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Basic Principles In Nucleic Acid Chemistry In The Beginning
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Book Synopsis Basic Principles in Nucleic Acid Chemistry V1 by : Paul O.P. Ts'o
Download or read book Basic Principles in Nucleic Acid Chemistry V1 written by Paul O.P. Ts'o and published by Elsevier. This book was released on 2012-12-02 with total page 651 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Principles in Nucleic Acid Chemistry, Volume I provides information pertinent to the fundamental aspects of nucleic acids. This book discusses the development of the basic principles in nucleic acid research that will serve as a foundation for further advancement in nucleic acid research. Organized into six chapters, this volume begins with an overview of the history of the scientific study of nucleic acid as a genetic material. This text then examines the utility of the analogs of the naturally occurring nucleic acid components as biochemical tools and as therapeutic agents. Other chapters consider mass spectrometry that deals with the production and chemistry of ions in the vapor phase. This book discusses as well the various aspects of the excited states of the nucleic acids. The final chapter deals with the systematic study of the physiochemical properties of the monomeric units of nucleic acid. This book is a valuable resource for molecular biologists, scientists, and research workers.
Book Synopsis Principles of Nucleic Acid Structure by : Wolfram Saenger
Download or read book Principles of Nucleic Acid Structure written by Wolfram Saenger and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical ther modynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the grad uate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses. CHARLES R. CANTOR New York Preface This monograph is based on a review on polynucleotide structures written for a book series in 1976.
Book Synopsis Basic Principles in Nucleic Acid Chemistry V2 by : Paul O.P. Ts'o
Download or read book Basic Principles in Nucleic Acid Chemistry V2 written by Paul O.P. Ts'o and published by Elsevier. This book was released on 2012-12-02 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Principles in Nuclear Acid Chemistry, Volume II presents the significant progress in nucleic acid research and its contribution and influence on various aspects of human life. This book contains five chapters and begins with the susceptibility of nucleic acids towards attack by chemical reagents whose reactions with polynucleotides have been studied. This topic is followed by a presentation of experimental techniques used to study the properties of nucleic acids. The following chapter discusses some basic features embodied in the polyribo- and poly-deoxyribonucleotide backbone chains; the possibility of rotation around backbone bonds in the ""random"" single-stranded form; and the short- and long-range interactions in idealized and real chains. This chapter also looks into the thermodynamic and polyelectrolyte aspects of nucleic acid behavior. A chapter describes the special features of the third class of DNA, namely, closed duplex DNA, in which covalent chain scissions are absent. The last chapter examines the intrinsic properties and the interaction of the dimers and oligomers, with special emphasis on the influence of the phosphodiester linkages on the conformation and interaction of these short segments of nucleic acids. This book is of great value to workers in biomedical research and to higher level biochemistry instructors.
Book Synopsis Basic Principles in Nucleic Acid Chemistry by : Paul On Pong Ts'o
Download or read book Basic Principles in Nucleic Acid Chemistry written by Paul On Pong Ts'o and published by . This book was released on 1974 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nucleic Acids in Chemistry and Biology by : G. Michael Blackburn
Download or read book Nucleic Acids in Chemistry and Biology written by G. Michael Blackburn and published by Oxford University Press, USA. This book was released on 1996 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of the DNA double helix in 1953, nucleic acids have formed the central theme of much of contemporary molecular science. Recent mastery of nucleic acids synthesis has been the key to the establishment of the biotechnology industry, and our improving knowledge of nucleic acid structures and interactions is considerably influencing the design of novel drugs. The first edition of this book responded to the pressing need for a single volume that integrated the chemistry and biology of the nucleic acids in an introductory yet authoritative text. This second and completely updated edition, which includes a new chapter on techniques applied to nucleic acids, sets the basics of the nucleic acids in the context of the expanding horizons set by modern structural biology, RNA enzymology, drug discovery and biotechnology.
Book Synopsis Recombinant DNA Principles and Methodologies by : James Greene
Download or read book Recombinant DNA Principles and Methodologies written by James Greene and published by CRC Press. This book was released on 1998-06-25 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive yet balanced work emphasizes the principles and rationale underlying recombinant DNA methodology while furnishing a general understanding of the experimental protocols-suggesting flexible approaches to resolving particular molecular necessities that are easily adaptable to readers' specific applications. Features summary tables presenting at-a-glance information on practices of recombinant DNA methodologies! Recombinant DNA Principles and Methodologies discusses basic and advanced topics requisite to the employment of recombinant DNA technology, such as plasmid biology nucleic acid biochemistry restriction enzymes cloning strategies gel electrophoresis southern and northern blotting preparation of probes phage lambda biology cosmids and genome analysis cloned gene expression polymerase chain reaction conventional and automated DNA sequencing site-directed mutagenesis and more! Elucidating the material with over 2250 edifying references, equations, drawings, and photographs, this state-of-the-art resource is a valuable hands-on guide for molecular and cell biologists, biochemists, bioprocess technologists, applied and industrial microbiologists, virologists, geneticists, chemical engineers, and upper-level undergraduate and graduate students in these disciplines.
Book Synopsis Reflections on Biochemistry by : A. Kornberg
Download or read book Reflections on Biochemistry written by A. Kornberg and published by Elsevier. This book was released on 2014-05-18 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflections on Biochemistry: In Honour of Severo Ochoa offers reflections on a wide range of topics relating to biochemistry, including energy metabolism, lipids and saccharides, regulation, nucleic acids and the genetic code, protein biosynthesis, and cell biology. The essays celebrate Severo Ochoa's outstanding contributions to biochemistry spanning nearly half a century. This book is comprised of 47 chapters and begins with a biography of Ochoa and his scientific work in the field of biochemistry, particularly his research on intermediary metabolism, RNA synthesis, and the genetic code. The discussion then turns to energy metabolism, photosynthesis, and fermentation, touching on topics such as the role of lactic acid in the development of biochemistry and the biosynthesis of cell components from acetate. The next section is devoted to lipids, saccharides, and cell walls and includes chapters that deal with biotin, sulfur biochemistry, and dipicolinic acid. Subsequent chapters explore hormonal regulation of adipose tissue lipolysis; the structural relationship between genes and enzymes; bacteriophages, colicins, and ribosomes; and cell biology and neurobiology. This monograph will be of interest to biochemists and students of biochemistry.
Book Synopsis Applications of Infrared, Raman, and Resonance Raman Spectroscopy in Biochemistry by : Frank S. Parker
Download or read book Applications of Infrared, Raman, and Resonance Raman Spectroscopy in Biochemistry written by Frank S. Parker and published by Springer Science & Business Media. This book was released on 1983-10-01 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advanced Organic Chemistry of Nucleic Acids by : Zoe A. Shabarova
Download or read book Advanced Organic Chemistry of Nucleic Acids written by Zoe A. Shabarova and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequencing, cloning, transcription - these are but a few key techniques behind the current breathtaking advances in molecular biology and biochemistry. As these methods continuosly diversify, biochemists need a sound chemical understanding to keep the pace. Chemists beginning working in the molecular biology lab need an introduction to this field from their point of view. This book serves both: it describes most of the known chemical reactions of nucleosides, nucleotides, and nucleic acids in sufficient detail to provide the desired background, and additionally, the fundamental relations between sequence, structure and functionality of nucleic acids are presented. The first edition of this book, which was published in Russian, has immediately become a recognized standard reference. This second, thoroughly revised and updated edition, now published in English, is likely to achieve a similar position in the international scientific community.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Topics in Nucleic Acid Structure by : Stephen Neidle
Download or read book Topics in Nucleic Acid Structure written by Stephen Neidle and published by Springer. This book was released on 1981-06-18 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Structural Studies on Nucleic acids and Other Biopolymers by : J Duchesne
Download or read book Structural Studies on Nucleic acids and Other Biopolymers written by J Duchesne and published by Elsevier. This book was released on 2012-12-02 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physico-chemical Properties of Nucleic Acids, Volume II basically deals with the structural studies on nucleic acids and other biopolymers. This volume gives much emphasis on conformational changes using spectroscopic techniques and also on methods of thermodynamics and hydrodynamics. Volume II begins with Chapter 10 as continuation of Volume I and discusses the infrared and Raman spectroscopy of nucleic acids and polynucleotides. Chapter 11 delves further into the topic of infrared and Raman spectra particularly the vibrations in the base-residues. This volume also highlights the topic of RNA, where the structure of viral RNA and nuclear magnetic resonance studies of transfer RNAs in solution are covered. The last two chapters discuss the concept of thermodynamic and hydrodynamic properties of conformation transitions and changes. This volume caters to both students and researchers in various fields of science, such as biology, chemistry, molecular biology, biophysics, and microbiology.
Book Synopsis The Biochemistry of the Nucleic Acids by : R.L.P. Adams
Download or read book The Biochemistry of the Nucleic Acids written by R.L.P. Adams and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the first edition of this book was published in 1950, it predated the publication of the double-helical structure of DNA by three years. It is not, therefore, surprizing that nothing of the original book remains in the current edition. Indeed, such is the pace of change in the field of nucleic acids that less than 50% of material incorporated into the 1986 edition has been retained. The book aims at the advanced undergraduate and at graduates that are undertaking course work or requiring an in-depth background for their research. It also aims to provide the established scientist with a single text that permits updating across the whole field from DNA structure, replication and repair, through gene expression and its control to protein synthesis. Every chapter is accompanied by thorough referencing that enables the reader to evaluate personally the data and methodology that cannot be included in the text. In an attempt to keep this list within bounds, references are limited to about ten per page and, to accommodate the more recent literature, many of the older references have been left out in this latest edition.
Book Synopsis Photochemistry and Photobiology of Nucleic Acids by : Shih-Yi Wang
Download or read book Photochemistry and Photobiology of Nucleic Acids written by Shih-Yi Wang and published by Elsevier. This book was released on 2012-12-02 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photochemistry and Photobiology of Nucleic Acids, Volume I: Chemistry covers the historical developments in the study of photobiology and photochemistry of nucleic acid components. This volume is divided into 12 chapters that deal with the isolation and characterization of ultraviolet photoproducts of pyrimidines. After briefly covering the concepts of photochemistry of nucleic acids, this volume goes on describing the UV-induced physical and chemical alterations in nucleic acid components, such as pyrimidines, purines, their nucleosides and nucleotides, and related compounds. Significant chapters are devoted to mass and nuclear magnetic resonance spectrometry and crystal and molecular structure determinations by X-ray diffraction. Together with the pertinent examples, a short discussion on the theory and techniques is also presented in each chapter. This volume also includes a chapter on radiation chemistry to examine the close relationship between the chemical effects of UV-light and X- or gamma-radiation. This volume is of value to researchers who are active in the study of photochemistry and photobiology in nucleic acids as well as to advanced undergraduate and graduate students interested in this field.
Book Synopsis Nucleic Acid Structure by : W. Guschlbauer
Download or read book Nucleic Acid Structure written by W. Guschlbauer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teaching a course on nucleic acid structure is a hazardous undertaking, especially if one has no continuous teaching obligations. I still have done it on several occasions in various French universities, when colleagues, suffering from admin istrative overwork and excessive teaching obligations, had asked me to do so. This was generally done with a pile of notes and a dozen slides, and I always regretted that no small, concise, specialized book on nucleic acid structure for students at the senior or beginning graduate level ex isted. Every year, the lecture notes became more and more voluminous, with some key reprints intermingled. Everything changed when, in the spring of 1973, I re ceived an invitation to teach such a course, under the UNESCO-OAS-Molecular Biology Program at the Universi dad de Chile in Santiago during October 1973. I had ac cepted rather enthusiastically, but soon discovered that it would be necessary to produce a photocopied syllabus for the students. This was the fi rst premanuscript of this book. For nonscientific reasons, the course was first canceled and then postponed until December 1973. Nearly a year later, the course, in slightly amended form, was presented at the Lemonossow-State University in Moscow.
Book Synopsis Phosphorus NMR in Biology by : C. Burt
Download or read book Phosphorus NMR in Biology written by C. Burt and published by CRC Press. This book was released on 2018-01-18 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR is a technique that can spoil you. It is true that it is not as sensitive as some of the spectroscopic methods, but the quality of the information and the incredible ease of sample preparation make it one of the tools that have opened new vistas in biological research. This volume is intended to show how those vistas can range from the molecule to the microbe to man himself. Further, it is what prompts the rather broad title.
Book Synopsis Synthesis And Applications Of DNA And RNA by : Saran Narang
Download or read book Synthesis And Applications Of DNA And RNA written by Saran Narang and published by Elsevier. This book was released on 2012-12-02 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis and Applications of DNA and RNA discusses the significant contributions in the development of synthetic routes to DNA and RNA. This book contains nine chapters that describe the complexities in the chemistry and biology of DNA and RNA. After briefly dealing with the various stages of development in the chemical synthesis of polynucleotides, this book goes on presenting the DNA synthesis on solid supports and through the phosphoramidite method on silica supports. The discussions then shift to the chemical-enzymatic synthesis of expressed genes; the biochemical aspects of chemical syntheses of oligoribonucleotides; and the methods of rapid DNA and RNA sequence analysis. A chapter specifically tackles the protocols of DNA synthesis using double-stranded plasmid DNA as a template. The final chapter deals with the use of oligonucleotides for the identification and isolation of specific gene sequences. This chapter also covers the use oligonucleotides in the detection of human genetic diseases. Biologists, geneticists, and researchers interested in DNA and RNA synthesis will find this work invaluable.
