Biological Timekeeping Clocks Rhythms And Behaviour

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Biological Timekeeping: Clocks, Rhythms and Behaviour

Author : Vinod Kumar
Publisher : Springer
ISBN 13 : 8132236882
Total Pages : 663 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Biological Timekeeping: Clocks, Rhythms and Behaviour by : Vinod Kumar

Download or read book Biological Timekeeping: Clocks, Rhythms and Behaviour written by Vinod Kumar and published by Springer. This book was released on 2017-02-15 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a concise, comprehensive and up-to-date account of fundamental concepts and potential applications of biological timekeeping mechanisms in animals and humans. It also discusses significant aspects of the organization and importance of timekeeping mechanisms in both groups. Divided into seven sections, it addresses important aspects including fundamental concepts; animal and human clocks; clock interactions; clocks and metabolism and immune functions; pineal, melatonin and timekeeping; and clocks, photoperiodism and seasonal behaviours. The book also focuses on biological clock applications in a 24x7 human society, particularly in connection with life-style associated disorders like obesity and diabetes. It is a valuable resource for advanced undergraduates, researchers and professionals engaged in the study of the science of biological timekeeping.

Biological Clocks, Rhythms, and Oscillations

Author : Daniel B. Forger
Publisher : MIT Press
ISBN 13 : 0262552817
Total Pages : 369 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Biological Clocks, Rhythms, and Oscillations by : Daniel B. Forger

Download or read book Biological Clocks, Rhythms, and Oscillations written by Daniel B. Forger and published by MIT Press. This book was released on 2024-08-06 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.

The Circadian Clock

Author : Urs Albrecht
Publisher : Springer Science & Business Media
ISBN 13 : 1441912622
Total Pages : 306 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis The Circadian Clock by : Urs Albrecht

Download or read book The Circadian Clock written by Urs Albrecht and published by Springer Science & Business Media. This book was released on 2010-01-23 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.

The Rhythms Of Life

Author : Leon Kreitzman
Publisher : Profile Books
ISBN 13 : 1847653723
Total Pages : 288 pages
Book Rating : 4.8/5 (476 download)

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Book Synopsis The Rhythms Of Life by : Leon Kreitzman

Download or read book The Rhythms Of Life written by Leon Kreitzman and published by Profile Books. This book was released on 2011-09-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Popular science at its most exciting: the breaking new world of chronobiology - understanding the rhythm of life in humans and all plants and animals. The entire natural world is full of rhythms. The early bird catches the worm -and migrates to an internal calendar. Dormice hibernate away the winter. Plants open and close their flowers at the same hour each day. Bees search out nectar-rich flowers day after day. There are cicadas that can breed for only two weeks every 17 years. And in humans: why are people who work anti-social shifts more illness prone and die younger? What is jet-lag and can anything help? Why do teenagers refuse to get up in the morning, and are the rest of us really 'larks' or 'owls'? Why are most people born (and die) between 3am-5am? And should patients be given medicines (and operations) at set times of day, because the body reacts so differently in the morning, evening and at night? The answers lie in our biological clocks the mechanisms which give order to all living things. They impose a structure that enables us to change our behaviour in relation to the time of day, month or year. They are reset at sunrise and sunset each day to link astronomical time with an organism's internal time.

Circadian Rhythms and Biological Clocks Part A

Author :
Publisher : Academic Press
ISBN 13 : 0128013419
Total Pages : 507 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Circadian Rhythms and Biological Clocks Part A by :

Download or read book Circadian Rhythms and Biological Clocks Part A written by and published by Academic Press. This book was released on 2015-01-30 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two new volumes of Methods in Enzymology continue the legacy of this premier serial with quality chapters authored by leaders in the field. Circadian Rhythms and Biological Clocks Part A and Part B is an exceptional resource for anybody interested in the general area of circadian rhythms. As key elements of timekeeping are conserved in organisms across the phylogenetic tree, and our understanding of circadian biology has benefited tremendously from work done in many species, the volume provides a wide range of assays for different biological systems. Protocols are provided to assess clock function, entrainment of the clock to stimuli such as light and food, and output rhythms of behavior and physiology. This volume also delves into the impact of circadian disruption on human health. Contributions are from leaders in the field who have made major discoveries using the methods presented here. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in biomineralization science - Keeping with the interdisciplinary nature of the circadian rhythm field, the volume includes diverse approaches towards the study of rhythms, from assays of biochemical reactions in unicellular organisms to monitoring of behavior in humans.

Human Circadian Physiology

Author : Charles A. Czeisler
Publisher :
ISBN 13 :
Total Pages : 692 pages
Book Rating : 4.:/5 (84 download)

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Book Synopsis Human Circadian Physiology by : Charles A. Czeisler

Download or read book Human Circadian Physiology written by Charles A. Czeisler and published by . This book was released on 1978 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chronobiology

Author : Jay C. Dunlap
Publisher : Sinauer Associates Incorporated
ISBN 13 : 9780878931491
Total Pages : 406 pages
Book Rating : 4.9/5 (314 download)

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Book Synopsis Chronobiology by : Jay C. Dunlap

Download or read book Chronobiology written by Jay C. Dunlap and published by Sinauer Associates Incorporated. This book was released on 2004 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of how solar- and lunar- related rhythms are governed by living pacemakers within organisms constitutes the scientific discipline of chronobiology. Few fields encompass the breadth of science that is associated with this subject, which is at the cutting edge of fields ranging from microbial genetics to ethology to treatment of human psychiatric illnesses. In order to recognise that no individual could do justice to the field in writing a comprehensive text, a group of experienced editors and contributors have collaborated to produce Chronobiology. Written in a clear style and fully illustrated to elucidate difficult points, the book assumes no previous background in neuroscience or maths and reduces technical terminology to a minimum. Examples from the real world and from current and classic research are included.

Insect Clocks

Author : David Stanley Saunders
Publisher :
ISBN 13 :
Total Pages : 279 pages
Book Rating : 4.:/5 (488 download)

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Book Synopsis Insect Clocks by : David Stanley Saunders

Download or read book Insect Clocks written by David Stanley Saunders and published by . This book was released on 1976 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ultradian Rhythms from Molecules to Mind

Author : David Lloyd
Publisher : Springer Science & Business Media
ISBN 13 : 1402083521
Total Pages : 445 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Ultradian Rhythms from Molecules to Mind by : David Lloyd

Download or read book Ultradian Rhythms from Molecules to Mind written by David Lloyd and published by Springer Science & Business Media. This book was released on 2008-08-27 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: 5. 1. 1 Biological Rhythms and Clocks From an evolutionary perspective, the adaptation of an organism’s behavior to its environment has depended on one of life’s fundamental traits: biological rhythm generation. In virtually all light-sensitive organisms from cyanobacteria to humans, biological clocks adapt cyclic physiology to geophysical time with time-keeping properties in the circadian (24 h), ultradian (24 h) domains (Edmunds, 1988; Lloyd, 1998; Lloyd et al. , 2001; Lloyd and Murray, 2006; Lloyd, 2007; Pittendrigh, 1993; Sweeney and Hastings, 1960) By definition, all rhythms exhibit regular periodicities since they constitute a mechanism of timing. Timing exerted by oscillatory mechanisms are found throughout the biological world and their periods span a wide range from milliseconds, as in the action potential of n- rons and the myocytes, to the slow evolutionary changes that require thousands of generations. In this context, to understand the synchronization of a population of coupled oscillators is an important problem for the dynamics of physiology in living systems (Aon et al. , 2007a, b; Kuramoto, 1984; Strogatz, 2003; Winfree, 1967). Circadian rhythms, the most intensively studied, are devoted to measuring daily 24 h cycles. A variety of physiological processes in a wide range of eukaryotic organisms display circadian rhythmicity which is characterized by the following major properties (Anderson et al. , 1985; Edmunds, 1988): (i) stable, autonomous (self-sustaining) oscillations having a free-running period under constant envir- mental conditions of ca.

Circannual Rhythms

Author : Eberhard Gwinner
Publisher : Springer Science & Business Media
ISBN 13 : 3642828701
Total Pages : 161 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Circannual Rhythms by : Eberhard Gwinner

Download or read book Circannual Rhythms written by Eberhard Gwinner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: In addition to the more or less static properties of the environ ment, plants and animals must cope with its temporal variations. Among the most conspicuous temporal changes to which organisms are exposed are periodic phenomena generated by the rotation of the earth about its axis, its revolution around the sun, and the more complex movements of the moon in relation to both sun and earth. The first two of these astronomical cycles are basic to the familiar daily and annual rhythms, respectively, in the environment. The third generates somewhat more complex cycles, such as those in moonlight and variations in tides. These environmental cycles have provided challenges and opportunities for organisms to adjust their physiology and behavior to them. Indeed, the predictability inherent to these periodic processes has enabled organisms to evolve innate endogenous rhythmic programs that match the environmental cycles and allow, in a variety of different ways, adjustment of biological activities to the cycles of environmental changes. The endogenous nature of rhythmicity was first clearly recognized in the 1930's in daily periodicities, the most widely distributed and best investigated class of biological rhythms of this type. In the 1950's, demonstrations of endogenous tidal and lunar rhythms, which occur in some littoral and marine organisms, ensued. Another decade passed before endogenous annual periodicities were first demonstrated unambiguously.

Circadian Rhythm Sleep-Wake Disorders

Author : R. Robert Auger
Publisher : Springer Nature
ISBN 13 : 3030438031
Total Pages : 251 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Circadian Rhythm Sleep-Wake Disorders by : R. Robert Auger

Download or read book Circadian Rhythm Sleep-Wake Disorders written by R. Robert Auger and published by Springer Nature. This book was released on 2020-05-26 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book resolves to bridge the communication gap between research and clinical practice for circadian rhythm sleep-wake disorders. Beginning with a scientific background on biological timekeeping, opening chapters describe the crucial nature of maintaining delicate temporal organization of physiological and molecular events within the body. Following this are discussions on circadian physiology and methods of circadian assessments. Subsequent chapters then relay comprehensive information regarding the International Classification of Sleep Disorders-defined circadian rhythm sleep-wake disorders (CRSWDs), specifically discussing etiology and epidemiology, but focusing on evidence-based treatment data. Concluding discussions provide guidance for the application of light therapy and discuss future roles for optimized lighting environments. Nuanced and market-demanded, Circadian Rhythm Sleep-Wake Disorders: An Evidence-Based Guide for Clinicians and Investigators is an invaluable resource for Sleep Medicine clinicians, circadian researchers, and other interested parties.

Neuroendocrine Clocks and Calendars

Author : Francis J. P. Ebling
Publisher : Springer Nature
ISBN 13 : 3030556433
Total Pages : 253 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Neuroendocrine Clocks and Calendars by : Francis J. P. Ebling

Download or read book Neuroendocrine Clocks and Calendars written by Francis J. P. Ebling and published by Springer Nature. This book was released on 2021-01-04 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores how daily and seasonal rhythmicity is generated, how these rhythms are synchronised by our environment, and how they regulate the neuroendocrine systems that impact our physiology and behaviour. The constraints of surviving in a seasonal environment have shaped human evolution and migration, have shaped our societies and cultures, and continue to influence our everyday lives, health and wellbeing. Identifying the mechanisms whereby seasonal rhythmicity is generated and regulates the brain and body is not only important for understanding the natural world and relevant to animal production, it also offers many insights into the human condition. Each chapter is written by an international expert in the field of chronobiology. A historical perspective on how research into photoperiodism and rhythmicity progressed is initially provided, but the main focus of this book is on the remarkable studies in the last few decades that have unravelled the molecular and cellular machinery underpinning circadian and circannual timing. Topics covered include the role of melatonin in communicating seasonal information to the brain and pituitary gland, the neuroanatomical pathways in mammals, birds and fish by which changes in photoperiod reach the hypothalamus, the role of glial cells (tanycytes) and thyroid hormone in seasonal rhythmicity, neuroplasticity across seasons, effects of changing day length on mood, regulation of “clock“ gene expression, and the role of the suprachiasmatic nucleus. This book will appeal to all students and researchers who wish to learn about current and past research on daily and seasonal rhythmicity. This is the tenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Circadian Rhythms and Metabolism

Author : Etienne Challet
Publisher : Frontiers Media SA
ISBN 13 : 2889452824
Total Pages : 190 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Circadian Rhythms and Metabolism by : Etienne Challet

Download or read book Circadian Rhythms and Metabolism written by Etienne Challet and published by Frontiers Media SA. This book was released on 2017-09-18 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major breakthroughs of the last decade in the understanding of energy homeostasis is the identification of a reciprocal control between circadian rhythmicity and cellular metabolism. Circadian rhythmicity is a fundamental endogenous process of almost every organism living on Earth. For instance, the alternation of hunger and satiety is not continuous over 24 h, but is instead structured in time along the light/dark cycle. In mammals, the temporal organization of metabolism, physiology and behavior around 24 h is controlled by a network of multiple cellular clocks, synchronized via neuronal and hormonal signals by a master clock located in the suprachiasmatic nuclei of the hypothalamus. This central circadian conductor in the brain is mainly reset by ambient light perceived by the retina, while secondary circadian clocks in other brain areas and peripheral organs can be reset by meal timing. Chronic disruption of circadian rhythms, as seen in human shift-workers (up to 20% of the active population), has been associated with the development of a number of adverse mental and metabolic conditions. Understanding of the functional links between circadian desynchronization and overall health in animal models and humans, however, is still scarce. Interactions between circadian clocks and metabolism can occur at different levels: the molecular clockwork, internal synchronization via neuro-hormonal signals, or external synchronization via photic or feeding cues. This Research Topic comprises a number of reviews as well as research and methods articles that feature recent advancements in the mechanisms linking circadian clocks with energy metabolism, and the pathophysiological implications of these interactions for metabolic health.

The Human Cosmos

Author : Jo Marchant
Publisher : Penguin
ISBN 13 : 0593183045
Total Pages : 401 pages
Book Rating : 4.5/5 (931 download)

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Book Synopsis The Human Cosmos by : Jo Marchant

Download or read book The Human Cosmos written by Jo Marchant and published by Penguin. This book was released on 2021-09-07 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Best Book of 2020 (NPR) A Best Book of 2020 (The Economist) A Top Ten Best Science Book of 2020 (Smithsonian) A Best Science and Technology Book of 2020 (Library Journal) A Must-Read Book to Escape the Chaos of 2020 (Newsweek) Starred review (Booklist) Starred review (Publishers Weekly) A historically unprecedented disconnect between humanity and the heavens has opened. Jo Marchant's book can begin to heal it. For at least 20,000 years, we have led not just an earthly existence but a cosmic one. Celestial cycles drove every aspect of our daily lives. Our innate relationship with the stars shaped who we are—our art, religious beliefs, social status, scientific advances, and even our biology. But over the last few centuries we have separated ourselves from the universe that surrounds us. It's a disconnect with a dire cost. Our relationship to the stars and planets has moved from one of awe, wonder and superstition to one where technology is king—the cosmos is now explored through data on our screens, not by the naked eye observing the natural world. Indeed, in most countries, modern light pollution obscures much of the night sky from view. Jo Marchant's spellbinding parade of the ways different cultures celebrated the majesty and mysteries of the night sky is a journey to the most awe-inspiring view you can ever see: looking up on a clear dark night. That experience and the thoughts it has engendered have radically shaped human civilization across millennia. The cosmos is the source of our greatest creativity in art, in science, in life. To show us how, Jo Marchant takes us to the Hall of the Bulls in the caves at Lascaux in France, and to the summer solstice at a 5,000-year-old tomb at Newgrange, Ireland. We discover Chumash cosmology and visit medieval monks grappling with the nature of time and Tahitian sailors navigating by the stars. We discover how light reveals the chemical composition of the sun, and we are with Einstein as he works out that space and time are one and the same. A four-billion-year-old meteor inspires a search for extraterrestrial life. The cosmically liberating, summary revelation is that star-gazing made us human.

Space, Time and the Limits of Human Understanding

Author : Shyam Wuppuluri
Publisher : Springer
ISBN 13 : 3319444182
Total Pages : 524 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Space, Time and the Limits of Human Understanding by : Shyam Wuppuluri

Download or read book Space, Time and the Limits of Human Understanding written by Shyam Wuppuluri and published by Springer. This book was released on 2016-12-01 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this compendium of essays, some of the world’s leading thinkers discuss their conceptions of space and time, as viewed through the lens of their own discipline. With an epilogue on the limits of human understanding, this volume hosts contributions from six or more diverse fields. It presumes only rudimentary background knowledge on the part of the reader. Time and again, through the prism of intellect, humans have tried to diffract reality into various distinct, yet seamless, atomic, yet holistic, independent, yet interrelated disciplines and have attempted to study it contextually. Philosophers debate the paradoxes, or engage in meditations, dialogues and reflections on the content and nature of space and time. Physicists, too, have been trying to mold space and time to fit their notions concerning micro- and macro-worlds. Mathematicians focus on the abstract aspects of space, time and measurement. While cognitive scientists ponder over the perceptual and experiential facets of our consciousness of space and time, computer scientists theoretically and practically try to optimize the space-time complexities in storing and retrieving data/information. The list is never-ending. Linguists, logicians, artists, evolutionary biologists, geographers etc., all are trying to weave a web of understanding around the same duo. However, our endeavour into a world of such endless imagination is restrained by intellectual dilemmas such as: Can humans comprehend everything? Are there any limits? Can finite thought fathom infinity? We have sought far and wide among the best minds to furnish articles that provide an overview of the above topics. We hope that, through this journey, a symphony of patterns and tapestry of intuitions will emerge, providing the reader with insights into the questions: What is Space? What is Time? Chapter [15] of this book is available open access under a CC BY 4.0 license.

Vertebrate Circadian Systems

Author : J. Aschoff
Publisher : Springer Science & Business Media
ISBN 13 : 3642686516
Total Pages : 376 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Vertebrate Circadian Systems by : J. Aschoff

Download or read book Vertebrate Circadian Systems written by J. Aschoff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The ADME Encyclopedia

Author : Alan Talevi
Publisher : Springer Nature
ISBN 13 : 3030848604
Total Pages : 1209 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis The ADME Encyclopedia by : Alan Talevi

Download or read book The ADME Encyclopedia written by Alan Talevi and published by Springer Nature. This book was released on 2022-06-14 with total page 1209 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ADME Encyclopedia covers pharmacokinetic phenomena (Absorption, Distribution, Metabolism and Excretion processes) and their relationship with the design of pharmaceutical carriers and the success of drug therapies. It covers both basic and advanced knowledge, serving as introductory material for students of biomedical careers and also as reference, updated material for graduates and professionals working in any field related to pharmaceutical sciences (medicine, pharmaceutical technology, materials science, medicinal chemistry). Structured as alphabetically ordered entries with cross-references, the Encyclopedia not only provides basic knowledge on ADME processes, but also detailed entries on some advanced subjects such as drug transporters, last generation pharmaceutical carriers, pharmacogenomics, personalized medicine, bioequivalence studies, biowaivers, biopharmaceuticals, gene delivery, pharmacometrics, pharmacokinetic drug interactions or in silico and in vitro assessment of ADME properties