Characterization Of Nanomaterial Interactions At The Biological Interfaces

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Characterization of Nanomaterial Interactions at the Biological Interfaces

Author : Kyoungtea Kim
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (134 download)

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Book Synopsis Characterization of Nanomaterial Interactions at the Biological Interfaces by : Kyoungtea Kim

Download or read book Characterization of Nanomaterial Interactions at the Biological Interfaces written by Kyoungtea Kim and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in nanomaterials has arisen from their unique physiochemical properties with applications in medicine, industrial processing, consumer goods, and agriculture due to their unique physicochemical properties and applications. With the increase in industrial scale nanomaterial synthesis and application, living cells are increasingly likely to be exposed to nanomaterials in the environment. Given that the cell membrane/wall is the initial point of contact for living cells with foreign materials, understanding nanomaterial interactions with extracellular surfaces at the molecular level is required to assess and predict the potential deleterious impacts of nanomaterials on living cells/organisms. In terms of abundance, proteins in biological fluids or serums are highly likely to interact with nanomaterials. Protein association with nanomaterials is known to accompany subsequent protein conformational changes. Considering protein conformation is finely regulated in living cells, altered protein conformations induced by interactions with nanomaterials need to be investigated to better understand potential adverse impacts on living organisms. The overarching goal of the studies presented here is to construct model biological systems and elucidate their interaction with nanomaterials. We here developed model biological interfaces, investigated their molecular level interactions with nanomaterial, and demonstrated that some of our model biological interfaces are representative of actual biological interfaces. We also summarized nanomaterial interactions with proteins and subsequent protein conformational changes. The characterization of the nano-bio interactions, at the molecular level, would contribute to establishing nanomaterial design rules to improve their properties for applications and ultimately supports the implementation of sustainable nanotechnology.

Protein-Nanoparticle Interactions

Author : Masoud Rahman
Publisher : Springer Science & Business Media
ISBN 13 : 3642375553
Total Pages : 95 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Protein-Nanoparticle Interactions by : Masoud Rahman

Download or read book Protein-Nanoparticle Interactions written by Masoud Rahman and published by Springer Science & Business Media. This book was released on 2013-06-24 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a “biological identity” to their surfaces (referred to as a “corona”), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called “bio-nano interface,” has been very rarely studied in detail to date, though the interest in this topic is rapidly growing. In this book, the importance of the physiochemical characteristics of nanoparticles for the properties of the protein corona is discussed in detail, followed by comprehensive descriptions of the methods for assessing the protein-nanoparticle interactions. The advantages and limitations of available corona evaluation methods (e.g. spectroscopy methods, mass spectrometry, nuclear magnetic resonance, electron microscopy, X-ray crystallography, and differential centrifugal sedimentation) are examined in detail, followed by a discussion of the possibilities for enhancing the current methods and a call for new techniques. Moreover, the advantages and disadvantages of protein-nanoparticle interaction phenomena are explored and discussed, with a focus on the biological impacts.

Microbial Interactions at Nanobiotechnology Interfaces

Author : R. Navanietha Krishnaraj
Publisher : John Wiley & Sons
ISBN 13 : 1119617170
Total Pages : 416 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Microbial Interactions at Nanobiotechnology Interfaces by : R. Navanietha Krishnaraj

Download or read book Microbial Interactions at Nanobiotechnology Interfaces written by R. Navanietha Krishnaraj and published by John Wiley & Sons. This book was released on 2021-10-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: MICROBIAL INTERACTIONS AT NANOBIOTECHNOLOGY INTERFACES This book covers a wide range of topics including synthesis of nanomaterials with specific size, shape, and properties, structure-function relationships, tailoring the surface of nanomaterials for improving the properties, interaction of nanomaterials with proteins/microorganism/eukaryotic cells, and applications in different sectors. This book also provides a strong foundation for researchers who are interested to venture into developing functionalized nanomaterials for any biological applications in their research. Practical concepts such as modelling nanomaterials, and simulating the molecular interactions with biomolecules, transcriptomic or genomic approaches, advanced imaging techniques to investigate the functionalization of nanomaterials/interaction of nanomaterials with biomolecules and microorganisms are some of the chapters that offer significant benefits to the researchers.

Nanomaterial Interfaces in Biology

Author : Paolo Bergese
Publisher : Humana
ISBN 13 : 9781493960071
Total Pages : 0 pages
Book Rating : 4.9/5 (6 download)

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Book Synopsis Nanomaterial Interfaces in Biology by : Paolo Bergese

Download or read book Nanomaterial Interfaces in Biology written by Paolo Bergese and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The intersection of nanotechnology with biology has given rise to numerous ideas for new ways to use nanotechnology for biological applications. Nanomaterials possess unique size- and material-dependent properties which make them attractive for improving regular biomedical fields, such as drug delivery, imaging, therapy, and diagnostics. Divided into three convenient sections, Nanomaterial Interfaces in Biology: Methods and Protocols covers protocols describing synthesis, fabrication, and construction of bio-nanomaterial interfaces, characterization protocols of bio-nanomaterial interfaces, and applications which utilize the bio-nanomaterial interfaces. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible Nanomaterial Interfaces in Biology: Methods and Protocols will serve the new and emerging scientific community, enabling new capabilities and technologies that were not previously possible in medicine and biology.

Analytical Models to Understand Interactions at the Nano-bio Interface

Author : Christian A. Reardon-Lochbaum
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (134 download)

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Book Synopsis Analytical Models to Understand Interactions at the Nano-bio Interface by : Christian A. Reardon-Lochbaum

Download or read book Analytical Models to Understand Interactions at the Nano-bio Interface written by Christian A. Reardon-Lochbaum and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials are synthesized for use in a wide variety of consumer and industrial products, which will inadvertently lead to nanomaterial exposure to biological systems; additionally, nanomaterials are being explored for application in both the medical and agricultural fields, which constitutes intentional nanomaterial exposure to biological systems. With the rapid expansion in the quantity and variety of nanomaterials being synthesized, it has become a huge undertaking to characterize the interactions at the nano-bio interface. Here, I present a series of studies that work towards developing and utilizing model systems to characterize interactions between nanomaterials and cellular membranes or biological fluids. This work targets two model membrane systems-the supported lipid bilayer and unilamellar vesicles-and one biological fluid model system-plant xylem fluid. Membranes make up one of the cells most robust defense systems from invasive material. They provide both a physical and chemical barrier between the interior and exterior of the cell. Cellular membranes are complex, containing multitudes of different lipid varieties that assemble into surface features and incorporate membrane proteins that actively perform tasks while contained within the bilayer. Due to this complexity, interactions between native cell membranes and nanoparticles are difficult to characterize when performing whole cell exposure studies. Lipid bilayer model systems simplify the cell membrane down to a handful of molecular components so that fundamental mechanisms of interaction between nanoparticles and lipids can be studied. The work presented here has focused on the simplest variety of model lipid bilayer, the single component lipid bilayer, to allow for rigorous characterization of molecular interactions with nanomaterials. We used the first model system highlighted here, supported lipid bilayers, to understand the interactions between ligand coated gold nanoparticles and cellular membranes. We exposed supported lipid bilayers to 2 nm gold nanoparticles functionalized with ligands of systematically increasing lipophilicity. We found that increasing lipophilicity of ligands increased the maximum mass density of nanoparticle adsorption and the rate at which nanoparticles converted to the quasi-irreversibly adsorbed state. The quasi-irreversibly bound state was linked to ligand insertion, which we define by the ability of a ligand to form hydrophobic contact with lipid tail groups. An issue with previous applications of the supported lipid bilayer system is that it under predicts the interaction of anionic nanoparticles with the membrane when compared to both computational and cellular exposure models. We found that interactions between anionic nanoparticles and supported lipid bilayers are impacted by the composition of the substrate upon which the bilayer is built. Specifically, we find that SiO2-a widely used substrate-hindered the adsorption of anionic gold nanoparticles to the bilayer as compared to a Au substrate. This change is attributed to both the increased attractive van der Waals forces and decreased repulsive Coulombic forces of nanoparticles interacting with bilayers formed on Au vs SiO2 substrates, respectively. A second model membrane system, unilamellar vesicles, has been used to monitor nanomaterial induced disruption or remodeling of lipid bilayers; however, a difficulty when using this model system is the inability to rigorously track the nanomaterial with respect to a disruption or remodeling event, due to the small size dimensions of the nanoparticle. We work to develop a method of tracking both fluorescent vesicles and nanomaterials simultaneously with convex lens induced confinement. The final set of studies presented here utilizes a third model biological system: plant xylem fluid. Nanomaterial based approaches to suppressing plant disease and increasing crop yields are being explored; however, little is known about molecular level interactions between the nanomaterials proposed in this research and the plants. We conducted a set of measurements to understand how copper oxide nanoparticles, a nanomaterial that has shown promise as a micronutrient delivery to plants, interact with the biomolecules found in xylem fluid. We found that proteins from the xylem fluid associate with the nanoparticles, a phenomenon known as biomolecular corona formation. Additionally, we found that protein adsorption is selective to a subset of proteins found within the xylem fluid and the corona evolves over time.0́3

Spectroscopic Studies of Silica Nanoparticles

Author : Sean E. Lehman
Publisher :
ISBN 13 :
Total Pages : 168 pages
Book Rating : 4.:/5 (13 download)

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Book Synopsis Spectroscopic Studies of Silica Nanoparticles by : Sean E. Lehman

Download or read book Spectroscopic Studies of Silica Nanoparticles written by Sean E. Lehman and published by . This book was released on 2016 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primarily concerned with manipulation and study of matter at the nanoscale, the concept of nanoscience encompasses ideas such as nanomaterial synthesis, characterization, and applications to modern scientific and societal problems. These problems encompass a broad range of issues such as energy storage and conversion, medical diagnostics and treatment, environmental remediation and detection, carbon economy and as well as many others. Silica nanoparticles of porous morphology have broad application to many of these issues. In particular, the utility of silica nanoparticles is facilitated by their large intrinsic surface area, tunable surface chemistry, and synthetic variability in both their size and morphology. This facilitates applications to these problems. However, extensive characterization and deeper understanding is needed before full implementation in key applications can be realized. The work described in this thesis aims to explore fundamental and applied characterization of silica nanoparticles that might be used in biomedical and environmental applications. Fundamental studies of functionalized nanomaterials using NMR spectroscopy reveal complex, dynamic phenomena related to--and ultimately deriving from--the intrinsic and/or modified surface chemistry. Applied studies of nanomaterial-biological interfaces demonstrate free radical chemistry as dominating the toxic response of the materials when exposed to biological systems of interest. Characterization of protein adsorbed on the interface reinforces the ubiquitous nature of protein adsorption on nanomaterial surface in biological and environmental media. Overall, this work illuminates and highlights complex changes that take place in aqueous solution for silica nanoparticles of varied morphology and surface chemistry.

Biointeractions of Nanomaterials

Author : Vijaykumar B. Sutariya
Publisher : CRC Press
ISBN 13 : 1466582383
Total Pages : 484 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Biointeractions of Nanomaterials by : Vijaykumar B. Sutariya

Download or read book Biointeractions of Nanomaterials written by Vijaykumar B. Sutariya and published by CRC Press. This book was released on 2014-07-29 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: An examination of the widespread application of nano materials in biology, medicine, and pharmaceuticals and the accompanying safety concerns, Bio-interactions of Nano Materials addresses the issues related to toxicity and safety of nano materials and nano systems. It covers the interactions in biological systems and presents various tools and methods used to evaluate the nano toxicity and nano safety issues. Written by leading scientists, the book focuses on the bio-interaction of nano materials, covering various techniques and tests which have been developed to evaluate the toxicity of materials at the nano level. The book highlights the challenges of bio-interactions of nano materials and possible solutions to those challenges. It addresses the assessment and characterization of nano systems in bio-environments, toxicity and bio-sensing devices for toxicity assessment, carbon nano tubes and pulmonary toxicity, and nano toxicity of solid lipid nanoparticles. It also discusses nano safety concerns and solutions, including the effects of nano particles on different organs and regulatory implications of nano materials. These particles may be used to encapsulate drugs, recognize biological markers, or visualize body tissues among many other possibilities, all enabling their widespread application in biology, medicine, and pharmaceutics. Indeed, these nano materials may have beneficial effects that have not even been imagined. This book gives you an understanding of the safety issues, how to assess for them, and how to mitigate them to move forward in research and development of new applications for nano materials.

Nanomaterial Characterization

Author : Ratna Tantra
Publisher : John Wiley & Sons
ISBN 13 : 1118753933
Total Pages : 320 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Nanomaterial Characterization by : Ratna Tantra

Download or read book Nanomaterial Characterization written by Ratna Tantra and published by John Wiley & Sons. This book was released on 2016-03-24 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterial Characterization Providing various properties of nanomaterials and the various methods available for their characterization Over the course of the last few decades, research activity on nanomaterials has gained considerable press coverage. The use of nanomaterials has meant that consumer products can be made lighter, stronger, esthetically more pleasing, and less expensive. The significant role of nanomaterials in improving the quality of life is clear, resulting in faster computers, cleaner energy production, target-driven pharmaceuticals, and better construction materials. It is not surprising, therefore, that nanomaterial research has really taken off, spanning across different scientific disciplines from material science to nanotoxicology. A critical part of any nanomaterial research, however, is the need to characterize physicochemical properties of the nanomaterials, which is not a trivial matter. Nanomaterial Characterization: An Introduction is dedicated to understanding the key physicochemical properties and their characterization methods. Each chapter begins by giving an overview of the topic before a case study is presented. The purpose of the case study is to demonstrate how the reader may make use of the background information presented to them and show how this can be translated to solve a nanospecific application scenario. Thus, it will be useful for researchers in helping them design experimental investigations. The book begins with a general overview of the subject, thus giving the reader a solid foundation to nanomaterial characterization. Nanomaterial Characterization: An Introduction features: Nanomaterial synthesis and reference nananomaterials Key physicochemical properties and their measurements including particle size distribution by number, solubility, surface area, surface chemistry, mechanical/tribological properties, and dustiness Scanning tunneling microscopy methods operated under extreme conditions Novel strategy for biological characterization of nanomaterial methods Methods to handle and visualize multidimensional nanomaterial characterization data The book is written in such a way that both students and experts in other fields of science will find the information useful, whether they are in academia, industry, or regulation, or those whose analytical background may be limited.There is also an extensive list of references associated with every chapter to encourage further reading.

Measuring Biological Impacts of Nanomaterials

Author : Joachim Wegener
Publisher : Springer
ISBN 13 : 3319248235
Total Pages : 221 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Measuring Biological Impacts of Nanomaterials by : Joachim Wegener

Download or read book Measuring Biological Impacts of Nanomaterials written by Joachim Wegener and published by Springer. This book was released on 2016-02-02 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews several aspects of the biological response to nanoscale particles on a molecular and cellular level. Nanoscale materials and nanoscale particles in particular have interesting properties and beneficial applications. While they thus have entered our daily lifes on many different levels (from electronics, over textiles, packaging or surface modifications, to biomedical applications), general rules describing their interaction with biological structures and biological matter are still difficult to derive. The existing literature suggests a variety of interaction schemes between nanoparticles and biological objects, not dispelling the public concerns about possible health effects and harmful properties. A systematic approach to the problem is needed and timely. This book specifically emphasizes bioanalytical problems starting from the characterization of the nanomaterials to the pitfalls and potential artifacts of state-of-the-art cytotoxicity assays that are frequently used to study harmful effects on cells. It also highlights the application of label-free bioanalytical techniques that can potentially complement the present approaches and hence provide new perspectives on this highly discussed cutting-edge field of research and public concern.

Bio-Nano Interface

Author : Manoranjan Arakha
Publisher : Springer Nature
ISBN 13 : 9811625166
Total Pages : 355 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Bio-Nano Interface by : Manoranjan Arakha

Download or read book Bio-Nano Interface written by Manoranjan Arakha and published by Springer Nature. This book was released on 2021-11-27 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the unique interactions of nanoparticles with various biomolecules under different environmental conditions. It describes the consequences of these interactions on other biological aspects like flora and fauna of the niche, cell proliferation, etc. The book provides information about the novel and eco-friendly nanoparticle synthesis methods, such as continuous synthesis of nanoparticles using microbial cells. Additionally, the book discusses nanoparticles' potential impact in different areas of biological sciences like food, medicine, agriculture, and the environment. Due to their advanced physicochemical properties, nanoparticles have revolutionized biomedical and pharmaceutical sciences. Inside the biological milieu, nanoparticles interact with different moieties to adopt stable shape, size, and surface functionalities and form nano-biomolecular complexes. The interaction pattern at the interface form complexes determines the fate of interacting biomolecules and nanoparticles inside the biological system. Understanding the interaction pattern at the nano-bio interface is crucial for the safe use of nanoparticles in natural sciences. This book rightly addresses all questions about the interaction and the ensuing structure and function of these nano-biomolecular complexes. This book caters to students and researchers in the area of biotechnology, microbiology, and pharmaceutical sciences.

Interfaces Between Nanomaterials and Microbes

Author : Munishwar Nath Gupta
Publisher : CRC Press
ISBN 13 : 1000345017
Total Pages : 287 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Interfaces Between Nanomaterials and Microbes by : Munishwar Nath Gupta

Download or read book Interfaces Between Nanomaterials and Microbes written by Munishwar Nath Gupta and published by CRC Press. This book was released on 2021-06-23 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials are becoming ubiquitous; microbes similarly are everywhere. This book focuses on various ways the diverse nanomaterials interact with microbial communities and implications of such interactions. Both toxicity and beneficial effects of nanomaterial-microbe interactions have been covered. This includes areas such as fate and bioavailability of nanomaterials in environments, microbial synthesis of nanomaterials and antimicrobial action of nanomaterials. Fairly comprehensive but with narrow focus, the book provides useful insights into these interactions which need to be factored in while designing nanoscience based new technologies.

Characterization of Nanoparticles Intended for Drug Delivery

Author :
Publisher : Springer
ISBN 13 : 9781607619086
Total Pages : 284 pages
Book Rating : 4.6/5 (19 download)

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Book Synopsis Characterization of Nanoparticles Intended for Drug Delivery by :

Download or read book Characterization of Nanoparticles Intended for Drug Delivery written by and published by Springer. This book was released on 2011-08-14 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Characterization and Biology of Nanomaterials for Drug Delivery

Author : Shyam Mohapatra
Publisher : Elsevier
ISBN 13 : 0128140321
Total Pages : 684 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Characterization and Biology of Nanomaterials for Drug Delivery by : Shyam Mohapatra

Download or read book Characterization and Biology of Nanomaterials for Drug Delivery written by Shyam Mohapatra and published by Elsevier. This book was released on 2018-10-05 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Characterization and Biology of Nanomaterials for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery describes the techniques successfully employed for the application of nanocarriers loaded with the antioxidant enzyme, catalase, and thus targeted to endothelial cells. Methods of nanocarrier synthesis, loading within various systems, and the characterization of nanocarriers for targeting activities are covered, as are their advantages, disadvantages and applications. Reflecting the interdisciplinary nature of the subject matter, this book includes contributions by experts from different fields, all with various backgrounds and expertise. It will appeal to researchers and students from different disciplines, such as materials science, technology and various biomedical fields. Enables readers from different fields to access recent research and protocols across traditional boundaries Focuses on protocols and techniques, as well as the knowledge base of the field, thus enabling those in R&D to learn about, and successfully deploy, cutting-edge techniques Explores both current and emerging classes of nanomaterials, along with their fundamentals and applications

Bio-inorganic Hybrid Nanomaterials

Author : Eduardo Ruiz-Hitzky
Publisher : John Wiley & Sons
ISBN 13 : 3527621458
Total Pages : 521 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Bio-inorganic Hybrid Nanomaterials by : Eduardo Ruiz-Hitzky

Download or read book Bio-inorganic Hybrid Nanomaterials written by Eduardo Ruiz-Hitzky and published by John Wiley & Sons. This book was released on 2008-06-25 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: This ready reference is the first to collate the interdisciplinary knowledge from materials science, bioengineering and nanotechnology to give an in-depth overview of the topic. As such, it provides broad coverage of combinations between inorganic materials and such key biological structures as proteins, enzymes, DNA, or biopolymers. With its treatment of various application directions, including bioelectronic interfacing, tissue repair, porous membranes, sensors, nanocontainers, and DNA engineering, this is essential reading for materials engineers, medical researchers, catalytic chemists, biologists, and those working in the biotechnological and semiconductor industries.

Biological Responses to Nanoscale Particles

Author : Peter Gehr
Publisher : Springer
ISBN 13 : 3030124614
Total Pages : 344 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Biological Responses to Nanoscale Particles by : Peter Gehr

Download or read book Biological Responses to Nanoscale Particles written by Peter Gehr and published by Springer. This book was released on 2019-04-16 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book the recent progress accumulated in studies of the interaction of engineered nanoparticles with cells and cellular constituents is presented. The focus is on manufacturing and characterization of nanosized materials, their interactions with biological molecules such as proteins, the mechanisms of transport across biological membranes as well as their effects on biological functions. Fundamental molecular and cellular aspects are in the foreground of the book. A further particularity is the interdisciplinary approach, including fields such as preparatory and analytical chemistry, biophysics and the physics of colloids, advanced microscopy and spectroscopy for in-situ detection of nanoparticles, cellular toxicology and nanomedicine. Nanoscale particles are known to exhibit novel and unprecedented properties that make them different from their corresponding bulk materials. As our ability to control these properties is further advanced, a huge potential to create materials with novel properties and applications emerges. Although the technological and economic benefits of nanomaterials are indisputable, concerns have also been raised that nanoscale structuring of materials might also induce negative health effects. Unfortunately, such negative health effects cannot be deduced from the known toxicity of the corresponding macroscopic material. As a result, there is a major gap in the knowledge necessary for assessing their risk to human health.

Nano-Biomaterials For Ophthalmic Drug Delivery

Author : Yashwant Pathak
Publisher : Springer
ISBN 13 : 331929346X
Total Pages : 631 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Nano-Biomaterials For Ophthalmic Drug Delivery by : Yashwant Pathak

Download or read book Nano-Biomaterials For Ophthalmic Drug Delivery written by Yashwant Pathak and published by Springer. This book was released on 2016-11-12 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: This consolidated reference book addresses the various aspects of nano biomaterials used in ophthalmic drug delivery, including their characterization, interactions with ophthalmic system and applications in treatments of the ophthalmic diseases and disorders. In the last decade, a significant growth in polymer sciences, nanotechnology and biotechnology has resulted in the development of new nano- and bioengineered nano-bio-materials. These are extensively explored as drug delivery carriers as well as for implantable devices and scaffolds. At the interface between nanomaterials and biological systems, the organic and synthetic worlds merge into a new science concerned with the safe use of nanotechnology and nano material design for biological applications. For this field to evolve, there is a need to understand the dynamic forces and molecular components that shape these interactions. While it is impossible to describe with certainty all the bio physicochemical interactions at play at the interface, we are at a point where the pockets of assembled knowledge are providing a conceptual framework to guide this exploration, and review the impact on future product development. The book is intended as a valuable resource for academics and pharmaceutical scientists working in the field of polymers, polymers materials for drug delivery, drug delivery systems and ophthalmic drug delivery systems, in addition to medical and health care professionals in these areas.

Characterization of Nanomaterials in Complex Environmental and Biological Media

Author : Mohammed Baalousha
Publisher :
ISBN 13 :
Total Pages : 321 pages
Book Rating : 4.:/5 (126 download)

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Book Synopsis Characterization of Nanomaterials in Complex Environmental and Biological Media by : Mohammed Baalousha

Download or read book Characterization of Nanomaterials in Complex Environmental and Biological Media written by Mohammed Baalousha and published by . This book was released on 2015 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Characterization of Nanomaterials in Complex Environmental and Biological Media covers the novel properties of nanomaterials and their applications to consumer products and industrial processes. The book fills the growing gap in this challenging area, bringing together disparate strands in chemistry, physics, biology, and other relevant disciplines. It provides an overview on nanotechnology, nanomaterials, nano(eco)toxicology, and nanomaterial characterization, focusing on the characterization of a range of nanomaterial physicochemical properties of relevance to environmental and toxicolog.