-24 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Besides causing direct damage associated with blood feeding and in some cases through the excretion of toxins with their saliva, the main relevance of ticks lies in the wide variety of pathogens that they can transmit, including viruses, bacteria, protozoa and helminths. Owing to socioeconomic and environmental changes, tick distribution is changing with incursions of ticks and tick-borne diseases occurring in different regions of the world when the widespread deployment of chemical acaricides and repellents has led to the selection of resistance in multiple populations of ticks. New approaches that are environmentally sustainable and that provide broad protection against current and future tick-borne pathogen (TBP) are thus urgently needed. Such development, however, requires improved understanding of factors resulting in vector competence and tick-host-pathogen interactions. This Research Topic provides an overview of known molecular tick-host-pathogen interactions for a number of TBPs and highlights how this knowledge can contribute to novel control and prevention strategies for tick-borne diseases.
Author : Kalidas Shetty
Publisher : CRC Press
ISBN 13 : 1420007726
Total Pages : 672 pages
Book Rating : 4.4/5 (2 download)
Download or read book Functional Foods and Biotechnology written by Kalidas Shetty and published by CRC Press. This book was released on 2006-09-28 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Foods and Biotechnology focuses the information from the recently published Food Biotechnology to illuminate the role of biochemical processing in the improvement of functional foods and the increase of nutrient value. Applying scientific concepts, the text explores the design of functional food ingredients, the bio-mobilization of major nutrients, and the use of specific phenolic metabolites in disease prevention. Specialty topics include oxidation and disease, antibodies from eggs, phytochemicals as antimicrobials, and passive immune improvement with pro- and pre-biotics. The text provides key emerging techniques for improving food production and processing, enhancing food safety and quality, and increasing nutritional values a
