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Chemistry And Applications Of Benzimidazole And Its Derivatives
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Book Synopsis Chemistry and Applications of Benzimidazole and its Derivatives by : Maria Marinescu
Download or read book Chemistry and Applications of Benzimidazole and its Derivatives written by Maria Marinescu and published by BoD – Books on Demand. This book was released on 2019-10-02 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finding new strategies for synthesizing benzimidazole derivatives and functionalizing the benzimidazole core has proved to be important due to the compound's various applications in medicine, chemistry, and other areas. The multitude of benzimidazole derivatives marketed as drugs has led to intensive research in the field for the discovery of new biologically active structures. The general applications of benzimidazole derivatives in materials chemistry, electronics, technology, dyes, pigments, and agriculture open up new research horizons. This book guides the rational design of benzimidazole derivatives synthesis with certain applications. Chapters cover such topics as therapeutic use of benzimidazole in conditions like diabetes, viruses, and parasitic diseases; X-ray crystal structure of selected benzimidazole derivatives; benzimidazole compounds for cancer therapy; and others.
Book Synopsis Benzimidazole by : Aksel A. Vestergaard
Download or read book Benzimidazole written by Aksel A. Vestergaard and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Benzimidazole: Preparation and Applications first defines the structure, physical and chemical properties of the benzimidazole compound class. Further conventional and alternative synthesis methods and important reactions of these compound derivatives are illustrated with examples. The authors provide an overview of benzimidazole-based synthetic medicine and their significant applications in treating various ailments. The chemical reactions of benzimidazole with other heterocyclic compounds/chemical reagents produce a lot of new substituted molecules, which have potential pharmaceutical applications. A literature review is presented focusing on the synthesis of chiral compounds and their subsequent applications as therapeutic compounds in order to better evaluate the results so far. Additionally, the authors discuss how nenzimidazole derivatives play a vital role in organic light emitting diodes as emissive materials, host materials, electron transport materials, hole blocking materials, etc., and have pharmaceutical applications such as antimicrobial, antihypertensive, anti-HIV and anticancer. Following this, this collection examines classes of potential chemosensors possessing benzimidazole moieties which are capable of both visual and optical estimation of target analytes over a broad concentration range and without interference of contemporary analytes. Important methodologies used for the synthesis of variedly substituted benzimidazoles are presented along with their multi-target therapeutic uses. The latest research on anti-tumor and antimicrobial benzimidazole compounds, as well as structure-activity correlations, drug design, clinical and preclinical studies is also presented. Benzimidazole-based polymers with various architecture and copolymers are discussed with a variation of properties such as mechanical, thermal stability, thermo-oxidative stability and enhanced performance. The penultimate chapter covers a critical analysis of the recent developments in benzimidazole framework research and the future scope of benzimidazole framework in ligand designing. In closing, the synthesis and biological properties of coordination compounds containing benzimidazole derivatives are presented and discussed.
Book Synopsis Organic Corrosion Inhibitors by : Chandrabhan Verma
Download or read book Organic Corrosion Inhibitors written by Chandrabhan Verma and published by John Wiley & Sons. This book was released on 2021-12-02 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of organic corrosion inhibitors used in modern industrial platforms, including current developments in the design of promising classes of organic corrosion inhibitors Corrosion is the cause of significant economic and safety-related problems that span across industries and applications, including production and processing operations, transportation and public utilities infrastructure, and oil and gas exploration. The use of organic corrosion inhibitors is a simple and cost-effective method for protecting processes, machinery, and materials while remaining environmentally acceptable. Organic Corrosion Inhibitors: Synthesis, Characterization, Mechanism, and Applications provides up-to-date coverage of all aspects of organic corrosion inhibitors, including their fundamental characteristics, synthesis, characterization, inhibition mechanism, and industrial applications. Divided into five sections, the text first covers the basics of corrosion and prevention, experimental and computational testing, and the differences between organic and inorganic corrosion inhibitors. The next section describes various heterocyclic and non-heterocyclic corrosion inhibitors, followed by discussion of the corrosion inhibition characteristics of carbohydrates, amino acids, and other organic green corrosion inhibitors. The final two sections examine the corrosion inhibition properties of carbon nanotubes and graphene oxide, and review the application of natural and synthetic polymers as corrosion inhibitors. Featuring contributions by leading researchers and scientists from academia and industry, this authoritative volume: Discusses the latest developments and issues in the area of corrosion inhibition, including manufacturing challenges and new industrial applications Explores the development and implementation of environmentally-friendly alternatives to traditional toxic corrosion inhibitors Covers both established and emerging classes of corrosion inhibitors as well as future research directions Describes the anticorrosive mechanisms and effects of acyclic, cyclic, natural, and synthetic corrosion inhibitors Offering an interdisciplinary approach to the subject, Organic Corrosion Inhibitors: Synthesis, Characterization, Mechanism, and Applications is essential reading for chemists, chemical engineers, researchers, industry professionals, and advanced students working in fields such as corrosion inhibitors, corrosion engineering, materials science, and applied chemistry.
Download or read book Quinoxalines written by Vakhid A. Mamedov and published by Springer. This book was released on 2016-04-26 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the fundamental aspects of quinoxaline chemistry: synthesis, reactions, mechanisms, structure, properties, and uses. The first four chapters present a survey of the developments in quinoxaline chemistry since the publication of the monograph on “Condensed Pyrazines” by Cheeseman and Cookson in 1979. These chapters give comprehensive coverage of all the methods of the synthesis of quinoxalines and the important quinoxaline-containing ring systems such as thiazolo[3,4-a]-, pyrrolo[1,2-a]-, and imidazo[1,5-a]quinoxalines. Chapter five describes many new methods for the construction of quinoxaline macrocycles, which are important in applications such as optical devices and materials. The final chapter reviews all previously known rearrangements of heterocyclic systems that lead to benzimidazole derivatives. Mamedov critically analyses these transformations to reveal a novel acid-catalyzed rearrangement of quinoxalinones giving 2-heteroarylbenzimidazoles and 1-heteroarylbenzimidazolones in the presence of nucleophilic reactants (MAMEDOV Heterocycle Rearrangement). This book is of interest to researchers in the fields of heterocyclic and synthetic organic chemistry.
Book Synopsis Handbook of Green Chemistry by : Paul T. Anastas
Download or read book Handbook of Green Chemistry written by Paul T. Anastas and published by . This book was released on 2013 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Green Approaches in Medicinal Chemistry for Sustainable Drug Design by : Bimal Banik
Download or read book Green Approaches in Medicinal Chemistry for Sustainable Drug Design written by Bimal Banik and published by Elsevier. This book was released on 2020-03-27 with total page 1046 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6. - Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability - Reflects on techniques for a broad range of compounds and materials - Highlights sustainable and green chemistry pathways for molecular synthesis
Book Synopsis Principles of Chemical Nomenclature by : G. J. Leigh
Download or read book Principles of Chemical Nomenclature written by G. J. Leigh and published by Royal Society of Chemistry. This book was released on 2011 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at pre-university and undergraduate students, this volume surveys the current IUPAC nomenclature recommendations in organic, inorganic and macromolecular chemistry.
Book Synopsis Textbook of Organic Medicinal and Pharmaceutical Chemistry by : Charles Owens Wilson
Download or read book Textbook of Organic Medicinal and Pharmaceutical Chemistry written by Charles Owens Wilson and published by Lippincott Williams & Wilkins. This book was released on 1977 with total page 1150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Structure and Activity Relationship of Coumarin Derivatives by : Santhosh Penta
Download or read book Advances in Structure and Activity Relationship of Coumarin Derivatives written by Santhosh Penta and published by Academic Press. This book was released on 2015-08-07 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Structure and Activity Relationship of Coumarin Derivatives covers the structural behavior of various coumarin derivatives for various potential pharmaceutical applications. Based on substitution targeted for active sites, the book takes a rational approach for designing new and specific potent drugs, optimizing existing ones, and developing novel reactions. This focused primer describes the chemical structure and activity of coumarin derivatives to explore the effects of different substituents at specific positions, and their properties for effective bioactivity. - Accessible and current coverage of coumarin derivatives from structure to potential applications - Application of SAR technology to predict bioactivity of the derivatives based on its chemical structure - Information for researchers in medicinal chemistry, pharmaceutical sciences, and related fields
Book Synopsis Contrast Agents III by : Roger Alberto
Download or read book Contrast Agents III written by Roger Alberto and published by Springer Science & Business Media. This book was released on 2005-02-10 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: with contributions by numerous experts
Book Synopsis Chemistry of 1,2,3-triazoles by : Wim Dehaen
Download or read book Chemistry of 1,2,3-triazoles written by Wim Dehaen and published by Springer. This book was released on 2014-10-20 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.
Book Synopsis Approaches to Design and Synthesis of Antiparasitic Drugs by : N. Anand
Download or read book Approaches to Design and Synthesis of Antiparasitic Drugs written by N. Anand and published by Elsevier. This book was released on 1997-07-10 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinical and veterinary practice. The book will be useful to a wide spectrum of readers: students embarking on a research career in parasitic chemotherapy, clinicians (and veterinarians) and clinical pharmacologists desiring detailed information about the drugs currently in use, and pharmaceutical technologists wanting to update their knowledge of the methods of manufacture.
Book Synopsis Quinazolinone and Quinazoline Derivatives by : Ali Gamal Al-kaf
Download or read book Quinazolinone and Quinazoline Derivatives written by Ali Gamal Al-kaf and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Organic Chemistry of Drug Synthesis, Volume 7 by : Daniel Lednicer
Download or read book The Organic Chemistry of Drug Synthesis, Volume 7 written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2007-12-14 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The classic reference on the synthesis of medicinal agents -- now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6. Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.
Book Synopsis Heterocyclic Compounds by : Kristian Nylund
Download or read book Heterocyclic Compounds written by Kristian Nylund and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocyclic compounds are organic compounds containing at least one atom of carbon, and at least one element other than carbon, such as sulphur, oxygen or nitrogen within a ring structure. These structures may comprise either simple aromatic rings or non-aromatic rings. Some examples are pyridine (C5H5N), pyrimidine (C4H4N2) and dioxane (C4H8O2). Many heterocyclic compounds, including some amines, are carcinogenic. This book details the proposed mechanisms of Gewald-like reactions and the wide scope of substituted 2-aminothiophenes for real life applications. Literary information about synthesis methods, structure, physical-chemical and biological properties is summarised, and also information about conversion of adamantyl-1 and adamantyl-2 imidazole and benzimidazole derivatives is given. In addition, 3-acetylindole derivatives have been in the centre of attention of researchers over many years due to the high practical value of these compounds. This book presents a survey of the literature on 3-acetylindoles chemistry and provides useful and up-to-date data for medicinal chemists.
Book Synopsis The Chemistry of Heterocycles by : Vishnu Ji Ram
Download or read book The Chemistry of Heterocycles written by Vishnu Ji Ram and published by Elsevier. This book was released on 2019-06-05 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocycles are ubiquitously present in nature and occupy a unique place in organic chemistry as they are part of the DNA and haemoglobin that make life possible. The Chemistry of Heterocycles covers an introduction to the topic, followed by a chapter on the nomenclature of all classes of isolated, fused and polycyclic heterocycles. The third chapter delineates the highly strained three membered N,O and S containing aromatic and non-aromatic heterocycles with one and more than one similar and dissimilar heteroatom. The four-membered heterocycles are abundantly present in various natural and synthetic products of pharmacological importance. This chapter describes the natural abundance, synthesis, chemical reactivity, structural features and their medicinal importance. This class of compounds are present as sub-structures in penicillin and cytotoxic Taxol. Lastly, a chapter on the natural abundance, synthesis, chemical reactivity and pharmacological importance of 5-membered heterocycles with N,O,S heteroatom is covered. The chemistry of heterocycles with mixed heteroatom such as, N-S, N-O, N-S etc. is also described. - Gives in-depth, clear information about various systems of nomenclature along with widely acceptable IUPAC system for naming various classes of heterocycles - Provides complete information about natural occurrences, synthesis, chemical reactivity, pharmacological importance of heterocycles and their application in material science - Highly relevant for graduate students and researchers, providing updated information about various isolated and fused N,O and,S containing heterocycles
Book Synopsis Manganese Catalysis in Organic Synthesis by : Jean-Baptiste Sortais
Download or read book Manganese Catalysis in Organic Synthesis written by Jean-Baptiste Sortais and published by John Wiley & Sons. This book was released on 2021-12-20 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Manganese Catalysis in Organic Synthesis A must-read reference for anyone interested in catalyst design and sustainable organic synthesis In Manganese Catalysis in Organic Synthesis, distinguished researcher Jean-Baptiste Sortais delivers an insightful and robust overview of the use of manganese in homogenous catalysis. The editor includes papers from authoritative academics describing the organometallic precursors used to develop manganese catalysts and covers critical applications in organic synthesis, including reduction to oxidation reactions, C-C, C-N, C-X bond formation reactions, cross-coupling reactions, C-H bond activation to dihydroxylation and epoxidation reactions. Manganese Catalysis in Organic Synthesis is a practical resource for every organic chemist in academia and industry with an interest in non-noble metal catalysis, organic synthesis, and sustainable chemistry. It is intuitively and clearly organized, covering the most important synthetic procedures using homogenous manganese catalysts. It is also the ideal companion to works like Cobalt Catalysis in Organic Synthesis, Nickel Catalysis in Organic Synthesis, and Iron Complexes in Catalysis. Readers will also enjoy: Thorough introductions to organometallic manganese compounds in organic synthesis and manganese-catalyzed hydrogenation and hydrogen transfer reactions A comprehensive exploration of manganese-catalyzed hydrogen borrowing reactions and dehydrogenative coupling reactions Practical discussions of manganese-catalyzed hydrosilylation and hydroboration reactions and manganese-catalyzed electro- and photocatalysis transformations In-depth examinations of manganese-catalyzed C-H oxygenation reactions and manganese-catalyzed organometallic C-H activation Insightful treatments of manganese-catalyzed cross-coupling processes and manganese(III) acetate mediated cyclizations Perfect for catalytic, organic, and pharmaceutical chemists, Manganese Catalysis in Organic Synthesis deserves a place in the libraries of researchers and professionals interested in catalyst design and sustainable organic synthesis.
