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Cardiac Tissue Engineering
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Book Synopsis Cardiac Tissue Engineering by : Milica Radisic
Download or read book Cardiac Tissue Engineering written by Milica Radisic and published by Humana Press. This book was released on 2014-07-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac Tissue Engineering: Methods and Protocols presents a collection of protocols on cardiac tissue engineering from pioneering and leading researchers around the globe. These include methods and protocols for cell preparation, biomaterial preparation, cell seeding, and cultivation in various systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cardiac Tissue Engineering: Methods and Protocols highlights the major techniques, both experimental and computational, for the study of cardiovascular tissue engineering.
Book Synopsis Cardiac Tissue Engineering by : Smadar Cohen
Download or read book Cardiac Tissue Engineering written by Smadar Cohen and published by Springer Nature. This book was released on 2022-06-01 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac tissue engineering aims at repairing damaged heart muscle and producing human cardiac tissues for application in drug toxicity studies. This book offers a comprehensive overview of the cardiac tissue engineering strategies, including presenting and discussing the various concepts in use, research directions and applications. Essential basic information on the major components in cardiac tissue engineering, namely cell sources and biomaterials, is firstly presented to the readers, followed by a detailed description of their implementation in different strategies, broadly divided to cellular and acellular ones. In cellular approaches, the biomaterials are used to increase cell retention after implantation or as scaffolds when bioengineering the cardiac patch, in vitro. In acellular approaches, the biomaterials are used as ECM replacement for damaged cardiac ECM after MI, or, in combination with growth factors, the biomaterials assume an additional function as a depot for prolonged factor activity for the effective recruitment of repairing cells. The book also presents technological innovations aimed to improve the quality of the cardiac patches, such as bioreactor applications, stimulation patterns and prevascularization. This book could be of interest not only from an educational perspective (i.e. for graduate students), but also for researchers and medical professionals, to offer them fresh views on novel and powerful treatment strategies. We hope that the reader will find a broad spectrum of ideas and possibilities described in this book both interesting and convincing. Table of Contents: Introduction / The Heart: Structure, Cardiovascular Diseases, and Regeneration / Cell Sources for Cardiac Tissue Engineering / Biomaterials: Polymers, Scaffolds, and Basic Design Criteria / Biomaterials as Vehicles for Stem Cell Delivery and Retention in the Infarct / Bioengineering of Cardiac Patches, In Vitro / Perfusion Bioreactors and Stimulation Patterns in Cardiac Tissue Engineering / Vascularization of Cardiac Patches / Acellular Biomaterials for Cardiac Repair / Biomaterial-based Controlled Delivery of Bioactive Molecules for Myocardial Regeneration
Book Synopsis Cardiovascular Regenerative Medicine by : Vahid Serpooshan
Download or read book Cardiovascular Regenerative Medicine written by Vahid Serpooshan and published by Springer. This book was released on 2019-06-29 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of cardiovascular disease. It provides a much-needed review of the rapid development and evolution of bio-fabrication techniques to engineer cardiovascular tissues as well as their use in clinical settings. The book incorporates recent advances in the biology, biomaterial design, and manufacturing of bioengineered cardiovascular tissue with their clinical applications to bridge the basic sciences to current and future cardiovascular treatment. The book begins with an examination of state-of-the-art cellular, biomaterial, and macromolecular technologies for the repair and regeneration of diseased heart tissue. It discusses advances in nanotechnology and bioengineering of cardiac microtissues using acoustic assembly. Subsequent chapters explore the clinical applications and translational potential of current technologies such as cardiac patch-based treatments, cell-based regenerative therapies, and injectable hydrogels. The book examines how these methodologies are used to treat a variety of cardiovascular diseases including myocardial infarction, congenital heart disease, and ischemic heart injuries. Finally, the volume concludes with a summary of the most prominent challenges and perspectives on the field of cardiovascular tissue engineering and clinical cardiovascular regenerative medicine. Cardiovascular Regenerative Medicine is an essential resource for physicians, residents, fellows, and medical students in cardiology and cardiovascular regeneration as well as clinical and basic researchers in bioengineering, nanomaterial and technology, and cardiovascular biology.
Book Synopsis Myocardial Tissue Engineering by : Aldo R. Boccaccini
Download or read book Myocardial Tissue Engineering written by Aldo R. Boccaccini and published by Springer Science & Business Media. This book was released on 2011-08-30 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial tissue engineering (MTE), a concept that intends to prolong patients’ life after cardiac damage by supporting or restoring heart function, is continuously improving. Common MTE strategies include an engineered ‘vehicle’, which may be a porous scaffold or a dense substrate or patch, made of either natural or synthetic polymeric materials. The function of the substrate is to aid transportation of cells into the diseased region of the heart and support their integration. This book, which contains chapters written by leading experts in MTE, gives a complete analysis of the area and presents the latest advances in the field. The chapters cover all relevant aspects of MTE strategies, including cell sources, specific TE techniques and biomaterials used. Many different cell types have been suggested for cell therapy in the framework of MTE, including autologous bone marrow-derived or cardiac progenitors, as well as embryonic or induced pluripotent stem cells, each having their particular advantages and disadvantages. The book covers a complete range of biomaterials, examining different aspects of their application in MTE, such as biocompatibility with cardiac cells, mechanical capability and compatibility with the mechanical properties of the native myocardium as well as degradation behaviour in vivo and in vitro. Although a great deal of research is being carried out in the field, this book also addresses many questions that still remain unanswered and highlights those areas in which further research efforts are required. The book will also give an insight into clinical trials and possible novel cell sources for cell therapy in MTE.
Book Synopsis Tissue Engineering for the Heart by : Ravi Birla
Download or read book Tissue Engineering for the Heart written by Ravi Birla and published by Springer. This book was released on 2016-09-26 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the fundamentals of tissue engineering for the heart, starting with the basics of organ generation, sensors in tissue and organ fabrication, and the current state-of-the-art in stem cell engineering for the heart. With this foundation in place, the remaining chapters focus on specific aspects of the cardiovascular system, starting with heart muscle, then biological pumps, followed by bioartificial ventricles, and finally, bioartificial hearts. Throughout the course of this book, twenty-two in-depth case studies are presented. Each case study has been selected to illustrate specific design schemes for tissue and organ fabrication. This is an ideal book for upper-level undergraduate and graduate students studying tissue engineering and organ regeneration, especially those focused on cardiac regeneration. This book also: Includes twenty-two case studies that illustrate specific design schemes for engineering the heart Provides open-ended discussion questions at the end of each chapter as well as a detailed reference list to encourage further research and reading Covers the basics of organ fabrication as well as sensor technology and genetic engineering as they relate to tissue and organ fabrication
Book Synopsis Etiology and Morphogenesis of Congenital Heart Disease by : Toshio Nakanishi
Download or read book Etiology and Morphogenesis of Congenital Heart Disease written by Toshio Nakanishi and published by Springer. This book was released on 2018-06-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide novel in vitro disease models and to generate regenerative paradigms for cardiac repair and regeneration. This is the ideal resource for physician scientists and investigators looking for updates on recent investigations on the origins of congenital heart disease and potential future therapies.
Book Synopsis Cardiac Tissue Engineering by : Smadar Cohen
Download or read book Cardiac Tissue Engineering written by Smadar Cohen and published by Morgan & Claypool Publishers. This book was released on 2012-10-01 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac tissue engineering aims at repairing damaged heart muscle and producing human cardiac tissues for application in drug toxicity studies. This book offers a comprehensive overview of the cardiac tissue engineering strategies, including presenting and discussing the various concepts in use, research directions and applications. Essential basic information on the major components in cardiac tissue engineering, namely cell sources and biomaterials, is firstly presented to the readers, followed by a detailed description of their implementation in different strategies, broadly divided to cellular and acellular ones. In cellular approaches, the biomaterials are used to increase cell retention after implantation or as scaffolds when bioengineering the cardiac patch, in vitro. In acellular approaches, the biomaterials are used as ECM replacement for damaged cardiac ECM after MI, or, in combination with growth factors, the biomaterials assume an additional function as a depot for prolonged factor activity for the effective recruitment of repairing cells. The book also presents technological innovations aimed to improve the quality of the cardiac patches, such as bioreactor applications, stimulation patterns and prevascularization. This book could be of interest not only from an educational perspective (i.e. for graduate students), but also for researchers and medical professionals, to offer them fresh views on novel and powerful treatment strategies. We hope that the reader will find a broad spectrum of ideas and possibilities described in this book both interesting and convincing. Table of Contents: Introduction / The Heart: Structure, Cardiovascular Diseases, and Regeneration / Cell Sources for Cardiac Tissue Engineering / Biomaterials: Polymers, Scaffolds, and Basic Design Criteria / Biomaterials as Vehicles for Stem Cell Delivery and Retention in the Infarct / Bioengineering of Cardiac Patches, In Vitro / Perfusion Bioreactors and Stimulation Patterns in Cardiac Tissue Engineering / Vascularization of Cardiac Patches / Acellular Biomaterials for Cardiac Repair / Biomaterial-based Controlled Delivery of Bioactive Molecules for Myocardial Regeneration
Book Synopsis Cardiac Tissue Engineering by : Kareen L. K. Coulombe
Download or read book Cardiac Tissue Engineering written by Kareen L. K. Coulombe and published by . This book was released on 2022 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume presents an updated collection of state-of-the-art protocols in cardiac tissue engineering. These protocols demonstrate advancements in cell sourcing, assembly, and use of engineered cardiac tissues, imaging and diagnostics, as well as therapeutic applications. New animal models, biomaterials, and quantitative analyses are described for broad adoption. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cardiac Tissue Engineering: Methods and Protocols, Second Edition serves as an ideal resource for inspiring the advancement of cardiotoxicity assessment, drug discovery, and heart repair and regeneration in order to accelerate heart health improvement around the globe.
Book Synopsis Nanofiber Composites for Biomedical Applications by : Murugan Ramalingam
Download or read book Nanofiber Composites for Biomedical Applications written by Murugan Ramalingam and published by Woodhead Publishing. This book was released on 2017-02-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanofiber Composite Materials for Biomedical Applications presents new developments and recent advances in nanofiber-reinforced composite materials and their use in biomedical applications, including biomaterial developments, drug delivery, tissue engineering, and regenerative medicine. Unlike more conventional titles on composite materials, this book covers the most innovative new developments in nanofiber-based composites, including polymers, ceramics, and metals, with particular emphasis on their preparation and characterization methodology. Selected case studies illustrate new developments in clinical and preclinical use, making the information critical for the development of new medical materials and systems for use in human health care, and for the exploration of new design spaces based on these nanofibers. This book is essential reading for those working in biomedical science and engineering, materials science, nanoscience, biomedical nanotechnology, and biotechnology.
Book Synopsis Cardiac Regeneration and Repair by : Ren-Ke Li
Download or read book Cardiac Regeneration and Repair written by Ren-Ke Li and published by Elsevier. This book was released on 2014-02-17 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac Regeneration and Repair, Volume Two reviews the use of biomaterials, alone or combined with cell therapy, in providing tissue-engineered constructs to repair the injured heart and prevent or reverse heart failure. Part one explores the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Further chapters explore the use of biomaterials to enhance stem cell therapy for restoring ventricular function and generating stem cell-modified intravascular stents. Part two focuses on tissue engineering for cardiac repair, including chapters on decellularized biologic scaffolds, synthetic scaffolds, cell sheet engineering, maturation of functional cardiac tissue patches, vascularized engineered tissues for in vivo and in vitro applications, and clinical considerations for cardiac tissue engineering. Finally, part three explores vascular remodeling, including chapters highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels. Cardiac Regeneration and Repair, Volume Two is complemented by an initial volume covering pathology and therapies. Together, the two volumes of Cardiac Regeneration and Repair provide a comprehensive resource for clinicians, scientists, or academicians fascinated with cardiac regeneration, including those interested in cell therapy, tissue engineering, or biomaterials. Surveys the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Focuses on tissue engineering for cardiac repair including clinical considerations for cardiac tissue engineering Explores vascular remodeling, highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels
Book Synopsis Biomaterials for Cardiac Regeneration by : Erik J. Suuronen
Download or read book Biomaterials for Cardiac Regeneration written by Erik J. Suuronen and published by Springer. This book was released on 2014-11-12 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers readers a comprehensive biomaterials-based approach to achieving clinically successful, functionally integrated vasculogenesis and myogenesis in the heart. Coverage is multidisciplinary, including the role of extracellular matrices in cardiac development, whole-heart tissue engineering, imaging the mechanisms and effects of biomaterial-based cardiac regeneration, and autologous bioengineered heart valves. Bringing current knowledge together into a single volume, this book provides a compendium to students and new researchers in the field and constitutes a platform to allow for future developments and collaborative approaches in biomaterials-based regenerative medicine, even beyond cardiac applications.
Book Synopsis Handbook of Tissue Engineering Scaffolds: Volume Two by : Masoud Mozafari
Download or read book Handbook of Tissue Engineering Scaffolds: Volume Two written by Masoud Mozafari and published by Woodhead Publishing. This book was released on 2019-06-15 with total page 874 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Tissue Engineering Scaffolds: Volume Two provides a comprehensive and authoritative review on recent advancements in the application and use of composite scaffolds in tissue engineering. Chapters focus on specific tissue/organ (mostly on the structure and anatomy), the materials used for treatment, natural composite scaffolds, synthetic composite scaffolds, fabrication techniques, innovative materials and approaches for scaffolds preparation, host response to the scaffolds, challenges and future perspectives, and more. Bringing all the information together in one major reference, the authors systematically review and summarize recent research findings, thus providing an in-depth understanding of scaffold use in different body systems. Dedicated to the specialist topic of composite scaffolds, featuring all human body systems Covers basic fundamentals and advanced clinical applications Includes up-to-date information on preparation methodology and characterization techniques Highlights clinical data and case studies
Book Synopsis Advanced Technologies in Cardiovascular Bioengineering by : Jianyi Zhang
Download or read book Advanced Technologies in Cardiovascular Bioengineering written by Jianyi Zhang and published by Springer Nature. This book was released on 2022-02-05 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a systematic overview of the technologies currently being explored and utilized in the fields of cardiovascular tissue engineering and regenerative medicine. Considering the unprecedented rapid progress occurring on multiple technological fronts in cardiac tissue engineering, this important new volume fills a need for an up-to-date, comprehensive text on emerging advanced biological and engineering tools. The book is an important resource for anyone looking to understand the emerging topics that have the potential to substantially influence the future of the field. Coverage includes iPS stem cell technologies, nanotechnologies and nanomedicine, advanced biomanufacturing, 3D culture systems, 3D organoid systems, genetic approaches to cardiovascular tissue engineering, and organ on a chip. This book will be a valuable guide for research scientists, students, and clinical researchers in the fields of cardiovascular biology, medicine, and bioengineering, as well as industry-based practitioners working in biomaterial science, nanomaterials and technology, and rapid prototyping and biomanufacturing (3D bioprinting).
Book Synopsis Tissue Engineering by : Narine Sarvazyan
Download or read book Tissue Engineering written by Narine Sarvazyan and published by Springer Nature. This book was released on 2020-04-02 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue engineering and regenerative medicine is a new, interdisciplinary branch of science that combines knowledge from numerous scientific fields including biology, biochemistry, physics, chemistry, applied engineering, and medicine. It aims to restore damaged parts of the human body by rebuilding them in vitro using individual building blocks of biological tissues such as cells and the extracellular matrix that surrounds them. The authors hope to spark students’ interest in this exciting new field of science as well as give them a basic knowledge of its terminology. This book is based on a hands-on practical course in tissue engineering conducted by the Fulbright US Scholar recipient, Dr. Narine Sarvazyan (George Washington University, Washington USA). It provides an overview of the core topics of the tissue engineering field, including stem cell differentiation, the role of extracellular matrix and attachment proteins, scaffolds, and culturing of engineered tissues. Each chapter is accompanied by hands-on demonstrations and self-check questions. The text is easily readable for students of all backgrounds and the described protocols can be conducted using common lab equipment. This textbook is also useful for developing undergraduate and graduate courses that teach basic methods and approaches in this promising and rapidly developing field.
Book Synopsis Tissue Engineering for Artificial Organs, 2 Volume Set by : Anwarul Hasan
Download or read book Tissue Engineering for Artificial Organs, 2 Volume Set written by Anwarul Hasan and published by John Wiley & Sons. This book was released on 2017-06-19 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.
Book Synopsis Principles of Tissue Engineering by : Robert Lanza
Download or read book Principles of Tissue Engineering written by Robert Lanza and published by Elsevier. This book was released on 2000-05-16 with total page 995 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field. Key Features * Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves * Essential to anyone working in the field * Educates and directs both the novice and advanced researcher * Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves * Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell * Considered the definitive reference in the field * List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others
Book Synopsis Regenerating the Heart by : Ira S. Cohen
Download or read book Regenerating the Heart written by Ira S. Cohen and published by Springer Science & Business Media. This book was released on 2011-03-23 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical research made huge strides in treating heart disease in the 20th century, from drug-eluding stents to automatic internal defibrillators. Public awareness of the dangers of heart disease has never been more pervasive. Now, though, ten years into a new millennium, scientists are gearing up for the next great challenges in tackling this pervasive condition. Cell therapy is going to be a key weapon in the fight against heart disease. It has the potential to address many cardiovascular conditions. From heart failure to atrioventricular nodal dysfunction, the young but promising field of cell therapy is set to play a significant role in developing the cures that the upcoming decades of hard work will yield. Regenerating the Heart: Stem Cells and the Cardiovascular System organizes the field into a digestible body of knowledge. Its four sections cover mechanical regeneration, electrical regeneration, cardiac tissues and in vivo stem cell therapies. An array of talented researchers share the fruits of their labors, with chapters covering such crucial issues as the cardiogenic potential of varying stem cell types, the ways in which they might be used to tackle arrhythmias, their possible application to biological replacements for cardiac tissues such as valves, and the varying approaches used in the in vivo evaluation of stem cell therapies, including methods of delivering stem cells to the myocardium. This comprehensive survey of an area of research with such exciting potential is an invaluable resource both for veteran stem cell researchers who need to monitor fresh developments, and for newly minted investigators seeking inspirational examples.
