Hypoxia

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306466960
Total Pages : 466 pages
Book Rating : 4.4/5 (669 download)

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Book Synopsis Hypoxia by : Robert C. Roach

Download or read book Hypoxia written by Robert C. Roach and published by Springer Science & Business Media. This book was released on 2002-01-31 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypoxia remains a constant threat throughout life. It is for this reason that the International Hypoxia Society strives to maintain a near quarter century tradition of presenting a stimulating blend of clinical and basic science discussions. International experts from many fields have focused on the state-of-the-art discoveries in normal and pathophysiological responses to hypoxia. Topics in this volume include gene-environment interactions, a theme developed in both a clinical context regarding exercise and hypoxia, as well as in native populations living in high altitudes. Furthermore, experts in the field have combined topics such as skeletal muscle angiogenesis and hypoxia, high altitude pulmonary edema, new insights into the biology of the erythropoietin receptor, and the latest advances in cardiorespiratory control in hypoxia. This volume explores the fields of anatomy, cardiology, biological transport, and biomedical engineering among many others.

Regulation of Tissue Oxygenation, Second Edition

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Publisher : Biota Publishing
ISBN 13 : 1615047212
Total Pages : 117 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Regulation of Tissue Oxygenation, Second Edition by : Roland N. Pittman

Download or read book Regulation of Tissue Oxygenation, Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Characterization of Hypoxia

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Publisher :
ISBN 13 :
Total Pages : 192 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Characterization of Hypoxia by :

Download or read book Characterization of Hypoxia written by and published by . This book was released on 1999 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oxygen Transport to Tissue XXXVII

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Publisher : Springer
ISBN 13 : 1493930230
Total Pages : 537 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Oxygen Transport to Tissue XXXVII by : Clare E. Elwell

Download or read book Oxygen Transport to Tissue XXXVII written by Clare E. Elwell and published by Springer. This book was released on 2016-01-18 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the refereed contributions from the 42nd annual meeting of ISOTT. The annual meetings of ISOTT bring together scientists from various fields (medicine, physiology, mathematics, biology, chemistry, physics, engineering, etc.) in a unique international forum. ISOTT conferences are a place where an atmosphere of interaction is created, where many questions are asked after each presentation and lively discussions occur at a high scientific level. This vivid interaction is the main motivation for members to participate and gain new ideas and knowledge in the broad field of oxygen transport to tissue. The papers in this volume summarize some of the outstanding contributions from the 42nd annual meeting, which included sessions on: cellular hypoxia and mitochondria; blood substitutes and oxygen therapeutics; oxygen transport in critical care medicine and disease; muscle oxygenation; multi modal imaging techniques; brain oxygenation and imaging; optical techniques for oxygen measurement; microcirculation; mathematical modelling of oxygen transport; and cancer metabolism.

Photodynamic Therapy in Veterinary Medicine: From Basics to Clinical Practice

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Publisher : Springer
ISBN 13 : 3319450077
Total Pages : 228 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Photodynamic Therapy in Veterinary Medicine: From Basics to Clinical Practice by : Fábio Parra Sellera

Download or read book Photodynamic Therapy in Veterinary Medicine: From Basics to Clinical Practice written by Fábio Parra Sellera and published by Springer. This book was released on 2017-02-27 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This pioneering book offers an introduction to photodynamic therapy, a promising new approach in the treatment of complex diseases like cancer and microbial infections in animals. Addressing all aspects, ranging from basics to clinical practice, it presents the history and fundamentals of photodynamic therapy for non-experts. It includes a collection of basic and clinical studies in cancer and infectious diseases, as well as illustrations of successful treatment procedures and future perspectives and innovative applications involving nanotechnology and advanced drug delivery. This valuable resource offers readers insights into how the therapy works and how to apply it effectively in daily practice.

Low-Oxygen Stress in Plants

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Publisher : Springer Science & Business Media
ISBN 13 : 3709112540
Total Pages : 426 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Low-Oxygen Stress in Plants by : Joost T. van Dongen

Download or read book Low-Oxygen Stress in Plants written by Joost T. van Dongen and published by Springer Science & Business Media. This book was released on 2014-01-17 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last ten years, knowledge about the multitude of adaptive responses of plants to low oxygen stress has grown immensely. The oxygen sensor mechanism has been discovered, the knowledge about the interaction network of gene expression is expanding and metabolic adaptations have been described in detail. Furthermore, morphological changes were investigated and the regulative mechanisms triggered by plant hormones or reactive oxygen species have been revealed. This book provides a broad overview of all these aspects of low oxygen stress in plants. It integrates knowledge from different disciplines such as molecular biology, biochemistry, ecophysiology and agricultural / horticultural sciences to comprehensively describe how plants cope with low oxygen stress and discuss its ecological and agronomical consequences. This book is written for plant scientists, biochemists and scientists in agriculture and ecophysiology.

Hypoxia and Human Diseases

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Publisher : BoD – Books on Demand
ISBN 13 : 9535128957
Total Pages : 456 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Hypoxia and Human Diseases by : Jing Zheng

Download or read book Hypoxia and Human Diseases written by Jing Zheng and published by BoD – Books on Demand. This book was released on 2017-02-01 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a total of 21 chapters, each of which was written by experts in the corresponding field. The objective of this book is to provide a comprehensive and updated overview of cellular and molecular mechanisms underlying hypoxia's impacts on human health, as well as current advances and future directions in the detection, recognition, and management of hypoxia-related disorders. This collection of articles provides a clear update in the area of hypoxia research for biomedical researchers, medical students, nurse practitioners, and practicing clinicians in the fields of high altitude biology, cardiovascular biology and medicine, tumor oncology, obstetrics, pediatrics, and orthodontics and for others who may be interested in hypoxia.

Oxygen Transport to Tissue XXVI

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Publisher : Springer Science & Business Media
ISBN 13 : 0387262067
Total Pages : 390 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Oxygen Transport to Tissue XXVI by : Paul Okunieff

Download or read book Oxygen Transport to Tissue XXVI written by Paul Okunieff and published by Springer Science & Business Media. This book was released on 2006-06-18 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Society of Oxygen Transport to Tissue (ISOTT) was founded in 1973 to provide a forum for bioengineers, basic scientists, physiologists, and physicians to discuss new data, original theories, new interpretations of old data, and new technologies for the measurement of oxygen. At each annual meeting all posters are presented orally along with plenary lectures, and all presentations are given in a general session attended by everyone. Each meeting has had a specific focus, ranging from neonatology to physical chemistry to cancer biology. The Society has helped to build many careers, through opportunities to meet leaders in the field, and through awards made to young physicians and scientists. The Society also, through cross fertilization of ideas and scientific comradery, has inspired many breakthroughs in clinical medicine that now benefit mankind. I find myself president of the society after having been a winner of the Melvin Knisely Award for young scientists, in 1991. The 2003 meeting emphasized the role of oxygen and oxygen measurement in tumor growth, metastasis, physiology, and treatment resistance. Additionally, however, completely novel approaches to measurement of tissue oxygen were presented (notably work by Dr. Takahashi) and molecular methods for estimating tissue oxygen were evaluated. Papers discussing other aspects of oxygen measurement and pathophysiology were presented including in vivo ESR spectroscopy (notably including Dr. Swartz and colleagues), exercise physiology, organ transplant outcome (discussed by Dr. Cicco, our 2004 president), circulatory physiology, and cerebral oxygenation (notably including Dr. Chance).

Tumor Microenvironment and Cellular Stress

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Publisher : Springer Science & Business Media
ISBN 13 : 146145915X
Total Pages : 290 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Tumor Microenvironment and Cellular Stress by : Constantinos Koumenis

Download or read book Tumor Microenvironment and Cellular Stress written by Constantinos Koumenis and published by Springer Science & Business Media. This book was released on 2013-11-23 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness, cell viability, genomic instability and more. Additional topics include identifying common pathways that are potential candidates for therapeutic intervention, which will stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery.

Practitioner’s Guide to Clinical Neuropsychology

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Publisher : Springer Science & Business Media
ISBN 13 : 1461524806
Total Pages : 399 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Practitioner’s Guide to Clinical Neuropsychology by : Robert M. Anderson Jr.

Download or read book Practitioner’s Guide to Clinical Neuropsychology written by Robert M. Anderson Jr. and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author has written an easily accessible summary of neuropsychological tests, neuropsychiatric disorders, and the relationships of test performance to disorder and treatment strategy. This ready reference provides neuropsychologists with an understanding of the medical context within which neuropsychological evaluation and psychosocial therapy takes place.

Mitochondrial Dysfunction in Neurodegenerative Disorders

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Publisher : Springer
ISBN 13 : 9780857297006
Total Pages : 242 pages
Book Rating : 4.2/5 (97 download)

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Book Synopsis Mitochondrial Dysfunction in Neurodegenerative Disorders by : Amy Katherine Reeve

Download or read book Mitochondrial Dysfunction in Neurodegenerative Disorders written by Amy Katherine Reeve and published by Springer. This book was released on 2011-12-09 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New research has stimulated a growing interest in mitochondrial involvement in neurodegenerative disorders such as Parkinson’s disease, Alzheimer’s disease and multiple sclerosis and the mechanisms which lead from mitochondrial dysfunction to neurodegeneration. Mitochondrial Dysfunction in Neurodegenerative Disorders brings together contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of these diseases, guiding the reader through the basic functions of mitochondria and the mechanisms that lead to their dysfunction, to the consequences of this dysfunction on neuronal function before finishing with the modelling of these disorders and discussion of new potential therapeutic targets. Mitochondrial Dysfunction in Neurodegenerative Disorders provides an accessible, authoritative guide to this important area for neurologists; research and clinical neuroscientists; neuropathologists; and residents with an interest in clinical research.

Make Life Visible

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Publisher : Springer Nature
ISBN 13 : 9811379084
Total Pages : 292 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Make Life Visible by : Yoshiaki Toyama

Download or read book Make Life Visible written by Yoshiaki Toyama and published by Springer Nature. This book was released on 2019-10-02 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.

Physiologic and Pathologic Angiogenesis

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Publisher : BoD – Books on Demand
ISBN 13 : 9535130234
Total Pages : 466 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Physiologic and Pathologic Angiogenesis by : Dan Simionescu

Download or read book Physiologic and Pathologic Angiogenesis written by Dan Simionescu and published by BoD – Books on Demand. This book was released on 2017-04-05 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that this book will become a source of inspiration and novel ideas for all.

Hypoxia and Cancer Metastasis

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Publisher : Springer
ISBN 13 : 3030127346
Total Pages : 160 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Hypoxia and Cancer Metastasis by : Daniele M. Gilkes

Download or read book Hypoxia and Cancer Metastasis written by Daniele M. Gilkes and published by Springer. This book was released on 2019-06-14 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book is an attempt to provide a detailed review of studies that clarify our current understanding of the role of hypoxia in the progression of primary cancer to metastatic disease. It will enable researchers to discover the critical cellular changes that occur under hypoxic conditions and play a role in metastatic dissemination, from the activation of hypoxia-inducible factors, HIF-1 and HIF-2, to the transcriptional profile changes that occur in cancer cells and promote cancer cell survival under detrimental conditions. Readers will discover the methods and challenges involved in imaging and quantifying the degree of hypoxia in a primary tumor. We will provide an understanding of the hypoxia-induced phenotypes that influence heterogeneity, alter the secretome and tumor microenvironment, modify cellular metabolism, and promote immune suppression and resistance to chemotherapy. Finally, we will uncover the therapeutic strategies that are being devised to target the hypoxic microenvironment in the hopes of preventing metastasis and improving the efficacy of standard-of-care cancer treatments. This work is an up to date source of information on the challenges and complexity of the hypoxic tumor microenvironment. Basic and translational scientists, post-doctoral fellows, graduate students, and those interested in how tumors metastasize will find this book a reference that details how hypoxia influences metastatic disease.

Multivariate Analysis of Ecological Data with ade4

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Publisher : Springer
ISBN 13 : 1493988506
Total Pages : 329 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Multivariate Analysis of Ecological Data with ade4 by : Jean Thioulouse

Download or read book Multivariate Analysis of Ecological Data with ade4 written by Jean Thioulouse and published by Springer. This book was released on 2018-11-08 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the ade4 package for R which provides multivariate methods for the analysis of ecological data. It is implemented around the mathematical concept of the duality diagram, and provides a unified framework for multivariate analysis. The authors offer a detailed presentation of the theoretical framework of the duality diagram and also of its application to real-world ecological problems. These two goals may seem contradictory, as they concern two separate groups of scientists, namely statisticians and ecologists. However, statistical ecology has become a scientific discipline of its own, and the good use of multivariate data analysis methods by ecologists implies a fair knowledge of the mathematical properties of these methods. The organization of the book is based on ecological questions, but these questions correspond to particular classes of data analysis methods. The first chapters present both usual and multiway data analysis methods. Further chapters are dedicated for example to the analysis of spatial data, of phylogenetic structures, and of biodiversity patterns. One chapter deals with multivariate data analysis graphs. In each chapter, the basic mathematical definitions of the methods and the outputs of the R functions available in ade4 are detailed in two different boxes. The text of the book itself can be read independently from these boxes. Thus the book offers the opportunity to find information about the ecological situation from which a question raises alongside the mathematical properties of methods that can be applied to answer this question, as well as the details of software outputs. Each example and all the graphs in this book come with executable R code.

A Handbook of Statistical Analyses using R

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Publisher : CRC Press
ISBN 13 : 1482204592
Total Pages : 447 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis A Handbook of Statistical Analyses using R by : Torsten Hothorn

Download or read book A Handbook of Statistical Analyses using R written by Torsten Hothorn and published by CRC Press. This book was released on 2014-05-30 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Like the best-selling first two editions, A Handbook of Statistical Analyses using R, Third Edition provides an up-to-date guide to data analysis using the R system for statistical computing. The book explains how to conduct a range of statistical analyses, from simple inference to recursive partitioning to cluster analysis.New to the Third Edition

Tumor Oxygenation

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Author :
Publisher : Lubrecht & Cramer, Limited
ISBN 13 :
Total Pages : 348 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Tumor Oxygenation by : Peter Vaupel

Download or read book Tumor Oxygenation written by Peter Vaupel and published by Lubrecht & Cramer, Limited. This book was released on 1995 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: