Biomaterials And Devices For The Circulatory System

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Biomaterials and Devices for the Circulatory System

Author : Terence Gourlay
Publisher : Elsevier
ISBN 13 : 0857090550
Total Pages : 400 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Biomaterials and Devices for the Circulatory System by : Terence Gourlay

Download or read book Biomaterials and Devices for the Circulatory System written by Terence Gourlay and published by Elsevier. This book was released on 2010-10-28 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular disease is one of the leading causes of death in the world today. Thanks to major advances in circulatory biomaterials and medical devices over the past few decades, many complications of this prevalent disease can be managed with great success for prolonged periods. Biomaterials and devices for the circulatory system reviews the latest developments in this important field and how they can be used to improve the success and safety in this industry. Part one discusses physiological responses to biomaterials with chapters on tissue response, blood interface and biocompatibility. Part two then reviews clinical applications including developments in valve technology, percutaneous valve replacement, bypass technologies and cardiovascular stents. Part three covers future developments in the field with topics such as nanomedicine, cardiac restoration therapy, biosensor technology in the treatment of cardiovascular disease and vascular tissue engineering. With its distinguished editors and international team of contributors Biomaterials and devices for the circulatory system is a vital reference for those concerned with bioengineering, medical devices and clinicians within this critical field. Reviews the latest developments in this important field and how they can be used to improve success and safety in the industry Both current clinical advances as well as future innovation are assessed taking a progressive view of the role of biomaterials in medical applications An examination of the physiological responses to biomaterials features tissue responses to implanted materials and strategies to improve the biocompatibility of medical devices

Bioengineering and Biomaterials in Ventricular Assist Devices

Author : Eduardo Guy Perpétuo Bock
Publisher : CRC Press
ISBN 13 : 1000462854
Total Pages : 363 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Bioengineering and Biomaterials in Ventricular Assist Devices by : Eduardo Guy Perpétuo Bock

Download or read book Bioengineering and Biomaterials in Ventricular Assist Devices written by Eduardo Guy Perpétuo Bock and published by CRC Press. This book was released on 2021-10-07 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Often associated with artificial hearts, ventricular assist devices (VADs) are blood pumps that can provide circulatory assistance to the left ventricle, the right ventricle, or both. Bioengineering and Biomaterials in Ventricular Assist Devices reviews constructive details of VADs and the biomaterials used in their development and support. FEATURES Establishes an area of intersection between engineering and medicine Shows process development from mechanical design to automation and control Discusses biofunctional materials, tribology in ceramic biomaterials, biosensors, and surface engineering and blood This text is aimed at advanced students, researchers, and practicing engineers conducting work on VADs and will be of interest to a broad interdisciplinary group, including bioengineers, materials engineers, chemical engineers, mechanical engineers, and electrical engineers.

Characterization of Biomaterials

Author : Ming H. Wu
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128071052
Total Pages : 450 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Characterization of Biomaterials by : Ming H. Wu

Download or read book Characterization of Biomaterials written by Ming H. Wu and published by Elsevier Inc. Chapters. This book was released on 2013-03-12 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cardiovascular system consists of the heart and the vasculature. The physiology of the system is to circulate blood through the vasculature ensuring delivery of oxygen and vital nutrients to cells and organs in the body. Consequences of diseases disrupting normal cardiovascular function can be severe or fatal. Recent advancements in cardiovascular medicine have contributed significantly to improving life span and quality for patients by restoring normal cardiovascular function through the use of implantable devices. Examples of these cardiovascular implantable devices include endovascular stents, embolic protection devices and filters, closure devices, heart valve prostheses, cardiac rhythm management devices, such as pacemakers and defibrillators, and left ventricular assist devices. The main objective of this chapter is to provide an overview of device test methods commonly used in the development process from concept to commercialization of implantable cardiovascular devices. It is recognized that general device testing methodology and understanding for developing these cardiovascular devices can be extended to other devices as well as new product concepts under development. Developments of new medical devices are closely regulated by regulatory agencies. U.S. and international regulatory requirements for medical devices and drugs provide specific guidance for bench-top in vitro testing, in vivo animal study, clinical research, manufacturing, sterilization, and post-market surveillance for various device categories. Implantable cardiovascular devices generally fall within the Class II and Class III categories. Commercialization of these products in the United States requires FDA's Premarket Notifications (510Ks), Premarket Approvals (PMAs), or Exemptions. The design control element in the new product development procedure requires detailed documentation of design inputs and outputs as well as rational design verification through testing to ensure device functions and safety. Notably, implantable cardiovascular devices are subjected to very high safety expectation. The inability to perform periodic inspection and repair after device implantation also means that the statistical reliability and safety for these devices must be well established and verified prior to clinical uses. To facilitate discussions, a brief overview of the cardiovascular anatomy and physiology is provided in the beginning of this chapter. Following this overview are sections reviewing exemplary implantable devices used for treating various cardiovascular disorders. The majority of this chapter is then devoted to descriptions of necessary engineering characterizations and design verification test methods most relevant to developing cardiovascular devices for commercialization. Particular emphasis is placed on the attributes that are significantly affected by the biomaterials used in the designs. These include physical properties, such as the transformation temperatures for nitinol self-expanding devices, mechanical properties, structure integrity and durability, corrosion risk assessment as well as functional testing. In addition, biocompatibility testing refers to a battery of testing used to evaluate the biological reaction of the human body to the implanted device. There is a well-recognized ISO standard that governs the specific test protocol requirements (ISO 10993). Safety evaluation studies (in vitro and in vivo) are conducted on a variety of biomaterials, medical devices, and related products to identify the presence of toxins or any other potentially harmful effects. Common assessments of device imaging are also briefly described. These include radiopacity as well as magnetic resonance imaging (MRI) safety and compatibility.

The Artificial Heart

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309045320
Total Pages : 313 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis The Artificial Heart by : Institute of Medicine

Download or read book The Artificial Heart written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: A significant medical event is expected in 1992: the first human use of a fully implantable, long-term cardiac assist device. This timely volume reviews the artificial heart program-and in particular, the National Institutes of Health's major investment-raising important questions. The volume includes: Consideration of the artificial heart versus heart transplantation and other approaches to treating end-stage heart disease, keeping in mind the different outcomes and costs of these treatments. A look at human issues, including the number of people who may require the artificial heart, patient quality of life, and other ethical and societal questions. Examination of how this technology's use can be targeted most appropriately. Attention to achieving access to this technology for all those who can benefit from it. The committee also offers three mechanisms to aid in allocating research and development funds.

Biomaterials for Cardiovascular Devices, Three Volume Set

Author : Yitzhak Rosen
Publisher :
ISBN 13 : 9781315372716
Total Pages : pages
Book Rating : 4.3/5 (727 download)

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Book Synopsis Biomaterials for Cardiovascular Devices, Three Volume Set by : Yitzhak Rosen

Download or read book Biomaterials for Cardiovascular Devices, Three Volume Set written by Yitzhak Rosen and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Flow Dynamics and Tissue Engineering of Blood Vessels

Author : Arindam Bit
Publisher : Myprint
ISBN 13 : 9780750320894
Total Pages : 316 pages
Book Rating : 4.3/5 (28 download)

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Book Synopsis Flow Dynamics and Tissue Engineering of Blood Vessels by : Arindam Bit

Download or read book Flow Dynamics and Tissue Engineering of Blood Vessels written by Arindam Bit and published by Myprint. This book was released on 2020-12 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flow Dynamics and Tissue Engineering of Blood Vessels explores the physical phenomena of vessel compliance and its influence on blood flow dynamics, as well as the modification of flow structures in the presence of diseases within the vessel wall or diseased blood content. This volume also illustrates the progress of tissue engineering for the intervention of re-engineered blood vessels. Blood vessel organoid models, their controlling aspects, and blood vessels based on microfluidic platforms are illustrated following on from the understanding of flow physics of blood on a similar platform. The purpose of this book is to provide an overview of regenerative medicine and fluid mechanics principles for the management of clinically diseased blood vessels. Authors discuss tissue engineering aspects and computational fluid mechanical principles, and how they can be used to understand the state of blood vessels in diseased conditions. Key Features Computational and experimental fluid dynamics principles have been used to explore the modelling of diseased blood vessels Principles of fluid dynamics and tissue engineering are used to propose innovative designs of bioreactors for blood vessel regeneration Offers experimental analytical studies of blood flow in vessels with pathological conditions Controlling aspects of various parameters while developing blood-vessel bioreactors and organoid models are presented critically, and optimization techniques for these parameters are also provided

Functionalised Cardiovascular Stents

Author : Gerard Wall
Publisher : Woodhead Publishing
ISBN 13 : 0081004982
Total Pages : 368 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Functionalised Cardiovascular Stents by : Gerard Wall

Download or read book Functionalised Cardiovascular Stents written by Gerard Wall and published by Woodhead Publishing. This book was released on 2018-02-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular disease is a major cause of mortality in the western world and about half of these deaths are caused by coronary artery disease. One of the most commonly used interventions to treat arterial blockages is to deploy an arterial stent to keep the vessel open. Traditionally, some cardiovascular stents have been associated with serious side-effects, such as thrombosis. This book describes the fundamentals of cardiovascular stents, technologies to functionalize their surfaces and the market status of these important implants. The chapters provide specific focus on the production and evolution of cardiovascular stents, providing essential knowledge for researchers on advances in the field and knowledge of how cardiovascular stents are currently being "functionalized" in order to improve their biocompatibility and minimize negative outcomes in vivo. Provides a specific focus on cardiovascular stents Includes a range of topics covering the fundamentals, surface modification and biofunctionalization Provides essential knowledge for researchers on advances in the field

Scientific Aspects of Dialysis Therapy

Author : H. Kawanishi
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318059293
Total Pages : 278 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Scientific Aspects of Dialysis Therapy by : H. Kawanishi

Download or read book Scientific Aspects of Dialysis Therapy written by H. Kawanishi and published by Karger Medical and Scientific Publishers. This book was released on 2016-12-12 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together papers presented both during the 61st Annual Meeting of the Japanese Society for Dialysis Therapy (JSDT) and the 34th Congress of the International Society of Blood Purification (ISBP), held in Osaka in June and in Hiroshima in September 2016, respectively. They cover a broad spectrum of topics, ranging from hemodialysis, peritoneal dialysis, hemodiafiltration and technical innovations in blood purification to complications of chronic kidney disease and acute kidney injury, including mineral bone disease and anemia.

Registries for Evaluating Patient Outcomes

Author : Agency for Healthcare Research and Quality/AHRQ
Publisher : Government Printing Office
ISBN 13 : 1587634333
Total Pages : 396 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis Registries for Evaluating Patient Outcomes by : Agency for Healthcare Research and Quality/AHRQ

Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.

Biomaterials Science

Author : William R Wagner
Publisher : Academic Press
ISBN 13 : 0128161388
Total Pages : 1612 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Biomaterials Science by : William R Wagner

Download or read book Biomaterials Science written by William R Wagner and published by Academic Press. This book was released on 2020-05-23 with total page 1612 pages. Available in PDF, EPUB and Kindle. Book excerpt: The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for most chapters

Materials for Biomedical Engineering

Author : Mohamed N. Rahaman
Publisher : John Wiley & Sons
ISBN 13 : 1119551099
Total Pages : 720 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Materials for Biomedical Engineering by : Mohamed N. Rahaman

Download or read book Materials for Biomedical Engineering written by Mohamed N. Rahaman and published by John Wiley & Sons. This book was released on 2021-11-01 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: MATERIALS FOR BIOMEDICAL ENGINEERING A comprehensive yet accessible introductory textbook designed for one-semester courses in biomaterials Biomaterials are used throughout the biomedical industry in a range of applications, from cardiovascular devices and medical and dental implants to regenerative medicine, tissue engineering, drug delivery, and cancer treatment. Materials for Biomedical Engineering: Fundamentals and Applications provides an up-to-date introduction to biomaterials, their interaction with cells and tissues, and their use in both conventional and emerging areas of biomedicine. Requiring no previous background in the subject, this student-friendly textbook covers the basic concepts and principles of materials science, the classes of materials used as biomaterials, the degradation of biomaterials in the biological environment, biocompatibility phenomena, and the major applications of biomaterials in medicine and dentistry. Throughout the text, easy-to-digest chapters address key topics such as the atomic structure, bonding, and properties of biomaterials, natural and synthetic polymers, immune responses to biomaterials, implant-associated infections, biomaterials in hard and soft tissue repair, tissue engineering and drug delivery, and more. Offers accessible chapters with clear explanatory text, tables and figures, and high-quality illustrations Describes how the fundamentals of biomaterials are applied in a variety of biomedical applications Features a thorough overview of the history, properties, and applications of biomaterials Includes numerous homework, review, and examination problems, full references, and further reading suggestions Materials for Biomedical Engineering: Fundamentals and Applications is an excellent textbook for advanced undergraduate and graduate students in biomedical materials science courses, and a valuable resource for medical and dental students as well as students with science and engineering backgrounds with interest in biomaterials.

Hemocompatibility of Biomaterials for Clinical Applications

Author : Christopher Siedlecki
Publisher : Woodhead Publishing
ISBN 13 : 0081004990
Total Pages : 482 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Hemocompatibility of Biomaterials for Clinical Applications by : Christopher Siedlecki

Download or read book Hemocompatibility of Biomaterials for Clinical Applications written by Christopher Siedlecki and published by Woodhead Publishing. This book was released on 2018-03-05 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemocompatibility of Biomaterials for Clinical Applications: Blood-Biomaterials Interactions summarizes the state-of-the-art on this important subject. The first part of the book reviews the latest research on blood composition and response, mechanisms of coagulation, test standards and methods. Next, the book assesses techniques for modifying biomaterial surfaces and developing coatings to improve hemocompatibility. In the final sections, users will find discussions on ways to improve the hemocompatibility of particular classes of biomaterials and a review of methods for improving medical devices. Provides comprehensive information on the fundamentals of hemocompatibility and new technologies Combines research in the biomaterials field in a digestible format for clinical applications Provides a complete overview biomaterials in current use and test methods

Organ Tissue Engineering

Author : Daniel Eberli
Publisher : Springer
ISBN 13 : 9783030442101
Total Pages : 0 pages
Book Rating : 4.4/5 (421 download)

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Book Synopsis Organ Tissue Engineering by : Daniel Eberli

Download or read book Organ Tissue Engineering written by Daniel Eberli and published by Springer. This book was released on 2021-04-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.

Biomaterials, Artificial Organs and Tissue Engineering

Author : L Hench
Publisher : Elsevier
ISBN 13 : 1845690869
Total Pages : 298 pages
Book Rating : 4.8/5 (456 download)

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Book Synopsis Biomaterials, Artificial Organs and Tissue Engineering by : L Hench

Download or read book Biomaterials, Artificial Organs and Tissue Engineering written by L Hench and published by Elsevier. This book was released on 2005-09-27 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Maintaining quality of life in an ageing population is one of the great challenges of the 21st Century. This book summarises how this challenge is being met by multi-disciplinary developments of specialty biomaterials, devices, artificial organs and in-vitro growth of human cells as tissue engineered constructs. Biomaterials, Artificial Organs and Tissue Engineering is intended for use as a textbook in a one semester course for upper level BS, MS and Meng students. The 25 chapters are organized in five parts: Part one provides an introduction to living and man-made materials for the non-specialist; Part two is an overview of clinical applications of various biomaterials and devices; Part three summarises the bioengineering principles, materials and designs used in artificial organs; Part four presents the concepts, cell techniques, scaffold materials and applications of tissue engineering; Part five provides an overview of the complex socio-economic factors involved in technology based healthcare, including regulatory controls, technology transfer processes and ethical issues. Comprehensive introduction to living and man-made materials Looks at clinical applications of various biomaterials and devices Bioengineering principles, materials and designs used in artificial organs are summarised

Biomaterials in the Design and Reliability of Medical Devices

Author : Michael N. Helmus
Publisher : Springer Science & Business Media
ISBN 13 : 9780306476907
Total Pages : 240 pages
Book Rating : 4.4/5 (769 download)

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Book Synopsis Biomaterials in the Design and Reliability of Medical Devices by : Michael N. Helmus

Download or read book Biomaterials in the Design and Reliability of Medical Devices written by Michael N. Helmus and published by Springer Science & Business Media. This book was released on 2003-01-31 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the responsibility of medical device designers and engineers to eliminate sites of failure and to test devices to demonstrate their ultimate safety and efficacy. It also evaluates biomaterials and their properties as related to the design and reliability of medical devices. The principles that are described are readily applicable to the biomaterial scaffolds used for generating tissue-engineered constructs.

Minimized Cardiopulmonary Bypass Techniques and Technologies

Author : Terence Gourlay
Publisher : Elsevier
ISBN 13 : 0857096028
Total Pages : 269 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Minimized Cardiopulmonary Bypass Techniques and Technologies by : Terence Gourlay

Download or read book Minimized Cardiopulmonary Bypass Techniques and Technologies written by Terence Gourlay and published by Elsevier. This book was released on 2012-04-19 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditional cardiopulmonary bypass (CPB) techniques have suffered from a number of disadvantages including haemodilution, inflammation and post-operative bleeding. Minimised cardiopulmonary bypass techniques use developments in perfusion technology to significantly reduce foreign surface-blood interactions to make bypass simpler and safer. This important book reviews key developments and issues relating to this promising technology.Part one covers the broad range of CPB pathophysiology, including anticoagulant protocols, the impact of CPB circuit surfaces, optimal haemodilution levels, and the important issue of CPB-induced systemic inflammatory response syndrome. Part two focuses on the issues of the new equipment developed for mini-CPB, optimal myocardial protection protocols and CPB perfusate options. Part three discusses clinical issues, including patient selection, coronary and valve surgery protocols and, among others, paediatric patients.With its distinguished editors and international team of expert contributors, Minimized cardiopulmonary bypass techniques and technologies is a valuable reference for cardiac surgery teams and those researching this important technology. Covers a broad range of cardiopulmonary bypass (CPB) pathophysiology, including anticoagulant protocols, the impact of CPB circuit surfaces and optimal haemodilution levels Focuses on new equipment specially developed for minimized-CPB and myocardial protection protocols Discusses clinical issues, including patient selection

Cardiovascular Biomechanics

Author : Peter R. Hoskins
Publisher : Springer
ISBN 13 : 3319464078
Total Pages : 462 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Cardiovascular Biomechanics by : Peter R. Hoskins

Download or read book Cardiovascular Biomechanics written by Peter R. Hoskins and published by Springer. This book was released on 2017-02-16 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.