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Characterization Of Ngfi A And The Dendritic Immediate Early Gene Arc In The Hippocampus Of Rapidly Kindled Rats
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Book Synopsis Characterization of NGFI-A and the Dendritic Immediate-early Gene Arc in the Hippocampus of Rapidly Kindled Rats by : Marsha Rae Penner
Download or read book Characterization of NGFI-A and the Dendritic Immediate-early Gene Arc in the Hippocampus of Rapidly Kindled Rats written by Marsha Rae Penner and published by . This book was released on 2001 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal plasticity in the adult central nervous system is essential for dealing with environmental stimuli and injury-related changes. Kindling refers to the process whereby repeated, electrical stimulations of the brain leads to long-lasting or permanent changes in brain function. Kindling is typically established over several weeks using once daily stimulation, so called traditional kindling. It has been hypothesized that kindling may also be established within hours using different stimulation parameters, so called rapid kindling. However, studies investigating this possibility have provided conflicting results. In addition, while there has been intensive investigation into the mechanisms that mediate the pathological plasticity associated with kindling, much still remains to be elucidated. The expression of immediate-early genes (IEGs) is considered the first genomic response to underlie plastic changes in the CNS. Nerve growth factor induced gene-A (NGFI-A) and activity regulated cytoskeletal protein (ARC) are IEGs whose expression has been implicated in the transition from short-term to long-term synaptic plasticity. Based on these findings, the ability of rapid kindling to establish a kindled state and the response profiles of NGFI-A and ARC associated with rapid kindling were assessed.
Author :Marsha R. (Marsha Rae) Penner Publisher :National Library of Canada = Bibliothèque nationale du Canada ISBN 13 :9780612664555 Total Pages :220 pages Book Rating :4.6/5 (645 download)
Book Synopsis Characterization of NGFI-A and the Dendritic Immediate-early Gene ARC in the Hippocampus of Rapidly Kindled Rats [microform] by : Marsha R. (Marsha Rae) Penner
Download or read book Characterization of NGFI-A and the Dendritic Immediate-early Gene ARC in the Hippocampus of Rapidly Kindled Rats [microform] written by Marsha R. (Marsha Rae) Penner and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 2001 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Plasticity in the Visual System by : Raphael Pinaud
Download or read book Plasticity in the Visual System written by Raphael Pinaud and published by Springer Science & Business Media. This book was released on 2006-04-04 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of neural plasticity enable the encoding and memorization of information based on sensory inputs and can be harnessed to partially restore function after CNS assault such as stroke or head trauma. In the present book, experts from the field of visual system plasticity describe and evaluate the evidence for neural mechanisms proposed to underlie CNS plasticity in the major divisions of the brain dedicated to visual processing, the retina, sub-cortical structures and cortex. We present studies from a wide variety of disciplines that range from molecular biology to neurophysiology and computer modeling. Leading investigators discuss their own work, and integrate this research with colleagues from other specializations. The book points out future applications for this research including clinical uses and engineering within the biomedical sciences. This book is an exciting and thought provoking read for all levels of science enthusiast interested in the physical basis of learning and cognition.
Book Synopsis Brain Repair After Stroke by : Steven C. Cramer
Download or read book Brain Repair After Stroke written by Steven C. Cramer and published by Cambridge University Press. This book was released on 2010-10-28 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.
Book Synopsis The Hippocampus Book by : Per Andersen
Download or read book The Hippocampus Book written by Per Andersen and published by Oxford University Press. This book was released on 2007 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.
Download or read book Cortical Plasticity written by Sam Fazeli and published by Garland Science. This book was released on 2020-08-18 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an insight into the rapidly growing field of cortical plasticity. It brings together diverse experimental approaches to the study of activity-dependent changes in neuronal connections, as exemplified by long-term potentiation (LTP) and long-term depression (LTD).
Download or read book EJB Reviews written by P. Christen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the mid-1980s the European Journal of Biochemistry set out to publish review articles. The enterprise proved successful, resulting in high-level reviews written by well-known scientists appearing in the Journal. The reviews represent emerging and rapidly growing fields of research in fundamental as well as applied areas of biochemistry, such as medicine, biotechnology, agriculture and nutrition. Novel methodological and technological approaches which stimulate biochemical research are also included. The authors of the reviews are explicitly asked to be critical, selective, evaluative and interdisciplinary oriented. The reviews should encourage young scientists to think independently and creatively, and inform active investigators about the state of the art in a given field.
Book Synopsis Society for Neuroscience Abstracts by : Society for Neuroscience. Annual Meeting
Download or read book Society for Neuroscience Abstracts written by Society for Neuroscience. Annual Meeting and published by . This book was released on 1993 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Transcription Factors in the Nervous System by : Gerald Thiel
Download or read book Transcription Factors in the Nervous System written by Gerald Thiel and published by John Wiley & Sons. This book was released on 2006-05-12 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first book to cover neural development, neuronal survival and function on the genetic level outlines promising approaches for novel therapeutic strategies in fighting neurodegenerative disorders, such as Alzheimer's disease. Focusing on transcription factors, the text is clearly divided into three sections devoted to transcriptional control of neural development, brain function and transcriptional dysregulation induced neurological diseases. With a chapter written by Nobel laureate Eric Kandel, this is essential reading for neurobiologists, geneticists, biochemists, cell biologists, neurochemists and molecular biologists.
Book Synopsis The Cognitive Neurosciences by : Michael S. Gazzaniga
Download or read book The Cognitive Neurosciences written by Michael S. Gazzaniga and published by MIT Press. This book was released on 2009-09-18 with total page 1377 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The fourth edition of The Cognitive Neurosciences continues to chart new directions in the study of the biologic underpinnings of complex cognition - the relationship between the structural and physiological mechanisms of the nervous system and the psychological reality of the mind. The material in this edition is entirely new, with all chapters written specifically for it." --Book Jacket.
Download or read book Galanin written by Tomas Hökfelt and published by Springer Science & Business Media. This book was released on 2010-08-18 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Galanin is a neuropeptide found both in the central and peripheral nervous system. The 29-amino acid peptide (named after its N-terminal glycine and C-terminal alanine) was identified in 1983 by its C-terminal amidation. This 'reverse' approach, that is to discover a substance through a distinct chemical feature, and only subsequently to characterize its biological activity, was novel and has been successful in the identification of several other peptides. After the structure of galanin was determined in 1983, functional studies were performed with material purified from natural sources until the synthetic form of the peptide became available. Galanin can act as transmitter, modulator and trophic factor, and is involved in a number of physiological processes such as hormone secretion, cardiovascular mechanisms, feeding and cognition. This peptide may also be of significance for a number of pathological processes/disorders including pain, depression, Alzheimer's disease, epilepsy, addiction and cancer. This wide diversity of actions is mediated by three galanin receptor subtypes. The studies reviewed in this volume give a fairly complete overview of the spectrum of the biological actions and functions of galanin and its receptors and on possible therapeutic applications in a number of pathological conditions.
Book Synopsis The Neuroscience of Cocaine by : Victor R Preedy
Download or read book The Neuroscience of Cocaine written by Victor R Preedy and published by Academic Press. This book was released on 2017-05-23 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neuroscience of Cocaine: Mechanisms and Treatment explores the complex effects of this drug, addressing the neurobiology behind cocaine use and the psychosocial and behavioral factors that impact cocaine use and abuse. This book provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms. Cocaine is one of the most highly abused illicit drugs worldwide and is frequently associated with other forms of drug addiction and misuse, but researchers are still struggling to understand cocaine’s neuropharmacological profile and the mechanisms of its effects and manifestations at the cognitive level. Cessation of cocaine use can lead to numerous adverse withdrawal conditions, from the cellular and molecular level to the behavioral level of the individual user. Written by worldwide experts in cocaine addiction, this book assists neuroscientists and other addiction researchers in unraveling the many complex facets of cocaine use and abuse. Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Illustrated in full color Provides unique full coverage of all aspects of cocaine and its related pathology Provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms
Book Synopsis Neurochemical Aspects of Excitotoxicity by : Akhlaq A. Farooqui
Download or read book Neurochemical Aspects of Excitotoxicity written by Akhlaq A. Farooqui and published by Springer Science & Business Media. This book was released on 2007-11-20 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading researchers offer cutting-edge information on glutamate metabolism in the brain, examining the role of glutamate transporters and the involvement of glutamate receptors in the pathogenesis of acute neural trauma and neurodegenerative diseases. In addition, the authors discuss the treatment of these diseases with endogenous and exogenous antioxidants and glutamate receptor antagonists.
Book Synopsis Neurobiology of the Locus Coeruleus by :
Download or read book Neurobiology of the Locus Coeruleus written by and published by Elsevier. This book was released on 1991-11-21 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of the Locus Coeruleus
Download or read book Molecular Basis of Memory written by and published by Academic Press. This book was released on 2014-01-30 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special volume of Progress in Molecular Biology and Translational Science provides a current overview of how memory is processed in the brain. A broad range of topics are presented by leaders in the field, ranging from brain circuitry to synaptic plasticity to the molecular machinery that contributes to the brain's ability to maintain information across time. Memory systems in the prefrontal cortex, hippocampus and amygdala are considered as well. In addition, the volume covers recent contributions to our understanding of memory from in vivo imaging, optogenetic, electrophysiological, biochemical and molecular biological studies. Articles from world renowned experts in memory Covering topics from signaling, epigenetic, RNA translation to plasticity Methodological approaches include molecular and cellular, behavioral, electrophysiological, optogenetic and functional imaging
Book Synopsis Kindling and Synaptic Plasticity by : MORRELL
Download or read book Kindling and Synaptic Plasticity written by MORRELL and published by Birkhäuser. This book was released on 1991 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kindling and long-term potentiation, among the most active fields of research in neuroscience today, serve as fundamental experimental models of use-dependent synaptic plasticity in the mammalian brain. The recognition of kindling in the late 1960s and its relevance both to epilepsy and to the basis
Book Synopsis Blood-Spinal Cord and Brain Barriers in Health and Disease by : Hari Shanker Sharma
Download or read book Blood-Spinal Cord and Brain Barriers in Health and Disease written by Hari Shanker Sharma and published by Elsevier. This book was released on 2003-12-21 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent research into the anatomy and pathophysiology of the blood-brain and blood-spinal cord barriers suggests that a breakdown in these barriers can result in several diseases affecting the central nervous system (CNS). This book presents new findings in the area of blood-brain barrier research that suggest barriers play important roles in health and disease conditions. It also discusses the development of new drugs that can modulate the barrier function in the CNS and may provide new approaches to treating neurological diseases such as Alzheimer's disease and other motor neuron diseases, as well as spinal cord trauma. Key Features * Presents the recent progress made in the research on the blood-brain and spinal cord barrier * Contains numerous illustrations of light and electron micrographs * Includes Foreword written by two eminent researchers in the field, Milton Brightman and Jorge Cervos-Navarro
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