Clostridial Neurotoxins

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Publisher : Springer Science & Business Media
ISBN 13 : 3642851738
Total Pages : 283 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Clostridial Neurotoxins by : Cesare Montecucco

Download or read book Clostridial Neurotoxins written by Cesare Montecucco and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tetanus has been known from the very beginning of medical literature since it was first described by Hyppocrates of Cos in the fifth century B.C. For 24 centuries it was considered a neuro logical disease until the breakthrough of CARLE and RATIONE (1884) who demonstrated its infectious etiology. Following the establishment of purified cultures of Clostridium tetani(KITASATO 1889), FABER (1890), and TIZZONI and CATIANI (1890) demon strated that the disease is actually an intoxication caused by a proteic neurotoxin. This toxin was shown by BRUSHCHETIINI (1892) to move retroaxonally and to act at the spinal cord level. Soon thereafter VAN ERMENGEN (1897) demonstrated that botu lism is also due to intoxication with a protein toxin produced by bacteria of the genus Clostridium. These bacteria and their spores and ubiquitous, and the majority of them do not produce neurotoxins. The selective advantage of producing such potent toxin is still a matter of speculation (see Popoff, this volume). The next major advance was the discovery that tetanus neurotoxin 1 can be converted by formaldehyde treatment to a nonpathogenic but still fully immunogenic form, and that this can be used successfully as a vaccine to prevent tetanus (RAMON and DESCOMBEY 1925). Similar vaccines (toxoids) can be prepared with botulism neurotoxins (see MiDDLEBROOK and BROWN, this volume). The prevention oftetanus by vaccination (see Galatzka and Gasse, this volume) is one of the great successes of basic research coupled with an efficient public medicine service.

Clinical Infectious Diseases Study Guide

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Author :
Publisher : Springer Nature
ISBN 13 : 3030508730
Total Pages : 357 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Clinical Infectious Diseases Study Guide by : Joseph Domachowske

Download or read book Clinical Infectious Diseases Study Guide written by Joseph Domachowske and published by Springer Nature. This book was released on 2020-08-05 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is meticulously designed for the busy student, trainee, or seasoned physician looking to enhance or refresh skills in infectious diseases. It is intended to provide a solid resource for students and physicians in need of a concise yet comprehensive background of the material. Each chapter begins with a summary of the topic, a brief case description, definitions, critical teaching points, and tables, figures, photos, and other visual materials to reinforce learning. The chapters take a systems based approach to infections before concluding with the essentials of diagnostic microbiology to leave users with a practical toolkit for real-world clinics. Authored by two expert educators and dual infectious diseases and pediatrics specialists, Clinical Infectious Diseases Study Guide is the only updated study guide designed for medical students, fellows, residents, and trainees who need a strong foundation in infectious diseases. This includes infectious disease specialists in both adult and pediatric care, various internal medicine subspecialists, and hospitalists.

Botulism in the United States, 1899-1973

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Publisher :
ISBN 13 :
Total Pages : 48 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Botulism in the United States, 1899-1973 by : United States. Public Health Service

Download or read book Botulism in the United States, 1899-1973 written by United States. Public Health Service and published by . This book was released on 1974 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clostridium Botulinum

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Publisher : Routledge
ISBN 13 : 135146003X
Total Pages : 428 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Clostridium Botulinum by : Hauschild

Download or read book Clostridium Botulinum written by Hauschild and published by Routledge. This book was released on 2018-12-13 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: An in-depth resource addressing the ecology of Clostridium botulinum which affects the degree of food contamination, and its control in various foods. The text summarizes worldwide data on this organism in food and the environment and the principles of its control in specific foods and products.

Botulism and Food Preservation

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Publisher :
ISBN 13 :
Total Pages : 282 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Botulism and Food Preservation by : Gerald Rowley Leighton

Download or read book Botulism and Food Preservation written by Gerald Rowley Leighton and published by . This book was released on 1923 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Zoonoses E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323070922
Total Pages : 264 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Handbook of Zoonoses E-Book by : Joann Colville

Download or read book Handbook of Zoonoses E-Book written by Joann Colville and published by Elsevier Health Sciences. This book was released on 2007-05-23 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essential, authoritative handbook provides clear, accurate coverage of zoonoses — diseases that can spread from animals to humans. The consistent format helps you quickly locate key information, such as how each disease affects the host, how it is spread, how it is treated, and necessary safety precautions. It also discusses the importance of educating animal owners about the public health implications of zoonoses and how to prevent them from spreading. - Clear, concise coverage helps you respond quickly when presented with diseases that could potentially spread between patients, clients, and staff in the veterinary clinic. - Each disease entry begins with a chart of its potential morbidity (the rate of incidence of a disease) and mortality (death rate), giving you at-a-glance access to the chance of contracting the disease and the severity of the disease if contracted. - Clinically relevant coverage includes information on the etiology (bacterial, viral, parasitic, etc.), most common nonhuman hosts, transmission modes, course of the disease, clinical signs in animals and humans, diagnostic tests, prevention, and general advice. - Essential information on preventing the spread of disease helps you educate clients about how to protect themselves and their animals from zoonoses. - Coverage of diseases such as mad cow disease, West Nile virus, rabies, and anthrax, prepares you to answer client questions about diseases that are in the public eye.

Botulism

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Publisher : Infobase Publishing
ISBN 13 : 1604132353
Total Pages : 145 pages
Book Rating : 4.6/5 (41 download)

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Book Synopsis Botulism by : Donald Emmeluth

Download or read book Botulism written by Donald Emmeluth and published by Infobase Publishing. This book was released on 2010 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores the history, causes, symptoms, treatment, and prevention of botulism.

Beyond Anthrax

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Publisher : Springer Science & Business Media
ISBN 13 : 1597453269
Total Pages : 382 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Beyond Anthrax by : Larry I. Lutwick

Download or read book Beyond Anthrax written by Larry I. Lutwick and published by Springer Science & Business Media. This book was released on 2008-12-15 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological warfare has, unfortunately, in the post 9/11 world become a significant topic of discussion in both the medical and lay presses. In the wake of the biological "letter bombs" containing anthrax spores, the possibility of biologic and/or toxic attacks on civilians in any part of the world became no longer a possibility. It is now part of common discussion and consciousness. This book presents the history of the topics and clinically relevant discussions on those high risk (Category A) diseases beyond anthrax as well as a number of infections and toxins at the Category B level. Importantly, in addition, the text includes sections on Public Health Infrastructure, Public Health Law, Surveillance, Mental Health Management and Media Role all of which relate to epidemics of any sort, not just intentional biological events. Beyond Anthrax: The Weaponization of Infectious Diseases is a product that should serve as a reference point for clinicians, epidemiologists and public health personnel to understand in practical detail many of the aspects of weapons of biowarfare as well as the appropriate responses to them.

Botulism

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Publisher :
ISBN 13 :
Total Pages : 344 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Botulism by : Keith Harrower Lewis (ed.)

Download or read book Botulism written by Keith Harrower Lewis (ed.) and published by . This book was released on 1964 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Practical Guide to Botulinum Toxin Procedures

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451154496
Total Pages : 320 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis A Practical Guide to Botulinum Toxin Procedures by : Rebecca Small

Download or read book A Practical Guide to Botulinum Toxin Procedures written by Rebecca Small and published by Lippincott Williams & Wilkins. This book was released on 2012-01-24 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Practical Guide to Botulinum Toxin Procedures is one of four books in the new Cosmetic Procedures for Primary Care series. This series offers guidance to primary care practitioners who wish to expand their practice to minimally invasive cosmetic procedures. Whether the physician is just getting started or well versed in aesthetic medicine, this series can be used as a routine quick reference for current aesthetic procedures that can be readily incorporated into office practice. The series will put these cosmetic treatments into the hands of the physician the patient knows and trusts the most, and will bring primary care practitioners increased autonomy, improved patient satisfaction, and added reimbursement. This book provides thoroughly illustrated step-by-step instructions on botulinum toxin injection procedures and advice on managing common issues seen in follow-up visits. Each chapter focuses on a single procedure and reviews all relevant anatomy, including target muscles and their functions and muscles to be avoided. Injection points and the injection Safety Zones are highlighted to help practitioners perform the procedures more effectively and minimize complication risks. Initial chapters cover treatment in the upper third of the face for frown lines, horizontal forehead lines, and crow's feet—procedures suited for practitioners who are getting started with cosmetic botulinum toxin treatments. Subsequent chapters cover more advanced face and neck procedures and treatment of axillary hyperhidrosis.

Botulinum and Tetanus Neurotoxins

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Author :
Publisher :
ISBN 13 : 9781475795431
Total Pages : 710 pages
Book Rating : 4.7/5 (954 download)

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Book Synopsis Botulinum and Tetanus Neurotoxins by : B. R. Dasgupta

Download or read book Botulinum and Tetanus Neurotoxins written by B. R. Dasgupta and published by . This book was released on 2014-01-15 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Deadly Dinner Party

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Publisher : Yale University Press
ISBN 13 : 0300154992
Total Pages : 260 pages
Book Rating : 4.3/5 (1 download)

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Book Synopsis The Deadly Dinner Party by : Jonathan A. Edlow

Download or read book The Deadly Dinner Party written by Jonathan A. Edlow and published by Yale University Press. This book was released on 2009-09-22 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Picking up where Berton Roueché's The Medical Detectives left off, The Deadly Dinner Party presents fifteen edge-of-your-seat, real-life medical detective stories written by a practicing physician. Award-winning author Jonathan Edlow, M.D., shows the doctor as detective and the epidemiologist as elite sleuth in stories that are as gripping as the best thrillers.In these stories a notorious stomach bug turns a suburban dinner party into a disaster that almost claims its host; a diminutive woman routinely eats more than her football-playing boyfriend but continually loses weight; a young executive is diagnosed with lung cancer, yet the tumors seem to wax and wane inexplicably. Written for the lay person who wishes to better grasp how doctors decipher the myriad clues and puzzling symptoms they often encounter, each story presents a very different case where doctors must work to find the accurate diagnosis before it is too late. Edlow uses his unique ability to relate complex medical concepts in a writing style that is clear, engaging and easily understandable. The resulting stories both entertain us and teach us much about medicine, its history and the subtle interactions among pathogens, humans, and the environment.

Biological Toxins and Bioterrorism

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Publisher : Springer
ISBN 13 : 9789400758681
Total Pages : 0 pages
Book Rating : 4.7/5 (586 download)

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Book Synopsis Biological Toxins and Bioterrorism by : P. Gopalakrishnakone

Download or read book Biological Toxins and Bioterrorism written by P. Gopalakrishnakone and published by Springer. This book was released on 2015-01-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of toxin structure, physiology, utility, and countermeasures including regulatory issues, it was thus aimed to compile a book on biotoxins and bioweapons. This reference work in the Toxinology handbook series gathers together knowledge from around the globe about naturally inspired and manufactured biological weapons. The authors describe how they work; how authorities may detect their presence, prevent their use, and diagnose their impacts; and the means by which medical and paramedical professionals may treat victims. Also described are how they have been used to further our knowledge and what insights they have given us into evolutionary and physiological processes. Finally, it is also discussed how these toxins can be used as therapeutics and what the implications of such therapeutics are to their use as biothreat agents. This volume provides a reference accessible to scientists, educators, and medical experts alike with an interest in biotoxins, focusing on the major toxins used as bioweapons. Regulatory agencies will also benefit from the information provided in this book. Some in the intended audience may need to understand how they elicit their effects and how we can defend ourselves against them. Others may be interested in the sometimes colorful histories that surround this subset of biotoxins that can be and, in some cases, have been used as weapons.

Human Emerging and Re-emerging Infections

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Publisher : John Wiley & Sons
ISBN 13 : 1118644646
Total Pages : 2365 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Human Emerging and Re-emerging Infections by : Sunit Kumar Singh

Download or read book Human Emerging and Re-emerging Infections written by Sunit Kumar Singh and published by John Wiley & Sons. This book was released on 2015-11-09 with total page 2365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the “novel” nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.

Clostridial Diseases of Animals

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Publisher : John Wiley & Sons
ISBN 13 : 1118728408
Total Pages : 356 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Clostridial Diseases of Animals by : Francisco A. Uzal

Download or read book Clostridial Diseases of Animals written by Francisco A. Uzal and published by John Wiley & Sons. This book was released on 2016-05-31 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clostridial Diseases of Animals is the first book to focus on clostridial diseases in domestic and wild animals, offering a comprehensive reference on these common diseases. Provides a single resource for all aspects of clostridial diseases Presents current, comprehensive information with a focus on clinical relevance Covers each disease in depth, including etiology, epidemiology, clinics, gross pathology, histopathology, diagnostics, diagnostic criteria, prophylaxis, control, and treatment Written by the world-leading experts in the field of clostridial diseases in animals Offers photographs and summary tables to support the concepts discussed in the text and aid in recognition

Botulinum Neurotoxin and Tetanus Toxin

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Publisher :
ISBN 13 :
Total Pages : 448 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Botulinum Neurotoxin and Tetanus Toxin by : Lance L. Simpson

Download or read book Botulinum Neurotoxin and Tetanus Toxin written by Lance L. Simpson and published by . This book was released on 1989 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Botulinum Neurotoxin and Tetanus Toxin ...

Botulinum Neurotoxins

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Author :
Publisher : Springer
ISBN 13 : 9783642448898
Total Pages : 0 pages
Book Rating : 4.4/5 (488 download)

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Book Synopsis Botulinum Neurotoxins by : Andreas Rummel

Download or read book Botulinum Neurotoxins written by Andreas Rummel and published by Springer. This book was released on 2015-01-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application.