Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Breast Epithelial Antigens
Download Breast Epithelial Antigens full books in PDF, epub, and Kindle. Read online Breast Epithelial Antigens ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Breast Epithelial Antigens by : R.L. Ceriani
Download or read book Breast Epithelial Antigens written by R.L. Ceriani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: The wealth of research results in the area of breast cancer diagnosis and therapy with monoclonal antibodies presented in previous workshops is now complemented with a new rendition of the proceedings of the 4th Workshop on Monoclonal Antibodies and Breast Cancer. held in San Francisco on November 5-6. 1990. Basic science findings reported in previous workshops have now percolated to the clinical level and have become immunoassays and imaging and therapy reagents. as the program shows us. Thus. the latest discoveries in immunology. biochemistry and molecular biology of breast epithelial antigens and their corresponding antibodies have produced newer diagnostic tests and therapeutic approaches that are altering and improving the way we attack breast cancer. The recent spectacular and rapid advancements in the molecular biology of several of the breast epithelial antigens are presented in this volume. The way in which the final assembly of different components of the breast antigens is achieved and their functions are now within our grasp as a result of new understanding of molecular structure of these breast antigens. In addition. newer immunoassays aiming at the earliest detection of the disease are also described that integrate with promising attempts at imaging and radioimmunotherapy to set the stage for new oncological possibilities in breast cancer treatment. All these areas of intense involvement of scientists with diverse specialties are presented in this volume. which proves the need for multidisciplinary approaches to increase our chances for success in this field of medical research.
Book Synopsis Antigen and Antibody Molecular Engineering in Breast Cancer Diagnosis and Treatment by : Roberto L. Ceriani
Download or read book Antigen and Antibody Molecular Engineering in Breast Cancer Diagnosis and Treatment written by Roberto L. Ceriani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, advances in the area of immunology and breast cancer are made at an increasing rate, yielding an amount of information that can become unwieldy. The opportunity for scientists in this area of research to gather together to exchange results and working hypotheses represents, in my belief, a very attractive proposition. With this in mind, these workshops have been convened with two year intervals for the last ten years. In each of them, selected topics have been highlighted. The present workshop underscores the large advancements made in the molecular biology of both breast cancer associated antigens and their corresponding antibodies. Understanding the genetic information for the expression of these antigens has been recently advanced leading to preparation of molecularly engineered reagents for use in vaccination, serum assays, and immunizations for novel antibody production. In the anti-breast cancer antibody field the availability of molecular engineering approaches to humanize murine antibodies has induced intense interest in the creation of less immunogenic antibody forms that are now available for clinical testing. Clinical studies using anti-breast murine antibody continue to be carried out and are presented at this meeting establishing a base line for safety and efficaciousness in imaging and immunotherapy that it is hoped will be superseded by the humanized forms. Basic immunology and immunochemistry studies in breast cancer are also included in this workshop that demonstrate the fast pace at which this research is advancing in many laboratories worldwide.
Book Synopsis Breast Cancer Immunodiagnosis and Immunotherapy by : Roberto Ceriani
Download or read book Breast Cancer Immunodiagnosis and Immunotherapy written by Roberto Ceriani and published by Springer. This book was released on 2013-04-17 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: The convening of the 3rd International Workshop on Monoclonal Antibodies and Breast Cancer had the character of a self-search exercise. After almost a decade of research in the basic and applied aspects of the use of serological means to diagnose and possibly treat breast cancer several milestones have been reached. Among them a clear understanding of immunopathological use and limitations of monoclonal antibodies against breast epithelium, the complete development and clinical use of immunoassays for circulating breast epithelial antigens, the striking advances in the diagnostic use of monoclonal antibodies to estrogen and progesterone receptor proteins and the first communications on proposed immunotherapeutic use of different conjugates of anti-breast antibodies. New areas of investigation have developed in our field, some which are reaching a full blossom while others are still facing obstacles and at times a re-definition of their goals and objectives. These meetings have acted in a way as a clearing house and have permitted their attendees to derive predictions that have helped shape future research and fine-tune objectives. But above all, the re-evaluation of past research at these Workshops and the renewed excitement brought to them by new information has helped generate a momentum and enthusiasm that assures for the future large scientific gains.
Book Synopsis Breast-specific Antigens on Mammary Epithelial and Mammary Adenocarcinoma Cells in the Fischer Rat Determined by Indirect Immuno-fluorescence by : Linda Chen Einsiedler
Download or read book Breast-specific Antigens on Mammary Epithelial and Mammary Adenocarcinoma Cells in the Fischer Rat Determined by Indirect Immuno-fluorescence written by Linda Chen Einsiedler and published by . This book was released on 1979 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunological Approaches to the Diagnosis and Therapy of Breast Cancer by : G.P. Talwar
Download or read book Immunological Approaches to the Diagnosis and Therapy of Breast Cancer written by G.P. Talwar and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Once again we have gathered to discover and evaluate advances made in our ability to understand. diagnose and possibly treat breast cancer with the new reagents provided by monoclonal antibody techniques. In the last two years since our first International Workshop on Monoclonal Antibodies and Breast Cancer there has been an enormous surge in the number and quality of applications for these new reagents. Solid achievements have been made in identification and quantitation of estrogen and progesterone receptors. in histopathological diagnostic procedures. in serum diagnosis. and we are witnessing now the first attempts to treat breast cancer with immunoconjugates. Cytosolic estrogen receptors can now be quantitated with monoclonal antibodies. and also their cellular distribution can be directly assessed histologically. In addition. monoclonal antibodies to progesterone receptors have been generated that show promise in having similar uses as those to the estrogen receptor. In the field of diagnosis. the use of monoclonal antibodies has permitted the development of serological approaches for early diagnosis by identifying and measuring breast epithelial antigens in serum. and of histological approaches for establishing criteria for breast cancer dissemination and prognosis. With great expectations we are all following developments in the area of breast cancer treatment using conjugates of anti-breast epithelial monoclonal antibodies which are now confirming earlier reports in affecting breast tumor control. The recent creation of newer monoclonal antibodies and conjugates await experimentation and clinical trials to determine their value.
Book Synopsis Monoclonal Antibodies and Breast Cancer by : R. Ceriani
Download or read book Monoclonal Antibodies and Breast Cancer written by R. Ceriani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer, being a disease with very high prevalence in the female population, has permanently attracted the attention of biologists, biochemists, pathologists, surgeons, and oncologists. In the U.S. alone approximately 120,000 new cases are diagnosed and 37,000 deaths a year are recorded as an outcome. Early diagnosis, clear cut prognosis and the hope of new therapeutic approaches has spurred the enthusiasm of researchers, who with the advent of newer methodologies, tried to employ it in different approaches to the breast cancer patient. In spite of the efforts devoted towards the creation of new approaches, reagents and procedures taking advantage of special characteristics of the breast tissue were slow to come. In general, most diagnostic and prognostic techniques were those shared and applied to other carcinomas. In the early seventies we discovered the first sets of antigens associated with breast epithelial tissue both in the mouse and the human. The recognition of such group of molecules, present in the milk fat globule membrane, gave impetus to several studies in these areas. These mammary cell surface antigens proved useful in several diagnostic approaches such as radioimaging, histochemical and serum assay procedures. However, the apparently inherent limitations of polyclonal antibodies reduced the impact of these novel approaches.
Book Synopsis Immunology of Breast Cancer by : Wei-Zen Wei
Download or read book Immunology of Breast Cancer written by Wei-Zen Wei and published by IOS Press. This book was released on 2004 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue, exciting new directions are outlined by fourteen groups of investigators working on critical areas in Breast Cancer Immunology. In the clinic, patients are responding to Her-2 peptides or GM-CSF transfected tumor cell vaccines. Futhermore, tumors under vaccine induced immune attack can prime the host to additional antigens. Selected chemotherapeutic agents are used to further vaccine efficacy. These promising results highlight the value of breast cancer immunotherapy. Although the clinical progress is exciting, significant challenges remain. Many tumor-associated antigens are self-antigens and vigorous measures will be required to induce consistent and sustained anti-tumor immunity. There is a pressing need for new immunotherapy targets. In this issue, the better-characterized glycoprotein antigens and novel molecules in angiogenesis are examined as new targets of breast cancer vaccines or immunotherapy. Continued effort in new antigen identification will be critical to cancer control. Finally, a reality check is warranted. Most breast cancer cells are still elusive to immune intervention.The mechanisms of such evasion are under intense investigation and much progress has been made. Alteration in antigen processing machinery is a major route of tumor evasion.
Book Synopsis Cell Biology of Breast Cancer by : Charles M. McGrath
Download or read book Cell Biology of Breast Cancer written by Charles M. McGrath and published by . This book was released on 1980 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Casein and Carcinoembryonic Antigen Production by Normal and Neoplastic Human Mammary Epithelial Cells: an Immunocytochemical and Morphological Examination by : Andrew Irwin Gelbman
Download or read book Casein and Carcinoembryonic Antigen Production by Normal and Neoplastic Human Mammary Epithelial Cells: an Immunocytochemical and Morphological Examination written by Andrew Irwin Gelbman and published by . This book was released on 1981 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Investigations Into a Mucosal Targeted Breast Cancer Vaccine by : Julia Pinkhasov
Download or read book Investigations Into a Mucosal Targeted Breast Cancer Vaccine written by Julia Pinkhasov and published by . This book was released on 2006 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Two Types of Normal Human Breast Epithelial Cells Derived from Reduction Mammoplasty by : Chien-Yuan Kao
Download or read book Two Types of Normal Human Breast Epithelial Cells Derived from Reduction Mammoplasty written by Chien-Yuan Kao and published by . This book was released on 1994 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Leong's Manual of Diagnostic Antibodies for Immunohistology by : Runjan Chetty
Download or read book Leong's Manual of Diagnostic Antibodies for Immunohistology written by Runjan Chetty and published by Cambridge University Press. This book was released on 2016-11-28 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a unique A-Z guide to antibodies for immunohistology, this is an indispensable source for pathologists to ensure the correct application of immunohistochemistry in daily practice. Each entry includes commercial sources, clones, descriptions of stained proteins/epitopes, the full staining spectrum of normal and tumor tissues, staining pattern and cellular localization, the range of conditions of immunoreactivity, and pitfalls of the antibody's immunoprofile, giving pathologists a truly thorough quick-reference guide to sources, preparation and applications of specific antibodies. Appendices provide useful quick-reference tables of antibody panels for differential diagnoses, as well as summaries of diagnostic applications. Expanded from previous editions with over forty new entries, this handbook for diagnostic, therapeutic, prognostic and research applications of antibodies is an essential desktop book for practicing pathologists as well as researchers, residents and trainees.
Book Synopsis Synthesis of Clustered ST-Antigens for the Development of Novel Breast Cancer Vaccines by :
Download or read book Synthesis of Clustered ST-Antigens for the Development of Novel Breast Cancer Vaccines written by and published by . This book was released on 1999 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of efficient routes for the preparation of complex oligosaccharide or carbohydrate conjugates has been our immediate purpose. A more global goal would be that of recruiting the immune system to respond to malignant lesions. In our continuing chemical studies, we have undertaken to develop synthetic methodology of general applicability for the preparation of carbohydrates, in the form of glycolipids and glycopeptides, which mimic components of the accessible cell surface of tumor cells. The report herein focuses on successful syntheses of mucin related 0-linked glycopeptides, in particular the TF and 2,3-STF antigens. TF is observed on a variety of epithelial tumors and 2,3-STF is observed on a large number of breast tumors.
Book Synopsis Characterization of Epithelial Membrane Antigen Expression in Human Mammary Epithelium by Ultrastructural Immunoperoxidase Cytochemistry by : O. W. Petersen
Download or read book Characterization of Epithelial Membrane Antigen Expression in Human Mammary Epithelium by Ultrastructural Immunoperoxidase Cytochemistry written by O. W. Petersen and published by . This book was released on 1986 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunotherapy written by Harold Waters and published by . This book was released on 1981 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Janeway's Immunobiology by : Kenneth Murphy
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Book Synopsis Identification and Characterization of Tumor Antigens Associated With Breast Cancer by : Tracy A. Hampton
Download or read book Identification and Characterization of Tumor Antigens Associated With Breast Cancer written by Tracy A. Hampton and published by . This book was released on 1998 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: The host immune system can detect tumor-associated antigens (TAAs) existing on cancer cells. While TAA-based immunotherapeutic treatments for the eradication of cancer are being pursued, few TAAs have been defined. We have applied a serologically based strategy called SEREX to the identification of TAAs in the murine colon carcinoma cell line, MC38, and in human breast tumor tissue. We have identified two positive clones in MC38, one as a murine endogenous leukemia proviral envelope (env) and LTR sequence, and the other as the murine ATRX sequence. Northern blot analysis demonstrated high levels of expression of env in MC38 cells, whereas expression was absent in normal colonic epithelium. Southern blot analysis revealed several mutations at the DNA level. Northern blot analysis of ATRX demonstrated comparable levels of expression in normal versus MC38 cells, and sequence analysis indicated no mutations. Polynucleotide immunization strategies with these antigens are being pursued. A potential TAA from breast tissue has been isolated and is being characterized. These results demonstrate the potential of SEREX screening to identify tumor antigens which may be utilized as novel targets for cancer immunotherapy.
