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Bioseparation Process Science
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Book Synopsis Bioseparation Process Science by : Antonio A. Garciá
Download or read book Bioseparation Process Science written by Antonio A. Garciá and published by Wiley. This book was released on 1999-05-11 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended for use of students who need to learn the techniques of protein purification, large-scale processing and design, and scale-up for the biotechnology and pharmaceutical industries. This book will fill the present gap in the market for an in-depth bioseparations text. It covers all the current techniques used by researchers and industrial professionals and is an excellent source for students and scientists.
Book Synopsis Bioseparations Science and Engineering by : Roger G. Harrison
Download or read book Bioseparations Science and Engineering written by Roger G. Harrison and published by Oxford University Press. This book was released on 2015-01-27 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for undergraduates, graduate students, and industry practitioners, Bioseparations Science and Engineering fills a critical need in the field of bioseparations. Current, comprehensive, and concise, it covers bioseparations unit operations in unprecedented depth. In each of the chapters, the authors use a consistent method of explaining unit operations, starting with a qualitative description noting the significance and general application of the unit operation. They then illustrate the scientific application of the operation, develop the required mathematical theory, and finally, describe the applications of the theory in engineering practice, with an emphasis on design and scaleup. Unique to this text is a chapter dedicated to bioseparations process design and economics, in which a process simular, SuperPro Designer® is used to analyze and evaluate the production of three important biological products. New to this second edition are updated discussions of moment analysis, computer simulation, membrane chromatography, and evaporation, among others, as well as revised problem sets. Unique features include basic information about bioproducts and engineering analysis and a chapter with bioseparations laboratory exercises. Bioseparations Science and Engineering is ideal for students and professionals working in or studying bioseparations, and is the premier text in the field.
Book Synopsis Bioseparations Science and Engineering by : Roger G. Harrison
Download or read book Bioseparations Science and Engineering written by Roger G. Harrison and published by Topics in Chemical Engineering. This book was released on 2015 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preceded by: Bioseparations science and engineering / Roger G. Harrison ... [et al.]. c2003.
Book Synopsis Engineering Processes for Bioseparations by : LAURENCE R. WEATHERLEY
Download or read book Engineering Processes for Bioseparations written by LAURENCE R. WEATHERLEY and published by Elsevier. This book was released on 2013-10-22 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of biotechnology in chemical synthesis offers up numerous advantages to the engineer in the process industries, but it also presents a number of fundamental challenges and difficulties which impinge directly on separation process requirements. The use of biochemical separations has grown significantly during the past decade, and is especially used in process industries such as healthcare and food processing. However it is becoming increasingly more important in areas such as recycling and waste-water treatment and as industry shifts towards cleaner processes biochemical separations will continue to grow. The two main objectives of this book are to focus on the application of existing separation process techniques to the recovery and purification of biologically derived products and to examine the state of knowledge of new techniques which have future potential. Within these objectives the complexities and breadth of problems associated with biological separations are discussed, specific engineering techniques are featured and their adaptation to biochemical separations are highlighted.
Book Synopsis Handbook of Bioseparations by : Satinder Ahuja
Download or read book Handbook of Bioseparations written by Satinder Ahuja and published by Elsevier. This book was released on 2000-06-23 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is generally recognized that the commercial success of biotechnology products is highly dependent on the successful development and application of high-powered separation and purification methods. In this practical and authoritative handbook, the separation of proteins, nucleic acids, and oligonucleotides from biological matrices is covered from analytical to process scales. Also included in a chapter on the separation of monoclonal antibodies, which have found numerous uses as therapeutic and diagnostic agents. Analytical techniques include an interesting montage of chromatographic methods, capillary electrophoresis, isoelectric focusing, and mass spectrometry. Among separation and purification methods, liquid-liquid distribution, displacement chromatography, expanded bed adsorption, membrane chromatography, and simulated moving bed chromatography are covered at length. Regulatory and economic considerations are addressed, as are plant and process equipment and engineering process control. A chapter on future developments highlights the application of DNA chip arrays as well as evolving methodologies for a large number of drugs that are under development for treatment of cancer, AIDS, rheumatoid arthritis, and Alzheimer's disease. Handbook of Bioseparations serves as an essential reference and guidebook for separation scientists working in the pharmaceutical and biotechnology industries, academia, and government laboratories. Key Features * Covers bioseparations of proteins, nucleic acids, and monoclonal antibodies * Encompasses both analytical and process-scale methods * Elucidates the importance of engineering process control * Details selection of plant and process equipment * Addresses economic considerations * Discusses future developments
Book Synopsis Bioseparations Downstream Processing for Biotechnology by : Paul A. Belter
Download or read book Bioseparations Downstream Processing for Biotechnology written by Paul A. Belter and published by Wiley-Interscience. This book was released on 1994-10-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a concise introduction to the separation and purification of biochemicals. Bridges two scientific cultures, providing an introduction to bioseparations for scientists with no background in engineering and for engineers with little grounding in biology. The authors supplement the ideas by simple worked examples, making the techniques of bioseparations easy to learn. Discusses removal of insolubles, product isolation, purification and polishing.
Book Synopsis Process Scale Bioseparations for the Biopharmaceutical Industry by : Abhinav A. Shukla
Download or read book Process Scale Bioseparations for the Biopharmaceutical Industry written by Abhinav A. Shukla and published by CRC Press. This book was released on 2006-07-07 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biopharmaceutical industry has become an increasingly important player in the global economy, and the success of these products depends on the development and implementation of cost-effective, robust and scaleable production processes. Bioseparations-also called downstream processing- can be a key source of competitive advantageto biopharmaceut
Book Synopsis Centrifugal Separations in Biotechnology by : Wallace Woon-Fong Leung
Download or read book Centrifugal Separations in Biotechnology written by Wallace Woon-Fong Leung and published by Butterworth-Heinemann. This book was released on 2020-03-13 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Centrifugal Separations in Biotechnology, Second Edition, is the only book on the market devoted to centrifugal separation in biotechnology. Key topics covered include a full introduction to centrifugation, sedimentation and separation; detailed coverage of centrifuge types, including batch and semi-batch centrifuges, disk-stack and tubular decanter centrifuges; methods for increasing solids concentration; laboratory and pilot testing of centrifuges; selection and sizing centrifuges; scale-up of equipment, performance prediction and analysis of test results using numerical simulation. Centrifugal Separations in Biotechnology, Second Edition, provides guidance on troubleshooting and optimizing centrifuges, and then goes on to explore the commercial applications of centrifuges in biotechnology. It gives detailed process information and data to assist in the development of particular processes from existing systems. It is of value to professionals in the chemical, bioprocess, and biotech sectors, and all those concerned with bioseparation, bioprocessing, unit-operations and process engineering. Provides a comprehensive guide to centrifuges, their optimal development, and their operation in the biotechnology industry Updated throughout based on developments in industrial applications and advances in our understanding of centrifugal separations in biotechnology Discusses applications for the separation of proteins, DNA, mitochondria, ribosomes, lysosomes and other cellular elements Includes new sections on use of optimal polymer dosage in waste treatment, new centrifuge designs for applications in algae processing, biopharma, and more
Download or read book Bioseparations written by Paul A. Belter and published by Wiley-Interscience. This book was released on 1988-02-22 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a concise introduction to the separation and purification of biochemicals. Bridges two scientific cultures, providing an introduction to bioseparations for scientists with no background in engineering and for engineers with little grounding in biology. The authors supplement the ideas by simple worked examples, making the techniques of bioseparations easy to learn. Discusses removal of insolubles, product isolation, purification and polishing.
Book Synopsis Engineering Principles in Biotechnology by : Wei-Shou Hu
Download or read book Engineering Principles in Biotechnology written by Wei-Shou Hu and published by John Wiley & Sons. This book was released on 2017-11-13 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a short introduction to the engineering principles of harnessing the vast potential of microorganisms, and animal and plant cells in making biochemical products. It was written for scientists who have no background in engineering, and for engineers with minimal background in biology. The overall subject dealt with is process. But the coverage goes beyond the process of biomanufacturing in the bioreactor, and extends to the factory of cell’s biosynthetic machinery. Starting with an overview of biotechnology and organism, engineers are eased into biochemical reactions and life scientists are exposed to the technology of production using cells. Subsequent chapters allow engineers to be acquainted with biochemical pathways, while life scientist learn about stoichiometric and kinetic principles of reactions and cell growth. This leads to the coverage of reactors, oxygen transfer and scale up. Following three chapters on biomanufacturing of current and future importance, i.e. cell culture, stem cells and synthetic biology, the topic switches to product purification, first with a conceptual coverage of operations used in bioseparation, and then a more detailed analysis to provide a conceptual understanding of chromatography, the modern workhorse of bioseparation. Drawing on principles from engineering and life sciences, this book is for practitioners in biotechnology and bioengineering. The author has used the book for a course for advanced students in both engineering and life sciences. To this end, problems are provided at the end of each chapter.
Book Synopsis Principles of Bioseparations Engineering by : Raja Ghosh
Download or read book Principles of Bioseparations Engineering written by Raja Ghosh and published by World Scientific Publishing Company. This book was released on 2006-10-23 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioseparations engineering deals with the scientific and engineering principles involved in large-scale separation and purification of biological products. It is a key component of most chemical engineering/biotechnology/bioprocess engineering programmes. This book discusses the underlying principles of bioseparations engineering written from the perspective of an undergraduate course. It covers membrane based bioseparations in much more detail than some of the other books on bioseparations engineering. Based largely on the lecture notes the author developed to teach the course, this book is especially suitable for use as an undergraduate level textbook, as most other textbooks are targeted at graduate students.
Book Synopsis Bioseparation Engineering by : I. Endo
Download or read book Bioseparation Engineering written by I. Endo and published by Elsevier. This book was released on 2000-03-17 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bioseparation engineering of today includes downstream process engineering such as waste water, material and gas treatment. Taking this tendency into account, bioseparation engineers gathered in Japan as a special research group under the main theme of "Recovery and Recycle of Resources to Protect the Global Environment". The scope of this book is based on the conference, and deals not only with recent advances in bioseparation engineering in a narrow sence, but also the environmental engineering which includes waste water treatment and bioremediation. The contributors of this book cover many disciplines such as chemical engineering, analytical chemistry, biochemistry, and microbiology. Bioseparation Engineering will stimulate young engineers and scientists who will develop bioseparation engineering further in the 21st century, and contribute to a world-wide attention to the global environment
Book Synopsis Liquid Biphasic System by : Pau Loke Show
Download or read book Liquid Biphasic System written by Pau Loke Show and published by Elsevier. This book was released on 2020-11-28 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Downstream bioprocesses have a significant role to play in the creation of a sustainable bio-based economy, enabling the creation of new products and systems from the more sustainable bioprocessing of natural products. Liquid Biphasic System: Fundamentals, Methods, and Applications in Bioseparation Technology explores in detail the fundamental processes and applications of this new separation system, aiding understanding of the basic principles of the technique and offering constructive criticisms on the latest findings. Including coverage of the background, principles, mechanisms, and applications, Liquid Biphasic System addresses how to adapt the technology for the purification of useful compounds with greater cost efficiency and greener processing. It is essential reading for bioprocess engineers, biochemical engineers, biosystem engineers, chemists and microbiologists working in the fields of bioprocessing. Researchers, scientists, and engineers concerned with the selection and evaluation of alternative bioseparation processes will find the book particularly useful. Provides information and examples of advanced separations in a single source Includes detailed descriptions of novel bioseparation systems Covers the latest technologies related to advanced liquid–liquid separation and their applications in various industries
Book Synopsis Neural Networks in Bioprocessing and Chemical Engineering by : D. R. Baughman
Download or read book Neural Networks in Bioprocessing and Chemical Engineering written by D. R. Baughman and published by Academic Press. This book was released on 2014-06-28 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural networks have received a great deal of attention among scientists and engineers. In chemical engineering, neural computing has moved from pioneering projects toward mainstream industrial applications. This book introduces the fundamental principles of neural computing, and is the first to focus on its practical applications in bioprocessing and chemical engineering. Examples, problems, and 10 detailed case studies demonstrate how to develop, train, and apply neural networks. A disk containing input data files for all illustrative examples, case studies, and practice problems provides the opportunity for hands-on experience. An important goal of the book is to help the student or practitioner learn and implement neural networks quickly and inexpensively using commercially available, PC-based software tools. Detailed network specifications and training procedures are included for all neural network examples discussed in the book. Each chapter contains an introduction, chapter summary, references to further reading, practice problems, and a section on nomenclature Includes a PC-compatible disk containing input data files for examples, case studies, and practice problems Presents 10 detailed case studies Contains an extensive glossary, explaining terminology used in neural network applications in science and engineering Provides examples, problems, and ten detailed case studies of neural computing applications, including: Process fault-diagnosis of a chemical reactor Leonard Kramer fault-classification problem Process fault-diagnosis for an unsteady-state continuous stirred-tank reactor system Classification of protein secondary-structure categories Quantitative prediction and regression analysis of complex chemical kinetics Software-based sensors for quantitative predictions of product compositions from flourescent spectra in bioprocessing Quality control and optimization of an autoclave curing process for manufacturing composite materials Predictive modeling of an experimental batch fermentation process Supervisory control of the Tennessee Eastman plantwide control problem Predictive modeling and optimal design of extractive bioseparation in aqueous two-phase systems
Download or read book BIOSPERATIONS written by B. SIVASANKAR and published by PHI Learning Pvt. Ltd.. This book was released on 2005-01-01 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This systematically organized and well-balanced book compresses within the covers of a single volume the theoretical principles and techniques involved in bio-separations, also called downstream processing. These techniques are derived from a range of subjects, for example, physical chemistry, analytical chemistry, bio-chemistry, biological science and chemical engineering. Organized in its 15 chapters, the text covers in the first few chapters topics related to chemical engineering unit operations such as filtration, centrifugation, adsorption, extraction and membrane separation as applied to bioseparations. The use of chromatography as practiced at laboratory as well as industrial scale operation and related techniques such as gel filtration, affinity and pseudoaffinity chromatography, ion-exchange chromatography, electrophoresis and related methods have been discussed. The important applications of these techniques have also been highlighted.
Book Synopsis Process Scale Purification of Antibodies by : Uwe Gottschalk
Download or read book Process Scale Purification of Antibodies written by Uwe Gottschalk and published by John Wiley & Sons. This book was released on 2017-03-07 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier technology experts to address the challenges of antibody purification. • Updates existing topics and adds new ones that include purification of antibodies produced in novel production systems, novel separation technologies, novel antibody formats and alternative scaffolds, and strategies for ton-scale manufacturing • Presents new and updated discussions of different purification technologies, focusing on how they can address the capacity crunch in antibody purification • Emphasizes antibodies and innovative chromatography methods for processing
Book Synopsis The Science and Engineering of Granulation Processes by : Jim Litster
Download or read book The Science and Engineering of Granulation Processes written by Jim Litster and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book had its origins in a meeting between two (relatively) young particle technology researchers on Rehobeth Beach in Delaware in 1992 near the holiday house of Reg Davies (then Director of the Particle Science and Technology Research Center in Dupont). As we played in the sand, we shared an excitement for developments in particle technology, especially particle characterization, that would lead operations such as granulation to be placed on a sound scientific and engineering footing. The immediate outcome from this interaction was the development of new industry short courses in granulation and related topics which we taught together both in Australia and North America. This book follows closely the structure and approaches developed in these courses, particularly the emphasis on particle design in granulation, where the impact of both formulation properties and process variables on product attributes needs to be understood and quantified. The book has been a long time in the making. We have been actively preparing the book for at least five years. Although the chapters have relatively good bibliographies, this book is not a review of the field. Rather it is an attempt by the authors to present a comprehensive engineering approach to granulator design, scale up and operation. It is exciting for us to see the explosion of research interest around the world in this area in the last five to seven years. Some of the most recent work will have to find its way into the second edition.