Cancer Metastasis And Cancer Stem Cell Niche

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Cancer Metastasis and Cancer Stem Cell/Niche

Author : Takanori Kawaguchi
Publisher : Bentham Science Publishers
ISBN 13 : 1681083477
Total Pages : 157 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Cancer Metastasis and Cancer Stem Cell/Niche by : Takanori Kawaguchi

Download or read book Cancer Metastasis and Cancer Stem Cell/Niche written by Takanori Kawaguchi and published by Bentham Science Publishers. This book was released on 2016-11-04 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: A malignant tumor is an actively growing tissue, composed of cells derived from a single cell line that has undergone irreversible differentiation. These cells are invasive and also metastasize in the body, resulting in malignant cancer. Recent research suggests that a malignant tumor originates from cancer stem cells (CSC) accompanied with physiological niches. Cancer Metastasis and Stem Cell/Niche explains the invasiveness and metastasis of cancer cells I the light of information gained from the CSC / niche theory. Five chapters present a review on the fundamental relationships between CSCs, their niche and metastasis, the regulation of cell surface glycan expression in CSCs, tumor endothelial cells and metastasis, toll-like receptor 4 (TLR4)-mediated premetastatic microenvironment, and in surgical cancer metastasis. This monograph is intended as a primary reference on CSC research for physiologists, clinical oncologists, stem cell researchers and molecular biologists.

The Cancer Stem Cell Niche

Author : Susie Nilsson
Publisher : Academic Press
ISBN 13 : 0323853269
Total Pages : 248 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis The Cancer Stem Cell Niche by : Susie Nilsson

Download or read book The Cancer Stem Cell Niche written by Susie Nilsson and published by Academic Press. This book was released on 2021-01-23 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cancer Stem Cell Niche, Volume Five in the Advances in Stem Cells and their Niches series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Acute lymphoblastic leukemia and the bone marrow microenvironment, Stem cell niches in bone and their roles in cancer metastasis, The role of vasculature in cancer stem cell niches, The lung cancer stem cell niche, The prostate cancer stem cell niche: Genetic drivers and therapeutic approaches, Impact of prostate cancer stem cell niches on prostate cancer tumorigenesis and progression, The testicular cancer stem cell niche. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Stem Cells and their Niches series Includes the latest information on the Cancer Stem Cell Niche

The Cancer Stem Cell Niche

Author : Susie Nilsson
Publisher : Academic Press
ISBN 13 : 0323853250
Total Pages : 246 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis The Cancer Stem Cell Niche by : Susie Nilsson

Download or read book The Cancer Stem Cell Niche written by Susie Nilsson and published by Academic Press. This book was released on 2021-02-09 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cancer Stem Cell Niche, Volume Five in the Advances in Stem Cells and their Niches series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Acute lymphoblastic leukemia and the bone marrow microenvironment, Stem cell niches in bone and their roles in cancer metastasis, The role of vasculature in cancer stem cell niches, The lung cancer stem cell niche, The prostate cancer stem cell niche: Genetic drivers and therapeutic approaches, Impact of prostate cancer stem cell niches on prostate cancer tumorigenesis and progression, The testicular cancer stem cell niche. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Stem Cells and their Niches series Includes the latest information on the Cancer Stem Cell Niche

Cancer Stem Cells

Author :
Publisher : Academic Press
ISBN 13 : 0128149957
Total Pages : 267 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Cancer Stem Cells by :

Download or read book Cancer Stem Cells written by and published by Academic Press. This book was released on 2019-01-26 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Stem Cells, Volume 141 in the Advances in Cancer Research series, presents the latest release in this ongoing, well-regarded serial that provides invaluable information on the exciting and fast-moving field of cancer research. Topics covered in this new release include SIX-EYA-DACH network control of cancer stem cell properties, Dormancy and the cancer cell niche, Clonal hematopoiesis: A hematopoietic stem cell disorder of aging, Stringent assays to study human breast cancer stem cells, Regulation of breast cancer stem cell specification and maintenance by hypoxia-inducible factors, Cancer stem cells in breast and prostate: fact or fiction, and much more. Provides information on cancer research Offers outstanding and original reviews on a range of cancer research topics, with this release focusing on cancer stem cells Serves as an indispensable reference for researchers and students alike

Cancer Stem Cells

Author : Stanley Shostak
Publisher : BoD – Books on Demand
ISBN 13 : 9533072253
Total Pages : 476 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Cancer Stem Cells by : Stanley Shostak

Download or read book Cancer Stem Cells written by Stanley Shostak and published by BoD – Books on Demand. This book was released on 2011-03-22 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Stem Cells Theories and Practice does not 'boldly go where no one has gone before!' Rather, Cancer Stem Cells Theories and Practice boldly goes where the cutting edge of research theory meets the concrete challenges of clinical practice. Cancer Stem Cells Theories and Practice is firmly grounded in the latest results on cancer stem cells (CSCs) from world-class cancer research laboratories, but its twenty-two chapters also tease apart cancer's vulnerabilities and identify opportunities for early detection, targeted therapy, and reducing remission and resistance.

Cancer Stem Cell Niche: The Role of Mesenchymal Stem Cells in Tumor Microenvironment 189

Author : Kanya Honoki
Publisher :
ISBN 13 : 9789533075808
Total Pages : pages
Book Rating : 4.0/5 (758 download)

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Book Synopsis Cancer Stem Cell Niche: The Role of Mesenchymal Stem Cells in Tumor Microenvironment 189 by : Kanya Honoki

Download or read book Cancer Stem Cell Niche: The Role of Mesenchymal Stem Cells in Tumor Microenvironment 189 written by Kanya Honoki and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Role of Cancer Stem Cells in Cancer Biology and Therapy

Author : Thomas Dittmar
Publisher : CRC Press
ISBN 13 : 1466577363
Total Pages : 330 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Role of Cancer Stem Cells in Cancer Biology and Therapy by : Thomas Dittmar

Download or read book Role of Cancer Stem Cells in Cancer Biology and Therapy written by Thomas Dittmar and published by CRC Press. This book was released on 2016-04-19 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology and how this knowledge could be used for novel anticancer therapies. It provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias. It then reviews the role of CSCs in metastasis formation and initiat

Cancer Stem Cells

Author : Stanley Shostak
Publisher : IntechOpen
ISBN 13 : 9789533075808
Total Pages : 632 pages
Book Rating : 4.0/5 (758 download)

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Book Synopsis Cancer Stem Cells by : Stanley Shostak

Download or read book Cancer Stem Cells written by Stanley Shostak and published by IntechOpen. This book was released on 2011-08-01 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last thirty years, the foremost inspiration for research on metastasis, cancer recurrence, and increased resistance to chemo- and radiotherapy has been the notion of cancer stem cells.The twenty-eight chapters assembled in Cancer Stem Cells - The Cutting Edge summarize the work of cancer researchers and oncologists at leading universities and hospitals around the world on every aspect of cancer stem cells, from theory and models to specific applications (glioma), from laboratory research on signal pathways to clinical trials of bio-therapies using a host of devices, from solutions to laboratory problems to speculation on cancers' stem cells' evolution. Cancer stem cells may or may not be a subset of slowly dividing cancer cells that both disseminate cancers and defy oncotoxic drugs and radiation directed at rapidly dividing bulk cancer cells, but research on cancer stem cells has paid dividends for cancer prevention, detection, targeted treatment, and improved prognosis.

Cancer Stem Cells in Solid Tumors

Author : Alison L. Allan
Publisher : Springer Science & Business Media
ISBN 13 : 1617792462
Total Pages : 479 pages
Book Rating : 4.6/5 (177 download)

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Book Synopsis Cancer Stem Cells in Solid Tumors by : Alison L. Allan

Download or read book Cancer Stem Cells in Solid Tumors written by Alison L. Allan and published by Springer Science & Business Media. This book was released on 2011-08-12 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: The “cancer stem cell” hypothesis postulates that cancer arises from a subpopulation of tumor-initiating cells or cancer stem cells (CSCs). While the idea of cancer stem cells has been around for more than a hundred years, evidence from the fields of hematology and cancer biology has now demonstrated the critical role of stem cells in hematological malignancies and suggested that these same mechanisms are also central to the initiation, progression, and treatment of solid cancers. Clinical and experimental studies have shown that CSCs exhibit many classical properties of normal stem cells, including a high self-renewal capacity and the ability to generate heterogeneous lineages; the requirement for a specific “niche”/microenvironment to grow; and an increased capacity for self-protection against harsh environments, toxins, and drugs. Cancer Stem Cells in Solid Tumors represents a detailed overview of cancer stem cells and their role in solid cancers. Comprised of 24 chapters, this volume will provide readers with a comprehensive understanding of this important and evolving field. Topics covered include: Introduction of the CSC hypothesis Historical perspectives and the contributing lessons from leukemia Current knowledge regarding the identification and role of CSCs in various forms of solid cancer including breast, brain, colorectal, pancreatic, prostate, melanoma, lung, ovarian, hepatocellular, and head and neck cancer Molecular pathways involved in driving CSC function, with a particular focus on the novel convergence of embryonic and tumorigenic signaling pathways In vitro and in vivo assays, model systems, and imaging modalities for studying CSCs The clinical importance of CSCs for cancer management and treatment, including important implications for prognosis, prediction, and treatment resistance Consideration of the controversy surrounding the CSC hypothesis and important unanswered questions in this field This collective work was written by a group of prominent international experts in cancer biology, oncology, and/or stem cell biology. It will serve as a valuable resource for established researchers, professors, health care professionals, and students in the medical and scientific community who are investigating stem cells and/or oncology.

Cancer Stem Cells

Author : Sharmila A. Bapat
Publisher : John Wiley & Sons
ISBN 13 : 0470391561
Total Pages : 274 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Cancer Stem Cells by : Sharmila A. Bapat

Download or read book Cancer Stem Cells written by Sharmila A. Bapat and published by John Wiley & Sons. This book was released on 2008-10-03 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because the concept and discoveries of cancer stem cells are relatively new, scientists and researchers need an introduction to this dynamic area. Cancer Stem Cells presents a consolidated account of the research done to date and recent progresses in the studies of cancer stem cells. Such a presentation facilitates a better understanding of and draws attention to stem cell and cancer biology - two fields that enhance, move, and evolve into each other continuously. It provides an informative study in designing approaches to apply stem cell principles to cancer biology while offering an overview of the challenges in developing combination stem and cancer biology targets for therapeutics. This book serves as a primer for new researchers in the field of cancer biology.

Stem Cells and Cancer

Author : Lopa Mishra
Publisher : IOS Press
ISBN 13 : 9781586038021
Total Pages : 112 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Stem Cells and Cancer by : Lopa Mishra

Download or read book Stem Cells and Cancer written by Lopa Mishra and published by IOS Press. This book was released on 2007 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the role of cancer stem cells and progenitor cells in the progression to cancer. This volume refers to the role of stem cells in well-characterized diseases such as prostate and hepatocellular cancer, melanoma, chronic myeloid leukaemia and stem cell/cancer stem cell properties.

Cancer Stem Cells

Author : Huiping Liu
Publisher : Elsevier
ISBN 13 : 0128039345
Total Pages : 544 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Cancer Stem Cells by : Huiping Liu

Download or read book Cancer Stem Cells written by Huiping Liu and published by Elsevier. This book was released on 2016-08-16 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Stem Cells: Targeting the Roots of Cancer, Seeds of Metastasis, and Sources of Therapy Resistance introduces the basic concepts and advanced understanding of cancer stem cells, covering general overviews, organ-specific identifications, and their characteristic mechanisms. The book also explores innovative therapeutic strategies in preclinical and clinical trials to target cancer stem cells, remove the roots of cancer, eliminate the seeds of metastasis, overcome the resistance of therapies, and contribute to the eradication of cancer. The book includes contributions from leading, worldwide experts in the field, helping readers embrace new hope in their quest to eradicate cancer with emerging clinical trials on treating cancer stem cells in combination with other therapies. Provides an authoritative and complete overview of cancer stem cells Includes comprehensive coverage of current therapeutic strategies targeting cancer stem cells Deepens a reader’s technical expertise in cancer stem cell biology

Origin of Cancers

Author : Shi-Ming Tu
Publisher : Springer Science & Business Media
ISBN 13 : 1441959688
Total Pages : 247 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Origin of Cancers by : Shi-Ming Tu

Download or read book Origin of Cancers written by Shi-Ming Tu and published by Springer Science & Business Media. This book was released on 2010-07-20 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Précis This book is a treatise about the origin of cancers. I would like to convince readers that the basic tenets of the theory of a stem-cell origin of cancers also constitute a unified theory of cancer. Stem-cell origin of normal (and cancer) cells: Vitruvian version Every truth passes through three stages before it is recognized. In the first it is ridiculed, in the second, it is opposed, in the third, it is regarded as self-evident. – Arthur Schopenhauer v vi Preface Every person has a unique story to tell. My story is about cancer. Cancer touches the lives of countless people. Often enough, it leaves indelible tracks. Many lives have been lost; others are forever changed. For those who confront this deadly scourge, there is a sense of urgency, if not of desperation. For those who face im- nent death, life becomes even more precious and carries a special meaning. As an oncologist, I am touched daily by cancer. I feel its inception, evolution, and aft- math. It seems as though we are fighting an incessant war against cancer at the front line in the trenches. This is my story about cancer. Some people are terrific storytellers. Others have incredible tales to tell.

Principles of Stem Cell Biology and Cancer

Author : Tarik Regad
Publisher : John Wiley & Sons
ISBN 13 : 1118670620
Total Pages : 378 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Principles of Stem Cell Biology and Cancer by : Tarik Regad

Download or read book Principles of Stem Cell Biology and Cancer written by Tarik Regad and published by John Wiley & Sons. This book was released on 2015-05-06 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.

Cancer Stem Cells: Basic Concept and Therapeutic Implications

Author : Farhadul Islam
Publisher : Springer Nature
ISBN 13 : 9819931851
Total Pages : 375 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Cancer Stem Cells: Basic Concept and Therapeutic Implications by : Farhadul Islam

Download or read book Cancer Stem Cells: Basic Concept and Therapeutic Implications written by Farhadul Islam and published by Springer Nature. This book was released on 2023-07-26 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews the role of cancer stem cells (CSCs) in cancer initiation, progression, and resistance to anticancer therapies. The initial chapters examine the methods and procedure of the detection, isolation, and characterization of CSCs. It also introduces various epigenetic pathways that contribute to cancer initiation and tumorigenesis, particularly regarding the maintenance and survival of CSCs. It also explores the role of CSCs metabolism and the mechanisms of metabolic plasticity of CSCs in cancer biology. Further, it also presents the implications of CSCs on the origin of tumor heterogeneity and on heterogeneity of the therapeutic response. Towards the end, this book highlights the different immunotherapeutic approaches targeting CSCs with the potential of strongly improving cancer outcomes. This book offers a broad framework to scientists and clinicians into the state-of-the-art knowledge on cancer stem cell biology and highlights their therapeutic implications.

Cancer Stem Cells

Author : Lucie Laplane
Publisher : Harvard University Press
ISBN 13 : 0674088743
Total Pages : 265 pages
Book Rating : 4.6/5 (74 download)

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Book Synopsis Cancer Stem Cells by : Lucie Laplane

Download or read book Cancer Stem Cells written by Lucie Laplane and published by Harvard University Press. This book was released on 2016-06-06 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part IV: The Identity of Stemness and Its Consequences for Cancer Therapies -- Chapter 7. If Stemness Is a Categorical or a Dispositional Property, How Can We Cure Cancers? -- Chapter 8. If Stemness Is a Relational or a Systemic Property, How Can We Cure Cancers? -- Conclusion -- Notes -- References -- Acknowledgments -- Index

Cancer Stem Cells and Signaling Pathways

Author : Surajit Pathak
Publisher : Elsevier
ISBN 13 : 0443132119
Total Pages : 703 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Cancer Stem Cells and Signaling Pathways by : Surajit Pathak

Download or read book Cancer Stem Cells and Signaling Pathways written by Surajit Pathak and published by Elsevier. This book was released on 2023-11-14 with total page 703 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Stem Cells and Signaling Pathways explores the mechanism of cancer stem cell signaling pathways in cancer advancement, serving as an ideal reference guide for investigators with valuable answers to problems associated with anti-cancer treatments and an understanding of the crosstalk among the signaling pathways in CSC regulation. Despite recent advances in tumor therapy and a greater understanding of their biology, tumors continue to be a prevalent and fatal worldwide. According to a novel paradigm in tumor biology, a small percentage of the cells within a tumor known as cancer stem cells (CSCs) are predicted as a crucial population for tumor progression. Presents cancer stem characteristics and their signaling pathways Highlights the use of animal models for cancer research, the use of genetically modified stem cells to deliver antitumor agents, and the significance of stem cell signaling in drug discovery Covers basic and translational research appropriate for scientists and clinicians exploring alternative treatments for various cancers