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Characterization Of Escherichia Coli Ubix Saccharomyces Cerevisiae Pad1 And Ydr539w And A Complex Of Polypeptides Involved In Coenzyme Q Biosynthesis
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Book Synopsis Characterization of Escherichia Coli UbiX, Saccharomyces Cerevisiae PAD1 and YDR539W, and a Complex of Polypeptides Involved in Coenzyme Q Biosynthesis by : Melissa Gulmezian
Download or read book Characterization of Escherichia Coli UbiX, Saccharomyces Cerevisiae PAD1 and YDR539W, and a Complex of Polypeptides Involved in Coenzyme Q Biosynthesis written by Melissa Gulmezian and published by . This book was released on 2006 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Coenzyme Q Biosynthesis in Saccharomyces Cerevisiae by : Peter Kai Chong Gin
Download or read book Coenzyme Q Biosynthesis in Saccharomyces Cerevisiae written by Peter Kai Chong Gin and published by . This book was released on 2005 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Coenzyme Q Biosynthesis in Saccharomyces Cerevisiae by : Christopher Michael Allan
Download or read book Coenzyme Q Biosynthesis in Saccharomyces Cerevisiae written by Christopher Michael Allan and published by . This book was released on 2014 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coenzyme Q (Q or ubiquinone) is a redox-active lipid consisting of a fully substituted benzoquinone ring and a lipophilic polyisoprenoid moiety which serves to anchor Q in biological membranes. Q is essential to mitochondrial electron transport where it accepts electrons from NADH or succinate at complexes I and II respectively, and donates them to cytochrome c at complex III. In the yeast Saccharomyces cerevisiae Q is synthesized by the products of eleven nuclear-encoded genes: COQ1-COQ9, YAH1, and ARH1. The product of an additional gene, COQ10, is not required for the biosynthesis of Q but is necessary for its function in efficient electron transport and respiration. Chapter 2 investigates the role of Coq10p in both mitochondrial respiration and de novo Q synthesis through analysis of coq10 null mutants and the Coq10p prokaryotic homolog CC1736. Expression of CC1736 harboring a mitochondrial leader sequence in yeast coq10 mutants restored respiration and growth on a non-fermentable carbon source, and binding assays demonstrated that CC1736 is capable of binding different isoforms of Q and a late-stage Q biosynthetic intermediate. Lipid analysis of the coq10 null mutant revealed significantly decreased de novo Q synthesis when compared to wild type, especially at early-log phase, indicating Coq10p is required for efficient de novo biosynthesis of Q. Chapter 3 describes characterization of a mitochondrial multi-subunit Coq polypeptide complex required for Q biosynthesis. The complex was purified by tandem affinity purification of particular dual-tagged Coq proteins and Western blotting analysis of purified eluates showed that the biosynthetic complex includes Coq3p, Coq4p, Coq5p, Coq6p, Coq7p, and Coq9p. In addition, Coq8p was observed to co-purify with tagged Coq6p but not other tagged Coq proteins. The purified eluates were also subject to proteomic analysis to identify potentially novel binding partners, identifying two proteins, Ilv6p and YLR290C. Lipid analysis of the corresponding null mutants revealed that the ylr290c mutant has significantly reduced de novo Q synthesis, while the ilv6 mutant synthesizes wild-type levels of Q. Tandem affinity purification of tagged YLR290C demonstrated that it is associated with Coq4p, Coq5p, and Coq7p.
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2007 with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biotechnology in Japan written by and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Flavin-based Catalysis by : Radek Cibulka
Download or read book Flavin-based Catalysis written by Radek Cibulka and published by Wiley-VCH. This book was released on 2021-09-07 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book gives a unique overview of this rapidly developing research field, presenting structures and properties of flavin derivatives as well as their proven application as bioinspired catalysts in various organocatalytic, biocatalytic, and photocatalytic reactions.
Book Synopsis Handbook of Vanilla Science and Technology by : Daphna Havkin-Frenkel
Download or read book Handbook of Vanilla Science and Technology written by Daphna Havkin-Frenkel and published by John Wiley & Sons. This book was released on 2018-09-24 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated guide to the production, science, and uses of vanilla Vanilla is a flavor and fragrance in foods, cosmetics, pharmaceuticals, and a wealth of other products. Now in its second edition, the Handbook of Vanilla Science and Technology provides a comprehensive and updated review of the science and technology used in these items’ production and supply. Featuring contributions from an international range of experts, this revised edition covers a multitude of topics, including agricultural production, global markets, analytical methods, sensory analysis, food and fragrance applications, organic farming and fair trade, botanical diseases, and novel uses. The Handbook of Vanilla Science and Technology, Second Edition is a vital resource for producers, distributors, and scientists involved in vanilla’s growth and utilization, and offers readers: A guide to the cultivation, extraction, analysis, DNA sequencing, and marketing of vanilla Information on the production of vanilla in a range of countries such as Mexico, Australia, Costa Rica, and India Guidelines on the quality control of vanilla beans and extracts Information on fair trade and the future of vanilla
Book Synopsis Biotechnology of Natural Products by : Wilfried Schwab
Download or read book Biotechnology of Natural Products written by Wilfried Schwab and published by Springer. This book was released on 2017-11-16 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text comprehensively covers the analysis, enzymology, physiology and genetics of valuable natural products used in the food industry that are attractive targets for biotechnological production. The focus is on the recent advances made to achieve this goal. This unique work is the first book to focus on biotechnological production of important natural products in food additives, fragrances and flavorings, and other bioactive compounds in food. The chapters offer a deep insight into modern research and the development of low molecular weight natural products. Biotechnology of Natural Products covers products in the Phenolic, Terpenoid, and Alkaloid categories, providing a full overview of the biotechnology of food additives and other low molecular weight natural products. Gene clustering and the evolution of pathways are covered, as well as future perspectives on the topic. Due to limited oil resources and increasing consumer demand for naturalness, bioprocesses are increasingly needed to meet these requirements. Novel sophisticated technologies have facilitated the elucidation of new chemical molecules, their biosynthetic pathways and biological functions. This book provides researchers with a full overview of the technologies and processes involved in the biotechnology of natural products.
Book Synopsis Natural Flavors and Fragrances by : Carl Frey
Download or read book Natural Flavors and Fragrances written by Carl Frey and published by . This book was released on 2005 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the development of synthetic organic chemistry techniques in the early 19th century the world of synthetic F&F materials began and expanded, but it has not totally replaced natural F&F. A growing segment of the public prefers natural foods to foods containing artificial additives, and will pay a premium for natural foods. While modern synthetic methods permit the economical production of artificial F&F on a large scale, the natural F&F industry remains important. Why is this so? How do the chemical, biological, and agricultural sciences support the natural F&F industry? What is the state of current natural F&F research? These are questions this volume attempts to address. Even considering only the value of F&F derived from essential oils, natural F&F constitute approximately a $2 billion annual business. The impact of F&F is best appreciated when you consider that a flavor or fragrance typically contributes only a very small part, both in cost and volume, to a finished product. Many analytical tools available do not have a detector that is as sensitive to taste or odor as a human (or many animals for that matter). The challenge for researchers is to sift F&F information from all the data obtained from the various analytical techniques. The intent of this book is to give the reader and appreciation for the many facets of the chemistry, analysis and production of natural flavors and fragrances. It is a field where each one of us who can smell and taste are active participants. New foods, plants, processes, packages and aromas are developed each day. Keeping researchers abreast of the many new facets of the natural F&F field have led to development of this chapter and the ACS symposium that served as the basis of this book.
