Carbohydrate Silica Nanoparticles For Sirna Delivery

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Handbook of Nanomaterials for Cancer Theranostics

Author : Joao Conde
Publisher : Elsevier
ISBN 13 : 0128133406
Total Pages : 608 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Handbook of Nanomaterials for Cancer Theranostics by : Joao Conde

Download or read book Handbook of Nanomaterials for Cancer Theranostics written by Joao Conde and published by Elsevier. This book was released on 2018-06-27 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. - Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics - Explores the regulatory hurdles facing theranostic nanomedicine - Discusses how the use of nanomaterials can help create more effective cancer treatments

Therapeutic Oligonucleotides

Author : Jens Kurreck
Publisher : Royal Society of Chemistry
ISBN 13 : 0854041168
Total Pages : 362 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Therapeutic Oligonucleotides by : Jens Kurreck

Download or read book Therapeutic Oligonucleotides written by Jens Kurreck and published by Royal Society of Chemistry. This book was released on 2008 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a compelling overall update on current status of RNA interference

Nanostructured Polymer Composites for Biomedical Applications

Author : Sarat Kumar Swain
Publisher : Elsevier
ISBN 13 : 0128168927
Total Pages : 553 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nanostructured Polymer Composites for Biomedical Applications by : Sarat Kumar Swain

Download or read book Nanostructured Polymer Composites for Biomedical Applications written by Sarat Kumar Swain and published by Elsevier. This book was released on 2019-06-15 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructured Polymer Composites for Biomedical Applications addresses the challenges researchers face regarding the creation of nanostructured polymer composites that not only have superior performance and mechanical properties, but also have acceptable biological function. This book discusses current efforts to meet this challenge by discussing the multidisciplinary nature of nanostructured polymer composite biomaterials from various fields, including materials science, polymer science, biomedical engineering and biomedicine. This compilation of existing knowledge will lead to the generation of new terminology and definitions across individual disciplines. As such, this book will help researchers and engineers develop new products and devices for use in effective medical treatment. - Summarizes the most recent strategies to develop nanostructured polymer composite biomaterials for biomedicine - Outlines the major preparation and characterization techniques for a range of polymer nanocomposites used in biomedicine - Explores the design of new types of nanostructured polymer composites for applications in drug delivery, tissue engineering, gene therapy and bone replacement

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance

Author : Muthupandian Saravanan
Publisher : Elsevier
ISBN 13 : 0323998100
Total Pages : 790 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance by : Muthupandian Saravanan

Download or read book Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance written by Muthupandian Saravanan and published by Elsevier. This book was released on 2022-06-22 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance focuses on recent and emerging trends surrounding nanomaterials and nano-drug delivery approaches to combat antimicrobial resistance. The relationship between nanomaterials and antimicrobial activity needs to be deeply explored to meet the challenges of combating antimicrobial resistance. The content of this book is divided into three main topic areas, including (i) how to overcome the existing traditional approaches to combat antimicrobial resistance, (ii) applying multiple drug delivery mechanisms to target multi-drug resistant microbes, and (iii) how nanomaterials can be used as drug carriers. This is an important reference source for those looking to understand how nanotechnology plays an important role in combatting disease and infection. As antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi, this is a timely resource. - Outlines how to overcome existing traditional approaches to combatting antimicrobial resistance - Explains how to apply multiple drug delivery mechanisms (MDR) to the target area in order to better combat antimicrobial resistance - Shows how nanomaterials are used as drug carriers in this context

Advanced Drug Delivery Systems in the Management of Cancer

Author : Kamal Dua
Publisher : Elsevier
ISBN 13 : 0323900798
Total Pages : 574 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Advanced Drug Delivery Systems in the Management of Cancer by : Kamal Dua

Download or read book Advanced Drug Delivery Systems in the Management of Cancer written by Kamal Dua and published by Elsevier. This book was released on 2021-06-24 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. - Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer - Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers - Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems

Mesoporous Silica Nanoparticles

Author : Sachin Namdeo Kothawade
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3111338495
Total Pages : 410 pages
Book Rating : 4.1/5 (113 download)

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Book Synopsis Mesoporous Silica Nanoparticles by : Sachin Namdeo Kothawade

Download or read book Mesoporous Silica Nanoparticles written by Sachin Namdeo Kothawade and published by Walter de Gruyter GmbH & Co KG. This book was released on 2024-11-18 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesoporous silica comprehensively covers the importance and applications of mesoporous silica nanoparticles in the field of nanoscience and nanotechnology. The book delves into the synthesis and characterization of mesoporous silica nanoparticles, discussing various synthesis methods and characterization techniques employed in their production. It explores the properties and structure of mesoporous silica nanoparticles, including their porosity, surface area, structural features, and tunability. It discusses mechanical, thermal, and optical properties. The applications of mesoporous silica nanoparticles in drug delivery are covered in detail, focusing on controlled release systems, targeted drug delivery, and theranostic applications.The catalytic applications of mesoporous silica nanoparticles are examined, including the use of these nanoparticles as supported catalysts in catalytic reactions, with discussions on reaction mechanisms. The book also explores the sensing and biosensing applications of mesoporous silica nanoparticles, including optical and electrochemical sensing, bioanalytical applications, and detection of biomolecules and environmental pollutants. Surface functionalization techniques for mesoporous silica nanoparticles are discussed, highlighting the importance of tailoring their properties for specific applications. Biocompatibility and toxicity considerations are addressed, providing insights into the assessment of biocompatibility, toxicity evaluation, mitigation strategies, and regulatory considerations. The future directions and emerging trends in mesoporous silica nanoparticle research are explored, along with interdisciplinary approaches, challenges, and opportunities in the field. The book concludes by summarizing the key findings and discussing the overall significance of mesoporous silica nanoparticles in nanoscience and nanotechnology. The references section provides a comprehensive list of sources used throughout the book for further exploration. The book serves as an essential resource for researchers, professionals, and students interested in understanding the synthesis, characterization, properties, and diverse applications of mesoporous silica nanoparticles in the realm of nanoscience and nanotechnology.

Applications of Targeted Nano Drugs and Delivery Systems

Author : Shyam Mohapatra
Publisher : Elsevier
ISBN 13 : 0128140305
Total Pages : 684 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Applications of Targeted Nano Drugs and Delivery Systems by : Shyam Mohapatra

Download or read book Applications of Targeted Nano Drugs and Delivery Systems written by Shyam Mohapatra and published by Elsevier. This book was released on 2018-10-05 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Targeted Nano-Drugs and Delivery Systems: Nanoscience and Nanotechnology in Drug Delivery explores the applications of Nano-drugs and their delivery systems, investigating the role they can play in key body systems and major diseases. The book explores how nanotechnology can be deployed in developing new drug delivery systems and how they enable pharmaceutical companies to reformulate existing drugs on the market, thereby extending the lifetime of products and enhancing performance by increasing effectiveness, safety and patient adherence, and ultimately reducing healthcare cost. Reflecting the interdisciplinary nature of the subject matter, this book includes contributions by experts from different fields. Readers will find a reference and practical source of guidance for researchers, students and scientists working in the fields of nanotechnology, materials science, and technology and biomedical science. - Enables readers from different fields to access recent research and protocols across traditional boundaries - Focuses on protocols and techniques, as well as the knowledge base of the field, thus enabling those in R&D to learn about, and successfully deploy, cutting-edge techniques - Explores the applications of Nano-drugs and their delivery systems, investigating the role they can play in key body systems and major disease types

Nanopharmaceuticals: Principles and Applications Vol. 3

Author : Vinod Kumar Yata
Publisher : Springer Nature
ISBN 13 : 3030471209
Total Pages : 352 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Nanopharmaceuticals: Principles and Applications Vol. 3 by : Vinod Kumar Yata

Download or read book Nanopharmaceuticals: Principles and Applications Vol. 3 written by Vinod Kumar Yata and published by Springer Nature. This book was released on 2020-08-19 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the third volume on this subject and focuses on the recent advances of nanopharmaceuticals in cancer, dental, dermal and drug delivery applications and presents their safety, toxicity and therapeutic efficacy. The book also includes the transport phenomenon of nanomaterials and important pathways for drug delivery applications. It goes on to explain the toxicity of nanoparticles to different physiological systems and methods used to assess this for different organ systems using examples of in vivo systems.

Bio-Nanomedicine for Cancer Therapy

Author : Flavia Fontana
Publisher : Springer Nature
ISBN 13 : 3030581748
Total Pages : 358 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Bio-Nanomedicine for Cancer Therapy by : Flavia Fontana

Download or read book Bio-Nanomedicine for Cancer Therapy written by Flavia Fontana and published by Springer Nature. This book was released on 2021-02-04 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book covers the latest developments in biologically-inspired and derived nanomedicine for cancer therapy. The purpose of the book is to illustrate the significance of naturally-mimicking systems for enhancing the dose delivered to the tumor, to improve stability, and prolong the circulation time. Moreover, readers are presented with advanced materials such as adjuvants for immunostimulation in cancer vaccines. The book also provides a comprehensive overview of the current status of academic research. This is an ideal book for students, researchers, and professors working in nanotechnology, cancer, targeted drug delivery, controlled drug release, materials science, and biomaterials as well as companies developing cancer immunotherapy.

Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery

Author : Mahdi Karimi
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1681742586
Total Pages : 98 pages
Book Rating : 4.6/5 (817 download)

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Book Synopsis Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery by : Mahdi Karimi

Download or read book Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery written by Mahdi Karimi and published by Morgan & Claypool Publishers. This book was released on 2015-12-01 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo. This can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to internal stimuli that are intrinsic to the target site. These stimuli are specific to the cell type, tissue or organ type, or to the disease state (cancer, infection, inflammation etc). pH-responsive nanostructures can be used for cargo release in acidic endosomal compartments, in the lower pH of tumors, and for specific oral delivery either to the stomach or intestine. Nanocarriers can be designed to be substrates of a wide-range of enzymes that are over-expressed at disease sites. Oxidation and reduction reactions can be taken advantage of in smart nanocarriers by judicious molecular design. Likewise, nanocarriers can be designed to respond to a range of specific biomolecules that may occur at the target site. In this volume we also cover dual and multi-responsive systems that combine stimuli that could be either internal or external.

Polysaccharide based Nano-Biocarrier in Drug Delivery

Author : Tapan Kumar Giri
Publisher : CRC Press
ISBN 13 : 0429830661
Total Pages : 371 pages
Book Rating : 4.4/5 (298 download)

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Book Synopsis Polysaccharide based Nano-Biocarrier in Drug Delivery by : Tapan Kumar Giri

Download or read book Polysaccharide based Nano-Biocarrier in Drug Delivery written by Tapan Kumar Giri and published by CRC Press. This book was released on 2018-09-03 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses various fundamental aspects of polysaccharide based nano-biocarrier drug delivery systems and its application in the delivery of small molecules, proteins, peptides, oligonucleotides and genes. It also discusses advances in drug delivery systems in treatment of cancer, cardiovascular, pulmonary, and infectious diseases.

Silk-based Drug Delivery Systems

Author : Elia Bari
Publisher :
ISBN 13 : 9781839162664
Total Pages : 0 pages
Book Rating : 4.1/5 (626 download)

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Book Synopsis Silk-based Drug Delivery Systems by : Elia Bari

Download or read book Silk-based Drug Delivery Systems written by Elia Bari and published by . This book was released on 2020-10-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.

Nanoformulations for Sustainable Agriculture and Environmental Risk Mitigation

Author : Zeba Khan
Publisher : CABI
ISBN 13 : 1800623070
Total Pages : 232 pages
Book Rating : 4.8/5 (6 download)

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Book Synopsis Nanoformulations for Sustainable Agriculture and Environmental Risk Mitigation by : Zeba Khan

Download or read book Nanoformulations for Sustainable Agriculture and Environmental Risk Mitigation written by Zeba Khan and published by CABI. This book was released on 2023-07-31 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology research and its application in agriculture has become a major focus in recent years. Nanoformulations offer the possibility to develop more efficient and less damaging agrochemicals in the environment. Smart delivery systems for nanosensors, molecules that can help to detect biotic or abiotic stresses before they can affect production, are being developed and applied. Nanotechnology also provides new techniques for genetic manipulation and plant breeding. The use of nanoformulations in agriculture is increasingly being used to enhance food values, reduce agricultural inputs, improve nutrient contents and create a longer shelf life for many products. Nanotechnology is also being applied to many aspects of food security, disease treatment, new tools for pathogen detection, effective delivery systems and packaging materials. All of these applications are supposed to assist in addressing the needs of a growing population, and help in mitigating the effects of climate change and other ecological disturbances. This book highlights new applications of these nanoforms in the field of agricultural science, written by an international team of experts from across this broad discipline. It is essential reading for graduate students, researchers and practitioners involved in the application of nanotechnology in agriculture.

Chitin and Chitosan

Author : Lambertus A. M. van den Broek
Publisher : John Wiley & Sons
ISBN 13 : 1119450438
Total Pages : 534 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Chitin and Chitosan by : Lambertus A. M. van den Broek

Download or read book Chitin and Chitosan written by Lambertus A. M. van den Broek and published by John Wiley & Sons. This book was released on 2020-01-21 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a comprehensive guide to the isolation, properties and applications of chitin and chitosan Chitin and Chitosan: Properties and Applications presents a comprehensive review of the isolation, properties and applications of chitin and chitosan. These promising biomaterials have the potential to be broadly applied and there is a growing market for these biopolymers in areas such as medical and pharmaceutical, packaging, agricultural, textile, cosmetics, nanoparticles and more. The authors – noted experts in the field – explore the isolation, characterization and the physical and chemical properties of chitin and chitosan. They also examine their properties such as hydrogels, immunomodulation and biotechnology, antimicrobial activity and chemical enzymatic modifications. The book offers an analysis of the myriad medical and pharmaceutical applications as well as a review of applications in other areas. In addition, the authors discuss regulations, markets and perspectives for the use of chitin and chitosan. This important book: Offers a thorough review of the isolation, properties and applications of chitin and chitosan. Contains information on the wide-ranging applications and growing market demand for chitin and chitosan Includes a discussion of current regulations and the outlook for the future Written for Researchers in academia and industry who are working in the fields of chitin and chitosan, Chitin and Chitosan: Properties and Applications offers a review of these promising biomaterials that have great potential due to their material properties and biological functionalities.

Porous Silicon for Biomedical Applications

Author : Hélder A. Santos
Publisher : Woodhead Publishing
ISBN 13 : 0128225246
Total Pages : 646 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Porous Silicon for Biomedical Applications by : Hélder A. Santos

Download or read book Porous Silicon for Biomedical Applications written by Hélder A. Santos and published by Woodhead Publishing. This book was released on 2021-10-23 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Porous Silicon for Biomedical Applications, Second Edition, provides an updated guide to the diverse range of biomedical applications of porous silicon, from biosensing and imaging to tissue engineering and cancer therapy. Across biomedical disciplines, there is an ongoing search for biomaterials that are biocompatible, modifiable, structurally sound, and versatile. Porous silicon possesses a range of properties that make it ideal for a variety of biomedical applications, such as controllable geometry, tunable nanoporous structure, large pore volume/high specific surface area, and versatile surface chemistry. This book provides a fully updated and detailed overview of the range of biomedical applications for porous silicon. Part One offers the reader a helpful insight into the fundamentals and beneficial properties of porous silicon, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein modification, and biocompatibility. The book then builds on the systematic detailing of each biomedical application using porous silicon, from bioimaging and sensing to drug delivery and tissue engineering. This new edition also includes new chapters on in-vivo assessment of porous silicon, photodynamic and photothermal therapy, micro- and nanoneedles, Raman imaging, cancer immunotherapy, and more. With its acclaimed editor and international team of expert contributors, Porous Silicon for Biomedical Applications, Second Edition, is a technical resource and indispensable guide for all those involved in the research, development, and application of porous silicon and other biomaterials, while providing a comprehensive introduction for students and academics interested in this field. - Reviews the fundamental aspects of porous silicon, including the fabrication and unique properties of this useful material. - Discusses a broad selection of biomedical applications, offering a detailed insight into the benefits of porous silicon in both research and clinical settings. - Includes fully updated content from the previous edition, as well as brand new chapters, covering topics such as porous silicon micro- and nanoneedles, and cancer immunotherapy.

Porous Silicon for Biomedical Applications

Author : Hélder A. Santos
Publisher : Elsevier
ISBN 13 : 0128216778
Total Pages : 644 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Porous Silicon for Biomedical Applications by : Hélder A. Santos

Download or read book Porous Silicon for Biomedical Applications written by Hélder A. Santos and published by Elsevier. This book was released on 2021-10-27 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Porous Silicon for Biomedical Applications, Second Edition, provides an updated guide to the diverse range of biomedical applications of porous silicon, from biosensing and imaging to tissue engineering and cancer therapy. Across biomedical disciplines, there is an ongoing search for biomaterials that are biocompatible, modifiable, structurally sound, and versatile. Porous silicon possesses a range of properties that make it ideal for a variety of biomedical applications, such as controllable geometry, tunable nanoporous structure, large pore volume/high specific surface area, and versatile surface chemistry. This book provides a fully updated and detailed overview of the range of biomedical applications for porous silicon. Part One offers the reader a helpful insight into the fundamentals and beneficial properties of porous silicon, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein modification, and biocompatibility. The book then builds on the systematic detailing of each biomedical application using porous silicon, from bioimaging and sensing to drug delivery and tissue engineering. This new edition also includes new chapters on in-vivo assessment of porous silicon, photodynamic and photothermal therapy, micro- and nanoneedles, Raman imaging, cancer immunotherapy, and more. With its acclaimed editor and international team of expert contributors, Porous Silicon for Biomedical Applications, Second Edition, is a technical resource and indispensable guide for all those involved in the research, development, and application of porous silicon and other biomaterials, while providing a comprehensive introduction for students and academics interested in this field. Reviews the fundamental aspects of porous silicon, including the fabrication and unique properties of this useful material. Discusses a broad selection of biomedical applications, offering a detailed insight into the benefits of porous silicon in both research and clinical settings. Includes fully updated content from the previous edition, as well as brand new chapters, covering topics such as porous silicon micro- and nanoneedles, and cancer immunotherapy.

CPP, Cell-Penetrating Peptides

Author : Ülo Langel
Publisher : Springer Nature
ISBN 13 : 3031387317
Total Pages : 564 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis CPP, Cell-Penetrating Peptides by : Ülo Langel

Download or read book CPP, Cell-Penetrating Peptides written by Ülo Langel and published by Springer Nature. This book was released on 2023-10-18 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, a summary and update of the most important areas of cell-penetrating peptides (CPP) research are presented, while raising relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo, is discussed. Therapeutic potential of CPPs and commercial developments are discussed. The present, second edition of this book is the updated and expanded version of the first edition, published in 2019. The development of the field of cell-penetrating peptides in these five years has been obvious and exciting. This second edition of the book has been partly reorganized and comprehensively expanded with the exciting research in 2019-2023. Around 2500 novel scientific articles have become available, most of them are reviewed in the second edition. Additional rapidly growing areas of high impact presented in this second edition are therapeutic developments (Chapter 16) and delivery of oligonucleotides and proteins/peptides (Chapters 5 and 6) including novel reports on genome editing with CPP assistance. Also, several additional examples are available now on clinical trials using CPPs (Chapter 15). The book is written for researchers and students in the field.