Fractal Binding and Dissociation Kinetics for Different Biosensor Applications

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Publisher : Elsevier
ISBN 13 : 9780080458915
Total Pages : 650 pages
Book Rating : 4.4/5 (589 download)

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Book Synopsis Fractal Binding and Dissociation Kinetics for Different Biosensor Applications by : Ajit Sadana

Download or read book Fractal Binding and Dissociation Kinetics for Different Biosensor Applications written by Ajit Sadana and published by Elsevier. This book was released on 2005-07-06 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensors are portable and convenient devices that permit the rapid and reliable analysis of substances. They are increasingly used in healthcare, drug design, environmental monitoring and the detection of biological, chemical, and toxic agents. Fractal Binding and Dissociation Kinetics for Different Biosensor Applications focuses on two areas of expanding biosensor development that include (a) the detection of biological and chemical pathogens in the atmosphere, and (b) biomedical applications, especially in healthcare. The author provides numerous examples of practical uses, particularly biomedical applications and the detection of biological or chemical pathogens. This book also contains valuable information dedicated to the economics of biosensors. After reading this book, the reader will gain invaluable insight into how biosensors work and how they may be used more effectively. * No other book provides a detailed kinetic analysis of the binding and dissociation reactions occurring on the biosensor surfaces * Packed with examples of practical uses of biosensors * Includes chapters dedicated to the economics of biosensors

Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals

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Publisher : Elsevier
ISBN 13 : 9780080463698
Total Pages : 384 pages
Book Rating : 4.4/5 (636 download)

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Book Synopsis Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals by : Ajit Sadana

Download or read book Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals written by Ajit Sadana and published by Elsevier. This book was released on 2006-08-08 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of biosensors is expanding in different areas. These are portable and convenient devices that permit the rapid, accurate, and reliable detection of analytes of interest present either in the atmosphere or in aqueous or in liquid phases. The detection of glucose levels in blood for the effective management of diabetes is one. Though different biosensors have been designed for an increasing number of applications, the kinetics of binding (and dissociation) of analytes by the receptors on the biosensor surfaces has not been given enough attention in the open literature. This is a very important area of investigation since it significantly impacts biosensor performance parameters such as stability, sensitivity, selectivity, response time, regenerability, etc. Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals addresses this critical need besides helping to correct or demonstrate the need to modify the present software available with commercial biosensors that determines the kinetics of analyte-receptor reactions on biosensor surfaces. * first book to provide detailed kinetic analysis of the binding and dissociation reactions that are occuring on the biosensor surface * addresses the area of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces * provides physical insights into reactions occuring on biosensor surfaces

Biosensors: Kinetics of Binding and Dissociation Using Fractals

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Author :
Publisher : Elsevier
ISBN 13 : 9780080528137
Total Pages : 418 pages
Book Rating : 4.5/5 (281 download)

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Book Synopsis Biosensors: Kinetics of Binding and Dissociation Using Fractals by : Ajit Sadana

Download or read book Biosensors: Kinetics of Binding and Dissociation Using Fractals written by Ajit Sadana and published by Elsevier. This book was released on 2003-12-17 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title brings to the attention of researchers in the industry, and in academia, the application of fractals to help in modeling the analyte/receptor binding and dissociation kinetics on biosensor surfaces. The work builds on that done in Engineering Biosensors: Kinetics and Design Applications, published by Academic Press in 2002. In particular, more examples are provided of where biosensors may be effectively used. This sequel is extremely timely, given the anticipation that the applications and reliance on biosensors will increase due to the advances in miniaturization, (wireless) communications, and the development of new materials (especially biological and chemical). Other applications of biosensors on the increase can be found in: the protection of civilian structures and infrastructures; protection from possible biological and chemical threats; health care; energy; food safety; and the environment to name a few. Covers all areas of applications of biosensors No other book on biosensors describes the kinetics of binding Provides numerous examples of where biosensors may be used

Biosensors: Kinetics of Binding and Dissociation Using Fractals

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Author :
Publisher : Elsevier
ISBN 13 : 9780444515124
Total Pages : 426 pages
Book Rating : 4.5/5 (151 download)

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Book Synopsis Biosensors: Kinetics of Binding and Dissociation Using Fractals by : Ajit Sadana

Download or read book Biosensors: Kinetics of Binding and Dissociation Using Fractals written by Ajit Sadana and published by Elsevier. This book was released on 2003-12-17 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Effect of Reynolds number on fractal binding kinetics on a surface-based biosensor -- DNA fractal binding and dissociation kinetics -- Fractal analysis of binding and dissociation interactions of estrogen receptors to ligands on biosensor surfaces -- A fractal analysis of analyte-estrogen receptor binding and dissociation kinetics using biosensors : environmental effects -- A fractal analysis of analyte-estrogen receptor binding and dissociation kinetics using biosensors : biomedical effects -- Fractal analysis of binding interactions of nuclear estrogen receptors occurring on biosensor surfaces -- A kinetic study of analyte-receptor binding and dissociation for biosensor applications : a fractal analysis for cholera toxin and peptide-protein interactions / -- The temporal nature of the binding and dissociation rate coefficients and the affinity values for biosensor kinetics -- Fractal analysis of analyte-receptor binding and dissociation, and dissociation alone for biosensor applicati ...

Fractal Analysis of the Binding and Dissociation Kinetics for Different Analytes on Biosensor Surfaces

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Publisher : Elsevier
ISBN 13 : 9780080555010
Total Pages : 372 pages
Book Rating : 4.5/5 (55 download)

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Book Synopsis Fractal Analysis of the Binding and Dissociation Kinetics for Different Analytes on Biosensor Surfaces by : Ajit Sadana

Download or read book Fractal Analysis of the Binding and Dissociation Kinetics for Different Analytes on Biosensor Surfaces written by Ajit Sadana and published by Elsevier. This book was released on 2007-12-20 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensors are finding increasing applications in different areas. Over the last few years the areas where biosensors may be used effectively has increased dramatically. This book like the previous four books on analyte-receptor binding and dissociation kinetics by this author addresses the often neglected area. The kinetics of binding and dissociation in solution to appropriate receptors immobilized on biosensor surfaces occurs under diffusional limitations on structured surfaces. The receptors immobilized on the biosensor surface contribute to the degree of heterogeneity on the sensor chip surface. The fractal analysis examples presented throughout the book provide a convenient means to make quantitative the degree of heterogeneity present on the sensor surface, and relates it to the binding and dissociation rate coefficients. The fractal dimension is a quantitative measure of the degree of heterogeneity present on the biosensor surface. The book emphasizes medially-oriented examples. The detection of disease-related analytes is also emphasized. The intent being that if intractable and insidious diseases are detected earlier, they will be controlled better, eventually leading to a better prognosis. Chapter 3 is a new chapter that emphasizes enhancing the relevant biosensor performance parameters such as sensitivity, stability, selectivity, response time, etc. As usual, as done in previous books by this author, the last chapter provides an update of the economics involved in biosensors, and the difficulties encounters in starting-up a biosensor company. - Modelling of binding and dissociation kinetics of analyte-receptor reactions on biosensor surfaces: provides physical insights into these reactions occurring on biosensor surfaces. Very few researchers even attempt to analyze the kinetics of these types of reactions. - Fractal analysis used to model the binding and dissociation kinetics: original and unique approach. - Economic analysis provided in the last chapter: helps balance the book; besides providing much-needed information not available in the open literature. - Emphasis on improving biosensor performance parameters: helps make biosensors better. - Empahsis on medically-related analytes: helps in prognosis of diseases.

A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces

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Author :
Publisher : Elsevier
ISBN 13 : 0444638822
Total Pages : 337 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces by : Ajit Sadana

Download or read book A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces written by Ajit Sadana and published by Elsevier. This book was released on 2018-07-31 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces analyzes the kinetics of binding and dissociation of different analytes by different biosensor techniques, demonstrating and then comparing each. Emphasis is placed on newer instrumentation techniques, such as SPRi (surface plasmon resonance imaging), and classical techniques, such as SPR (surface plasmon resonance), and finally, DNA biosensors and nanobiosensors. In addition, a final capstone chapter includes biosensor economics. These topics are all covered in one comprehensive book in a way that cannot be found elsewhere. Analyzes the kinetics of binding on biosensor surfaces Presents and compares different biosensor techniques Provides insights into the binding and dissociation mechanisms of analytes on biosensor surfaces Links the heterogeneity of biosensor surfaces to dissociation rate coefficients

Sensor Technology in Neuroscience

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849735417
Total Pages : 250 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Sensor Technology in Neuroscience by : Michael Thompson

Download or read book Sensor Technology in Neuroscience written by Michael Thompson and published by Royal Society of Chemistry. This book was released on 2013-08-14 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensor technology has rapidly expanded into a wide variety of applications in the last few years. Such fields include clinical diagnostics, environmental chemistry, drug discovery and pathogen detection, to name but a few. The structure of these sensors is based on the intimate combination of a biological entity with a transducer capable of generating an electrical signal to provide information on the biological system being studied. Until now there has been a limited treatment of the study of whole cells (as a biological component) due to the difficulty in connecting transducers to cell populations. This book focuses on several aspects of neural behaviour both in vitro and in vivo, and for the first time, the detection of populations of neurons (rather than single cells) will be presented. The fundamental behaviour and characterization of neurons on various substrates, using a variety of electronic devices such as transistors and microelectrode arrays will be discussed. Future perspectives discussed in the book include artificial intelligence using biological neural networks and nanoneuromedicine. The authors have considerable experience in biosensor technology, and have pioneered the study of neural populations using biosensors in collaboration with neurophysiologists and neuroendrocrinologists. This book will be invaluable to university neuroscience and analytical chemistry departments and students, academics and physicians will benefit from its accessible style and format.

Handbook of Biosensors and Biosensor Kinetics

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Publisher : Elsevier
ISBN 13 : 9780080932859
Total Pages : 536 pages
Book Rating : 4.9/5 (328 download)

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Book Synopsis Handbook of Biosensors and Biosensor Kinetics by : Ajit Sadana

Download or read book Handbook of Biosensors and Biosensor Kinetics written by Ajit Sadana and published by Elsevier. This book was released on 2010-08-26 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensors are essential to an ever-expanding range of applications, including healthcare; drug design; detection of biological, chemical, and toxic agents; environmental monitoring; biotechnology; aviation; physics; oceanography; and the protection of civilian and engineering infrastructures. This book, like the previous five books on biosensors by this author (and one by the co-author), addresses the neglected areas of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces. Topics are covered in a comprehensive fashion, with homogeneous presentation for the benefit of the reader. The contributors address the economic aspects of biosensors and incorporate coverage of biosensor fabrication and nanobiosensors, among other topics. The comments, comparison, and discussion presented provides a better perspective of where the field of biosensors is heading. Serves as a comprehensive resource on biosensor analysis Examines timely topics such as biosensor fabrication and nanobiosensors Covers economic aspects and medical applications (e.g., the role of analytes in controlling diabetes)

Functional Materials and Nanotechnology

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Publisher : Trans Tech Publications Ltd
ISBN 13 : 3038138134
Total Pages : 560 pages
Book Rating : 4.0/5 (381 download)

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Book Synopsis Functional Materials and Nanotechnology by : B. Xu

Download or read book Functional Materials and Nanotechnology written by B. Xu and published by Trans Tech Publications Ltd. This book was released on 2012-03-27 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume is indexed by Thomson Reuters CPCI-S (WoS). These are the proceedings of the International Conference on Functional Materials and Nanotechnology (FMN2012), held on the 19 and 20th May, 2012, in Zhengzhou, P.R. China. They focus on Functional Materials and Nanotechnology. The peer-reviewed papers are divided into Chapter 1: Advanced Materials Engineering and Nanotechnology; Chapter 2: Nanotechnology, Mechanics and Materials Science; Chapter 3: Materials Applications, Green Chemistry and Mining Engineering; Chapter 4: Materials, Biotechnology, Manufacturing Engineering and Environment.

Engineering Biosensors

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Publisher : Academic Press
ISBN 13 : 0080523633
Total Pages : 404 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Engineering Biosensors by : Ajit Sadana

Download or read book Engineering Biosensors written by Ajit Sadana and published by Academic Press. This book was released on 2001-10-04 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensors are becoming increasingly important bioanalytical tools in the pharmaceutical, biotechnology, food, and other consumer oriented industries. The technology, though well developed in Europe, is slowly developing and has begun to generate interest in the United States only over the past couple of years. Research is now being directed toward the development of biosensors that are versatile, economical, and simple to use. Engineering Biosensors is a comprehensive introduction to biosensors that includes numerous illustrations to further explain the main concepts and practical examples from existing literature. It describes what biosensors are, where they are used, and how their performance is affected by existing surface characteristics. A better understanding of biosensors, as provided by this book, will greatly assist in the design of new as well as the improvement of existing biosensors. Readers are also provided with invaluable and hard-to-find data on the economics of the biosensor market to assist them in better understanding the market and where it is heading.

Fractal Analysis of Binding and Dissociation Kinetics of Thrombin on Biosensor Surfaces

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (129 download)

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Book Synopsis Fractal Analysis of Binding and Dissociation Kinetics of Thrombin on Biosensor Surfaces by : Atul M. Doke

Download or read book Fractal Analysis of Binding and Dissociation Kinetics of Thrombin on Biosensor Surfaces written by Atul M. Doke and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dekker Encyclopedia of Nanoscience and Nanotechnology

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Publisher : CRC Press
ISBN 13 : 9780824750480
Total Pages : 1006 pages
Book Rating : 4.7/5 (54 download)

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Book Synopsis Dekker Encyclopedia of Nanoscience and Nanotechnology by : James A. Schwarz

Download or read book Dekker Encyclopedia of Nanoscience and Nanotechnology written by James A. Schwarz and published by CRC Press. This book was released on 2004 with total page 1006 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sensor Systems for Biological Agent Attacks

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Publisher : National Academies Press
ISBN 13 : 030909576X
Total Pages : 209 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Sensor Systems for Biological Agent Attacks by : National Research Council

Download or read book Sensor Systems for Biological Agent Attacks written by National Research Council and published by National Academies Press. This book was released on 2005-12-11 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last ten years, there has been growing concern about potential biological attacks on the nation's population and its military facilities. It is now possible to detect such attacks quickly enough to permit treatment of potential victims prior to the onset of symptoms. The capability to "detect to warn", that is in time to take action to minimize human exposure, however, is still lacking. To help achieve such a capability, the Defense Threat Reduction Agency (DTRA) asked the National Research Council (NRC) to assess the development path for "detect to warn" sensors systems. This report presents the results of this assessment including analysis of scenarios for protecting facilities, sensor requirements, and detection technologies and systems. Findings and recommendations are provided for the most probable path to achieve a detect-to-warn capability and potential technological breakthroughs that could accelerate its attainment.

Biomarkers and Biosensors

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Publisher : Newnes
ISBN 13 : 0444537953
Total Pages : 702 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Biomarkers and Biosensors by : Ajit Sadana

Download or read book Biomarkers and Biosensors written by Ajit Sadana and published by Newnes. This book was released on 2014-12-08 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers and Biosensors offers thorough coverage of biomarker/biosensor interaction, current research trends, and future developments in applications of drug discovery. This book is useful to researchers in this field as well as clinicians interested in new developments in early detection and diagnosis of disease or the mode of operation of biomarkers. Biomarkers and Biosensors also emphasizes kinetics, and clearly delineates how this influences the biomarker market. Offers thorough coverage of the kinetics of biomarker interaction with the biosensor surface Provides evidence-based approach to evaluate effectiveness Provides pharmaceutical chemists the possibilities and methodology in assessing the effectiveness of new drugs Provides the information needed for the selection of the best biomarker for a specific application

Assay Development

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Publisher : John Wiley & Sons
ISBN 13 : 0470191155
Total Pages : 450 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Assay Development by : Ge Wu

Download or read book Assay Development written by Ge Wu and published by John Wiley & Sons. This book was released on 2010-04-26 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential principles and practice of assay development The first comprehensive, integrated treatment of the subject, Assay Development: Fundamentals and Practices covers the essentials and techniques involved in carrying out an assay project in either a biotechnology/drug discovery setting or a platform setting. Rather than attempting comprehensive coverage of all assay development technologies, the book introduces the most widely used assay development technologies and illustrates the art of assay development through a few commonly encountered biological targets in assay development (e.g., proteases, kinases, ion channels, and G protein-coupled receptors). Just enough biological background for these biological targets is provided so that the reader can follow the logics of assay development. Chapters discuss: The basics of assay development, including foundational concepts and applications Commonly used instrumental methods for both biochemical assays and cell-based assays Assay strategies for protein binding and enzymatic activity Cell-based assays High-throughput screening An in-depth study of the now popular Caliper's off-chip kinase assay provides an instructive, real-world example of the assay development process.

Methods for Affinity-Based Separations of Enzymes and Proteins

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Publisher : Springer Science & Business Media
ISBN 13 : 9783764363055
Total Pages : 240 pages
Book Rating : 4.3/5 (63 download)

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Book Synopsis Methods for Affinity-Based Separations of Enzymes and Proteins by : Munishwar N. Gupta

Download or read book Methods for Affinity-Based Separations of Enzymes and Proteins written by Munishwar N. Gupta and published by Springer Science & Business Media. This book was released on 2002-04-01 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: One major concern of biotechnology is either using enzymes or producing them. Enzyme/protein production is therefore an important starting point for biotechnology. Bioseparation or Downstream Processing constitutes about 40-90% of the total production cost. Driven by economics, highly selective technologies applicable to large-scale processing have emerged during the last decade. These technologies are slowly diffusing to enzymologists who are working on a smaller scale, looking for fast and efficient purification protocols. The affinity-based techniques (including precipitation, two-phase extractions, expanded bed chromatography, perfusion chromatography and monoliths) described in this volume provide current and new cutting-edge methods. Consequently, the book is of main interest to researchers in biochemistry, biochemical engineering and biotechnology, working either in academic or industrial sectors.

Encyclopedia of Surface and Colloid Science

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Publisher : CRC Press
ISBN 13 : 9780849396076
Total Pages : 962 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Encyclopedia of Surface and Colloid Science by : P. Somasundaran

Download or read book Encyclopedia of Surface and Colloid Science written by P. Somasundaran and published by CRC Press. This book was released on 2006 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt: