Brain Stimulation

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Transcranial Brain Stimulation

Author : Carlo Miniussi
Publisher : CRC Press
ISBN 13 : 1439875715
Total Pages : 465 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Transcranial Brain Stimulation by : Carlo Miniussi

Download or read book Transcranial Brain Stimulation written by Carlo Miniussi and published by CRC Press. This book was released on 2012-12-03 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES), these non-invasive brain stimulation (NIBS) techniques have been used to investigate the state of cortical excitability, and the excitability of the cortico-cortical and corticospinal pathways. In addition, these techniques have been found to induce neuroplasticity—a significant breakthrough in our understanding of the brain at work. Transcranial Brain Stimulation presents a wide range of possible brain stimulation applications and discusses what new information can be gained from using this technique on the dynamics of brain functions, hierarchical organization, and effective connectivity. Implications of recent findings related to the therapeutic application are discussed by an international group of leading experts, who present practical guidance on the use of each technique, and catalog the results of numerous TMS and tES studies on biological and behavioral effects.

Brain Stimulation

Author : Emily Bell
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128080329
Total Pages : 784 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Brain Stimulation by : Emily Bell

Download or read book Brain Stimulation written by Emily Bell and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: The consideration of ethical and social issues related to current uses of deep brain stimulation (DBS) as well as investigational uses should now be an integral part of contemporary DBS practice. Scholarship, interdisciplinary work groups, and peer processes have helped articulate standards that need to be respected and implemented in current DBS practice. Integrating new knowledge and interdisciplinary ethical perspectives could be considered a sign of the maturity and rigor of a DBS program. Still, investigational uses of DBS carry tremendous hope but also touch on sensitive and thorny ethical questions. These questions can benefit from the ethical wisdom generated for standard uses of DBS but also challenge current practices and professional conduct. Realizing this, interdisciplinary expert groups have been convened to identify and flesh out ethical guideposts for cutting-edge research in DBS. By implementing these ethical frameworks, DBS is an opportunity to develop promising treatments for a set of vulnerable and sometimes underserved patients while keeping their best interests in sight.

Brain Stimulation

Author : Günther Deuschl
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128080167
Total Pages : 784 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Brain Stimulation by : Günther Deuschl

Download or read book Brain Stimulation written by Günther Deuschl and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep brain stimulation is one of the most effective treatments of Parkinson’s disease (PD). This report summarizes the state of the art as at January 2013. Stimulation of the subthalamic nucleus is the most commonly used approach. It improves the core motor symptoms better than medication in patients with advanced disease. It also improves the majority of nonmotor symptoms, such as mood, impulse control disorders, sleep, and some autonomic dysfunctions. Quality of life (QoL) is improved significantly more than with medication. Long-term data show that the treatment is effective for up to 10 years, but the late appearance of l-dopa-resistant symptoms is seemingly not influenced. Internal globus pallidus (GPi) stimulation is less well studied but seems to have similar short-term efficacy. Importantly l-dopa use cannot be reduced with GPi DBS, which is a major disadvantage for patients suffering from medication side-effects, although gait may be influenced more positively. Although short-term QoL improvement seems to be similar to that for subthalamic nucleus (STN) DBS – gait and speech may be better improved – long-term data are rare for GPi DBS. Thalamic stimulation in the ventral intermediate nucleus (VIM) is applied only in tremor-dominant elderly patients. The treatment improves the dopa-sensitive symptoms and effectively reduces fluctuations leading to an overall QoL improvement. Although most of the controlled studies have been on advanced PD, the recently published EARLYSTIM study suggests that even patients with a very short duration of their fluctuations and dyskinesia are doing significantly better with neurostimulation in terms of QoL and all major motor outcome parameters.

Brain Stimulation

Author : Irving Reti
Publisher : John Wiley & Sons
ISBN 13 : 111856829X
Total Pages : 364 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Brain Stimulation by : Irving Reti

Download or read book Brain Stimulation written by Irving Reti and published by John Wiley & Sons. This book was released on 2015-05-11 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain stimulation technologies are both tools to probe brain function and to provide therapeutic options for patients with neuropsychiatric disease where pharmacological options are not viable. Although the field has been in existence for over seventy years, research interest in brain stimulation has been on the rise particularly in the last two decades. Brain Stimulation: Methodologies and Interventions is an introduction to the field of brain stimulation technology and its applications. The book explores how brainstimulating technologies work in the context of brain pathways that mediate normal and abnormal brain function. Chapters cover neuroanatomy and activity dependent changes in neuronal function triggered by brain stimulation, as well as applications of brain stimulation technologies themselves, including noninvasive procedures that rely on convulsive or seizure therapeutics, and non-convulsive therapies such as magnetic and electrical brain stimulation. Authored by an international group of leaders in the field, Brain Stimulation is a valuable resource for both neuroscience researchers and clinicians.

Brain Stimulation

Author : Erlick A.C. Pereira
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128080299
Total Pages : 784 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Brain Stimulation by : Erlick A.C. Pereira

Download or read book Brain Stimulation written by Erlick A.C. Pereira and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep brain stimulation (DBS) is a neurosurgical intervention whose efficacy, safety, and utility have been shown in the treatment of movement disorders. For the treatment of chronic pain refractory to medical therapies, many prospective case series have been reported, but few have published findings from patients treated during the past decade using current standards of neuroimaging and stimulator technology. We summarize the history, science, selection, assessment, surgery, and personal clinical experience of DBS of the ventral posterior thalamus, periventricular/periaqueductal gray matter, and, latterly, the rostral anterior cingulate cortex (Cg24) in 100 patients treated now at two centers (John Radcliffe Hospital, Oxford, UK, and Hospital de São João, Porto, Portugal) over 12 years. Several experienced centers continue DBS for chronic pain with success in selected patients, in particular those with pain after amputation, brachial plexus injury, stroke, and cephalalgias including anesthesia dolorosa. Other successes include pain after multiple sclerosis and spine injury. Somatotopic coverage during awake surgery is important in our technique, with cingulate DBS considered for whole-body pain or after unsuccessful DBS of other targets. Findings discussed from neuroimaging modalities, invasive neurophysiological insights from local field potential recording, and autonomic assessments may translate into improved patient selection and enhanced efficacy, encouraging larger clinical trials.

Electrical Brain Stimulation in Psychiatric Disorders. Contributions from Research in Animal Models

Author : Kris Van Kuyck
Publisher : Leuven University Press
ISBN 13 : 9789058675545
Total Pages : 182 pages
Book Rating : 4.6/5 (755 download)

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Book Synopsis Electrical Brain Stimulation in Psychiatric Disorders. Contributions from Research in Animal Models by : Kris Van Kuyck

Download or read book Electrical Brain Stimulation in Psychiatric Disorders. Contributions from Research in Animal Models written by Kris Van Kuyck and published by Leuven University Press. This book was released on 2006 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Brain Stimulation

Author : Irving Reti
Publisher : John Wiley & Sons
ISBN 13 : 1118568397
Total Pages : 368 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Brain Stimulation by : Irving Reti

Download or read book Brain Stimulation written by Irving Reti and published by John Wiley & Sons. This book was released on 2015-03-12 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain stimulation technologies are both tools to probe brain function and to provide therapeutic options for patients with neuropsychiatric disease where pharmacological options are not viable. Although the field has been in existence for over seventy years, research interest in brain stimulation has been on the rise particularly in the last two decades. Brain Stimulation: Methodologies and Interventions is an introduction to the field of brain stimulation technology and its applications. The book explores how brainstimulating technologies work in the context of brain pathways that mediate normal and abnormal brain function. Chapters cover neuroanatomy and activity dependent changes in neuronal function triggered by brain stimulation, as well as applications of brain stimulation technologies themselves, including noninvasive procedures that rely on convulsive or seizure therapeutics, and non-convulsive therapies such as magnetic and electrical brain stimulation. Authored by an international group of leaders in the field, Brain Stimulation is a valuable resource for both neuroscience researchers and clinicians.

Brain Stimulation

Author : Ji Hyun Ko
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128080140
Total Pages : 784 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Brain Stimulation by : Ji Hyun Ko

Download or read book Brain Stimulation written by Ji Hyun Ko and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of functional brain imaging techniques, including positron emission tomography (PET), single-photon emission computed tomography (SPECT), and functional magnetic resonance imaging (fMRI), has allowed for monitoring neuronal and neurochemical activities in the living human brain and identifying abnormal changes in various neurological and psychiatric diseases. Combining these methods with techniques such as deep brain stimulation (DBS) and transcranial magnetic stimulation (TMS) has greatly advanced our understanding of the effects of such treatment on brain activity at targeted regions as well as specific disease-related networks. Indeed, recent network-level analysis focusing on inter-regional covarying activities in data interpretation has unveiled several key mechanisms underlying the therapeutic effects of brain stimulation. However, non-negligible discrepancies have been reported in the literature, attributable in part to the heterogeneity of both imaging and brain stimulation techniques. This chapter summarizes recent studies that combine brain imaging and brain stimulation, and includes discussion of future direction in these lines of research.

Brain Stimulation

Author : Cameron C. Mcintyre
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128080116
Total Pages : 784 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Brain Stimulation by : Cameron C. Mcintyre

Download or read book Brain Stimulation written by Cameron C. Mcintyre and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep brain stimulation (DBS) is an effective clinical treatment for several medically refractory neurological disorders. However, even after decades of clinical success, explicit understanding of the response of neurons to applied electric fields remains limited, and scientific definition of the therapeutic mechanisms of DBS remains elusive. In addition, it is presently unclear which electrode designs and stimulation paradigms are optimal for maximal therapeutic benefit and minimal side-effects with DBS. Detailed computer modeling of DBS has emerged recently as a powerful technique to enhance our understanding of the effects of DBS and to create a virtual testing ground for new stimulation strategies. This chapter summarizes the fundamentals of neurostimulation modeling, presents some scientific contributions of computer models to the field of DBS, and demonstrates the application of DBS modeling tools to augment the clinical utility of DBS.

Deep Brain Stimulation

Author : Kendall H. Lee
Publisher : CRC Press
ISBN 13 : 1315341093
Total Pages : 486 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Deep Brain Stimulation by : Kendall H. Lee

Download or read book Deep Brain Stimulation written by Kendall H. Lee and published by CRC Press. This book was released on 2016-12-08 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep brain stimulation (DBS) is a widely used therapy for movement disorders such as Parkinson's disease, essential tremor, and dystonia. Its therapeutic success has led to the application of DBS for an increasing spectrum of conditions. However, the fundamental relationships between neural activation, neurochemical transmission, and clinical outcomes during DBS are not well understood. Drawing on the clinical and research expertise of the Mayo Clinic Neural Engineering Laboratories, this book addresses the history of therapeutic electrical stimulation of the brain, its current application and outcomes, and theories about its underlying mechanisms. It reviews research on measures of local stimulation–evoked neurochemical release, imaging research on stimulation-induced neural circuitry activation, and the state of the art on closed-loop feedback devices for stimulation delivery.

Models and Simulations of the Electric Field in Deep Brain Stimulation

Author : Fabiola Alonso
Publisher : Linköping University Electronic Press
ISBN 13 : 917685261X
Total Pages : 99 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Models and Simulations of the Electric Field in Deep Brain Stimulation by : Fabiola Alonso

Download or read book Models and Simulations of the Electric Field in Deep Brain Stimulation written by Fabiola Alonso and published by Linköping University Electronic Press. This book was released on 2018-09-10 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep brain stimulation (DBS) is an established surgical therapy for movement disorders such as Parkinson’s disease (PD) and essential tremor (ET). A thin electrode is implanted in a predefined area of the brain with the use of stereotactic neurosurgery. In the last few years new DBS electrodes and systems have been developed with possibilities for using more parameters for control of the stimulation volume. In this thesis, simulations using the finite element method (FEM) have been developed and used for investigation of the electric field (EF) extension around different types of DBS lead designs (symmetric, steering) and stimulation modes (voltage, current). The electrode surrounding was represented either with a homogeneous model or a patient-specific model based on individual preoperative magnetic resonance imaging (MRI). The EF was visualized and compared for different lead designs and operating modes. In Paper I, the EF was quantitatively investigated around two lead designs (3389 and 6148) simulated to operate in voltage and current mode under acute and chronic time points following implantation.Simulations showed a major impact on the EF extension between postoperative time points which may explain the clinical decisions to change the stimulation amplitude weeks after implantation. In Paper II, the simulations were expanded to include two leads having steering function (6180, Surestim1) and patient-specific FEM simulations in the zona incerta. It was found that both the heterogeneity of the tissue and the operating mode, influence the EF distribution and that equivalent contact configurations of the leads result in similar EF. The steering mode presented larger volumes in current mode when using equivalent amplitudes. Simulations comparing DBS and intraoperative stimulation test using a microelectrode recording (MER) system (Paper III), showed that several parallel MER leads and the presence of the non-active DBS contacts influence the EF distribution and that the DBS EF volume can cover, but also extend to, other anatomical areas. Paper IV introduces a method for an objective exploitation of intraoperative stimulation test data in order to identify the optimal implant position in the thalamus of the chronic DBS lead. Patient-specific EF simulations were related to the anatomy with the help of brain atlases and the clinical effects which were quantified by accelerometers. The first results indicate that the good clinical effect in ET is due to several structures around the ventral intermediate nucleus of the thalamus.

Brain Stimulation

Author : Filippo Agnesi
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128080108
Total Pages : 784 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Brain Stimulation by : Filippo Agnesi

Download or read book Brain Stimulation written by Filippo Agnesi and published by Elsevier Inc. Chapters. This book was released on 2013-11-11 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic deep brain stimulation (DBS) has become a widely accepted surgical treatment for medication-refractory movement disorders and is under evaluation for a variety of neurological disorders. In order to create opportunities to improve treatment efficacy, streamline parameter selection, and foster new potential applications, it is important to have a clear and comprehensive understanding of how DBS works. Although early hypothesis proposed that high-frequency electrical stimulation inhibited neuronal activity proximal to the active electrode, recent studies have suggested that the output of the stimulated nuclei is paradoxically activated by DBS. Such regular, time-locked output is thought to override the transmission of pathological bursting and oscillatory activity through the stimulated nuclei, as well as inducing synaptic plasticity and network reorganization. This chapter reviews electrophysiological experiments, biochemical analyses, computer modeling and imaging studies positing that, although general principles exist, the therapeutic mechanism(s) of action depend both on the site of stimulation and on the disorder being treated.

Deep Brain Stimulation Think Tank: Updates in Neurotechnology and Neuromodulation, Volume II

Author : Adolfo Ramirez-Zamora
Publisher : Frontiers Media SA
ISBN 13 : 2889764311
Total Pages : 196 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Deep Brain Stimulation Think Tank: Updates in Neurotechnology and Neuromodulation, Volume II by : Adolfo Ramirez-Zamora

Download or read book Deep Brain Stimulation Think Tank: Updates in Neurotechnology and Neuromodulation, Volume II written by Adolfo Ramirez-Zamora and published by Frontiers Media SA. This book was released on 2022-06-27 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Deep Brain Stimulation Management

Author : William J. Marks, Jr
Publisher : Cambridge University Press
ISBN 13 : 1316033627
Total Pages : pages
Book Rating : 4.3/5 (16 download)

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Book Synopsis Deep Brain Stimulation Management by : William J. Marks, Jr

Download or read book Deep Brain Stimulation Management written by William J. Marks, Jr and published by Cambridge University Press. This book was released on 2015-09-03 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise guide to deep brain stimulation (DBS) outlines a practical approach to the use of this paradigm-shifting therapy for neurologic and psychiatric disorders. Fully revised throughout, the new edition provides extensive information about the application of DBS to movement disorders, and includes new chapters on DBS to treat epilepsy and psychiatric conditions. With the evolution of surgical techniques for DBS lead implantation, a brand new section focused on interventional MRI approaches is also included. All key aspects of DBS practice are covered, including patient selection, device programming to achieve optimal symptom control, long-term management, and troubleshooting. It is a guide to be kept in the clinic and consulted in the course of managing patients being considered for, or treated with, DBS. With contributions from some of the most experienced clinical leaders in the field, this is a must-have reference guide for any clinician working with DBS patients.

Transcranial Brain Stimulation

Author : Carlo Miniussi
Publisher : CRC Press
ISBN 13 : 1439875707
Total Pages : 468 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Transcranial Brain Stimulation by : Carlo Miniussi

Download or read book Transcranial Brain Stimulation written by Carlo Miniussi and published by CRC Press. This book was released on 2012-12-03 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES), these non-invasive brain stimulation (NIBS) techniques have been used to investigate the state of cortical excitability, and the excitability of the cortico-cortical and corticospinal pathways. In addition, these techniques have been found to induce neuroplasticity—a significant breakthrough in our understanding of the brain at work. Transcranial Brain Stimulation presents a wide range of possible brain stimulation applications and discusses what new information can be gained from using this technique on the dynamics of brain functions, hierarchical organization, and effective connectivity. Implications of recent findings related to the therapeutic application are discussed by an international group of leading experts, who present practical guidance on the use of each technique, and catalog the results of numerous TMS and tES studies on biological and behavioral effects.

Textbook of Cortical Brain Stimulation

Author : Sergio Canavero
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110412624
Total Pages : 294 pages
Book Rating : 4.1/5 (14 download)

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Book Synopsis Textbook of Cortical Brain Stimulation by : Sergio Canavero

Download or read book Textbook of Cortical Brain Stimulation written by Sergio Canavero and published by Walter de Gruyter GmbH & Co KG. This book was released on 2015-01-29 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developed over the past 25 years, Cortical Brain Stimulation has emerged as a brand new, cutting-edge option for the treatment of intractable neurological and psychiatric disorders. Devoid of the mortality and disabling morbidity that may accompany deep brain stimulation, stimulating the cortex with a minimally invasive surgical approach had initially proved its worth for the treatment of Central and other Neuropathic Pain Syndromes and later for Parkinson Disease, Dystonia, Stroke and Coma rehabilitation, Epilepsy, Depression and Tinnitus. Written by many of the pioneers in the field, this authoritative treatise is a comprehensive presentation - from surgical details, to clinical results and mechanisms of action. It also provides the busy clinician with comparisons with non-invasive cortical stimulation techniques, such as TMS and tDCS. No other book deals with this form of brain stimulation. The clinician will harness the power of this formidable new therapeutic option, which is being further refined with the advent of closed-loop stimulation. Dr Canavero deciphered the genesis of the central pain syndromes, introduced extradural cortical stimulation for Parkinson Disease and the vegetative state and co-introduced extradural cortical stimulation for stroke rehabilitation. He made worldwide news in 2008 for partially restoring consciousness in two vegetative patients, in 2013 for proposing the HEAVEN/GEMINI protocol for human head transplantation and in 2014 for pushing brain stimulation in the setting of criminal psychopathy. His books include: Central Pain Syndrome, Cambridge Univ. Press, 2011 (2nd ed.), Textbook of therapeutic cortical stimulation, Nova Sci, 2009 and two books in Italian on human sexual behavior.

Deep Brain Stimulation and Epilepsy

Author : Hans O. Lüders
Publisher : CRC Press
ISBN 13 : 1000148955
Total Pages : 396 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Deep Brain Stimulation and Epilepsy by : Hans O. Lüders

Download or read book Deep Brain Stimulation and Epilepsy written by Hans O. Lüders and published by CRC Press. This book was released on 2020-08-26 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep brain stimulation has been used effectively for many years to treat patients suffering from Parkinson's disease. Now, neurologists and neurosurgeons are using electric pulse generators to block abnormal activity, i.e. epileptic fits. Promising research results indicate that electric pulses implanted deep in the brain can affect neurocircuitry and help stop oncoming seizures. Supplying a solid background on brain stimulation and its application to epilepsy, Deep Brain Stimulation and Epilepsy provides a historical overview, explores pathogenesis of brain stimulation, discusses animal experiments and human studies, and explores future prospects of brain stimulation for epileptic control. The editor and his team of contributors distill information drawn directly from the literature into one convenient resource.