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Chemical And Biological Aspects Of Steroid Conjugation
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Book Synopsis Chemical and Biological Aspects of Steroid Conjugation by : S. Bernstein
Download or read book Chemical and Biological Aspects of Steroid Conjugation written by S. Bernstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a collaborative endeavor by a group of investigators to bring together in a single volume a critical discussion of the major facets of our knowledge, ranging from chemical to clinical aspects, of steroid conjugation. However, the important field of bile acid and bile alcohol conjugation has been discussed only superficially since it was decided arbitrarily to be outside the projected scope of the book. The reader is referred to the companion volume of this book, namely Physical Properties of Steroid Conjugates (by Bernstein, Dusza, and Joseph, Springer-Verlag New York 1968), for complemental information on individual conjugates. The Editors wish to thank Miss Elise Kramer for typing assistance. Also we wish to express our deep appreciation and gratitude to Mrs. Dorothy Budd, our copy-editor, and Mr. J. Joseph for their editorial assistance in making this book possible. SEYMOUR BERNSTEIN Pearl River, N. Y. January, 1970 SAMUEL SOLOMON V11 CONTENTS Preface . . . . VII Nomenclature a, Discussion of Nomenclature System x b, Trivial and Systematic Names. x List of Contributors . . . . . . . . Xl Chemistry: Synthesis and Characterization S. BERNSTEIN, 1. P. DUSZA, and J. P. JOSEPH Enzymological Aspects of Steroid Conjugation A. B. Roy . . . . . . . . . . 74 The Hydrolysis of Steroid Conjugates H. L. BRADLOW . . . . . 131 Isolation of Steroid Conjugates P. K. SITTERI. . . . . . . 182 The Biochemistry of the 3P-Hydroxy-Ll5-Steroid Sulfates K. D. ROBERTS and S. LIEBERMAN 219 Formation, Metabolism, and Transport of Estrogen Conjugates E. DICZFALUSY and M. LEVITZ. . . . . . . . . . . . .
Book Synopsis Chemical and Biological Aspects of Steroid Conjugation by : Samuel Solomon
Download or read book Chemical and Biological Aspects of Steroid Conjugation written by Samuel Solomon and published by [New York] : Springer-Verlag New York. This book was released on 1970 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chemical and Biological Aspects of Steroid Conjugation, Edited by Seymour Bernstein and Samuel Solomon by : Seymour Bernstein
Download or read book Chemical and Biological Aspects of Steroid Conjugation, Edited by Seymour Bernstein and Samuel Solomon written by Seymour Bernstein and published by . This book was released on 1970 with total page 61 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chemistry and Biological Activity of Steroids by : Jorge António Ribeiro Salvador
Download or read book Chemistry and Biological Activity of Steroids written by Jorge António Ribeiro Salvador and published by BoD – Books on Demand. This book was released on 2020-02-26 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: The steroid scaffold continues to be the structural basis of new drugs for a variety of targets and diseases. Indeed, steroids interact with enzymes and receptors in a strikingly specific manner. Chemistry and Biological Activity of Steroids aims to provide an updated overview of recent advances in the medicinal chemistry of steroids. Novel synthetic methods in the steroids field, including steroid biotransformations, new steroids able to tackle steroid receptors, and steroid enzymes with clinical relevance, are critically reviewed in this book. Furthermore, the diverse physiopathological roles of oxysterols and their therapeutic value are also discussed.
Book Synopsis Chemical and Biological Aspects of Steroid Conjunction by : Seymour Bernstein
Download or read book Chemical and Biological Aspects of Steroid Conjunction written by Seymour Bernstein and published by . This book was released on 1970 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Principles of Endocrinology and Hormone Action by : Antonino Belfiore
Download or read book Principles of Endocrinology and Hormone Action written by Antonino Belfiore and published by Springer. This book was released on 2018-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.
Book Synopsis The Biology of Cholesterol and Related Steroids by : N. B. Myant
Download or read book The Biology of Cholesterol and Related Steroids written by N. B. Myant and published by Butterworth-Heinemann. This book was released on 2014-04-24 with total page 925 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biology of Cholesterol and Related Steroids focuses on the study of sterols in relation to living organisms. The publication first takes a look at the analysis of sterols and related steroids and the distribution of sterols and related steroids in nature, as well as the processes of extraction and separation and presence of sterols in plants, fungi, vertebrates, and invertebrates. The text then ponders on biosynthesis of sterols and metabolism of cholesterol. Topics include formation of fatty acid esters of cholesterol, steroid hormones, biosynthetic pathway to sterols, reaction mechanisms, and comparative aspects of sterol synthesis. The manuscript examines the developmental aspects of cholesterol metabolism and sterols in biological membranes. The book also reviews cholesterol synthesis in animal tissues, sterol metabolism in isolated cells, and epidemiology of the plasma cholesterol. Discussions focus on selection of statistical populations, genetic influences, regulation of sterol synthesis, general aspects of sterol metabolism, and removal of cell cholesterol in vivo. The publication is a dependable source of data for biochemists and readers interested in the biology of cholesterol and steroids.
Book Synopsis Terpenoids and Steroids by : Karl Howard Overton
Download or read book Terpenoids and Steroids written by Karl Howard Overton and published by Royal Society of Chemistry. This book was released on 1972 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 90 years The Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Book Synopsis Enzymatic Basis of Detoxication Volume 2 by : William B. Jakoby
Download or read book Enzymatic Basis of Detoxication Volume 2 written by William B. Jakoby and published by Elsevier. This book was released on 2012-12-02 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzymatic Basis of Detoxication, Volume II, reviews the state of knowledge on foreign compound metabolism at the level of what specific enzymes can do. The book attempts to provide a holistic view of the information gleaned from work with specific, purified enzymes encompassing as many mammalian sources as have been studied. The book is organized into two parts. Part I on conjugation reactions and related systems includes studies on the properties of glucuronide formation; the physiological function, assay, and purificatgion of function of bilirubin-glucuronoside glucuronosyltransferase; the roles of N- and O-methylation reactions and glutathione transferases in detoxication; and amino acid conjugation. Part II presents studies on hydrolytic systems, covering the role of epoxide hydrolase, carboxylesterases, and amidases in detoxication and the regulatory effects of these enzymes. This book provides pharmacologists and toxicologists with the biochemical view of detoxication, and biochemists with the corresponding pharmacological and toxicological aspects.
Author :Library of Congress. Copyright Office Publisher :Copyright Office, Library of Congress ISBN 13 : Total Pages :1938 pages Book Rating :4.F/5 ( download)
Book Synopsis Catalog of Copyright Entries. Third Series by : Library of Congress. Copyright Office
Download or read book Catalog of Copyright Entries. Third Series written by Library of Congress. Copyright Office and published by Copyright Office, Library of Congress. This book was released on 1973 with total page 1938 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Vitamins and Hormones written by and published by Academic Press. This book was released on 1983-01-07 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamins and Hormones
Book Synopsis Modern Methods of Steroid Analysis by : Erich Heftmann
Download or read book Modern Methods of Steroid Analysis written by Erich Heftmann and published by Elsevier. This book was released on 2012-12-02 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Methods of Steroid Analysis reviews modern methods of steroid analysis such as liquid column chromatography, mass spectrometry, and gas chromatography. Topics covered include qualitative and quantitative analysis of plant sterols by gas-liquid chromatography; Raman spectroscopy of steroids; nuclear magnetic resonance; and applications of lanthanide shift reagents. A computerized method for rapid comparison and retrieval of infrared spectral data is also described. This volume is comprised of 22 chapters and begins with an analysis of hormonal steroids using liquid column chromatography, followed by a discussion on the separation of insect molting hormones using high-pressure liquid chromatography. The reader is methodically introduced to the application of gradient elution and thin-layer chromatography to the analysis of corticosteroids and 17-ketosteroids, as well as some aspects of mass spectrometry in steroid analysis. Subsequent chapters explore other methods such as optical rotatory dispersion and circular dichroism, along with radioisotope techniques. In particular, the radioimmunoassay of plasma steroid hormones and plasma aldosterone is considered. This book should be of interest to biochemists.
Book Synopsis Marine Natural Products Chemistry by : D. Faulkner
Download or read book Marine Natural Products Chemistry written by D. Faulkner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the lectures presented at the NATO sponsored conference on "Marine Natural Products" held in Jersey, Channel Islands, U. K., October 12-17, 1976. The intent of the organising committee was to encourage a dialogue between organic chemists who study the metabolites of marine organisms and biolo gists, ecologists, and pharmacologists who study the effects of these metabolites on other organisms. A feature of the conference was the three workshop sessions on chemotaxonomy, applications of marine natural products, and chemical communication. The papers presented at the conference contain a mixture of original research in marine natural products and reviews of some of the more important subjects. The biologists were asked to present papers which could initiate new directions for marine natural products research. Their contributions to the meeting were warmly received by the chemists in the audience. We hope that this volume contains not only past and present research but a suggestion of future research trends. The conference was first suggested by Dr. E. D. Goldberg. The organising committee, Drs. G. Blunden, D. J. Faulkner, W.
Book Synopsis Sulfatases Of Microbial Origin by : Kenneth S. Dodgson
Download or read book Sulfatases Of Microbial Origin written by Kenneth S. Dodgson and published by CRC Press. This book was released on 2018-05-04 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the succeeding pages the authors have collated scattered information about individual sulfatases and have endeavoured to indicate their physiological roles within the microorganism, the ways in which their synthesis is subject to genetic and physiological control, and their participation in natural processes such as the recycling sulfur. The authors have also attempted, for the first time, to discuss at length the mechanisms of action of some of the enzymes in relation to current knowledge about the nonenzymic hydrolysis of various types of sulfate ester. Although primarily directed towards those people interested in biochemistry and enzymology of microorganisms, it is the authors belief that there will be much in the book that will be of interest to worker in the mammalian field.
Download or read book Endocrinology Index written by and published by . This book was released on 1971-07 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Sulfation of Drugs & Related Compounds by : Gerard J. Mulder
Download or read book Sulfation of Drugs & Related Compounds written by Gerard J. Mulder and published by CRC Press. This book was released on 2020-04-22 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1981, this book is an in-depth exploration into the sulfation process in the manufacturing of pharmaceuticals. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of Pharmacology, and other practitioners in their respective fields.
Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1965 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt:
