Characterization of Tear Breakup and Its Sensory Responses

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Publisher :
ISBN 13 :
Total Pages : 205 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Characterization of Tear Breakup and Its Sensory Responses by : Deborah Awisi-Gyau

Download or read book Characterization of Tear Breakup and Its Sensory Responses written by Deborah Awisi-Gyau and published by . This book was released on 2020 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dry eye disease (DED) affects millions of people in the United States and worldwide. Tear film instability (TFI) and hyperosmolarity have been implicated in the etiology of DED, which is characterized by a loss of homeostasis of the tear film. Theoretically, tear film evaporation is the main factor leading to TFI, resulting in an increased tear film osmolarity and possible "dry spots" when tear film disruption or breakup (TBU) occurs. These adverse conditions in the tear film may damage the ocular surface and stimulate underlying corneal sensory nerves, leading to the symptoms of ocular irritation characteristic of DED. However, the link between the symptoms of DED and TFI remains poorly understood because many highly symptomatic DED patients show little or no ocular surface damage to account for their symptoms. In this thesis, I address this gap in our knowledge by investigating the connection between TFI and the sensory response of the ocular surface epithelium. In the series of experiments described in this thesis, we use a human based method developed in our lab to stimulate TBU and study the formation and progression of TBU. Further, we develop methods to obtain known concentrations of fluorescein and lissamine green, characterize TBU patterns and its impact on corneal sensory thresholds. We hypothesize that TFI can alter the epithelial surface environment by chemical, thermal, and mechanical changes in the tear film, which can stimulate underlying sensory nerves, without clinically observable surface damage. Further, we theorize that repeated TFI and, thus, recurring stimulation of ocular surface sensory neurons leads to altered sensory thresholds and persistent discomfort.

The Lacrimal System

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Publisher : Springer Science & Business Media
ISBN 13 : 0387352678
Total Pages : 293 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis The Lacrimal System by : Adam J. Cohen

Download or read book The Lacrimal System written by Adam J. Cohen and published by Springer Science & Business Media. This book was released on 2006-11-25 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to help Lacrimal surgeons not only avoid their own mistakes, but correct the complications of patients referred to them. Lacrimal surgery is not a part of every ophthalmologist’s daily practice, but every eye care provider refers patients to the occuloplastic specialist who do these procedures. There have been exciting advances in recent years, including the advent of balloon assisted procedures. But, the increase in lasik procedures has led to dry eye as a common complication. This surgical "how to" book shows the general ophthalmologist and occuloplastic specialist how to effectively treat the range of lacrimal disorders.

Investigative Ophthalmology & Visual Science

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Publisher :
ISBN 13 :
Total Pages : 1132 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Investigative Ophthalmology & Visual Science by :

Download or read book Investigative Ophthalmology & Visual Science written by and published by . This book was released on 2009 with total page 1132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Environmental Health Perspectives

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Publisher :
ISBN 13 :
Total Pages : 838 pages
Book Rating : 4.M/5 ( download)

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Book Synopsis Environmental Health Perspectives by :

Download or read book Environmental Health Perspectives written by and published by . This book was released on 1998 with total page 838 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ocular Surface Disorders

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Publisher : JP Medical Ltd
ISBN 13 : 1907816313
Total Pages : 414 pages
Book Rating : 4.9/5 (78 download)

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Book Synopsis Ocular Surface Disorders by : Jose M Benitez-del-Castillo

Download or read book Ocular Surface Disorders written by Jose M Benitez-del-Castillo and published by JP Medical Ltd. This book was released on 2013-11-04 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current knowledge of the epidemiology, clinical expression, pathophysiology and available medical and surgical therapy for ocular surface diseases, providing an invaluable text for ocular surface specialists, general ophthalmologists, optometrists and residents.

Ocular Surface Disease: Cornea, Conjunctiva and Tear Film

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Publisher : Elsevier Health Sciences
ISBN 13 : 1455728764
Total Pages : 474 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Ocular Surface Disease: Cornea, Conjunctiva and Tear Film by : Edward J Holland

Download or read book Ocular Surface Disease: Cornea, Conjunctiva and Tear Film written by Edward J Holland and published by Elsevier Health Sciences. This book was released on 2013-05-17 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ocular Surface Disease: Cornea, Conjunctiva and Tear Film incorporates current research and the latest management strategies as well as classification systems and treatment paradigms for all forms of ocular surface disease. This is the first comprehensive resource that helps you to meet ocular surface disease challenges effectively using today's best medical and surgical approaches. Get the complete, evidence-based guidance you need to provide optimal care for your patients with ocular surface disease. Implement the latest drug treatments and surgical interventions to provide better outcomes with fewer complications. Hone and expand your surgical skills by watching videos of leading experts performing advanced procedures including ocular surface transplantation techniques; amniotic membrane transplantation; pterygium surgery; lamellar keratoplasty (DALK) in ocular surface disease; and keratoprosthesis surgery. Visualize how to proceed by reviewing detailed, full-color images and consulting new classification systems and treatment paradigms for mild to severe forms of ocular surface disease. Take it with you anywhere! Access the full text, downloadable image library, video clips, and more online at expertconsult.com.

Chemical, Microbiological, Health and Comfort Aspects of Indoor Air Quality - State of the Art in SBS

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Publisher : Springer Science & Business Media
ISBN 13 : 940158088X
Total Pages : 378 pages
Book Rating : 4.4/5 (15 download)

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Book Synopsis Chemical, Microbiological, Health and Comfort Aspects of Indoor Air Quality - State of the Art in SBS by : Helmut Knöppel

Download or read book Chemical, Microbiological, Health and Comfort Aspects of Indoor Air Quality - State of the Art in SBS written by Helmut Knöppel and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in indoor air quality (IAQ) is growing at public, political and scientific levels. Complaints about poor IAQ, associated with acute symptoms such as mucous irritation, headaches and bad odor occur frequently, particularly in the office environment, where typical patterns of symptoms often occur, leading to the coining of the term `Sick Building Syndrome'. In the present book, internationally known experts address the following issues: the dynamics of the indoor environment and strategies for indoor measurement chemical and microbiological pollution, important species, sources and detection methods effects of indoor pollution, in particular sensory irritation, including odor airway, eye and skin irritation by organic indoor pollutants and their assessment immune effects, including allergic sensitization chemical hyper-responsiveness controlled human reactions to organic pollutants building investigation: approaches and results source characterization and control criteria, norms and techniques in indoor air pollution, and regulatory aspects. The complex, multifactorial nature of sick building syndrome requires multidisciplinary collaboration from very diverse fields. It is evident that communication between researchers coming from very different areas, all speaking their own language, is a difficult task. This book, presenting as it does the state of the art on sick buildings and how to cure them, is a sound foundation on which to build for the future.

Handbook of Nutrition, Diet, and the Eye

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Publisher : Academic Press
ISBN 13 : 012815246X
Total Pages : 668 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Handbook of Nutrition, Diet, and the Eye by : Victor R. Preedy

Download or read book Handbook of Nutrition, Diet, and the Eye written by Victor R. Preedy and published by Academic Press. This book was released on 2019-06-11 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Nutrition, Diet, and the Eye, Second Edition, thoroughly addresses common features and etiological factors on how dietary and nutritional factors affect the eye. The ocular system is perhaps one of the least studied organs in diet and nutrition, yet the consequences of vision loss are devastating. There are a range of ocular defects that have either their origin in nutritional deficiencies/excess or have been shown to respond favorably to nutritional components. Featuring a new section on animal model studies where both the ocular problem and dietary remedies can be varied, there are also new chapters on dietary supplements. Serves as a foundational collection for neuroscience, neurology and nutrition researchers, illustrating the importance of nutrition and diet in eye health and function Provides a common language for readers to discuss how nutritional factors and related diseases and syndromes affect the eye Features new chapters on infectious diseases of the eye where nutrition is a factor Discusses animal model studies, dietary supplements, natural dietary extracts from around the world, and age-related changes in ocular health

Dry Eye Disease

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Publisher : Thieme
ISBN 13 : 163853232X
Total Pages : 234 pages
Book Rating : 4.6/5 (385 download)

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Book Synopsis Dry Eye Disease by : Penny A. Asbell

Download or read book Dry Eye Disease written by Penny A. Asbell and published by Thieme. This book was released on 2011-01-01 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Techniques from the experts for managing the most common problem in eye patients Here is the ultimate guide to managing the most frequently encountered problem in the eye patient--dry eye disease. Dry Eye Disease: The Clinician's Guide to Management provides the latest diagnostic techniques, new approaches for classifying patients, and state-of-the-art, evidence-based medical and surgical treatments. The book opens with a review of the epidemiology and the multifactorial etiologies of dry eye disease. The authors guide the reader through taking a thorough patient history, conducting the diagnostic examination, and using clinical tests to make a confident evaluation of the severity of the disease. In their discussion of both medical and surgical techniques for management, the authors describe common treatments, such as punctal plugs, lid treatment, artificial tears, as well as innovative treatments including autologous serum drops, stem cell transplantation, and more. Highlights: Contributions from such internationally known experts as Shigeru Kinoshita, M. Reza Dana, Maurizio Rolando, Kazuo Tsubota, Kelly Nichols, Janine Smith, J. Daniel Nelson, Jay S. Pepose, Mark J. Mannis, Friedrich E. Kruse, Teruo Nishida, and others Thorough discussion of new and emerging diagnostic tests, including tear osmolarity, impression cytology, corneal permeability, and visual function, enables readers to expand and sharpen their techniques A bullet-point list of key points at the beginning of each chapter is ideal for rapidly reviewing important concepts Numerous tables organize the results of clinical surveys of common symptoms and factors associated with dry eye disease An extensive list of references, as well as a chapter covering online resources, helps the reader keep abreast of the newest research This is a timely reference for all ophthalmologists, optometrists, and trainees in these specialties. It is essential reading for practitioners treating contact lens wearers and refractive surgery patients, as well as patients with glaucoma and age-related macular degeneration.

Feedback Systems

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Publisher : Princeton University Press
ISBN 13 : 069121347X
Total Pages : pages
Book Rating : 4.6/5 (912 download)

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Book Synopsis Feedback Systems by : Karl Johan Åström

Download or read book Feedback Systems written by Karl Johan Åström and published by Princeton University Press. This book was released on 2021-02-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential introduction to the principles and applications of feedback systems—now fully revised and expanded This textbook covers the mathematics needed to model, analyze, and design feedback systems. Now more user-friendly than ever, this revised and expanded edition of Feedback Systems is a one-volume resource for students and researchers in mathematics and engineering. It has applications across a range of disciplines that utilize feedback in physical, biological, information, and economic systems. Karl Åström and Richard Murray use techniques from physics, computer science, and operations research to introduce control-oriented modeling. They begin with state space tools for analysis and design, including stability of solutions, Lyapunov functions, reachability, state feedback observability, and estimators. The matrix exponential plays a central role in the analysis of linear control systems, allowing a concise development of many of the key concepts for this class of models. Åström and Murray then develop and explain tools in the frequency domain, including transfer functions, Nyquist analysis, PID control, frequency domain design, and robustness. Features a new chapter on design principles and tools, illustrating the types of problems that can be solved using feedback Includes a new chapter on fundamental limits and new material on the Routh-Hurwitz criterion and root locus plots Provides exercises at the end of every chapter Comes with an electronic solutions manual An ideal textbook for undergraduate and graduate students Indispensable for researchers seeking a self-contained resource on control theory

Contact Lens Complications

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Publisher :
ISBN 13 :
Total Pages : 292 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Contact Lens Complications by : Nathan Efron

Download or read book Contact Lens Complications written by Nathan Efron and published by . This book was released on 2004 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new 2nd edition of this practical manual has been completely updated and revised to reflect the most current knowledge, research findings, technological developments, and updates in contact lens materials. With its broad coverage and systematic approach, it provides an intuitive approach to understanding, diagnosing, and treating contact lens complications. This lavishly illustrated text is recognized as a definitive resource on contact lens for practitioners and students.

Research Awards Index

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Publisher :
ISBN 13 :
Total Pages : 1128 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on with total page 1128 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comprehensive Human Physiology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642609465
Total Pages : 2478 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Comprehensive Human Physiology by : Rainer Greger

Download or read book Comprehensive Human Physiology written by Rainer Greger and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 2478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Human Physiology is a significantly important publication on physiology, presenting state-of-the-art knowledge about both the molecular mechanisms and the integrative regulation of body functions. This is the first time that such a broad range of perspectives on physiology have been combined to provide a unified overview of the field. This groundbreaking two-volume set reveals human physiology to be a highly dynamic science rooted in the ever-continuing process of learning more about life. Each chapter contains a wealth of original data, clear illustrations, and extensive references, making this a valuable and easy-to-use reference. This is the quintessential reference work in the fields of physiology and pathophysiology, essential reading for researchers, lecturers and advanced students.

Ophthalmology and the Ageing Society

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Publisher : Springer Science & Business Media
ISBN 13 : 3642363245
Total Pages : 229 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Ophthalmology and the Ageing Society by : Hendrik P.N. Scholl

Download or read book Ophthalmology and the Ageing Society written by Hendrik P.N. Scholl and published by Springer Science & Business Media. This book was released on 2013-05-29 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ageing of the world’s population is one of the major achievements of modern society. By 2050, an estimated 2 billion people will be aged 60 years or over. However, ageing poses major challenges and this is especially true for the field of ophthalmology, given that the major eye diseases – age-related macular degeneration, glaucoma, and cataract – predominantly affect the elderly. The challenges facing ophthalmology in an ageing society have not previously been addressed in a comprehensive way, although there are common denominators of the various eye diseases that affect the elderly. This book provides such a comprehensive overview encompassing epidemiology, risk factors, current treatment and prophylaxis, disability, co-morbidity, and the impact on quality of life. World leaders in their respective fields provide state-of-the-art knowledge on the geriatric aspects of ophthalmology that will help to improve the management of this growing patient population.

Cornea E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 032335758X
Total Pages : 2189 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Cornea E-Book by : Mark J Mannis

Download or read book Cornea E-Book written by Mark J Mannis and published by Elsevier Health Sciences. This book was released on 2016-09-23 with total page 2189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly praised in its first three editions, Cornea has become a market-leading cornerstone text and the immediate go-to resource for anyone working in this hugely popular and evolving sub-specialty. Offered over two volumes and featuring the knowledge of over 200 experts worldwide, it presents state-of-the-art coverage of the expanding range of contemporary corneal surgery, new diagnostic technology, and medical management of corneal and external disease as well as ocular surface disease. This updated edition includes 20 brand-new chapters, while an enhanced focus on images provides key visual guidance in this challenging field. Exceptionally clear illustrations, diagnostic images, and step-by-step surgical photographs offer superb visual guidance. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos, and references from the book on a variety of devices. 20 brand-new chapters cover the latest advances in the field, such as DMEK, Ultra-Thin DSEK and DSAEK techniques; endothelial cell transplantation; keratoplasty and prosthokeratoplasty techniques; collagen cross-linking; and new refractive surgical techniques (presbyopic implants and SMILE surgery). 60 video clips on Expert Consult show new footage of the latest corneal surgery techniques, including Boston Keratoprosthesis, corneal inlay surgery, and lenticule extraction. Boasts over 170 chapters with unique, cutting-edge content, as well as 2,300 clear illustrations – 670 of which are new to this edition. Presents a detailed exposition of the growing number of techniques for lamellar keratoplasty, including outcomes. Includes new sections on the latest developments in the management of ocular surface disease. Key point overviews in each chapter offer easier access to crucial information.

The Sense of an Ending

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Publisher : Vintage
ISBN 13 : 0307957330
Total Pages : 158 pages
Book Rating : 4.3/5 (79 download)

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Book Synopsis The Sense of an Ending by : Julian Barnes

Download or read book The Sense of an Ending written by Julian Barnes and published by Vintage. This book was released on 2011-10-05 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: BOOKER PRIZE WINNER • NATIONAL BESTSELLER • A novel that follows a middle-aged man as he contends with a past he never much thought about—until his closest childhood friends return with a vengeance: one of them from the grave, another maddeningly present. A novel so compelling that it begs to be read in a single setting, The Sense of an Ending has the psychological and emotional depth and sophistication of Henry James at his best, and is a stunning achievement in Julian Barnes's oeuvre. Tony Webster thought he left his past behind as he built a life for himself, and his career has provided him with a secure retirement and an amicable relationship with his ex-wife and daughter, who now has a family of her own. But when he is presented with a mysterious legacy, he is forced to revise his estimation of his own nature and place in the world.

Anatomy and Physiology

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Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: