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Bayesian Approaches For Instrumental Variable Analysis With Censored Time To Event Outcome
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Book Synopsis Bayesian Approaches for Instrumental Variable Analysis with Censored Time-to-event Outcome by : Xuyang Lu
Download or read book Bayesian Approaches for Instrumental Variable Analysis with Censored Time-to-event Outcome written by Xuyang Lu and published by . This book was released on 2014 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: The method of instrumental variable (IV) analysis has been widely used in economics, epidemiology, and other fields to estimate the causal effects of intermediate covariates on outcomes, in the presence of unobserved confounders and/or measurement errors in covariates. Consistent estimation of the effect has been developed when the outcome is continuous, while methods for binary outcome produce inconsistent estimation. In this dissertation, we examine two IV methods in the literature for binary outcome and show the bias in parameter estimate by a simulation study. The identifiability problem of IV analysis with binary outcome is discussed. Moreover, IV methods for time-to-event outcome with censored data remain underdeveloped. We propose two Bayesian approaches for IV analysis with censored time-to-event outcome by using a two-stage linear model: One is a parametric Bayesian model with normal and non-normal elliptically contoured error distributions, and the other is a semiparametric Bayesian model with Dirichlet process mixtures for the random errors, in order to relax the parametric assumptions and address heterogeneous clustering problems. Markov Chain Monte Carlo sampling methods are developed for both parametric and semiparametric Bayesian models to estimate the endogenous parameter. Performance of our methods is examined by simulation studies. Both methods largely reduce bias in estimation and greatly improve coverage probability of the endogenous parameter, compared to the regular method where the unobserved confounders and/or measurement errors are ignored. We illustrate our methods on the Women's Health Initiative Observational Study and the Atherosclerosis Risk in Communities Study.
Book Synopsis Objective Bayesian Variable Selection for Censored Data by : Silvia Perra
Download or read book Objective Bayesian Variable Selection for Censored Data written by Silvia Perra and published by LAP Lambert Academic Publishing. This book was released on 2013 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of survival analysis is to explain and predict the survival, usually defined along the time domain. In this work we study it by means of regression models. In statistical data analysis it is common to consider the regression set up in which a given response variable depends on some factors and/or covariates. The model selection problem mainly consists in choosing the covariates which better explain the dependent variable in a precise and hopefully fast manner. This process usually has several steps: the first one is to collect considerations from an expert about the set of covariates, then the statistician derives a prior on model parameters and constructs a tool to solve the model selection problem. We consider the model selection problem in survival analysis when the response variable is the time to event. Under an objective Bayesian approach, some commonly used tools in literature are the Intrinsic Bayes factor (IBF) and the Fractional Bayes factor (FBF). In this thesis we deal with the variable selection problem for censored data.
Book Synopsis Bayesian Method of Moments by : Arnold Zellner
Download or read book Bayesian Method of Moments written by Arnold Zellner and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Generalized Bayesian Instrumental Variable Approach Under Student T-Distributed Errors with Application by : Matthew Jude Salois
Download or read book A Generalized Bayesian Instrumental Variable Approach Under Student T-Distributed Errors with Application written by Matthew Jude Salois and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian analysis is given of an instrumental variable model that allows for t-distributed errors in both the structural equation and the instrument equation. Specifically, the approach for dealing with t-distributed errors is extended to the Bayesian instrumental variable estimator by modelling the variance for each error using a Gamma distributed hierarchical prior. The computation is carried out by using a Markov chain Monte Carlo sampling algorithm for the heteroskedastic case. An example using data illustrates the approach and shows that ignoring the presence of error terms with heavy tails in the instrument equation when it exists may lead to biased estimates.
Book Synopsis Flexible Imputation of Missing Data, Second Edition by : Stef van Buuren
Download or read book Flexible Imputation of Missing Data, Second Edition written by Stef van Buuren and published by CRC Press. This book was released on 2018-07-17 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Missing data pose challenges to real-life data analysis. Simple ad-hoc fixes, like deletion or mean imputation, only work under highly restrictive conditions, which are often not met in practice. Multiple imputation replaces each missing value by multiple plausible values. The variability between these replacements reflects our ignorance of the true (but missing) value. Each of the completed data set is then analyzed by standard methods, and the results are pooled to obtain unbiased estimates with correct confidence intervals. Multiple imputation is a general approach that also inspires novel solutions to old problems by reformulating the task at hand as a missing-data problem. This is the second edition of a popular book on multiple imputation, focused on explaining the application of methods through detailed worked examples using the MICE package as developed by the author. This new edition incorporates the recent developments in this fast-moving field. This class-tested book avoids mathematical and technical details as much as possible: formulas are accompanied by verbal statements that explain the formula in accessible terms. The book sharpens the reader’s intuition on how to think about missing data, and provides all the tools needed to execute a well-grounded quantitative analysis in the presence of missing data.
Book Synopsis Bayesian and Classical Approaches to Instrumental Variable Regression by : F. R. Kleibergen
Download or read book Bayesian and Classical Approaches to Instrumental Variable Regression written by F. R. Kleibergen and published by . This book was released on 1998 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bayesian Analysis of Instrumental Variable Models by :
Download or read book Bayesian Analysis of Instrumental Variable Models written by and published by . This book was released on 2012 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Semi-Parametric Bayesian Approach to the Instrumental Variable Problem by : Timothy G. Conley
Download or read book A Semi-Parametric Bayesian Approach to the Instrumental Variable Problem written by Timothy G. Conley and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: We develop a Bayesian semi-parametric approach to the instrumental variable problem. We assume linear structural and reduced form equations, but model the error distributions non-parametrically. A Dirichlet process prior is used for the joint distribution of structural and instrumental variable equations errors. Our implementation of the Dirichlet process prior uses a normal distribution as a base model. It can therefore be interpreted as modeling the unknown joint distribution with a mixture of normal distributions with a variable number of mixture components. We demonstrate that this procedure is both feasible and sensible using actual and simulated data. Sampling experiments compare inferences from the non-parametric Bayesian procedure with those based on procedures from the recent literature on weak instrument asymptotics. When errors are non-normal, our procedure is more efficient than standard Bayesian or classical methods.
Book Synopsis Analysis of Observational Health Care Data Using SAS by : Douglas E. Faries
Download or read book Analysis of Observational Health Care Data Using SAS written by Douglas E. Faries and published by SAS Press. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book guides researchers in performing and presenting high-quality analyses of all kinds of non-randomized studies, including analyses of observational studies, claims database analyses, assessment of registry data, survey data, pharmaco-economic data, and many more applications. The text is sufficiently detailed to provide not only general guidance, but to help the researcher through all of the standard issues that arise in such analyses. Just enough theory is included to allow the reader to understand the pros and cons of alternative approaches and when to use each method. The numerous contributors to this book illustrate, via real-world numerical examples and SAS code, appropriate implementations of alternative methods. The end result is that researchers will learn how to present high-quality and transparent analyses that will lead to fair and objective decisions from observational data. This book is part of the SAS Press program.
Book Synopsis Modeling Discrete Time-to-Event Data by : Gerhard Tutz
Download or read book Modeling Discrete Time-to-Event Data written by Gerhard Tutz and published by Springer. This book was released on 2016-06-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on statistical methods for the analysis of discrete failure times. Failure time analysis is one of the most important fields in statistical research, with applications affecting a wide range of disciplines, in particular, demography, econometrics, epidemiology and clinical research. Although there are a large variety of statistical methods for failure time analysis, many techniques are designed for failure times that are measured on a continuous scale. In empirical studies, however, failure times are often discrete, either because they have been measured in intervals (e.g., quarterly or yearly) or because they have been rounded or grouped. The book covers well-established methods like life-table analysis and discrete hazard regression models, but also introduces state-of-the art techniques for model evaluation, nonparametric estimation and variable selection. Throughout, the methods are illustrated by real life applications, and relationships to survival analysis in continuous time are explained. Each section includes a set of exercises on the respective topics. Various functions and tools for the analysis of discrete survival data are collected in the R package discSurv that accompanies the book.
Book Synopsis Bayesian Data Analysis, Third Edition by : Andrew Gelman
Download or read book Bayesian Data Analysis, Third Edition written by Andrew Gelman and published by CRC Press. This book was released on 2013-11-01 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition, this classic book is widely considered the leading text on Bayesian methods, lauded for its accessible, practical approach to analyzing data and solving research problems. Bayesian Data Analysis, Third Edition continues to take an applied approach to analysis using up-to-date Bayesian methods. The authors—all leaders in the statistics community—introduce basic concepts from a data-analytic perspective before presenting advanced methods. Throughout the text, numerous worked examples drawn from real applications and research emphasize the use of Bayesian inference in practice. New to the Third Edition Four new chapters on nonparametric modeling Coverage of weakly informative priors and boundary-avoiding priors Updated discussion of cross-validation and predictive information criteria Improved convergence monitoring and effective sample size calculations for iterative simulation Presentations of Hamiltonian Monte Carlo, variational Bayes, and expectation propagation New and revised software code The book can be used in three different ways. For undergraduate students, it introduces Bayesian inference starting from first principles. For graduate students, the text presents effective current approaches to Bayesian modeling and computation in statistics and related fields. For researchers, it provides an assortment of Bayesian methods in applied statistics. Additional materials, including data sets used in the examples, solutions to selected exercises, and software instructions, are available on the book’s web page.
Book Synopsis Survival Analysis by : John P. Klein
Download or read book Survival Analysis written by John P. Klein and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Making complex methods more accessible to applied researchers without an advanced mathematical background, the authors present the essence of new techniques available, as well as classical techniques, and apply them to data. Practical suggestions for implementing the various methods are set off in a series of practical notes at the end of each section, while technical details of the derivation of the techniques are sketched in the technical notes. This book will thus be useful for investigators who need to analyse censored or truncated life time data, and as a textbook for a graduate course in survival analysis, the only prerequisite being a standard course in statistical methodology.
Book Synopsis The Prevention and Treatment of Missing Data in Clinical Trials by : National Research Council
Download or read book The Prevention and Treatment of Missing Data in Clinical Trials written by National Research Council and published by National Academies Press. This book was released on 2010-12-21 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.
Book Synopsis Joint Models for Longitudinal and Time-to-Event Data by : Dimitris Rizopoulos
Download or read book Joint Models for Longitudinal and Time-to-Event Data written by Dimitris Rizopoulos and published by CRC Press. This book was released on 2012-06-22 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: In longitudinal studies it is often of interest to investigate how a marker that is repeatedly measured in time is associated with a time to an event of interest, e.g., prostate cancer studies where longitudinal PSA level measurements are collected in conjunction with the time-to-recurrence. Joint Models for Longitudinal and Time-to-Event Data: With Applications in R provides a full treatment of random effects joint models for longitudinal and time-to-event outcomes that can be utilized to analyze such data. The content is primarily explanatory, focusing on applications of joint modeling, but sufficient mathematical details are provided to facilitate understanding of the key features of these models. All illustrations put forward can be implemented in the R programming language via the freely available package JM written by the author. All the R code used in the book is available at: http://jmr.r-forge.r-project.org/
Book Synopsis The Frailty Model by : Luc Duchateau
Download or read book The Frailty Model written by Luc Duchateau and published by Springer Science & Business Media. This book was released on 2007-10-23 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Readers will find in the pages of this book a treatment of the statistical analysis of clustered survival data. Such data are encountered in many scientific disciplines including human and veterinary medicine, biology, epidemiology, public health and demography. A typical example is the time to death in cancer patients, with patients clustered in hospitals. Frailty models provide a powerful tool to analyze clustered survival data. In this book different methods based on the frailty model are described and it is demonstrated how they can be used to analyze clustered survival data. All programs used for these examples are available on the Springer website.
Book Synopsis Journal of the American Statistical Association by :
Download or read book Journal of the American Statistical Association written by and published by . This book was released on 2007 with total page 1542 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fundamentals of Nonparametric Bayesian Inference by : Subhashis Ghosal
Download or read book Fundamentals of Nonparametric Bayesian Inference written by Subhashis Ghosal and published by Cambridge University Press. This book was released on 2017-06-26 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explosive growth in computing power has made Bayesian methods for infinite-dimensional models - Bayesian nonparametrics - a nearly universal framework for inference, finding practical use in numerous subject areas. Written by leading researchers, this authoritative text draws on theoretical advances of the past twenty years to synthesize all aspects of Bayesian nonparametrics, from prior construction to computation and large sample behavior of posteriors. Because understanding the behavior of posteriors is critical to selecting priors that work, the large sample theory is developed systematically, illustrated by various examples of model and prior combinations. Precise sufficient conditions are given, with complete proofs, that ensure desirable posterior properties and behavior. Each chapter ends with historical notes and numerous exercises to deepen and consolidate the reader's understanding, making the book valuable for both graduate students and researchers in statistics and machine learning, as well as in application areas such as econometrics and biostatistics.
