Bioactive Metabolites From Microorganisms

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The Search for Bioactive Compounds from Microorganisms

Author : Satoshi Omura
Publisher : Springer Science & Business Media
ISBN 13 : 1461244129
Total Pages : 373 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis The Search for Bioactive Compounds from Microorganisms by : Satoshi Omura

Download or read book The Search for Bioactive Compounds from Microorganisms written by Satoshi Omura and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biologically active compounds isolated from microorganisms continue to be vital to the development of new drugs and agricultural chemicals. This book was prepared by current and past members of the laboratory of Dr. Satoshi Omura of the Kitasato Institute in Japan. Dr. Omura and his colleagues have discovered and studied a number of important antibiotics, and in their work they have pioneered new methods for screening microbes for interesting and important compounds. This book presents strategies and methods for identifying novel molecules with several types of biological activity. In addition, the book discusses the identification of microbial compounds of agrochemical importance, presents information on chemical screening methods, and concludes with chapters on microbial strain selection, fermentation technology, and genetic engineering of antibiotic-producing microorganisms. This book will be of great interest to scientists working in the very active and competitive fields of antibiotic and agrochemical discovery.

Bioactive Metabolites from Microorganisms

Author : M. E. Bushell
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 438 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Bioactive Metabolites from Microorganisms by : M. E. Bushell

Download or read book Bioactive Metabolites from Microorganisms written by M. E. Bushell and published by Elsevier Publishing Company. This book was released on 1989 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes major approaches and recent developments in the research on new bioactive metabolites of microbial origin including target-directed screening strategies, evaluation of new drugs, biosynthesis, genetic manipulation, and semisynthesis. Particular attentonis given to new microbial sources of drugs, new approaches towards directed screening, advances and future perspectives in antimicrobial, antineoplastic and phytoeffectory agents, and enzyme inhibitors as pharmacological agents. The contributions represent comprehensive surveys written by recognized scientists active in their fields of research. Together, they give an interdisciplinary view which focusses on exploitation of available microbial sources for drug development, problems of evaluation, mode of action, biosynthesis and application. The book will be of interest to scientists working in microbiology, pharmacology, pharmaceutical chemistry and pharmaceutical biotechnology.

The Need to Use Microorganisms and Their Biosynthesized Bioactive Metabolites for Biological and Medical Activities

Author : Zeinab Amanzadeh
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis The Need to Use Microorganisms and Their Biosynthesized Bioactive Metabolites for Biological and Medical Activities by : Zeinab Amanzadeh

Download or read book The Need to Use Microorganisms and Their Biosynthesized Bioactive Metabolites for Biological and Medical Activities written by Zeinab Amanzadeh and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some microorganisms (MOs) such as bacteria, fungi and aquatic creatures synthesize bioactive secondary metabolites synthesis that known as natural products. A series of landmark metabolomics studies by using mass spectrometry (MS) or nuclear magnetic resonance (NMR) analysis to identify potentially important microbial metabolites that derive from the intestine microbes. Vital roles for numerous microbial metabolic pathways in host physiology had been long established, such as in the synthesis of vitamin K and the synthesis of water-soluble B vitamins including biotin, folates, nicotinic acid, pyridoxine, riboflavin, cobalamin and panthotenic acid, the degradation of nutritional oxalates, and amendment of bile salts. These metabolites have biological and medical activities. The medical activities including antimicrobial, immunosuppressive, anticancer, and anti-inflammatory, antibiotic, antitumor, antioxidant activities, etc. Also biological activities derive from metabolites microbial transformation have effects on physiological processes such as gut and immune homeostasis, energy metabolism, vascular function, and neurological behavior such as short-chain fatty acids, trimethylamine N-oxide, tryptophan and tyrosine derivatives, and oxidized fatty acids. Using recombinant DNA technology synthesize a wide array of biopharmaceutical products, such as recombinant proteins, offering significant advances in treating a broad spectrum of medical. Such interventions will require modulating either bacterial species or the bacterial biosynthetic enzymes required to synthesis these metabolites.

Volatiles and Metabolites of Microbes

Author : Ajay Kumar
Publisher : Academic Press
ISBN 13 : 0323851649
Total Pages : 513 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Volatiles and Metabolites of Microbes by : Ajay Kumar

Download or read book Volatiles and Metabolites of Microbes written by Ajay Kumar and published by Academic Press. This book was released on 2021-06-22 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volatiles and Metabolites of Microbes compiles the latest research and advancement in the field of volatiles, metabolites synthesized from the microbial strains such as actinomycetes, bacteria, cyanobacteria, and fungal species and their potential applications in the field of healthcare issue and sustainable agriculture. There is an urgent need to explore new and advanced biological methods for health industries and sustainable agriculture and to protect the environment from environmental pollution or contaminates, global warming, and also control the health of human beings from the side effects of various pharmaceuticals products. Focusing all these factors, Volatiles and Metabolites of Microbes explores new aspects of microorganism in terms of volatiles, enzymes, bioactive compounds synthesized from the microbes and their potential applications in the field of sustainable agriculture and health-related issues Provides a broad aspect about volatiles, bioactive compounds, and secondary metabolites of microbes compiled in one cover Gives the latest research and advancement in the field of volatiles, secondary metabolites, and bioactive compounds synthesized from the different microbial strains Responds to new developments in the detection of the complex compound structures of volatiles Offers insight to a very broad audience in Biotechnology, Applied Microbiology, Agronomy, and Pathology

Biotechnology of Bioactive Compounds

Author : Vijai Kumar Gupta
Publisher : John Wiley & Sons
ISBN 13 : 1118733495
Total Pages : 742 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Biotechnology of Bioactive Compounds by : Vijai Kumar Gupta

Download or read book Biotechnology of Bioactive Compounds written by Vijai Kumar Gupta and published by John Wiley & Sons. This book was released on 2015-04-20 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.

Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites

Author : G. Lancini
Publisher : Springer Science & Business Media
ISBN 13 : 147579522X
Total Pages : 240 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites by : G. Lancini

Download or read book Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites written by G. Lancini and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the field's need for an introductory text, the authors have distilled the vast and scattered literature relating to the biotechnology of microbial secondary metabolites. General biology, biosynthesis, the search for novel metabolites, and techniques for strain improvement are all discussed to provide undergraduate and graduate students with a concise, readable overview of the field.

Actinobacteria: Prolific Producers of Bioactive Metabolites

Author : Learn-Han Lee
Publisher : Frontiers Media SA
ISBN 13 : 2889660877
Total Pages : 138 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Actinobacteria: Prolific Producers of Bioactive Metabolites by : Learn-Han Lee

Download or read book Actinobacteria: Prolific Producers of Bioactive Metabolites written by Learn-Han Lee and published by Frontiers Media SA. This book was released on 2020-12-09 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Bioactive Compounds from Microbes

Author : Roberto Mazzoli
Publisher : Frontiers Media SA
ISBN 13 : 2889451852
Total Pages : 144 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Bioactive Compounds from Microbes by : Roberto Mazzoli

Download or read book Bioactive Compounds from Microbes written by Roberto Mazzoli and published by Frontiers Media SA. This book was released on 2017-06-02 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microorganisms have had a long and surprising history. They were “invisible” until invention of microscope in the 17th century. Until that date, although they were extensively (but inconsciously) employed in food preservation, beer and wine fermentation, cheese, vinegar, yogurt and bread making, as well as being the causative agents of infectious diseases, they were considered as “not-existing”. The work of Pasteur in the middle of the 19th century revealed several biological activities performed by microorganisms including fermentations and pathogenicity. Due to the urgent issue to treat infectious diseases (the main cause of death at those times) the “positive potential” of the microbial world has been neglected for about one century. Once the fight against the “evil” strains was fulfilled also thanks to the antibiotics, industry began to appreciate bacteria’s beneficial characteristics and exploit selected strains as starters for both food fermentations and aroma, enzyme and texturing agent production. However, it was only at the end of the 20th century that the probiotic potential of some bacteria such as lactic acid bacteria and bifidobacteria was fully recognized. Very recently, apart from the probiotic activity of in toto bacteria, attention has begun to be directed to the chemical mediators of the probiotic effect. Thanks also to the improvement of techniques such as transcriptomics, proteomics and metabolomics, several bioactive compounds are continuously being discovered. Bioactive molecules produced by bacteria, yeasts and virus-infected cells proved to be important for improving or impairing human health. The most important result of last years’ research concerns the discovery that a very complex network of signals allows communication between organisms (from intra-species interactions to inter-kingdom signaling). Based on these findings a completely new approach has arisen: the system biology standpoind. Actually, the different organisms colonizing a certain environmental niche are not merely interacting with each other as individuals but should be considered as a whole complex ecosystem continuously exchanging information at the molecular level. In this context, this topic issue explores both antagonistic compounds (i.e. antibiotics) and “multiple function” cooperative molecules improving the physiological status of both stimulators and targets of this network. From the applicative viewpoint, these molecules could be hopefully exploited to develop new pharmaceuticals and/or nutraceuticals for improving human health.

Pharmaceuticals from Microbes

Author : Divya Arora
Publisher : Springer
ISBN 13 : 3030046753
Total Pages : 226 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Pharmaceuticals from Microbes by : Divya Arora

Download or read book Pharmaceuticals from Microbes written by Divya Arora and published by Springer. This book was released on 2019-02-12 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the noteworthy advancement in the production of bioactive metabolites from microbes and their pharmacological significance. It highlights the pharmacological potential of marine microbes and endophytic fungi and their bioactive secondary metabolites. Emphasis is also given on the significance of probiotics and their specialized molecules in human health and disease as well as their role in dietary intervention for reducing the risk of non-alcoholic fatty liver disease. This work also serves as excellent reference material for researchers, students and academicians in the field of natural product chemistry, pharmacology and applied microbiology.

Marine Microorganisms

Author : Leo M.L. Nollet
Publisher : CRC Press
ISBN 13 : 1315354551
Total Pages : 130 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Marine Microorganisms by : Leo M.L. Nollet

Download or read book Marine Microorganisms written by Leo M.L. Nollet and published by CRC Press. This book was released on 2016-09-19 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: The marine environment covers 70% of the earth’s surface and accounts for 98% of the potentially habitable space. The bioactives from marine microorganisms include antibiotic compounds, polysaccharides, inhibitors, enzymes, peptides, and pigments. These are used in various fields of biology that range from nutraceuticals to cosmeceuticals. Recent scientific investigations have revealed that marine microbial compounds exhibit various beneficial biological effects, such as anti-inflammatory, anti-cancer, anti-HIV, anti-hypertensive, and anti-diabetic. Marine Microorganisms: Extraction and Analysis of Bioactive Compounds sheds light on the extraction, clean-up, and detection methods of major compounds from marine organisms. The book includes information on the different classes of marine microorganisms and the different bioactives that can be extracted from bacteria, fungi and microalgae. Divided into 7 chapters, the book covers bioactive marine natural products, such as marine microbes, seaweeds, and marine sponges as potential sources of drug discovery, and focuses on analysis methods of the biocomponents from marine microorganisms. A useful reference tool for researchers and students, this book provides current knowledge about isolation and analysis methods of the bioactives and provides insight into the various bioactives of marine microbes toward nutraceutical and pharmaceutical development.

Microbial Secondary Metabolites and Biotechnology

Author :
Publisher :
ISBN 13 : 9783036532462
Total Pages : 464 pages
Book Rating : 4.5/5 (324 download)

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Book Synopsis Microbial Secondary Metabolites and Biotechnology by :

Download or read book Microbial Secondary Metabolites and Biotechnology written by and published by . This book was released on 2022-03-02 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioactive Metabolites from Microorganisms

Author : Allison K. Drummond
Publisher :
ISBN 13 :
Total Pages : 168 pages
Book Rating : 4.:/5 (718 download)

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Book Synopsis Bioactive Metabolites from Microorganisms by : Allison K. Drummond

Download or read book Bioactive Metabolites from Microorganisms written by Allison K. Drummond and published by . This book was released on 2006 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microbial Secondary Metabolites: Recent Developments and Technological Challenges

Author : Bhim Pratap Singh
Publisher : Frontiers Media SA
ISBN 13 : 2889459012
Total Pages : 309 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Microbial Secondary Metabolites: Recent Developments and Technological Challenges by : Bhim Pratap Singh

Download or read book Microbial Secondary Metabolites: Recent Developments and Technological Challenges written by Bhim Pratap Singh and published by Frontiers Media SA. This book was released on 2019-08-02 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on microbes plays an essential role in the improvement of biotechnological and biomedical areas. It has turned into a subject of expanding significance as new organisms and their related biomolecules are being characterized for several applications in health and agriculture. Microbial biomolecules confer the ability of microbes to cope with a range of adverse conditions. However, these biomolecules have several advantages over the plant origin, which makes them a suitable target in drug discovery and development. The reasons could be that microbial sources can be genetically engineered to enhance the production of desired natural production by large-scale fermentation. The interaction between microbes and their biotic and abiotic environment is fundamental to numerous processes taking place in the biosphere. The natural environments and hosts of these microorganisms are extremely diverse being reflected by the fact that microbes are widespread and occur in nearly every biological community on Earth. This metabolic versatility makes microbes interesting objects for a range of economically important biotechnological applications. Most of the biotechniques are established but inefficient genetic engineering strategies are still a bottleneck for selected microbe producing industrial scale biomolecules. Therefore, untapped microbial biodiversity and related metablomics, give a noteworthy wellspring of biologicals for the advancement of meds, immunizations, enhanced plants and for other natural applications. The present eBook volume contains articles on microbial secondary metabolites, microbial biosynthetic potential including biosynthetic gene expression, and metagenomics obtained from microorganism isolated unique from habitats like marine sources, endophytes, thermal springs, deserts, etc.

Bioactive Compounds from Terrestrial Extremophiles

Author : Lesley-Ann Giddings
Publisher : Springer
ISBN 13 : 3319132601
Total Pages : 95 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Bioactive Compounds from Terrestrial Extremophiles by : Lesley-Ann Giddings

Download or read book Bioactive Compounds from Terrestrial Extremophiles written by Lesley-Ann Giddings and published by Springer. This book was released on 2014-11-21 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: A discussion of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or leads to novel drugs for human use. This SpringerBrief deals with bioactive materials from terrestrial extremophiles.

Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites

Author : G. Lancini
Publisher :
ISBN 13 : 9781475795233
Total Pages : 248 pages
Book Rating : 4.7/5 (952 download)

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Book Synopsis Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites by : G. Lancini

Download or read book Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites written by G. Lancini and published by . This book was released on 2014-01-15 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioactive Microbial Metabolites

Author : Vaibhav Mishra
Publisher : Elsevier
ISBN 13 : 0443185697
Total Pages : 368 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Bioactive Microbial Metabolites by : Vaibhav Mishra

Download or read book Bioactive Microbial Metabolites written by Vaibhav Mishra and published by Elsevier. This book was released on 2024-06-01 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive Microbial Metabolites: Scope and Challenges not only focuses on the identification, separation and purification of bioactive metabolites, the book also provides an understanding of the metabolic pathways for bioactive metabolites production that play an important role in modern healthcare as frontline treatments for many diseases. This is a valuable reference for research students, academicians and scientists in environmental microbiology and biotechnology, and for industry personnel related to microbiology/ biotechnology. The science discussed herein plays an important role in expanding the market of antibiotics, food and agriculture but also offers eco-friendly, safer and profitable solutions to respective industries. Focuses on the identification and structure elucidation of novel microbial metabolites Uncovers extended functions of microbial metabolites Provides understanding of metabolic pathways for bioactive metabolites production by using several illustrations, figures and tables so that the readers can easily grasp key concepts

Marine Microbiology

Author : Se-Kwon Kim
Publisher : John Wiley & Sons
ISBN 13 : 3527665277
Total Pages : 558 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Marine Microbiology by : Se-Kwon Kim

Download or read book Marine Microbiology written by Se-Kwon Kim and published by John Wiley & Sons. This book was released on 2013-06-21 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deliberately breaking with the classical biology-centered description of marine organisms and their products, this reference emphasizes microbial technology over basic biology, setting it apart from its predecessors. As such, it systematically covers the technology behind high-value compounds for use as pharmaceuticals, nutraceuticals or cosmetics, from prospecting to production issues. Following a definition of the field, the book goes on to address all industrially important aspects of marine microbial biotechnology. The first main part contains a description of the major production organisms, from archaebacteria to cyanobacteria to algae and symbionts, including their genetic engineering. The remaining four parts look at commercially important compounds produced by these microorganisms together with their applications. Throughout, the emphasis is on technological considerations, and the future potential of these organisms or compound classes is discussed. A valuable and forward-looking resource for innovative biotechnologists in industry as well as in academia.