Biopharmaceutics of Ocular Drug Delivery

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Author :
Publisher : CRC Press
ISBN 13 : 1000696855
Total Pages : 230 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Biopharmaceutics of Ocular Drug Delivery by : Peter Edman

Download or read book Biopharmaceutics of Ocular Drug Delivery written by Peter Edman and published by CRC Press. This book was released on 2019-08-15 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: A significant new book on drug delivery to the eye Biopharmaceutics of Ocular Drug Delivery examines the current physiological, anatomical, pharmaceutical/technological, and biopharmaceutical knowledge on ocular drug delivery. Leading ophthalmic researchers cover topics such as the formulation and usage of ophthalmic solutions and suspensions, the influence of surfactants and preservatives on ocular drug absorption, and new techniques that include bioadhesion and the use of hyaluronic acid as an ophthalmic vehicle. Promising research on new delivery systems for improved drug therapy is highlighted, including new pharmaceutical vehicles, inserts, liposomes, nanoparticles, and prodrugs. Biopharmaceutics of Ocular Drug Delivery is one of the few books available on drug delivery to the eye and will be an important reference for ophthalmologists, pharmacologists, pharmaceutical researchers, and other scientists interested in the topic.

Ophthalmic Drug Delivery

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1475741758
Total Pages : 193 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Ophthalmic Drug Delivery by : M.F. Saettone

Download or read book Ophthalmic Drug Delivery written by M.F. Saettone and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the proceedings of the International Symposium on Ophthalmie Drug Delivery, which was held in Pisa in October 1986. Topical ophthalmic therapy is a matter of interest to specialists from different fields (medical, pharmaceutical, chemical, technological, etc.), who, unfortunately, have a tendency to meet separately, thus limiting a diffusion of knowledge, ideas and experience that would greatly favour the overall pro gress in this area of research. The Symposium, for the first time in Europe, provided the opportunity for specialists from different disciplines and from different countfies to meet, to discuss and to share their experience. This multidisciplinary approach is reflected in the wide variety of topics that appear in the book. The papers are aimed at reviewing many of the complex, interrelated, medical pharmaceutical and technological facets of topical ophthalmic therapy. lt is our hope that they may stimulate further thought in this fascinating field, and may provide possible guidelines for future research. The editors wish to express their appreciation to the sponsors of the Symposium: Fidia Research Laboratories, whose generosity permitted the meeting tobe held, and the ltalian National Research Council (CNR, Progetto Finalizzato Chimica Fine e Secondaria) who gave its scientific tutorship. Thanks are also due to the other Symposium contributors, ACRAF SpA, Rome, and Allergan Italia SpA, Rome. The assistance, support and coopera tion given before, during and after the Symposium by Dr. Patrizia Chetoni, Dr. Maria Tilde Torracca and Dr. Elena Parolini arealso gratefully acknowledged.

BioPharmaceutics of Ocular Drug Delivery

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Author :
Publisher : CRC-Press
ISBN 13 : 9780849372964
Total Pages : 224 pages
Book Rating : 4.3/5 (729 download)

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Book Synopsis BioPharmaceutics of Ocular Drug Delivery by : Peter Edman

Download or read book BioPharmaceutics of Ocular Drug Delivery written by Peter Edman and published by CRC-Press. This book was released on 1992-11-18 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: A significant new book on drug delivery to the eye Biopharmaceutics of Ocular Drug Delivery examines the current physiological, anatomical, pharmaceutical/technological, and biopharmaceutical knowledge on ocular drug delivery. Leading ophthalmic researchers cover topics such as the formulation and usage of ophthalmic solutions and suspensions, the influence of surfactants and preservatives on ocular drug absorption, and new techniques that include bioadhesion and the use of hyaluronic acid as an ophthalmic vehicle. Promising research on new delivery systems for improved drug therapy is highlighted, including new pharmaceutical vehicles, inserts, liposomes, nanoparticles, and prodrugs. Biopharmaceutics of Ocular Drug Delivery is one of the few books available on drug delivery to the eye and will be an important reference for ophthalmologists, pharmacologists, pharmaceutical researchers, and other scientists interested in the topic.

Treatise on Ocular Drug Delivery

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 1608051757
Total Pages : 301 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Treatise on Ocular Drug Delivery by : Ashim K. Mitra

Download or read book Treatise on Ocular Drug Delivery written by Ashim K. Mitra and published by Bentham Science Publishers. This book was released on 2013-06-26 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: A multidisciplinary approach is increasingly being adapted by the Pharmaceutical industry to tackle several challenges in developing efficacious treatment solutions. The field of Ophthalmology is no less different. Treatise on Ocular Drug Delivery is a unique collection of information put together by various experts in the field. One of the major goals behind this volume is to link clinical information with the current strategies employed in ocular drug delivery. This monograph covers a range of topics on ocular pharmacology. Chapters in the e-book cover several aspects of drug delivery research such as the biochemical background of specific eye diseases, challenges for ocular drug delivery, the role of influx and efflux transporters, novel drug delivery systems, pharmacokinetics, regulatory aspects, and patenting opportunities for researchers. This E-Book would serve as a suitable reference for pharmacy graduates, medical students, professional scientists and ophthalmic clinicians in academic and industrial laboratories.

Update on Polymers for Ocular Drug Delivery

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Author :
Publisher : Smithers Rapra
ISBN 13 : 1847355641
Total Pages : 210 pages
Book Rating : 4.8/5 (473 download)

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Book Synopsis Update on Polymers for Ocular Drug Delivery by : Atish S Mundada

Download or read book Update on Polymers for Ocular Drug Delivery written by Atish S Mundada and published by Smithers Rapra. This book was released on 2011-12-20 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye is the most easily accessible site for topical administration of a medication. Drugs are commonly applied to the eye for localised action on the surface or in the interior of the eye. A major problem in ocular therapeutics is the attainment of an optimal drug concentration at the site of action. Poor bioavailability of drugs from ocular dosage forms is mainly due to the precorneal loss factors which include tear dynamics, non-productive absorption, transient residence time in the cul-de-sac, and the relative impermeability of the corneal epithelial membrane. Due to these physiological and anatomical constraints only a small fraction of the drug, effectively 1% or even less of the instilled dose is ocularly absorbed. The effective dose of medication administered ophthalmically may be altered by increasing the retention time of medication in contact with the surface of the eye. To date, Pharmaceutical Technologists have tried to develop different novel formulations like gel, ocular inserts, collagen shields, implants, liposomes, nanoparticles, penetration enhancers and in-situ gelling systems, in order to increase the bioavailability and duration of the therapeutic action of ocular drugs and polymers plays an important role in all these approaches. This book provides detailed information regarding all such polymers which have been used and shown to be excellent in improving the bioavailability of ocular drugs.

Ocular Drug Delivery: Advances, Challenges and Applications

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Author :
Publisher : Springer
ISBN 13 : 3319476912
Total Pages : 185 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Ocular Drug Delivery: Advances, Challenges and Applications by : Richard T. Addo

Download or read book Ocular Drug Delivery: Advances, Challenges and Applications written by Richard T. Addo and published by Springer. This book was released on 2016-11-16 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye. Therefore, ocular drug delivery has been a major challenge to drug delivery researchers. There are on-going studies, in search of treatment especially for the diseases affecting the posterior segment of the eye. This book gives and overview of the background of ocular drug delivery and is unique for pharmacists, medical practitioners, students and drug delivery researchers.

Drug Product Development for the Back of the Eye

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441999205
Total Pages : 596 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Drug Product Development for the Back of the Eye by : Uday B. Kompella

Download or read book Drug Product Development for the Back of the Eye written by Uday B. Kompella and published by Springer Science & Business Media. This book was released on 2011-08-03 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and implant dosage forms Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering.

Ocular Drug Delivery Systems

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Author :
Publisher : CRC Press
ISBN 13 : 1439848009
Total Pages : 477 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Ocular Drug Delivery Systems by : Deepak Thassu

Download or read book Ocular Drug Delivery Systems written by Deepak Thassu and published by CRC Press. This book was released on 2012-10-02 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug discovery for ocular diseases has taken great strides in the last two decades. From cornea to choroid, new drugs have been formulated to address a great variety of ocular diseases. Yet without good drug delivery systems, these drugs are less effective than they might be or could even cause serious side effects. Ocular Drug Delivery Systems: Barriers and Application of Nanoparticulate Systems presents research on the development of currently marketed devices and recent trends in the topical delivery of drugs to the posterior of the eye. With contributions from leading pharmaceutical researchers and industry experts, eye researchers, surgeons, pharmacologists from academia, the National Eye Institute, and leading ophthalmic companies such as Pfizer, Allergan, and Novartis, the book presents the state of the art in the use of nanoparticles in ocular drug delivery systems and also sets the stage for future developments. This volume provides both a current evaluation and a future roadmap for developments in ocular drug delivery. The subjects range from biological needs to material challenges and finally to clinical applications for improving drug delivery for conditions where treatments already exist. It also explores areas where effective drugs may be currently available but yet need a safe, efficient, and efficacious delivery vehicle.

Ocular Theraputics and Drug Delivery

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Publisher : CRC Press
ISBN 13 : 9781566762137
Total Pages : 618 pages
Book Rating : 4.7/5 (621 download)

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Book Synopsis Ocular Theraputics and Drug Delivery by : Indra K. Reddy

Download or read book Ocular Theraputics and Drug Delivery written by Indra K. Reddy and published by CRC Press. This book was released on 1995-12-12 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since ocular therapeutics and drug delivery is a subject of interest to specialists from various disciplines such as chemical, biochemical, medical, pharmaceutical, and toxicological, it truly presents a unique situation requiring a multi-disciplinary approach in understanding and addressing various problems. Yet we see that scientists associated with these areas are working, by and large, independently of one another, thus limiting dissemination of knowledge, experience and ideas that would greatly enhance the overall progress in this area of research. Regrettably, the information currently available in ocular therapeutics and drug delivery, though extensive, is still fragmented into various disciplines making meaningful synthesis difficult. Several books are available that cover one or two aspects of the multi-disciplinary fields on an individual basis; however, none is available that covers all of them. The chapters contained in this book are specific to various interrelated areas of ocular therapeutics and drug delivery and are written by acknowledged experts from both academia and industry. The book itself is divided into five parts, namely: (I) overview,basic principles, and methodology; (II) pathopharmacology and clinical applications; (III) chemical/ biochemical approaches to ocular drug delivery; (IV) formulation and drug delivery considerations; and (V) industrial and regulatory considerations. Individual chapters in each section, apart from presenting a concise text, entail an extensive listing of references.

Textbook on Clinical Ocular Pharmacology & Therapeutics

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Author :
Publisher : JP Medical Ltd
ISBN 13 : 9351523411
Total Pages : 360 pages
Book Rating : 4.3/5 (515 download)

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Book Synopsis Textbook on Clinical Ocular Pharmacology & Therapeutics by : Renu Agarwal

Download or read book Textbook on Clinical Ocular Pharmacology & Therapeutics written by Renu Agarwal and published by JP Medical Ltd. This book was released on 2014-09-30 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide to ocular pharmacology for trainees and practising ophthalmologists. Beginning with the basic physiological aspects of ocular pharmacology and ophthalmic drug administration, the following sections discuss different types of drugs used in the treatment of eye disease. The final sections examine contact lens care systems, nutritional supplements and adverse effects of systematically administered drugs into the eye. This useful, quick reference text is highly illustrated with more than 145 images and tables. Key points Comprehensive guide to ocular pharmacology for trainees and practising ophthalmologists Covers different drugs for treatment of eye diseases Includes section on adverse effects of systematically administered drugs Highly illustrated with more than 145 images and tables

Ocular Therapeutics

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Publisher : JAYPEE BROTHERS PUBLISHERS
ISBN 13 : 9350907631
Total Pages : 1096 pages
Book Rating : 4.3/5 (59 download)

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Book Synopsis Ocular Therapeutics by : Ashok Garg

Download or read book Ocular Therapeutics written by Ashok Garg and published by JAYPEE BROTHERS PUBLISHERS. This book was released on 2013-12-15 with total page 1096 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this book Ocular Therapeutics has been completely updated with addition of all new ocular drugs and delivery systems in every group of medicine used in ophthalmic disease and surgeries. Sixty-nine chapters of this line have been grouped as preliminary section, Applied Ocular Therapeutics and Recent Advances. In this comprehensive book leading International Ocular Drug Experts have shared their experiences and evidence-based knowledge in the form of chapters. It shall serve as ready reference for all ophthalmologists world-wide who are engaged in eradication of global blind.

Clinical Ocular Pharmacology

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0750675764
Total Pages : 816 pages
Book Rating : 4.7/5 (56 download)

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Book Synopsis Clinical Ocular Pharmacology by : Jimmy D. Bartlett

Download or read book Clinical Ocular Pharmacology written by Jimmy D. Bartlett and published by Elsevier Health Sciences. This book was released on 2007-11-12 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in the field, this comprehensive resource offers valuable information on the practical uses of drugs in primary eye care. Discussions of the pharmacology of ocular drugs such as anti-infective agents, anti-glaucoma drugs, and anti-allergy drugs lead to more in-depth information on ocular drugs used to treat a variety of disorders, including diseases of the eyelids, corneal diseases, ocular infections, and glaucoma. The book also covers ocular toxicology, focusing on drug interactions, ocular effects of systemic drugs, and life-threatening systemic emergencies. A logical organization makes it easy to find essential information. Complete coverage of the basic fundamentals of pharmacology such as ocular drug delivery and ocular drug formulations. Comprehensive reviews of the pharmacology of specific classes of agents such as the cycloplegics, antiglaucoma drugs, anti-inflammatory drugs, ocular irrigating solutions, and contact lens care products. In-depth information on ocular drugs used in clinical practice, including chapters on drugs used to treat eyelid disorders, lacrimal diseases, conjunctiva diseases, corneal diseases, allergies, uveitis, postoperative cataract, retinal diseases, and glaucoma. Coverage of ocular toxicology, including drug interactions, ocular effects of systemic drugs, and life-threatening systemic emergencies. Completely revised and updated content that reflects the latest advances in pharmacology. Updated information on post-operative drugs, including LASIK follow up medications. Expanded coverage in the chapters on Anti-infective Drugs, Anti-allergy Drugs and Decongestants, and Lubricants and Other Preparations of Ocular Surface Disease that includes the latest advancements in antibiotics and medications used to treat allergies and dry eye. A dosage quick reference guide on the inside front cover for quick and easy access. Information on the use of herbal medications.

Ophthalmic Product Development

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Author :
Publisher : Springer Nature
ISBN 13 : 3030763676
Total Pages : 650 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Ophthalmic Product Development by : Seshadri Neervannan

Download or read book Ophthalmic Product Development written by Seshadri Neervannan and published by Springer Nature. This book was released on 2022-03-11 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive textbook addressing the unique aspects of drug development for ophthalmic use. Beginning with a perspective on anatomy and physiology of the eye, the book provides a critical appraisal of principles that underlie ocular drug product development. The coverage encompasses topical and intraocular formulations, small molecules and biologics (including protein and gene therapies), conventional formulations (including solutions, suspensions, and emulsions), novel formulations (including nanoparticles, microparticles, and hydrogels), devices, and specialty products. Critical elements such as pharmacokinetics, influence of formulation technologies and ingredients, as well as impact of disease conditions on products development are addressed. Products intended for both the front and the back of the eye are discussed with an eye towards future advances. @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;}@font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-469750017 -1073732485 9 0 511 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-ansi-language:EN-US; mso-fareast-language:EN-US;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:EN-US; mso-fareast-language:EN-US;}div.WordSection1 {page:WordSection1;}

Ocular Drug Delivery Systems

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Author :
Publisher : GRIN Verlag
ISBN 13 : 3346902722
Total Pages : 46 pages
Book Rating : 4.3/5 (469 download)

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Book Synopsis Ocular Drug Delivery Systems by : Manish Kumar

Download or read book Ocular Drug Delivery Systems written by Manish Kumar and published by GRIN Verlag. This book was released on 2023-07-07 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: Academic Paper from the year 2023 in the subject Medicine - Pharmacology, Pharmacy, , course: M.Pharmacy, language: English, abstract: Ocular drug delivery plays a vital role in the treatment of various eye diseases and conditions. The unique anatomical and physiological characteristics of the eye pose significant challenges for effective drug delivery. Over the years, extensive research efforts have been dedicated to developing innovative strategies and formulations to overcome these challenges and improve therapeutic outcomes. This review provides an overview of recent advances in ocular drug delivery, highlighting the key challenges faced and discussing the potential future directions in this field. The first section of the review focuses on the barriers to ocular drug delivery, including the tear film, cornea, conjunctiva, and blood-ocular barriers. These barriers limit the bioavailability and efficacy of drugs administered to the eye. Strategies to bypass or overcome these barriers, such as the use of penetration enhancers, nanoparticles, and prodrug approaches, are discussed. The second section explores various ocular drug delivery systems, including eye drops, ophthalmic gels, ocular inserts, and contact lens-based delivery systems. Each system is examined in terms of its advantages, limitations, and recent advancements. Special attention is given to sustained drug release systems that aim to prolong drug residence time on the ocular surface and improve patient compliance. Next, the review delves into the role of nanotechnology in ocular drug delivery. Nanoparticles, liposomes, and nanomicelles have shown promise in improving drug solubility, stability, and ocular bioavailability. The use of novel nanomaterials and their surface modifications for targeted drug delivery to specific ocular tissues is also discussed. Furthermore, the review highlights emerging techniques in ocular drug delivery, such as microneedles, hydrogels, and gene therapy-based approaches. These technologies offer exciting prospects for precise and personalized treatment of ocular diseases. Finally, the review concludes by discussing the regulatory considerations, safety aspects, and clinical translation of ocular drug delivery systems. The importance of collaboration between researchers, clinicians, and regulatory bodies in advancing this field is emphasized.

Ophthalmic Drug Delivery Systems

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Author :
Publisher : CRC Press
ISBN 13 : 9780367446765
Total Pages : 847 pages
Book Rating : 4.4/5 (467 download)

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Book Synopsis Ophthalmic Drug Delivery Systems by : Ashim K. Mitra

Download or read book Ophthalmic Drug Delivery Systems written by Ashim K. Mitra and published by CRC Press. This book was released on 2019-12-02 with total page 847 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery.

Intraocular Drug Delivery

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Author :
Publisher : CRC Press
ISBN 13 : 1420016504
Total Pages : 385 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Intraocular Drug Delivery by : Glenn J. Jaffe

Download or read book Intraocular Drug Delivery written by Glenn J. Jaffe and published by CRC Press. This book was released on 2006-03-13 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference studies the most recent advances in the development of ocular drug delivery systems. Covering methods to treat or prevent ocular inflammation, retinal vascular disease, retinal degeneration, and proliferative eye disease, this source covers breakthroughs in the management of endophthalmitis, uveitis, diabetic macular edema, and age-r

Drug Product Development for the Back of the Eye

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Author :
Publisher : Springer
ISBN 13 : 9781441999214
Total Pages : 592 pages
Book Rating : 4.9/5 (992 download)

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Book Synopsis Drug Product Development for the Back of the Eye by : Uday B. Kompella

Download or read book Drug Product Development for the Back of the Eye written by Uday B. Kompella and published by Springer. This book was released on 2011-08-09 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and implant dosage forms Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering.