Marijuana As Medicine?

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Author :
Publisher : National Academies Press
ISBN 13 : 0309065313
Total Pages : 216 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Marijuana As Medicine? by : Institute of Medicine

Download or read book Marijuana As Medicine? written by Institute of Medicine and published by National Academies Press. This book was released on 2000-12-30 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some people suffer from chronic, debilitating disorders for which no conventional treatment brings relief. Can marijuana ease their symptoms? Would it be breaking the law to turn to marijuana as a medication? There are few sources of objective, scientifically sound advice for people in this situation. Most books about marijuana and medicine attempt to promote the views of advocates or opponents. To fill the gap between these extremes, authors Alison Mack and Janet Joy have extracted critical findings from a recent Institute of Medicine study on this important issue, interpreting them for a general audience. Marijuana As Medicine? provides patientsâ€"as well as the people who care for themâ€"with a foundation for making decisions about their own health care. This empowering volume examines several key points, including: Whether marijuana can relieve a variety of symptoms, including pain, muscle spasticity, nausea, and appetite loss. The dangers of smoking marijuana, as well as the effects of its active chemical components on the immune system and on psychological health. The potential use of marijuana-based medications on symptoms of AIDS, cancer, multiple sclerosis, and several other specific disorders, in comparison with existing treatments. Marijuana As Medicine? introduces readers to the active compounds in marijuana. These include the principal ingredient in Marinol, a legal medication. The authors also discuss the prospects for developing other drugs derived from marijuana's active ingredients. In addition to providing an up-to-date review of the science behind the medical marijuana debate, Mack and Joy also answer common questions about the legal status of marijuana, explaining the conflict between state and federal law regarding its medical use. Intended primarily as an aid to patients and caregivers, this book objectively presents critical information so that it can be used to make responsible health care decisions. Marijuana As Medicine? will also be a valuable resource for policymakers, health care providers, patient counselors, medical faculty and studentsâ€"in short, anyone who wants to learn more about this important issue.

Refractory Migraine

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Author :
Publisher : Oxford University Press
ISBN 13 : 0199745560
Total Pages : 495 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Refractory Migraine by : Elliot A. Schulman, FACP, MD

Download or read book Refractory Migraine written by Elliot A. Schulman, FACP, MD and published by Oxford University Press. This book was released on 2010-08-05 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: A must-have book for any health professional who treats patients with headache disorders, Refractory Migraine is written by international experts from the world's top headache centers. It describes how they approach the treatment of migraine patients who continue to suffer despite appropriate medical treatment. First, it highlights current ideas about the definition and characterization of refractory migraine, and reviews underlying causes and contributing factors. Then, individual chapters cover every important aspect of migraine treatment with the focus entirely on refractory forms of the disorder. Its many features include detailed algorithms for outpatient and inpatient withdrawal from overused medications, innovative drug therapy and nonpharmacological treatments, a list of questions to ask before deciding to try hormonal therapies, and detailed descriptions of how to recognize and interact with patients who have challenging personality disorders or concomitant psychiatric problems. We're confident you'll often turn to this book for advice about challenges in migraine management. When you do, the bulleted lists and boxes that highlight and condense the main messages of each chapter put the information you need at your fingertips. If you treat patients with migraine, you will recognize many of the challenging situations and topics covered in this book - and you will be encouraged by the innovative and resourceful therapeutic strategies suggested by seasoned headache doctors with a wealth of clinical experience. Readable, comprehensive and up to date, this book gives you access to ingenious treatment approaches developed and refined in specialty headache clinics that regularly - and successfully - treat patients with refractory headache problems. When you meet the next migraine patient who says "I've tried it all, and nothing works", you will know where to go for practical advice about what to do next.

The Health Effects of Cannabis and Cannabinoids

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Author :
Publisher : National Academies Press
ISBN 13 : 0309453070
Total Pages : 487 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis The Health Effects of Cannabis and Cannabinoids by : National Academies of Sciences, Engineering, and Medicine

Download or read book The Health Effects of Cannabis and Cannabinoids written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-03-31 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Compounded Topical Pain Creams

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Publisher : National Academies Press
ISBN 13 : 030967218X
Total Pages : 353 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Compounded Topical Pain Creams by : National Academies of Sciences, Engineering, and Medicine

Download or read book Compounded Topical Pain Creams written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-07-21 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain is both a symptom and a disease. It manifests in multiple forms and its treatment is complex. Physical, social, economic, and emotional consequences of pain can impair an individual's overall health, well-being, productivity, and relationships in myriad ways. The impact of pain at a population level is vast and, while estimates differ, the Centers for Disease Control and Prevention reported that 50 million U.S. adults are living in pain. In terms of pain's global impact, estimates suggest the problem affects approximately 1 in 5 adults across the world, with nearly 1 in 10 adults newly diagnosed with chronic pain each year. In recent years, the issues surrounding the complexity of pain management have contributed to increased demand for alternative strategies for treating pain. One such strategy is to expand use of topical pain medicationsâ€"medications applied to intact skin. This nonoral route of administration for pain medication has the potential benefit, in theory, of local activity and fewer systemic side effects. Compounding is an age-old pharmaceutical practice of combining, mixing, or adjusting ingredients to create a tailored medication to meet the needs of a patient. The aim of compounding, historically, has been to provide patients with access to therapeutic alternatives that are safe and effective, especially for people with clinical needs that cannot otherwise be met by commercially available FDA-approved drugs. Compounded Topical Pain Creams explores issues regarding the safety and effectiveness of the ingredients in these pain creams. This report analyzes the available scientific data relating to the ingredients used in compounded topical pain creams and offers recommendations regarding the treatment of patients.

Cluster Headache and Related Conditions

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Publisher :
ISBN 13 :
Total Pages : 334 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cluster Headache and Related Conditions by : Jes Olesen

Download or read book Cluster Headache and Related Conditions written by Jes Olesen and published by . This book was released on 1999 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cluster headache affects 0.1% of the population and is a severe form of primary headache. This volume of Frontiers in Headache Research is the only up-to-date and comprehensive review of the condition and its related disorders. The book begins with a discussion of the basic circadian biology of the condition followed by an overview of relevant epidemiological studies. Cluster headache is then described in comparison with related disorders, including paroxysmal hemicrania, SUNCT, hemicrania continua and hypnic headache, and the system of classification discussed. The volume then moves on to look at the wealth of basic research into cluster headache, including, animal studies, work on the autonomic nervous system in man, neuropeptide research, studies of biological rhythms, the associated endocrinology, information derived from neuroimaging and the influence of genetic factors. The final sections of the book examine acute treatment, prophylaxis, the potential for surgical treatment and the opportunities for further innovative therapies. The contributing authors are all international specialists in this field.

Herbal Home Remedies

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Author :
Publisher : Lotus Press
ISBN 13 : 9788183820547
Total Pages : 162 pages
Book Rating : 4.8/5 (25 download)

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Book Synopsis Herbal Home Remedies by : Dr. Rajeev Sharma

Download or read book Herbal Home Remedies written by Dr. Rajeev Sharma and published by Lotus Press. This book was released on 2006 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pathophysiology of Headaches

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Author :
Publisher : Springer
ISBN 13 : 3319156217
Total Pages : 277 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Pathophysiology of Headaches by : Messoud Ashina

Download or read book Pathophysiology of Headaches written by Messoud Ashina and published by Springer. This book was released on 2015-04-14 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed overview of the current state of knowledge regarding the pathophysiology of both primary headaches – migraine, tension-type headache (TTH), and cluster headache – and the very important and frequent type of secondary headache, medication overuse headache (MOH). After an introductory chapter describing relevant neuroanatomy and vascular anatomy, the evidence gained from animal models regarding the pathophysiology of migraine and the other primary headaches is reviewed. Knowledge of the genetic component in the different types of headache is then examined with reference to recent evidence, for example regarding the implication of the trigeminovascular system and cortical spreading depression in migraine. Detailed information is provided on insights into primary headaches from imaging studies, including functional magnetic resonance imaging and positron emission tomography and on their neurophysiology and biochemistry. A further series of important chapters describe present knowledge of the pathophysiology of each specific type of headache and consider future directions. Written by acknowledged experts in their fields from Europe and the United States, clinicians and students will find Pathophysiology of Headaches to be an excellent source of up-to-date information on why patients experience headaches. In addition, it will be of value for pain researchers investigating the underlying mechanisms of headache.

Cannabinoids and Pain

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Author :
Publisher : Springer Nature
ISBN 13 : 3030691861
Total Pages : 339 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Cannabinoids and Pain by : Samer N. Narouze

Download or read book Cannabinoids and Pain written by Samer N. Narouze and published by Springer Nature. This book was released on 2021-07-01 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a well-balanced view of the potential medical use of cannabinoids in pain. It comprehensively covers the current challenges with medical cannabis utilization and provides recommendations for research and future directions. Organized into nine sections, the book begins with an introduction to medical cannabis, including its history, regulations, and the general attitudes of pain physicians on cannabis. Section two explores the biological effects of marijuana via the endocannabinoid system and its complex structure of receptors and enzymes. Sections three, four, and five then delve further into pharmacology and the mechanisms of action applicable to cannabinoids in managing pain. Timely and socially conscious, section six examines the benefits of substituting opioids with cannabinoids for preoperative management. Echoing the book's well-rounded content, sections seven and eight consider the challenges with medical cannabis, including safety and quality control, brain development risks, vaping hazards, and withdrawal. The book then closes with a look at the future of cannabis in medical research. Thoroughly and equitably composed, Cannabinoids and Pain is an invaluable resource for primary care physicians, pain and palliative care physicians, and oncologists.

Medical Marijuana

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Author :
Publisher : Penguin
ISBN 13 : 0593190246
Total Pages : 305 pages
Book Rating : 4.5/5 (931 download)

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Book Synopsis Medical Marijuana by : Mikhail Kogan, M.D.

Download or read book Medical Marijuana written by Mikhail Kogan, M.D. and published by Penguin. This book was released on 2023-03-07 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential guide to understanding the health benefits of marijuana and CBD Marijuana has been used for thousands of years as a medicine, but pot has been illegal in the United States for most of our lives. Almost all states have now legalized its medical use, and many consumers and physicians are exploring it as an alternative to conventional treatments. There’s substantial evidence that marijuana (cannabis) is a safe and effective treatment for chronic pain, chemo side effects, sleep and mood disorders, MS, and Parkinson’s disease, among others. But there’s also misinformation about marijuana on social media. And most physicians have limited knowledge on the subject, while dispensary staff (aka “budtenders”) lack medical training. Mikhail Kogan, MD, a renowned expert on medical marijuana, has found that cannabinoids (THC, CBD, hemp, and other cannabis products) can often be more beneficial, have fewer side effects, and be safer than many conventional medications, including opioids and other painkillers. But different ailments require different strains, doses, and routes of delivery. Medical Marijuana demystifies marijuana and other forms of cannabis in a user-friendly guide that will help readers: • Understand how marijuana morphed from the days of “Reefer Madness” to being hailed as a wonder weed • Navigate the complex medical and legal world of marijuana • Understand the risks and benefits of THC, CBD, and other cannabis products • Evaluate the pros and cons of inhaled and other routes of delivery: edibles, topicals, and even suppositories • Find a doctor who can recommend medical cannabis • Choose a reliable dispensary • Learn how to evaluate labels on cannabis products • Discover cost-saving strategies since medical marijuana isn’t covered by health insurance With real-life patients’ stories woven throughout the book, simple explanatory graphics, and the most up-to-date information, this is the definitive guide to the wide-ranging benefits of medical marijuana and other forms of cannabis.

The CBD Oil Solution

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Author :
Publisher : Penguin
ISBN 13 : 1465487123
Total Pages : 228 pages
Book Rating : 4.4/5 (654 download)

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Book Synopsis The CBD Oil Solution by : Rachna Patel

Download or read book The CBD Oil Solution written by Rachna Patel and published by Penguin. This book was released on 2019-03-05 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get healthy, not high. Discover the calming, pain-relieving effects of CBD oil and try recipes for delicious CBD-infused edibles and DIY self-care products. CBD oil, or cannabidiol, is a nonpsychoactive compound found in cannabis that boasts serious health benefits for your mind and body. It's been shown to effectively alleviate pain, lessen anxiety, reduce inflammation, and improve overall well-being. Get the facts about CBD oil, and experience the benefits of this healing product with edibles and self-care products you can make yourself and customize to meet your needs. Dr. Rachna Patel, a recognized expert in the field of medical cannabis, separates fact from fiction in The CBD Oil Solution, sharing everything you need to know about CBD, including: • Explanation of CBD oil--what it is, how it works, and how it differs from THC • What ailments can be treated with CBD oil--and how to decide if CBD is right for you • What to consider when purchasing CBD oil, including how to read a product label • Information on proper dosing and use • More than 40 recipes and remedies--from drinks and desserts to lotions and lip balms--that can be customized for your needs.

Cannabis

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Publisher : MDPI
ISBN 13 : 3039439952
Total Pages : 204 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Cannabis by : Marco Colizzi

Download or read book Cannabis written by Marco Colizzi and published by MDPI. This book was released on 2021-02-05 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the years, there has been increasing interest into the public health impact of cannabis use, especially by young adults. This follows the evidence of a growing prevalence of regular cannabis use worldwide, with approximately 200 million users. Recreational cannabis use, especially a frequent use of products with high levels of its main psychoactive ingredient delta-9-tetrahydrocannabinol (Δ 9-THC), can cause dependence and have transient and long-lasting detrimental mental health effects, also negatively impacting cognitive processing and brain function and metabolism. In regular users, the development of tolerance to some of the effects of cannabis, especially the pleasurable ones, may lead to progressively heavier use in order to obtain the same effects in terms of their intensity, with higher health risks. However, the Cannabis Sativa plant contains different chemicals with different potential effects. In this regard, cannabidiol has gained interest because of its potential therapeutic properties, in line with evidence that CBD and Δ9-THC may exhibit opposite effects at the cannabinoid receptor type 1 (CB1), Δ9-THC being a partial agonist and CBD an antagonist/inverse agonist. Different cannabinoids may modulate human brain function and behavior in different ways, with different risk–benefit profiles.

The Science of Medical Cannabis

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Publisher :
ISBN 13 : 9781536145663
Total Pages : 144 pages
Book Rating : 4.1/5 (456 download)

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Book Synopsis The Science of Medical Cannabis by : David S. Younger

Download or read book The Science of Medical Cannabis written by David S. Younger and published by . This book was released on 2018-11-14 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cultural, scientific and legislative divide created by vigorous debates over the legalization of medical marijuana is giving way to a new synergy among community stakeholders across the United States. The goal is to improve access to medical marijuana for patients with refractory debilitating neurological disorders, cancer, and chronic pain as an alternative to ineffective pharmacotherapy and potentially addictive pain medications. The ultimate test of our nations resolve to ensure the welfare of our sickest patients is the enactment and implement of effective public health reform in the area of medical marijuana, also known as medical cannabis.This book evolved out of the present need for a definitive volume on the science and public health aspects of medical cannabis to fuel this national narrative. The ethnographic research presented in the concluding chapter was inspired by Professor Miriam W. Boeri and colleagues, at Bentley University in Waltham, MA. They examined views of community stakeholders including medical marijuana dispensary entrepreneurs, health care professionals, and patients in a state that legalized medical marijuana in 2013, yet there continued to be confusion and misunderstandings in the interpretation and implementation of medical marijuana guidelines during the period of policy shifts. Apparent gaps in policy development and implementation signaled the urgency for a comparison study addressing stakeholder views in New York State, where its medical marijuana program has legally dispensed the drug since 2014. The resulting pilot study was carried out in the Division of Health Policy and Management of the City University of New York School of Public Health. The research model incorporated ethnographic and grounded methodologies to detail the views of physicians, pharmacists, educators, patients, and entrepreneur stakeholders; with triangulation of data and application of dominant themes into a socioecological framework model to identify areas of public health policy reform. The findings of this study detail that New York, like other states that recently legalized the dispensation of medical marijuana, faces challenges beyond policy transparency, communication and education explicitly to improve the implementation process for applying and registering medical cannabis dispensaries, referring physicians, and qualified patient recipients.Ken Langone, Chairman of the Board of New York University Langone Health, and Steven Galetta, Chair of Neurology in the School of Medicine, where the authors is senior staff in neuroepidemiology, motivated him to pursue doctoral training in Health Policy and Management. The author has had the good fortune of interacting with thought-provoking medical students, neurology trainees, public health doctoral students, and professors who reinforce the high ethical standards in medical and public health practice and research. However, his patients still educate him in empathy and humanity. The author is grateful to his family, including his spouse Holly and sons Adam and Seth, who serve as his daily compass, encouraging him to take on projects that promote core values of medicine and humanity.

Heal Your Headache

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Author :
Publisher : Workman Publishing
ISBN 13 : 0761125663
Total Pages : 272 pages
Book Rating : 4.7/5 (611 download)

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Book Synopsis Heal Your Headache by : David Buchholz

Download or read book Heal Your Headache written by David Buchholz and published by Workman Publishing. This book was released on 2002-08-12 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the breakthrough understanding that virtually all headaches are forms of migraine--because migraine is not a specific type of headache, but the built-in mechanism that causes headaches of all kinds, along with neck stiffness, sinus congestion, dizziness, and other problems--Dr. Buchholz's Heal Your Headache puts headache sufferers back in control of their lives with a simple, transforming program: Step 1: Avoid the "Quick Fix." Too often painkillers only make matters worse because of the crippling complication known as rebound. Step 2: Reduce Your Triggers. The crux of the program: a migraine diet that eliminates the foods that push headache sufferers over the top. Step 3: Raise Your Threshold. When diet and other lifestyle changes aren't enough, preventive medication can help stay the course. That's it: in three steps turn your headache problems around.

Smoke Signals

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Publisher : Simon and Schuster
ISBN 13 : 1439102619
Total Pages : 529 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis Smoke Signals by : Martin A. Lee

Download or read book Smoke Signals written by Martin A. Lee and published by Simon and Schuster. This book was released on 2013-08-13 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book the author, an investigative journalist, traces the social history of marijuana from its origins to its emergence in the 1960s as a defining force in an ongoing culture war. He describes how the illicit marijuana subculture overcame government opposition and morphed into a multibillion-dollar industry. In 1996, Californians voted to legalize marijuana for medicinal purposes. Similar laws have followed in several other states, but not without antagonistic responses from federal, state, and local law enforcement. The author draws attention to underreported scientific breakthroughs that are reshaping the therapeutic landscape: medical researchers have developed promising treatments for cancer, heart disease, Alzheimer's, diabetes, chronic pain, and many other conditions that are beyond the reach of conventional cures. This book is an examination of the medical, recreational, scientific, and economic dimensions of the world's most controversial plant.

Reader's Digest The Essential Guide to CBD

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Author :
Publisher : Simon and Schuster
ISBN 13 : 1621455076
Total Pages : 220 pages
Book Rating : 4.6/5 (214 download)

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Book Synopsis Reader's Digest The Essential Guide to CBD by : Reader's Digest and Project CBD

Download or read book Reader's Digest The Essential Guide to CBD written by Reader's Digest and Project CBD and published by Simon and Schuster. This book was released on 2021-03-23 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Reader’s Digest Essential Guide to CBD is an authoritative but user-friendly primer on CBD. CBD has splashed across the nation’s headlines, taken the country by storm, and has everyone from Coca-Cola to Starbucks considering adding this new “miracle supplement” to their drinks. But the FDA has only approved it for use in treating epilepsy in children. What is CBD, anyway? What’s the difference between CBD, THC, cannabis, hemp, and marijuana? Can CBD help me lose weight? How much CBD do I need to take to help my condition? What do I look for when buying CBD? Is it better to take CBD oil or gummies or what? The Reader’s Digest Guide to CBD will answer all of these questions and much more, including both first-person anecdotes of real people’s experiences with CBD and straightforward reporting about what studies have actually been done and what they show. Written in part by the experts at Project CBD, the book will separate fact from fiction, hype from reality.

Not Tonight

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Author :
Publisher : University of Chicago Press
ISBN 13 : 022617915X
Total Pages : 260 pages
Book Rating : 4.2/5 (261 download)

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Book Synopsis Not Tonight by : Joanna Kempner

Download or read book Not Tonight written by Joanna Kempner and published by University of Chicago Press. This book was released on 2014-10-08 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Migraine is an extraordinarily common, disabling, and painful disorder that affects over 36 million Americans and costs the US economy at least $32 billion per year. Nevertheless, it is frequently dismissed, ignored, and delegitimised. In this book, Joanna Kempner argues that this general dismissal of migraine can be traced back to the gendered social values embedded in the way we talk about, understand, and make policies for people in pain.

Clinical Practice Guidelines We Can Trust

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Author :
Publisher : National Academies Press
ISBN 13 : 030921646X
Total Pages : 217 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Clinical Practice Guidelines We Can Trust by : Institute of Medicine

Download or read book Clinical Practice Guidelines We Can Trust written by Institute of Medicine and published by National Academies Press. This book was released on 2011-06-16 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes. Clinical practice guidelines now are ubiquitous in our healthcare system. The Guidelines International Network (GIN) database currently lists more than 3,700 guidelines from 39 countries. Developing guidelines presents a number of challenges including lack of transparent methodological practices, difficulty reconciling conflicting guidelines, and conflicts of interest. Clinical Practice Guidelines We Can Trust explores questions surrounding the quality of CPG development processes and the establishment of standards. It proposes eight standards for developing trustworthy clinical practice guidelines emphasizing transparency; management of conflict of interest ; systematic review-guideline development intersection; establishing evidence foundations for and rating strength of guideline recommendations; articulation of recommendations; external review; and updating. Clinical Practice Guidelines We Can Trust shows how clinical practice guidelines can enhance clinician and patient decision-making by translating complex scientific research findings into recommendations for clinical practice that are relevant to the individual patient encounter, instead of implementing a one size fits all approach to patient care. This book contains information directly related to the work of the Agency for Healthcare Research and Quality (AHRQ), as well as various Congressional staff and policymakers. It is a vital resource for medical specialty societies, disease advocacy groups, health professionals, private and international organizations that develop or use clinical practice guidelines, consumers, clinicians, and payers.