Biomedical Engineering: Frontier Research and Converging Technologies

Download Biomedical Engineering: Frontier Research and Converging Technologies PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3319218131
Total Pages : 511 pages
Book Rating : 4.3/5 (192 download)

DOWNLOAD NOW!


Book Synopsis Biomedical Engineering: Frontier Research and Converging Technologies by : Hanjoong Jo

Download or read book Biomedical Engineering: Frontier Research and Converging Technologies written by Hanjoong Jo and published by Springer. This book was released on 2015-07-23 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with an integrative overview of the latest research and developments in the broad field of biomedical engineering. Each of the chapters offers a timely review written by leading biomedical engineers and aims at showing how the convergence of scientific and engineering fields with medicine has created a new basis for practically solving problems concerning human health, wellbeing and disease. While some of the latest frontiers of biomedicine, such as neuroscience and regenerative medicine, are becoming increasingly dependent on new ideas and tools from other disciplines, the paradigm shift caused by technological innovations in the fields of information science, nanotechnology, and robotics is opening new opportunities in healthcare, besides dramatically changing the ways we actually practice science. At the same time, a new generation of engineers, fluent in many different scientific “languages,” is creating entirely new fields of research that approach the “old” questions from a new and holistic angle. The book reports on the scientific revolutions in the field of biomedicine by describing the latest technologies and findings developed at the interface between science and engineering. It addresses students, fellows, and faculty and industry investigators searching for new challenges in the broad biomedical engineering fields.

Biomedical Engineering: Concepts, Methodologies, Tools, and Applications

Download Biomedical Engineering: Concepts, Methodologies, Tools, and Applications PDF Online Free

Author :
Publisher : IGI Global
ISBN 13 : 1522531599
Total Pages : 1463 pages
Book Rating : 4.5/5 (225 download)

DOWNLOAD NOW!


Book Synopsis Biomedical Engineering: Concepts, Methodologies, Tools, and Applications by : Management Association, Information Resources

Download or read book Biomedical Engineering: Concepts, Methodologies, Tools, and Applications written by Management Association, Information Resources and published by IGI Global. This book was released on 2017-07-13 with total page 1463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technological tools and computational techniques have enhanced the healthcare industry. These advancements have led to significant progress and novel opportunities for biomedical engineering. Biomedical Engineering: Concepts, Methodologies, Tools, and Applications is an authoritative reference source for emerging scholarly research on trends, techniques, and future directions in the field of biomedical engineering technologies. Highlighting a comprehensive range of topics such as nanotechnology, biomaterials, and robotics, this multi-volume book is ideally designed for medical practitioners, professionals, students, engineers, and researchers interested in the latest developments in biomedical technology.

Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine

Download Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 1315341026
Total Pages : 847 pages
Book Rating : 4.3/5 (153 download)

DOWNLOAD NOW!


Book Synopsis Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine by : Gilson Khang

Download or read book Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine written by Gilson Khang and published by CRC Press. This book was released on 2017-06-26 with total page 847 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of patients suffer from end-stage organ failure or tissue loss annually, and the only solution might be organ and/or tissue transplantation. To avoid poor biocompatibility–related problems and donor organ shortage, however, around 20 years ago a new, hybridized method combining cells and biomaterials was introduced as an alternative to whole-organ and tissue transplantation for diseased, failing, or malfunctioning organs—regenerative medicine and tissue engineering. This handbook focuses on all aspects of intelligent scaffolds, from basic science to industry to clinical applications. Its 10 parts, illustrated throughout with excellent figures, cover stem cell engineering research, drug delivery systems, nanomaterials and nanodevices, and novel and natural biomaterials. The book can be used by advanced undergraduate- and graduate-level students of stem cell and tissue engineering and researchers in macromolecular science, ceramics, metals for biomaterials, nanotechnology, chemistry, biology, and medicine, especially those interested in tissue engineering, stem cell engineering, and regenerative medicine.

Medical Robotics and AI-Assisted Diagnostics for a High-Tech Healthcare Industry

Download Medical Robotics and AI-Assisted Diagnostics for a High-Tech Healthcare Industry PDF Online Free

Author :
Publisher : IGI Global
ISBN 13 :
Total Pages : 479 pages
Book Rating : 4.3/5 (693 download)

DOWNLOAD NOW!


Book Synopsis Medical Robotics and AI-Assisted Diagnostics for a High-Tech Healthcare Industry by : Khang, Alex

Download or read book Medical Robotics and AI-Assisted Diagnostics for a High-Tech Healthcare Industry written by Khang, Alex and published by IGI Global. This book was released on 2024-03-04 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: While ultra-high field strength diagnosis technologies and artificial intelligence have propelled medicine imaging towards microstructure analysis and precise medicine, persistent challenges remain. These range from long scanning times to motion sensitivity and issues with imaging quality for certain types of tissue. Medical Robotics and AI-Assisted Diagnostics for a High-Tech Healthcare Industry summarizes emerging techniques, outlines clinical applications, and confronts the challenges head-on, proposing avenues for further research. It explores emerging techniques such as human-like robotics, medical Internet of Things (IoT), low-cost CT scanners, portable MRI devices, and breakthroughs in diagnosis technologies like zero echo time (ZTM) and compressed sensing volume interpolation breath-holding test sequences (CS-VIBE). This book provides an overview of the current state of medical imaging and clinical diagnosis applications, then expands into a roadmap for the future, envisioning the seamless integration of medical robotics and AI-assisted applications in the high-tech healthcare industry. As the influence of artificial intelligence continues to grow, the book serves as a clarion call for collaborative efforts, increased research, and unified strategies to navigate the challenges and harness the opportunities presented by the high-tech medical industry. This book is ideal for medical analysts, healthcare scientists, biotechnology analysts, scholars, researchers, academics, professionals, engineers, and students worldwide.

Biomedical Engineering for Global Health

Download Biomedical Engineering for Global Health PDF Online Free

Author :
Publisher : Cambridge University Press
ISBN 13 : 0521877970
Total Pages : 417 pages
Book Rating : 4.5/5 (218 download)

DOWNLOAD NOW!


Book Synopsis Biomedical Engineering for Global Health by : Rebecca Richards-Kortum

Download or read book Biomedical Engineering for Global Health written by Rebecca Richards-Kortum and published by Cambridge University Press. This book was released on 2010 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Can technology and innovation transform world health? Connecting undergraduate students with global problems, Rebecca Richards-Kortum examines the interplay between biomedical technology design and the medical, regulatory, economic, social and ethical issues surrounding global health. Driven by case studies, including cancer screening, imaging technologies, implantable devices and vaccines, students learn how the complexities and variation across the globe affect the design of devices and therapies. A wealth of learning features, including classroom activities, project assignments, homework problems and weblinks within the book and online, provide a full teaching package. For visionary general science and biomedical engineering courses, this book will inspire students to engage in solving global issues that face us all.

Data Analytics in Medicine: Concepts, Methodologies, Tools, and Applications

Download Data Analytics in Medicine: Concepts, Methodologies, Tools, and Applications PDF Online Free

Author :
Publisher : IGI Global
ISBN 13 : 1799812057
Total Pages : 2071 pages
Book Rating : 4.7/5 (998 download)

DOWNLOAD NOW!


Book Synopsis Data Analytics in Medicine: Concepts, Methodologies, Tools, and Applications by : Management Association, Information Resources

Download or read book Data Analytics in Medicine: Concepts, Methodologies, Tools, and Applications written by Management Association, Information Resources and published by IGI Global. This book was released on 2019-12-06 with total page 2071 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advancements in data science have created opportunities to sort, manage, and analyze large amounts of data more effectively and efficiently. Applying these new technologies to the healthcare industry, which has vast quantities of patient and medical data and is increasingly becoming more data-reliant, is crucial for refining medical practices and patient care. Data Analytics in Medicine: Concepts, Methodologies, Tools, and Applications is a vital reference source that examines practical applications of healthcare analytics for improved patient care, resource allocation, and medical performance, as well as for diagnosing, predicting, and identifying at-risk populations. Highlighting a range of topics such as data security and privacy, health informatics, and predictive analytics, this multi-volume book is ideally designed for doctors, hospital administrators, nurses, medical professionals, IT specialists, computer engineers, information technologists, biomedical engineers, data-processing specialists, healthcare practitioners, academicians, and researchers interested in current research on the connections between data analytics in the field of medicine.

Intelligent Systems for Healthcare Management and Delivery

Download Intelligent Systems for Healthcare Management and Delivery PDF Online Free

Author :
Publisher : IGI Global
ISBN 13 : 1522570721
Total Pages : 377 pages
Book Rating : 4.5/5 (225 download)

DOWNLOAD NOW!


Book Synopsis Intelligent Systems for Healthcare Management and Delivery by : Bouchemal, Nardjes

Download or read book Intelligent Systems for Healthcare Management and Delivery written by Bouchemal, Nardjes and published by IGI Global. This book was released on 2018-12-07 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the growing use of new technologies and artificial intelligence (AI) applications, intelligent systems can be used to manage large amounts of existing data in healthcare domains. Having more intelligent methods for accessing data allows medical professionals to more efficiently identify the best medical practices and more concrete solutions for diagnosing and treating a multitude of rare diseases. Intelligent Systems for Healthcare Management and Delivery provides relevant and advanced methodological, technological, and scientific approaches related to the application of sophisticated exploitation of AI, as well as providing insight into the technologies and intelligent applications that have received growing attention in recent years such as medical imaging, EMR systems, and drug development assistance. This publication fosters a scientific debate for new healthcare intelligent systems and sophisticated approaches for enhanced healthcare services and is ideally designed for medical professionals, hospital staff, rehabilitation specialists, medical educators, and researchers.

Design, Development, and Integration of Reliable Electronic Healthcare Platforms

Download Design, Development, and Integration of Reliable Electronic Healthcare Platforms PDF Online Free

Author :
Publisher : IGI Global
ISBN 13 : 1522517251
Total Pages : 357 pages
Book Rating : 4.5/5 (225 download)

DOWNLOAD NOW!


Book Synopsis Design, Development, and Integration of Reliable Electronic Healthcare Platforms by : Moumtzoglou, Anastasius

Download or read book Design, Development, and Integration of Reliable Electronic Healthcare Platforms written by Moumtzoglou, Anastasius and published by IGI Global. This book was released on 2016-10-19 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advancements in technology have brought about a new era of medicinal practice; however, these new technological trends present both advantages and challenges to their utilization. Design, Development, and Integration of Reliable Electronic Healthcare Platforms is an authoritative reference work on the issues relating to the quality and safety of technology use in the medical realm. Featuring coverage on best practices, detailed analysis, and upcoming trends, this publication is essential for researchers, students and professionals seeking current research on the implementation of electronic technologies in healthcare.

Stem Cells in Clinical Practice and Tissue Engineering

Download Stem Cells in Clinical Practice and Tissue Engineering PDF Online Free

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1789230101
Total Pages : 353 pages
Book Rating : 4.7/5 (892 download)

DOWNLOAD NOW!


Book Synopsis Stem Cells in Clinical Practice and Tissue Engineering by : Rakesh Sharma

Download or read book Stem Cells in Clinical Practice and Tissue Engineering written by Rakesh Sharma and published by BoD – Books on Demand. This book was released on 2018-05-02 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters are arranged in the order of basic concepts of stem cell differentiation, clinical applications of pluripotent stem cells in skin, cardiac, bone, dental, obesity centers, followed by tissue engineering, new materials used, and overall evaluation with their permitted legal status.

Basic Science Methods for Clinical Researchers

Download Basic Science Methods for Clinical Researchers PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 012803078X
Total Pages : 382 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!


Book Synopsis Basic Science Methods for Clinical Researchers by : Morteza Jalali

Download or read book Basic Science Methods for Clinical Researchers written by Morteza Jalali and published by Academic Press. This book was released on 2017-03-31 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow’s clinician scientists and future leaders in discovery science. Serves as a helpful guide for clinical researchers who lack a conventional science background Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)

Robotic Systems: Concepts, Methodologies, Tools, and Applications

Download Robotic Systems: Concepts, Methodologies, Tools, and Applications PDF Online Free

Author :
Publisher : IGI Global
ISBN 13 : 1799817555
Total Pages : 2075 pages
Book Rating : 4.7/5 (998 download)

DOWNLOAD NOW!


Book Synopsis Robotic Systems: Concepts, Methodologies, Tools, and Applications by : Management Association, Information Resources

Download or read book Robotic Systems: Concepts, Methodologies, Tools, and Applications written by Management Association, Information Resources and published by IGI Global. This book was released on 2020-01-03 with total page 2075 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through expanded intelligence, the use of robotics has fundamentally transformed a variety of fields, including manufacturing, aerospace, medicine, social services, and agriculture. Continued research on robotic design is critical to solving various dynamic obstacles individuals, enterprises, and humanity at large face on a daily basis. Robotic Systems: Concepts, Methodologies, Tools, and Applications is a vital reference source that delves into the current issues, methodologies, and trends relating to advanced robotic technology in the modern world. Highlighting a range of topics such as mechatronics, cybernetics, and human-computer interaction, this multi-volume book is ideally designed for robotics engineers, mechanical engineers, robotics technicians, operators, software engineers, designers, programmers, industry professionals, researchers, students, academicians, and computer practitioners seeking current research on developing innovative ideas for intelligent and autonomous robotics systems.

Cardiac Cell Culture Technologies

Download Cardiac Cell Culture Technologies PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3319706853
Total Pages : 245 pages
Book Rating : 4.3/5 (197 download)

DOWNLOAD NOW!


Book Synopsis Cardiac Cell Culture Technologies by : Zbigniew Brzozka

Download or read book Cardiac Cell Culture Technologies written by Zbigniew Brzozka and published by Springer. This book was released on 2017-11-21 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to the biological background of heart functioning and analyzes the various materials and technologies used for the development of microfluidic systems dedicated to cell culture, with an emphasis on cardiac cells. The authors describe the characterization of microfluidic systems for cardiac cell culture and center their discussion of the use of stem cell stimulation based on four different types: electrical, biochemical, physical, and mechanical. This book is appropriate for researchers focused on on-chip technologies and heart studies, students in bioengineering and microengineering courses, and a variety of professionals, such as biotechnologists, biomedical engineers, and clinicians working in the cardiac diseases field.

Big Data Analytics and Computational Intelligence for Cybersecurity

Download Big Data Analytics and Computational Intelligence for Cybersecurity PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 303105752X
Total Pages : 336 pages
Book Rating : 4.0/5 (31 download)

DOWNLOAD NOW!


Book Synopsis Big Data Analytics and Computational Intelligence for Cybersecurity by : Mariya Ouaissa

Download or read book Big Data Analytics and Computational Intelligence for Cybersecurity written by Mariya Ouaissa and published by Springer Nature. This book was released on 2022-09-01 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a collection of state-of-the-art artificial intelligence and big data analytics approaches to cybersecurity intelligence. It illustrates the latest trends in AI/ML-based strategic defense mechanisms against malware, vulnerabilities, cyber threats, as well as proactive countermeasures. It also introduces other trending technologies, such as blockchain, SDN, and IoT, and discusses their possible impact on improving security. The book discusses the convergence of AI/ML and big data in cybersecurity by providing an overview of theoretical, practical, and simulation concepts of computational intelligence and big data analytics used in different approaches of security. It also displays solutions that will help analyze complex patterns in user data and ultimately improve productivity. This book can be a source for researchers, students, and practitioners interested in the fields of artificial intelligence, cybersecurity, data analytics, and recent trends of networks.

Robotics in Healthcare

Download Robotics in Healthcare PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030242307
Total Pages : 134 pages
Book Rating : 4.0/5 (32 download)

DOWNLOAD NOW!


Book Synopsis Robotics in Healthcare by : João Silva Sequeira

Download or read book Robotics in Healthcare written by João Silva Sequeira and published by Springer Nature. This book was released on 2020-02-17 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: The work is a collection of contributions resulting from R&D efforts originated from scientific projects involving academia, technological partners, and end-user institutions. The aim is to provide a comprehensive overview of robotics technology applied to Healthcare, and discuss the anticipation of upcoming challenges. The intersection of Robotics and Medicine includes socially and economically relevant areas, such as rehabilitation, therapy, and healthcare. Innovative usages of current robotics technologies are being somewhat stranded by concerns related to social dynamics. The examples covered in this volume show some of the potential societal benefits robotics can bring and how the robots are being integrated in social environments. Despite the aforementioned concerns, a fantastic range of possibilities is being opened. The current trend in social robotics adds to technology challenges and requires R&D to think about Robotics as an horizontal discipline, intersecting social and exact sciences. For example, robots that can act as if they have credible personalities (not necessarily similar to humans) living in social scenarios, eventually helping people. Also, robots can move inside the human body to retrieve information that otherwise is difficult to obtain. The decision autonomy of these robots raises a broad range of subjects though the immediate advantages of its use are evident. The book presents examples of robotics technologies tested in healthcare environments or realistically close to being deployed in the field and discusses the challenges involved. Chapter 1 provides a comprehensive overview of Healthcare robotics and points to realistically expectable developments in the near future. Chapter 2 describes the challenges deploying a social robot in the Pediatrics ward of an Oncological hospital for simple edutainment activities. Chapter 3 focuses on Human-Robot Interaction techniques and their role in social robotics. Chapter 4 focus on R&D efforts behind an endoscopic capsule robot. Chapter 5 addresses experiments in rehabilitation with orthotics and walker robots. These examples have deep social and economic relations with the Healthcare field, and, at the same time, are representative of the R&D efforts the robotics community is developing.

Cartilage: From Biology to Biofabrication

Download Cartilage: From Biology to Biofabrication PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 9819924529
Total Pages : 531 pages
Book Rating : 4.8/5 (199 download)

DOWNLOAD NOW!


Book Synopsis Cartilage: From Biology to Biofabrication by : Mohamadreza Baghaban Eslaminejad

Download or read book Cartilage: From Biology to Biofabrication written by Mohamadreza Baghaban Eslaminejad and published by Springer Nature. This book was released on 2023-07-11 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of cartilage structure, functions, and approaches for the regeneration of cartilage tissue. It reviews multiple signaling pathways that are involved in the growth and repair of cartilage tissue. The initial chapter of the book examines the etiology, diagnosis, and pathological features of various cartilage diseases. Subsequently, the book presents recent advances in biomaterial sciences, regenerative medicine, and fabrication technology for cartilage regeneration. It discusses hydrogels as a promising scaffold for cartilage tissue engineering, focusing on recapitulating microenvironments present during development or in adult tissue to induce the formation of cartilaginous constructs with biochemical and mechanical properties of native tissue. Lastly, it covers the applications of 3 D printing techniques for the fabrication of scaffolds for cartilage tissue regeneration for the production of biological implants capable of treating a range of conditions.

The Cambridge Handbook of Information Technology, Life Sciences and Human Rights

Download The Cambridge Handbook of Information Technology, Life Sciences and Human Rights PDF Online Free

Author :
Publisher : Cambridge University Press
ISBN 13 : 1108809391
Total Pages : 862 pages
Book Rating : 4.1/5 (88 download)

DOWNLOAD NOW!


Book Synopsis The Cambridge Handbook of Information Technology, Life Sciences and Human Rights by : Marcello Ienca

Download or read book The Cambridge Handbook of Information Technology, Life Sciences and Human Rights written by Marcello Ienca and published by Cambridge University Press. This book was released on 2022-05-26 with total page 862 pages. Available in PDF, EPUB and Kindle. Book excerpt: Debates on the human-rights implications of new and emerging technologies have been hampered by the lack of a comprehensive theoretical framework for the complex issues involved. This volume provides that framework, bringing a multidisciplinary and international perspective to the evolution of human rights in the digital and biotechnological era. It delves into the latest frontiers of technological innovation in the life sciences and information technology sectors, such as neurotechnology, robotics, genetic engineering, and artificial intelligence. Leading experts from the technological, medical, and social sciences as well as law, philosophy, and business share their extensive knowledge about the transformation of the rights framework in response to technological innovation. In addition to providing a comprehensive, interdisciplinary, and international state-of-the art descriptive analysis, the volume also offers policy recommendations to protect and promote human rights in the context of emerging socio-technological trends.

Handbook of Manufacturing Systems and Design

Download Handbook of Manufacturing Systems and Design PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 1000959864
Total Pages : 345 pages
Book Rating : 4.0/5 (9 download)

DOWNLOAD NOW!


Book Synopsis Handbook of Manufacturing Systems and Design by : Uzair Khaleeq uz Zaman

Download or read book Handbook of Manufacturing Systems and Design written by Uzair Khaleeq uz Zaman and published by CRC Press. This book was released on 2023-08-24 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of manufacturing systems, their role in product/process design, and their interconnection with an Industry 4.0 perspective, especially related to design, manufacturing, and operations. Handbook of Manufacturing Systems and Design: An Industry 4.0 Perspective provides the knowledge related to the theories and concepts of Industry 4.0. It focuses on the different types of manufacturing systems in Industry 4.0 along with associated design, and control strategies. It concentrates on the operations in Industry 4.0 with a particular focus on supply chain, logistics, risk management, and reverse engineering perspectives. Offering basic concepts and applications through to advanced topics, the handbook feeds into the goal of being a source of knowledge as well as a vehicle to explore the future possibilities of design, techniques, methods, and operations associated with Industry 4.0. Concepts with practical applications in the form of case studies are added to each chapter to round out the many attributes this handbook offers. This handbook targets students, engineers, managers, designers, and manufacturers, and will assist in their understanding of the core concepts of manufacturing systems in connection with Industry 4.0 and optimize alignment between supply and demand in real time for effective implementation of the design concepts.