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Author : Anand K. Gavai.
Publisher :
ISBN 13 : 9789085853909
Total Pages : 98 pages
Book Rating : 4.8/5 (539 download)
Download or read book Bayesian Networks for Omics Data Analysis written by Anand K. Gavai. and published by . This book was released on 2009 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kim-Anh Do
Publisher : Cambridge University Press
ISBN 13 : 052186092X
Total Pages : 437 pages
Book Rating : 4.5/5 (218 download)
Download or read book Bayesian Inference for Gene Expression and Proteomics written by Kim-Anh Do and published by Cambridge University Press. This book was released on 2006-07-24 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert overviews of Bayesian methodology, tools and software for multi-platform high-throughput experimentation.
Author : Bani K. Mallick
Publisher : John Wiley & Sons
ISBN 13 : 9780470742815
Total Pages : 252 pages
Book Rating : 4.7/5 (428 download)
Download or read book Bayesian Analysis of Gene Expression Data written by Bani K. Mallick and published by John Wiley & Sons. This book was released on 2009-07-20 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of high-throughput genetic experimentation is evolving rapidly, with the advent of new technologies and new venues for data mining. Bayesian methods play a role central to the future of data and knowledge integration in the field of Bioinformatics. This book is devoted exclusively to Bayesian methods of analysis for applications to high-throughput gene expression data, exploring the relevant methods that are changing Bioinformatics. Case studies, illustrating Bayesian analyses of public gene expression data, provide the backdrop for students to develop analytical skills, while the more experienced readers will find the review of advanced methods challenging and attainable. This book: Introduces the fundamentals in Bayesian methods of analysis for applications to high-throughput gene expression data. Provides an extensive review of Bayesian analysis and advanced topics for Bioinformatics, including examples that extensively detail the necessary applications. Accompanied by website featuring datasets, exercises and solutions. Bayesian Analysis of Gene Expression Data offers a unique introduction to both Bayesian analysis and gene expression, aimed at graduate students in Statistics, Biomedical Engineers, Computer Scientists, Biostatisticians, Statistical Geneticists, Computational Biologists, applied Mathematicians and Medical consultants working in genomics. Bioinformatics researchers from many fields will find much value in this book.
Author : Richard E. Neapolitan
Publisher : Morgan Kaufmann
ISBN 13 : 0080919367
Total Pages : 421 pages
Book Rating : 4.0/5 (89 download)
Download or read book Probabilistic Methods for Bioinformatics written by Richard E. Neapolitan and published by Morgan Kaufmann. This book was released on 2009-06-12 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Bayesian network is one of the most important architectures for representing and reasoning with multivariate probability distributions. When used in conjunction with specialized informatics, possibilities of real-world applications are achieved. Probabilistic Methods for BioInformatics explains the application of probability and statistics, in particular Bayesian networks, to genetics. This book provides background material on probability, statistics, and genetics, and then moves on to discuss Bayesian networks and applications to bioinformatics. Rather than getting bogged down in proofs and algorithms, probabilistic methods used for biological information and Bayesian networks are explained in an accessible way using applications and case studies. The many useful applications of Bayesian networks that have been developed in the past 10 years are discussed. Forming a review of all the significant work in the field that will arguably become the most prevalent method in biological data analysis. Unique coverage of probabilistic reasoning methods applied to bioinformatics data--those methods that are likely to become the standard analysis tools for bioinformatics. Shares insights about when and why probabilistic methods can and cannot be used effectively; Complete review of Bayesian networks and probabilistic methods with a practical approach.
Author : Mittal, Ankush
Publisher : IGI Global
ISBN 13 : 159904143X
Total Pages : 368 pages
Book Rating : 4.5/5 (99 download)
Download or read book Bayesian Network Technologies: Applications and Graphical Models written by Mittal, Ankush and published by IGI Global. This book was released on 2007-03-31 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book provides an excellent, well-balanced collection of areas where Bayesian networks have been successfully applied; it describes the underlying concepts of Bayesian Networks with the help of diverse applications, and theories that prove Bayesian networks valid"--Provided by publisher.
Author : Dipak K. Dey
Publisher : CRC Press
ISBN 13 : 1420070185
Total Pages : 466 pages
Book Rating : 4.4/5 (2 download)
Download or read book Bayesian Modeling in Bioinformatics written by Dipak K. Dey and published by CRC Press. This book was released on 2010-09-03 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian Modeling in Bioinformatics discusses the development and application of Bayesian statistical methods for the analysis of high-throughput bioinformatics data arising from problems in molecular and structural biology and disease-related medical research, such as cancer. It presents a broad overview of statistical inference, clustering, and c
Author : Olivier Pourret
Publisher : John Wiley & Sons
ISBN 13 : 9780470994542
Total Pages : 446 pages
Book Rating : 4.9/5 (945 download)
Download or read book Bayesian Networks written by Olivier Pourret and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian Networks, the result of the convergence of artificial intelligence with statistics, are growing in popularity. Their versatility and modelling power is now employed across a variety of fields for the purposes of analysis, simulation, prediction and diagnosis. This book provides a general introduction to Bayesian networks, defining and illustrating the basic concepts with pedagogical examples and twenty real-life case studies drawn from a range of fields including medicine, computing, natural sciences and engineering. Designed to help analysts, engineers, scientists and professionals taking part in complex decision processes to successfully implement Bayesian networks, this book equips readers with proven methods to generate, calibrate, evaluate and validate Bayesian networks. The book: Provides the tools to overcome common practical challenges such as the treatment of missing input data, interaction with experts and decision makers, determination of the optimal granularity and size of the model. Highlights the strengths of Bayesian networks whilst also presenting a discussion of their limitations. Compares Bayesian networks with other modelling techniques such as neural networks, fuzzy logic and fault trees. Describes, for ease of comparison, the main features of the major Bayesian network software packages: Netica, Hugin, Elvira and Discoverer, from the point of view of the user. Offers a historical perspective on the subject and analyses future directions for research. Written by leading experts with practical experience of applying Bayesian networks in finance, banking, medicine, robotics, civil engineering, geology, geography, genetics, forensic science, ecology, and industry, the book has much to offer both practitioners and researchers involved in statistical analysis or modelling in any of these fields.
Author : George Tseng
Publisher : Cambridge University Press
ISBN 13 : 1107069114
Total Pages : 497 pages
Book Rating : 4.1/5 (7 download)
Download or read book Integrating Omics Data written by George Tseng and published by Cambridge University Press. This book was released on 2015-09-23 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tutorial chapters by leaders in the field introduce state-of-the-art methods to handle information integration problems of omics data.
Author : Momiao Xiong
Publisher : CRC Press
ISBN 13 : 135117262X
Total Pages : 580 pages
Book Rating : 4.3/5 (511 download)
Download or read book Big Data in Omics and Imaging written by Momiao Xiong and published by CRC Press. This book was released on 2018-06-14 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Big Data in Omics and Imaging: Integrated Analysis and Causal Inference addresses the recent development of integrated genomic, epigenomic and imaging data analysis and causal inference in big data era. Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), genome-wide expression studies (GWES), and epigenome-wide association studies (EWAS), the overall contribution of the new identified genetic variants is small and a large fraction of genetic variants is still hidden. Understanding the etiology and causal chain of mechanism underlying complex diseases remains elusive. It is time to bring big data, machine learning and causal revolution to developing a new generation of genetic analysis for shifting the current paradigm of genetic analysis from shallow association analysis to deep causal inference and from genetic analysis alone to integrated omics and imaging data analysis for unraveling the mechanism of complex diseases. FEATURES Provides a natural extension and companion volume to Big Data in Omic and Imaging: Association Analysis, but can be read independently. Introduce causal inference theory to genomic, epigenomic and imaging data analysis Develop novel statistics for genome-wide causation studies and epigenome-wide causation studies. Bridge the gap between the traditional association analysis and modern causation analysis Use combinatorial optimization methods and various causal models as a general framework for inferring multilevel omic and image causal networks Present statistical methods and computational algorithms for searching causal paths from genetic variant to disease Develop causal machine learning methods integrating causal inference and machine learning Develop statistics for testing significant difference in directed edge, path, and graphs, and for assessing causal relationships between two networks The book is designed for graduate students and researchers in genomics, epigenomics, medical image, bioinformatics, and data science. Topics covered are: mathematical formulation of causal inference, information geometry for causal inference, topology group and Haar measure, additive noise models, distance correlation, multivariate causal inference and causal networks, dynamic causal networks, multivariate and functional structural equation models, mixed structural equation models, causal inference with confounders, integer programming, deep learning and differential equations for wearable computing, genetic analysis of function-valued traits, RNA-seq data analysis, causal networks for genetic methylation analysis, gene expression and methylation deconvolution, cell –specific causal networks, deep learning for image segmentation and image analysis, imaging and genomic data analysis, integrated multilevel causal genomic, epigenomic and imaging data analysis.
Author : Radhakrishnan Nagarajan
Publisher : Springer Science & Business Media
ISBN 13 : 1461464463
Total Pages : 168 pages
Book Rating : 4.4/5 (614 download)
Download or read book Bayesian Networks in R written by Radhakrishnan Nagarajan and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian Networks in R with Applications in Systems Biology is unique as it introduces the reader to the essential concepts in Bayesian network modeling and inference in conjunction with examples in the open-source statistical environment R. The level of sophistication is also gradually increased across the chapters with exercises and solutions for enhanced understanding for hands-on experimentation of the theory and concepts. The application focuses on systems biology with emphasis on modeling pathways and signaling mechanisms from high-throughput molecular data. Bayesian networks have proven to be especially useful abstractions in this regard. Their usefulness is especially exemplified by their ability to discover new associations in addition to validating known ones across the molecules of interest. It is also expected that the prevalence of publicly available high-throughput biological data sets may encourage the audience to explore investigating novel paradigms using the approaches presented in the book.
Author : Marco Scutari
Publisher : CRC Press
ISBN 13 : 1482225581
Total Pages : 243 pages
Book Rating : 4.4/5 (822 download)
Download or read book Bayesian Networks written by Marco Scutari and published by CRC Press. This book was released on 2014-06-20 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand the Foundations of Bayesian Networks—Core Properties and Definitions Explained Bayesian Networks: With Examples in R introduces Bayesian networks using a hands-on approach. Simple yet meaningful examples in R illustrate each step of the modeling process. The examples start from the simplest notions and gradually increase in complexity. The authors also distinguish the probabilistic models from their estimation with data sets. The first three chapters explain the whole process of Bayesian network modeling, from structure learning to parameter learning to inference. These chapters cover discrete Bayesian, Gaussian Bayesian, and hybrid networks, including arbitrary random variables. The book then gives a concise but rigorous treatment of the fundamentals of Bayesian networks and offers an introduction to causal Bayesian networks. It also presents an overview of R and other software packages appropriate for Bayesian networks. The final chapter evaluates two real-world examples: a landmark causal protein signaling network paper and graphical modeling approaches for predicting the composition of different body parts. Suitable for graduate students and non-statisticians, this text provides an introductory overview of Bayesian networks. It gives readers a clear, practical understanding of the general approach and steps involved.
Author : Giulio D'Agostini
Publisher : World Scientific
ISBN 13 : 981277551X
Total Pages : 351 pages
Book Rating : 4.8/5 (127 download)
Download or read book Bayesian Reasoning in Data Analysis written by Giulio D'Agostini and published by World Scientific. This book was released on 2003 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a multi-level introduction to Bayesian reasoning (as opposed to OC conventional statisticsOCO) and its applications to data analysis. The basic ideas of this OC newOCO approach to the quantification of uncertainty are presented using examples from research and everyday life. Applications covered include: parametric inference; combination of results; treatment of uncertainty due to systematic errors and background; comparison of hypotheses; unfolding of experimental distributions; upper/lower bounds in frontier-type measurements. Approximate methods for routine use are derived and are shown often to coincide OCo under well-defined assumptions! OCo with OC standardOCO methods, which can therefore be seen as special cases of the more general Bayesian methods. In dealing with uncertainty in measurements, modern metrological ideas are utilized, including the ISO classification of uncertainty into type A and type B. These are shown to fit well into the Bayesian framework.
Author : Ornella Cominetti
Publisher : Frontiers Media SA
ISBN 13 : 2832523420
Total Pages : 184 pages
Book Rating : 4.8/5 (325 download)
Download or read book Advances in methods and tools for multi-omics data analysis written by Ornella Cominetti and published by Frontiers Media SA. This book was released on 2023-05-12 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Monidipa Das
Publisher : Springer Nature
ISBN 13 : 3030277496
Total Pages : 149 pages
Book Rating : 4.0/5 (32 download)
Download or read book Enhanced Bayesian Network Models for Spatial Time Series Prediction written by Monidipa Das and published by Springer Nature. This book was released on 2019-11-07 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research monograph is highly contextual in the present era of spatial/spatio-temporal data explosion. The overall text contains many interesting results that are worth applying in practice, while it is also a source of intriguing and motivating questions for advanced research on spatial data science. The monograph is primarily prepared for graduate students of Computer Science, who wish to employ probabilistic graphical models, especially Bayesian networks (BNs), for applied research on spatial/spatio-temporal data. Students of any other discipline of engineering, science, and technology, will also find this monograph useful. Research students looking for a suitable problem for their MS or PhD thesis will also find this monograph beneficial. The open research problems as discussed with sufficient references in Chapter-8 and Chapter-9 can immensely help graduate researchers to identify topics of their own choice. The various illustrations and proofs presented throughout the monograph may help them to better understand the working principles of the models. The present monograph, containing sufficient description of the parameter learning and inference generation process for each enhanced BN model, can also serve as an algorithmic cookbook for the relevant system developers.
Author : Franco Taroni
Publisher : John Wiley & Sons
ISBN 13 : 0470979739
Total Pages : 472 pages
Book Rating : 4.4/5 (79 download)
Download or read book Bayesian Networks for Probabilistic Inference and Decision Analysis in Forensic Science written by Franco Taroni and published by John Wiley & Sons. This book was released on 2014-09-22 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian Networks “This book should have a place on the bookshelf of every forensic scientist who cares about the science of evidence interpretation.” Dr. Ian Evett, Principal Forensic Services Ltd, London, UK Bayesian Networks for Probabilistic Inference and Decision Analysis in Forensic Science Second Edition Continuing developments in science and technology mean that the amounts of information forensic scientists are able to provide for criminal investigations is ever increasing. The commensurate increase in complexity creates diffculties for scientists and lawyers with regard to evaluation and interpretation, notably with respect to issues of inference and decision. Probability theory, implemented through graphical methods, and specifically Bayesian networks, provides powerful methods to deal with this complexity. Extensions of these methods to elements of decision theory provide further support and assistance to the judicial system. Bayesian Networks for Probabilistic Inference and Decision Analysis in Forensic Science provides a unique and comprehensive introduction to the use of Bayesian decision networks for the evaluation and interpretation of scientific findings in forensic science, and for the support of decision-makers in their scientific and legal tasks. Includes self-contained introductions to probability and decision theory. Develops the characteristics of Bayesian networks, object-oriented Bayesian networks and their extension to decision models. Features implementation of the methodology with reference to commercial and academically available software. Presents standard networks and their extensions that can be easily implemented and that can assist in the reader’s own analysis of real cases. Provides a technique for structuring problems and organizing data based on methods and principles of scientific reasoning. Contains a method for the construction of coherent and defensible arguments for the analysis and evaluation of scientific findings and for decisions based on them. Is written in a lucid style, suitable for forensic scientists and lawyers with minimal mathematical background. Includes a foreword by Ian Evett. The clear and accessible style of this second edition makes this book ideal for all forensic scientists, applied statisticians and graduate students wishing to evaluate forensic findings from the perspective of probability and decision analysis. It will also appeal to lawyers and other scientists and professionals interested in the evaluation and interpretation of forensic findings, including decision making based on scientific information.
Author : Momiao Xiong
Publisher : CRC Press
ISBN 13 : 1351172638
Total Pages : 736 pages
Book Rating : 4.3/5 (511 download)
Download or read book Big Data in Omics and Imaging written by Momiao Xiong and published by CRC Press. This book was released on 2018-06-14 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Big Data in Omics and Imaging: Integrated Analysis and Causal Inference addresses the recent development of integrated genomic, epigenomic and imaging data analysis and causal inference in big data era. Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), genome-wide expression studies (GWES), and epigenome-wide association studies (EWAS), the overall contribution of the new identified genetic variants is small and a large fraction of genetic variants is still hidden. Understanding the etiology and causal chain of mechanism underlying complex diseases remains elusive. It is time to bring big data, machine learning and causal revolution to developing a new generation of genetic analysis for shifting the current paradigm of genetic analysis from shallow association analysis to deep causal inference and from genetic analysis alone to integrated omics and imaging data analysis for unraveling the mechanism of complex diseases. FEATURES Provides a natural extension and companion volume to Big Data in Omic and Imaging: Association Analysis, but can be read independently. Introduce causal inference theory to genomic, epigenomic and imaging data analysis Develop novel statistics for genome-wide causation studies and epigenome-wide causation studies. Bridge the gap between the traditional association analysis and modern causation analysis Use combinatorial optimization methods and various causal models as a general framework for inferring multilevel omic and image causal networks Present statistical methods and computational algorithms for searching causal paths from genetic variant to disease Develop causal machine learning methods integrating causal inference and machine learning Develop statistics for testing significant difference in directed edge, path, and graphs, and for assessing causal relationships between two networks The book is designed for graduate students and researchers in genomics, epigenomics, medical image, bioinformatics, and data science. Topics covered are: mathematical formulation of causal inference, information geometry for causal inference, topology group and Haar measure, additive noise models, distance correlation, multivariate causal inference and causal networks, dynamic causal networks, multivariate and functional structural equation models, mixed structural equation models, causal inference with confounders, integer programming, deep learning and differential equations for wearable computing, genetic analysis of function-valued traits, RNA-seq data analysis, causal networks for genetic methylation analysis, gene expression and methylation deconvolution, cell –specific causal networks, deep learning for image segmentation and image analysis, imaging and genomic data analysis, integrated multilevel causal genomic, epigenomic and imaging data analysis.
Author : Henry Horng-Shing Lu
Publisher : Springer Nature
ISBN 13 : 3662659026
Total Pages : 406 pages
Book Rating : 4.6/5 (626 download)
Download or read book Handbook of Statistical Bioinformatics written by Henry Horng-Shing Lu and published by Springer Nature. This book was released on 2022-12-08 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, this handbook collects authoritative contributions on modern methods and tools in statistical bioinformatics with a focus on the interface between computational statistics and cutting-edge developments in computational biology. The three parts of the book cover statistical methods for single-cell analysis, network analysis, and systems biology, with contributions by leading experts addressing key topics in probabilistic and statistical modeling and the analysis of massive data sets generated by modern biotechnology. This handbook will serve as a useful reference source for students, researchers and practitioners in statistics, computer science and biological and biomedical research, who are interested in the latest developments in computational statistics as applied to computational biology.
