Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 111953030X
Total Pages : 6057 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set by :

Download or read book Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set written by and published by John Wiley & Sons. This book was released on 2021-04-20 with total page 6057 pages. Available in PDF, EPUB and Kindle. Book excerpt: Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures. Along with the incorporation of practical material on drug hunting, the set features sections on drug discovery, drug development, cardiovascular diseases, metabolic diseases, immunology, cancer, anti-Infectives, and CNS disorders. The text continues the legacy of previous volumes in the series by providing recognized, renowned, authoritative, and comprehensive information in the area of drug discovery and development while adding cutting-edge new material on issues like the use of artificial intelligence in medicinal chemistry. Included: Volume 1: Methods in Drug Discovery, edited by Kent D. Stewart Volume 2: Discovering Lead Molecules, edited by Kent D. Stewart Volume 3: Drug Development, edited by Ramnarayan S. Randad and Michael Myers Volume 4: Cardiovascular, Endocrine, and Metabolic Diseases, edited by Scott D. Edmondson Volume 5: Pulmonary, Bone, Immunology, Vitamins, and Autocoid Therapeutic Agents, edited by Bryan H. Norman Volume 6: Cancer, edited by Barry Gold and Donna M. Huryn Volume 7: Anti-Infectives, edited by Roland E. Dolle Volume 8: CNS Disorders, edited by Richard A. Glennon Perfect for research departments in the pharmaceutical and biotechnology industries, Burger’s Medicinal Chemistry, Drug Discovery and Development can be used by graduate students seeking a one-stop reference for drug development and discovery and deserves its place in the libraries of biomedical research institutes, medical, pharmaceutical, and veterinary schools.

Burger's Medicinal Chemistry and Drug Discovery, 6 Volume Set

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Author :
Publisher : Wiley-Interscience
ISBN 13 : 9780471370321
Total Pages : 5568 pages
Book Rating : 4.3/5 (73 download)

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Book Synopsis Burger's Medicinal Chemistry and Drug Discovery, 6 Volume Set by : Donald J. Abraham

Download or read book Burger's Medicinal Chemistry and Drug Discovery, 6 Volume Set written by Donald J. Abraham and published by Wiley-Interscience. This book was released on 2003-03-07 with total page 5568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new sixth edition of Burger's Medicinal Chemistry and Drug Discovery offers several new and unique features. For the first time, an online version of this major reference work will offer updated content from the print edition and easy access. For the first time, all volumes are structured entirely according to content and published simultaneously to provide broad coverage of medicinal chemistry and drug discovery for new or experienced medicinal chemists, biologists, pharmacologists and molecular biologists. This includes a current and global perspective of drug design, and drug development. With expanded content from 69 chapters to over 100 chapters, this sixth edition of Burger's Medicinal Chemistry and Drug Discovery includes more than 50% new material. An entire section has been dedicated to cancer research. Areas included are those at the foreground of life science including: * Proteomics * Genomics * Bioinformatics * Combinatorial Chemistry * High-Throughput Screening * Blood Substitutes * Allosteric Effectors as Potential Drugs * COX Inhibitors * Statins * High-Throughput Pharmacology * and More. The new sixth edition of Burger's Medicinal Chemistry and Drug Discovery is a Memorial Edition to Professor Alfred Burger who published this major reference work in the first edition as "Medicinal Chemistry" in two volumes in 1951. Dr. Burger's research focused on analgesics, antidepressants and chemotherapeutic agents. He is one of the few academicians to have a drug, designed and synthesized in his laboratories and brought to market. Dr. Burger's contribution to the fields of medicinal chemistry and drug discovery are well renowned and documented. He received the Louis Pasteur Medal of the Pasteur Institute and the American Chemical Society Smissman Award.

Burger's Medicinal Chemistry, Drug Discovery, and Development, Set

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Author :
Publisher : Wiley
ISBN 13 : 9780470278154
Total Pages : 0 pages
Book Rating : 4.2/5 (781 download)

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Book Synopsis Burger's Medicinal Chemistry, Drug Discovery, and Development, Set by : Donald J. Abraham

Download or read book Burger's Medicinal Chemistry, Drug Discovery, and Development, Set written by Donald J. Abraham and published by Wiley. This book was released on 2010-10-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its seventh edition, Burger's Medicinal Chemistry, Drug Discovery and Development provides an established, recognized, authoritative and comprehensive source on medicinal chemistry and drug discovery and development. This flagship reference for medicinal chemists and pharmaceutical professions has been thoroughly updated and expanded across 8 volumes to incorporate the entire process of drug development (preclinical testing, clinical trials, etc.) alongside the traditional strengths in medicinal chemistry and drug discovery.

Burger's Medicinal Chemistry, Drug Discovery and Development

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780470770085
Total Pages : 844 pages
Book Rating : 4.7/5 (7 download)

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Book Synopsis Burger's Medicinal Chemistry, Drug Discovery and Development by : Donald J. Abraham

Download or read book Burger's Medicinal Chemistry, Drug Discovery and Development written by Donald J. Abraham and published by John Wiley & Sons. This book was released on 2010-01-01 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rev. ed. of: Burger's medicinal chemistry and drug discovery. 6th ed. / edited by Donald J. Abraham. c2003.

Burger's Medicinal Chemistry and Drug Discovery, Chemotherapeutic Agents

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Publisher : Wiley-Interscience
ISBN 13 : 9780471370314
Total Pages : 0 pages
Book Rating : 4.3/5 (73 download)

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Book Synopsis Burger's Medicinal Chemistry and Drug Discovery, Chemotherapeutic Agents by : Donald J. Abraham

Download or read book Burger's Medicinal Chemistry and Drug Discovery, Chemotherapeutic Agents written by Donald J. Abraham and published by Wiley-Interscience. This book was released on 2003-03-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is Volume 5: Chemotherapeutic Agents, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Molecular Biology of Cancer, Synthetic Anti-angiogenic Agents and Selective Toxicities. To purchase the entire 6 volume set, please refer to ISBN 0-471-37032-0. For a complete list of articles and contributors as well as FREE sample chapters from this new 6th Edition please visit: www.mrw.interscience.wiley.com/bmcdd

Burger's Medicinal Chemistry

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Author :
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 1382 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Burger's Medicinal Chemistry by : Alfred Burger

Download or read book Burger's Medicinal Chemistry written by Alfred Burger and published by John Wiley & Sons. This book was released on 1981 with total page 1382 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thoroughly revised and expanded edition of a best-selling classic reference on principles and practice of medicinal chemistry and drug discovery. Volume 1 covered principles. Volumes 2 through 5 focus on drugs that target a particular organ or system. Volume 4 features authoritative and comprehensive surveys of cardiovascular drugs and chemotherapeutic agents, as well as information on radiological agents and opthalmic drugs. -- Volume 5 surveys central nervous system (CNS), endocrine, and immune system drugs.

Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development

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Author :
Publisher : Wiley-Interscience
ISBN 13 : 9780471370284
Total Pages : 840 pages
Book Rating : 4.3/5 (72 download)

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Book Synopsis Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development by : Donald J. Abraham

Download or read book Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development written by Donald J. Abraham and published by Wiley-Interscience. This book was released on 2003-01-23 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is Volume 2: Drug Discovery and Drug Development, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Combinational Chemistry and Multiple Parallel Synthesis, High Throughput Pharmacology, and Retrometabolism-Based Drug Design and Targeting. To purchase the entire 6 volume set, please refer to ISBN 0-471-37032-0. For a complete list of articles and contributors as well as FREE sample chapters from this new 6th Edition please visit: www.mrw.interscience.wiley.com/bmcdd

Burger's Medicinal Chemistry and Drug Discovery, Therapeutic Agents

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Author :
Publisher : Wiley-Interscience
ISBN 13 : 9780471575573
Total Pages : 688 pages
Book Rating : 4.5/5 (755 download)

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Book Synopsis Burger's Medicinal Chemistry and Drug Discovery, Therapeutic Agents by : Manfred E. Wolff

Download or read book Burger's Medicinal Chemistry and Drug Discovery, Therapeutic Agents written by Manfred E. Wolff and published by Wiley-Interscience. This book was released on 1996-04-26 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive source of the latest information in drug discovery and medicinal chemistry BURGER'S MEDICINAL CHEMISTRY AND DRUG DISCOVERY, FIFTH EDITION, Volume 2: Therapeutic Agents Renowned for its incisive, systematic examination of the new classes of drugs, Burger's Medicinal Chemistry and Drug Discovery provides professionals with thorough, yet selective access to drug chemistry information in a convenient format. Volume 2 outlines the newest generation of drugs with the potential for controlling cardiovascular, gastrointestinal, and tubercular disease. These include: * Cholinergics and anticholinergics * Gastric proton pump inhibitors * Cardiac drugs and antihypertensive agents * Diuretic and urcosuric agents * Aminoglycoside, macrolide, glycopeptide, and other antibacterial antibiotics * Antimycobacterial and antifungal agents The behavior of each drug class is explored in terms of pathophysiology of the disease state, molecular mechanism of action, pharmacokinetics, toxicity, drug metabolism, and structure activity relationships. Special attention is given to fertile areas of further research. Burger's Medicinal Chemistry and Drug Discovery, Volume 2 is an essential reference for medical professionals and researchers working today. Burger's Medicinal Chemistry, Fifth Edition consists of five volumes: Volume 1: Principles and Practice (0-471-57556-9) 1995 " . . . an essential addition to the libraries of any medicinal chemist . . . an outstanding work . . . highly praised as a fountain of information in drug studies and research."--Journal of Medicinal Chemistry * Volume 2: Therapeutic Agents (0-471-57557-7) 1996 * Volume 3: Therapeutic Agents (0-471-57558-5) 1996 * Volume 4: Therapeutic Agents (0-471-57559-3) 1997 * Volume 5: Therapeutic Agents (0-471-57560-7) 1997

Medicinal Chemistry

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Author :
Publisher : Prentice Hall
ISBN 13 : 9780321710482
Total Pages : 418 pages
Book Rating : 4.7/5 (14 download)

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Book Synopsis Medicinal Chemistry by : Erland Stevens

Download or read book Medicinal Chemistry written by Erland Stevens and published by Prentice Hall. This book was released on 2014 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing applications of chemistry while reinforcing theory – especially in the areas of organic and physical chemistry – this new text prepares readers for career success in the pharmaceutical, medical, and biotech industries. Medicinal Chemistry: The Modern Drug Discovery Process delivers a comprehensive introduction to medicinal chemistry at an appropriate level of detail for a diverse range of readers. By highlighting the concepts and skills related to drug discovery, Stevens deepens readers' understanding of the knowledge and techniques necessary for their careers.

Textbook of Organic Medicinal and Pharmaceutical Chemistry

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 1140 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Textbook of Organic Medicinal and Pharmaceutical Chemistry by : Charles Owens Wilson

Download or read book Textbook of Organic Medicinal and Pharmaceutical Chemistry written by Charles Owens Wilson and published by Lippincott Williams & Wilkins. This book was released on 1977 with total page 1140 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Burger's Medicinal Chemistry and Drug Discovery, Principles and Practice

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Author :
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 1102 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Burger's Medicinal Chemistry and Drug Discovery, Principles and Practice by : Alfred Burger

Download or read book Burger's Medicinal Chemistry and Drug Discovery, Principles and Practice written by Alfred Burger and published by Wiley-Interscience. This book was released on 1995-01-02 with total page 1102 pages. Available in PDF, EPUB and Kindle. Book excerpt: BURGER'S MEDICINAL CHEMISTRY AND DRUG DISCOVERY, FIFTH EDITION, Volume 1: Principles and Practice This new edition of Dr. Alfred Burger's internationally celebrated classic helps researchers acquaint themselves with both traditional and state-of-the-art principles and practices governing new drug research and development. Completely updated and revised to reflect the many monumental changes that have occurred over the past decade and a half in medicinal chemistry and new drug development, this latest edition of Volume 1: Principles and Practice now: * Covers the latest methods of drug discovery, including such "hot" topics as computational chemistry and peptidomimetrics * Has added emphasis on preclinical development issues * Offers the most timely information on a broad range of important regulatory, management, legal, and financial issues * Features in-depth coverage of important factors in the discovery process, including ADME, toxicity and drug allergy, and clinical trials * Updates readers on recent advances in the understanding of the structural biology of drug action * Explores the cutting-edge technologies for drug discovery now in use around the world * Is more than twice the size of its predecessor * Brings together contributions by experts in a wide range of related fields from North America and Europe

Medicinal Chemistry

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Author :
Publisher : Oxford University Press
ISBN 13 : 0190282967
Total Pages : 649 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Medicinal Chemistry by : Thomas Nogrady

Download or read book Medicinal Chemistry written by Thomas Nogrady and published by Oxford University Press. This book was released on 2005-08-11 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.

Burger's Medicinal Chemistry

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Author :
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 520 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Burger's Medicinal Chemistry by : Alfred Burger

Download or read book Burger's Medicinal Chemistry written by Alfred Burger and published by John Wiley & Sons. This book was released on 1980 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Burger's Medicinal Chemistry and Drug Discovery

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Author :
Publisher : Wiley-Interscience
ISBN 13 : 9780471372189
Total Pages : 608 pages
Book Rating : 4.3/5 (721 download)

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Book Synopsis Burger's Medicinal Chemistry and Drug Discovery by : Donald J. Abraham

Download or read book Burger's Medicinal Chemistry and Drug Discovery written by Donald J. Abraham and published by Wiley-Interscience. This book was released on 2008-05-01 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry provides medical researchers with knowledge about chemical structures, chemical reactions, reaction mechanisms, and biochemical mechanisms of therapeutic agents. This comprehensive source of information for medicinal chemists has been thoroughly updated and improved.

Burger's Medicinal Chemistry and Drug Discovery, Academic Version

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Author :
Publisher : Wiley-Interscience
ISBN 13 : 9780471370277
Total Pages : 608 pages
Book Rating : 4.3/5 (72 download)

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Book Synopsis Burger's Medicinal Chemistry and Drug Discovery, Academic Version by : Donald J. Abraham

Download or read book Burger's Medicinal Chemistry and Drug Discovery, Academic Version written by Donald J. Abraham and published by Wiley-Interscience. This book was released on 2008-06 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design

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Author :
Publisher : Springer Nature
ISBN 13 : 9811589364
Total Pages : 334 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design by : Sanjeev Kumar Singh

Download or read book Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design written by Sanjeev Kumar Singh and published by Springer Nature. This book was released on 2021-02-02 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents various computer-aided drug discovery methods for the design and development of ligand and structure-based drug molecules. A wide variety of computational approaches are now being used in various stages of drug discovery and development, as well as in clinical studies. Yet, despite the rapid advances in computer software and hardware, combined with the exponential growth in the available biological information, there are many challenges that still need to be addressed, as this book shows. In turn, it shares valuable insights into receptor-ligand interactions in connection with various biological functions and human diseases. The book discusses a wide range of phylogenetic methods and highlights the applications of Molecular Dynamics Simulation in the drug discovery process. It also explores the application of quantum mechanics in order to provide better accuracy when calculating protein-ligand binding interactions and predicting binding affinities. In closing, the book provides illustrative descriptions of major challenges associated with computer-aided drug discovery for the development of therapeutic drugs. Given its scope, it offers a valuable asset for life sciences researchers, medicinal chemists and bioinformaticians looking for the latest information on computer-aided methodologies for drug development, together with their applications in drug discovery.

Successful Drug Discovery, Volume 4

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Publisher : John Wiley & Sons
ISBN 13 : 352781471X
Total Pages : 317 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Successful Drug Discovery, Volume 4 by : János Fischer

Download or read book Successful Drug Discovery, Volume 4 written by János Fischer and published by John Wiley & Sons. This book was released on 2019-07-20 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides unique insider insight into the current drug development process, and what it takes to achieve success In this fourth volume in the series, inventors and primary developers of drugs that made it to the market continue telling the story of the drugs? discovery and development, and discuss the sometimes twisted route from the first drug candidate molecule to the final marketed one. Beginning with a general section addressing overarching topics for drug discovery, the book offers seven chapters that feature selected case studies describing recently introduced drugs or drug classes. These include small molecule drugs as well as biopharmaceuticals and range across different therapeutic fields. Together, they provide a representative cross-section of the present-day drug development effort. Successful Drug Discovery: Volume 4 covers trends in peptide-based drug discovery and the physicochemical properties of recently approved oral drugs. The section on drug class studies looks at antibody-drug conjugates and the discovery, evolution, and therapeutic potential of dopamine partial agonists. Featured case studies examine the discovery of Etelcalcetide for the treatment of secondary hyper-parathyroidism in patients with chronic kidney disease; the development of Lenvatinib Mesylate; the discovery and development of Venetoclax; and more. -Focuses on recently introduced drugs that have not been featured in any textbooks or general references, including Ocrelizumab, a new generation of anti-CD-20 mAb for the treatment of multiple sclerosis, and Venetoclax, a selective antagonist of BCL-2 -Features personal experiences of successful drug developers from industry and academia -Endorsed and supported by the International Union of Pure and Applied Chemistry (IUPAC) Successful Drug Discovery: Volume 4 provides a fascinating and informative look into the process of drug discovery and would be a great reference for those in the pharmaceutical industry, organic and pharmaceutical chemists, and lecturers in pharmacy.