Chemistry and Biochemistry of B12

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780471253907
Total Pages : 960 pages
Book Rating : 4.2/5 (539 download)

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Book Synopsis Chemistry and Biochemistry of B12 by : Ruma Banerjee

Download or read book Chemistry and Biochemistry of B12 written by Ruma Banerjee and published by John Wiley & Sons. This book was released on 1999-11-03 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Definitive New Reference for the Latest Advances in B_12 Chemistry and Biochemistry Over the past decade, the field of B_12 research has been revolutionized by such major breakthroughs as the unraveling of the entire biosynthetic pathway for this important vitamin. This comprehensive compendium surveys the wealth of information that has accumulated, covering in one volume virtually all aspects of the field-from physical and inorganic chemistry to enzymology, microbiology, medicine, and diagnostic and therapeutic applications. Edited by Dr. Ruma Banerjee, a highly respected and active member of the B_12 community, this work provides B_12 researchers with a dependable and up-to-date reference on the subject. Leading authorities from five continents explore such new areas as the structural biology of B_12-dependent enzymes, free-radical-mediated reaction mechanisms, biosynthesis, and much more. The role of B_12 in nutrition and disease, and B_12 transport, are also thoroughly examined. Complete with color illustrations and extensive references, Chemistry and Biochemistry of B_12 is a one-of-a-kind resource for biochemists, biophysicists, spectroscopists, microbiologists, molecular biologists, and anyone with an interest in "nature's most beautiful cofactor."

Comprehensive B12

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Publisher : Walter de Gruyter
ISBN 13 : 3110844796
Total Pages : 433 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Comprehensive B12 by : Zenon Schneider

Download or read book Comprehensive B12 written by Zenon Schneider and published by Walter de Gruyter. This book was released on 2011-11-14 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Vitamin B 12 and B 12-Proteins

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527612181
Total Pages : 559 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Vitamin B 12 and B 12-Proteins by : Bernhard Kräutler

Download or read book Vitamin B 12 and B 12-Proteins written by Bernhard Kräutler and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely and topical book reviews the important developments in the 'B12-field' with regard to biological, chemical, pharmaceutical and medicinal aspects. In over 30 chapters the approx. 100 internationally renowned authors give deeper insight into the prospering research activites around B12. This book is a must for everybody who works with or on vitamins and porphyrine (-like) ring systems. Topics of particular interest include: Biosynthesis of Vitamin B12; B12-catalyzed enzymatic reactions and their mechanisms; structural B12-chemistry; reactivity of B12 and B12-models; structure and function of B12-proteins; metabolic transport and storage of B12; pathological effects of B12-deficiency.

Vitamin B12

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Author :
Publisher : Academic Press
ISBN 13 : 0323992242
Total Pages : 524 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Vitamin B12 by : Gerald Litwack

Download or read book Vitamin B12 written by Gerald Litwack and published by Academic Press. This book was released on 2022-03-23 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamin B12, Volume 119 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Vitamins and Hormones series Updated release includes the latest information on Vitamin B12

Molecular Modelling of Vitamin B12 and Its Analogues

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Author :
Publisher : CRC Press
ISBN 13 : 1000452301
Total Pages : 177 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Molecular Modelling of Vitamin B12 and Its Analogues by : Penny Govender

Download or read book Molecular Modelling of Vitamin B12 and Its Analogues written by Penny Govender and published by CRC Press. This book was released on 2021-09-23 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, the chemistry of vitamin B12 and its derivatives has been investigated for their inherent eco-friendly and nontoxic nature. This vitamin, also known as cobalamin, is an organic complex that contains a cobalt ion in its structure. Its derivatives are vital bio-inorganic cofactors and possess complex and rich photolytic properties, facilitated by their excited states. This book compiles and details cutting-edge research in the application of vitamin B12 as an environmentally benign catalyst for several organic reactions. It discusses the recent advances and current understanding of the photolytic properties of vitamin B12 derivatives from the perspective of the density functional theory (DFT). The book is of interest for anyone involved in nanotechnology, macromolecular science, cancer, and drug-delivery research.

Coenzyme B12 Enzymes Part B

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Publisher : Academic Press
ISBN 13 : 0323955584
Total Pages : 386 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Coenzyme B12 Enzymes Part B by :

Download or read book Coenzyme B12 Enzymes Part B written by and published by Academic Press. This book was released on 2022-05-27 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coenzyme B12 Enzymes, Part B, Volume 169 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on Structural characterization of cobalamin-dependent radical SAM methylases, Purification and characterization of sequential cobalamin-dependent radical SAM methylases ThnK and TokK in -lactam antibiotic biosynthesis, Characterization of the cobalamin-dependent radical S-adenosyl-L-methionine enzyme C-methyltransferase Fom3 in fosfomycin biosynthesis, Studies of OxsB and GenK, two B12-dependent radical SAM enzymes involved in natural product biosynthesis, Purification and structural elucidation of the cobalamin-dependent radical SAM enzyme OxsB, and more. Other chapters discuss Methods for studying the mechanisms of B12 enzymes, Computational investigations of B12 dependent enzymatic reactions, Using kinetic isotope effects to probe the mechanisms of adenosylcobalamin-dependent enzymes, Steady-state and pre-steady state kinetic analysis of ornithine 4,5-aminomutase, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology series Includes the latest information on B12 Enzymes

Coenzyme B12 Enzymes Part A

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Publisher : Academic Press
ISBN 13 : 0323915922
Total Pages : 392 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Coenzyme B12 Enzymes Part A by :

Download or read book Coenzyme B12 Enzymes Part A written by and published by Academic Press. This book was released on 2022-05-17 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: B12 Enzyme, Volume 667 in the Methods in Enzymology serial, highlights new advances in the field with this new volume presenting timely, interesting chapters, including Part I: B12 Biosynthesis and B12 Chaperones, Probing the preference and regioselectivity of lower ligand activation and its role in cobamide diversity, Biosynthesis of corrinoids, The human B12 trafficking chaperones: CblC, CblD and ATR, A method for the efficient adenosylation of corrinoids, Production, purification and liposome reconstitution of cobamide synthase, Extraction and Purification of Cobamides from Bacterial Cultures, Part II: The many faces of B12-dependent enzyme reactions, Methylcobalamin-dependent methionine synthase, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology serials Includes the latest information on B12 Enzymes

Laboratory Assessment of Vitamin Status

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Publisher : Academic Press
ISBN 13 : 0128130512
Total Pages : 340 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Laboratory Assessment of Vitamin Status by : Dominic J. Harrington

Download or read book Laboratory Assessment of Vitamin Status written by Dominic J. Harrington and published by Academic Press. This book was released on 2018-11-28 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Assessment of Vitamin Status provides a comprehensive understanding of the limitations of commonly used approaches used for the evaluation of vitamin status, reducing harm in the general health setting. It outlines the application of ‘Best Practice’ approaches to the evaluation of vitamin status, giving physicians and other healthcare professionals the opportunity to make evidence-based interventions. Nearly every metabolic and developmental pathway in the human body has a dependency on at least one micronutrient. Currently, the clinical utility of approaches taken by laboratories for the assessment of vitamin status is generally poorly understood, missing the opportunity to diagnosis vitamin deficiencies. This essential reference gives clinical and biomedical scientists an understanding of the limitations of commonly used approaches to the evaluation of vitamin status in the general health setting through change in practice. Nutritionists and dietitians gain an understanding of more sophisticated markers of vitamin status. Describes specialist assays in sufficient detail to enable laboratories to replicate what is being performed by expert groups Provides detailed information that supports laboratories in the setting up of methods for the evaluation of vitamin status Informs laboratories looking for third party providers of specialist investigations Provides an essential overview of reference ranges for each vitamin

The Chemical Biology of Human Vitamins

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1788014642
Total Pages : 462 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis The Chemical Biology of Human Vitamins by : Christopher Walsh

Download or read book The Chemical Biology of Human Vitamins written by Christopher Walsh and published by Royal Society of Chemistry. This book was released on 2019 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a thorough chemocentric view on the key small molecules of life, the human vitamins and their active coenzyme forms.

Vitamin C

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Publisher : Royal Society of Chemistry
ISBN 13 : 1847552307
Total Pages : 174 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Vitamin C by : M B Davies

Download or read book Vitamin C written by M B Davies and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamin C is the first book to cover the history, chemistry, biochemistry, and medical importance of vitamin C and is the first to provide an in-depth, interdisciplinary study of this essential and fascinating compound. The book provides a comprehensive and systematic account of the vitamin C story, fully surveying the history of scurvy and how its cure led to the suggestion, discovery, and isolation of the vitamin, later named L-ascorbic acid. It describes in detail the vitamin's structure determination, synthesis and manufacture, and its oxidation products, derivatives and related compounds. Its key biochemical roles are fully categorized and explained, and the medical importance of the vitamin, including the recent use of so-called megadoses, is thoroughly discussed. Vitamin C will be of interest to a very wide readership and will provide useful background information and inspiration for students at various levels. It will also be relevant to the interested chemist or lay person, as well as those carrying out research in this area.

Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527337342
Total Pages : 580 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants by : Erick J. Vandamme

Download or read book Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants written by Erick J. Vandamme and published by John Wiley & Sons. This book was released on 2016-04-25 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamins are a group of physiologically very important, chemically quite complex organic compounds, that are essential for humans and animals. Some vitamins and other growth factors behave as antioxidants, while some can be considered as biopigments. As their chemical synthesis is laborious, their biotechnology-based synthesis and production via microbial fermentation has gained substantial interest within the last decades. Recent progress in microbial genetics and in metabolic engineering and implementation of innovative bioprocess technology has led to a biotechnology-based industrial production of many vitamins and related compounds. Divided into three sections, this volume covers: 1. water-soluble vitamins 2. fat-soluble vitamin compounds and 3. other growth factors, biopigments, and antioxidants. They are all reviewed systematically: from natural occurrence and assays, via biosynthesis, strain development, to industrially-employed biotechnological syntheses and applications.

Vitamin C

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 9780851863337
Total Pages : 182 pages
Book Rating : 4.8/5 (633 download)

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Book Synopsis Vitamin C by : Michael B. Davies

Download or read book Vitamin C written by Michael B. Davies and published by Royal Society of Chemistry. This book was released on 1991 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides an in-depth, interdisciplinary study of the history, chemistry, biochemistry and medical importance of Vitamin C. Of interest to school, polytechnic and university students and chemists or lay persons carrying out research in this area.

The Vitamins

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Publisher : Academic Press
ISBN 13 : 1483222020
Total Pages : 693 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis The Vitamins by : W. H. Sebrell

Download or read book The Vitamins written by W. H. Sebrell and published by Academic Press. This book was released on 2013-10-22 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vitamins: Chemistry, Physiology, Pathology, Volume I emphasizes the chemical, physiological, and pathological aspects of vitamins. This volume contains four chapters. Each chapter discusses the vitamin's nomenclature, industrial preparation, biogenesis, occurrence in foods, effects of its deficiency, and metabolism. Other general topics covered in each chapter include the vitamin's specificity of action, toxicity, pharmacology, detoxification, requirements, and therapeutic activity. This volume evaluates vitamins such as vitamins A, carotenes, ascorbic acid, vitamin B12, and biotin. This book will be of value to nutritionists, dieticians, food scientists, technologists, and researchers.

Vitamin B12

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Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3111510824
Total Pages : 1240 pages
Book Rating : 4.1/5 (115 download)

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Book Synopsis Vitamin B12 by : B. Zagalak

Download or read book Vitamin B12 written by B. Zagalak and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-10-08 with total page 1240 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Vitamin B12".

Biosynthesis

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Publisher : Springer Science & Business Media
ISBN 13 : 3540695427
Total Pages : 214 pages
Book Rating : 4.5/5 (46 download)

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Book Synopsis Biosynthesis by : F.J. Leeper

Download or read book Biosynthesis written by F.J. Leeper and published by Springer Science & Business Media. This book was released on 2003-09-05 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concerned with discovering the chemical pathways of biosynthesis, this book devotes four chapters to the use of isotopes in biosynthetic research and the biosynthesis of enzyme cofactors and vitamin B12 and of reduced polyketides such as erythromycin. The topics covered demonstrate the revolution that has occurred in biosynthetic studies with the advent of gene cloning and overexpression. Yet the book also shows that the more classical approach to biosynthetic studies must go hand in hand with these new techniques.

The Porphyrin Handbook

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Publisher : Elsevier
ISBN 13 : 0080923852
Total Pages : 321 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis The Porphyrin Handbook by : Roger Guilard

Download or read book The Porphyrin Handbook written by Roger Guilard and published by Elsevier. This book was released on 2012-12-02 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Porphyrin Handbook, Volume 11: Bioinorganic and Bioorganic Chemistry presents the fundamental aspects of the synthesis, structure, chemistry, and spectroscopy of phthalocyanines. This book discusses the biology and medical implications of porphyrin systems. Organized into seven chapters, this volume begins with an overview of the design, synthesis, and study of the structural and functional models of heme/copper terminal oxidases. This text then examines the proteins containing iron-protoporphyrin IX (heme), which play key roles in photosynthesis and respiration. Other chapters consider the syntheses of chiral porphyrin derivatives and summarize the uses of such compounds in enantioselective control. This book discusses as well the reactivity and synthesis of synthetic carbine metalloporphyrins. The final chapter deals with the B12-coenzymes, which is the most complex and physiologically important organometallic enzymatic reactions that directly depend on the reactivity of metal coordinated organic ligands. This book is a valuable resource for research scientists, clinicians, and engineers.

Bioorganometallic Chemistry

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Publisher :
ISBN 13 :
Total Pages : 240 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Bioorganometallic Chemistry by : G. Simonneaux

Download or read book Bioorganometallic Chemistry written by G. Simonneaux and published by . This book was released on 2006-05-23 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioorganometallic Chemistry has become a mature area of science and is comprehensively covered by leading experts in this book. Research in this rapidly developing transdisciplinary field is having profound influence on other areas of scientific investigation, ranging from catalytic organic synthesis to biology, medicine and material science. This book provides a balanced view of this rapidly developing and promising subject.