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Automated Objective Speech Markers For Differential Diagnosis Between Parkinsons Disease And Atypical Parkinsonian Disorders
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Book Synopsis Automated Objective Speech Markers for Differential Diagnosis Between Parkinson's Disease and Atypical Parkinsonian Disorders by : Biswajit Das
Download or read book Automated Objective Speech Markers for Differential Diagnosis Between Parkinson's Disease and Atypical Parkinsonian Disorders written by Biswajit Das and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Speech disorder is an early and prominent manifestation of neurological disorders. Therefore, the breakdown of speech disorders and detecting underlying pathophysiology have invaluable importance to clinical practice. Speech disorder is commonly attributed to aging onset, however, the pattern is mostly distinct for neurogenic voice. Parkinsonism is one of the neurological disorder that refers to idiopathic Parkinson's Disease (PD) and Atypical Parkinsonian Syndromes (APS), such as Progressive Supranuclear Palsy (PSP) and Multiple System Atrophy (MSA). Differential diagnosis of latter disease groups is remains an challenging task due to similar symptoms at the early stages, while early diagnostic certainty is essential for the patient because of the diverging prognosis. Indeed, despite recent efforts, no validated objective speech marker is currently available to guide the clinician for the differential diagnosis. This thesis thus aims to design and define the speech markers that would provide deep insight into speech disorders caused by neurological diseases, and followed by differential diagnosis.Analysis of speech disorder demands at least a speech database by which pattern of speech abnormalities can be assessed. Speech database consisting PD and MSA-P neurological diseases is not available in French language. Thus development of a speech database (Voice4PD-MSA) from PD and MSA-P groups was one of the target of this thesis. While developing Voice4PD-MSA database, we explored CzechData database comprises of speech samples in Czech language for differential diagnosis.The automatic algorithm always in demand to quantify perceptual and visual observation to capture particular speech disorders. Clinically interpretable speech components are considered to capture speech abnormalities in respiration, vowel production, articulator movements, and prosody by objective methods from sustained vowel, word-initial consonants, diadochokinetic (DDK) tasks, and continuous speech. Imprecise vowel comprises deficits in vocal folds opening and closing, involuntary movements of articulator, hypernasality, tremor, and changes in vowel space area are observed to be important for differential diagnosis of MSA-P and PD patients. In imprecise obstruents, devoicing in voiced obstruents and burst in fricatives (anti-spirantization) are identified as distinctive speech markers for MSA-P. In addition, speech indexes related to the subsystem of speech production and dysarthria yield encouraging differentiation and disease specificity in disease groups. Given small amount of data, two-dimensional speech features are designed such that one of the disease group predominates in one speech dimension and consequently discriminate disease groups with good classification score.Early differential diagnosis was another critical objective of the current investigation. The present study observed some encouraging indications about early differential diagnosis exploring the trend of speech markers w.r.t. clinical signs. Thus we aspire that the presented methodology in this thesis would serve as a potential diagnosis tool in clinical practice and further inspire to develop automatic methods to investigate speech disorders in parkinsonism.
Book Synopsis An Essay on the Shaking Palsy by : James Parkinson
Download or read book An Essay on the Shaking Palsy written by James Parkinson and published by . This book was released on 1817 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Dysarthrias by : Malcolm Ray McNeil
Download or read book The Dysarthrias written by Malcolm Ray McNeil and published by . This book was released on 1984 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neurologic Differential Diagnosis by : Alan B. Ettinger
Download or read book Neurologic Differential Diagnosis written by Alan B. Ettinger and published by Cambridge University Press. This book was released on 2014-04-17 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unique case-based guide to generating diagnostic possibilities based on the patients' symptoms. Invaluable for psychiatrists and neurologists.
Book Synopsis The Neurology of Olfaction by : Christopher H. Hawkes
Download or read book The Neurology of Olfaction written by Christopher H. Hawkes and published by Cambridge University Press. This book was released on 2009-02-12 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Written by two experts in the field, this book provides information useful to physicians for assessing and managing chemosensory disorders - with appropriate case-histories - and summarizes the current scientific knowledge of human olfaction. It will be of particular interest to neurologists, otolaryngologists, psychologists, psychiatrists, and neuroscientists."--BOOK JACKET.
Book Synopsis Diseases of the Brain, Head and Neck, Spine 2020–2023 by : Juerg Hodler
Download or read book Diseases of the Brain, Head and Neck, Spine 2020–2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
Book Synopsis Non-Motor Symptoms of Parkinson's Disease by : K. Ray Chaudhuri
Download or read book Non-Motor Symptoms of Parkinson's Disease written by K. Ray Chaudhuri and published by Oxford University Press, USA. This book was released on 2014 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus on the NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians. The NMS of PD have a significant impact on patient quality of life and mortality and include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require research into novel (non-dopaminergic) drug therapies for the future. Edited by members of the UK Parkinson's Disease Non-Motor Group (PD-NMG) and with contributions from international experts, this new edition summarizes the current understanding of NMS symptoms in Parkinson's disease and points the way towards future research.
Book Synopsis Movement Disorder Emergencies by : Steven J. Frucht
Download or read book Movement Disorder Emergencies written by Steven J. Frucht and published by Springer Science & Business Media. This book was released on 2008-02-10 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Movement Disorder Emergencies: Diagnosis and Treatment provides a fresh and unique approach to what is already a high-profile subspecialty area in clinical neurology. The disorders covered in this volume are standard fare in the field but emphasize the urgencies and emergencies that can occur. One of the very attractive features of the field of movement disorders is that diagnosis is often based on unique visible and sometimes audible phenomenological symptoms and signs. Therefore, in this era of highly sophisticated laboratory and radiological diagnostic tools, the diagnosis of many movement disorders is still largely made in the clinic where pattern recognition is key. Crucial to astute clinical diagnosis is broad clinical experience. In short, you have to have seen one to recognize one! Patients with movement disorders nearly always present as outpatients but, as aptly recognized by Drs. Frucht and Fahn, this may include acute manifestations leading to emergency presentations, often in an emergency room setting, where they are very likely to be unrecognized and therefore poorly managed. The authors define an “emergency” movement disorder as one in which failure to promptly diagnose and treat may result in significant morbidity or mortality. However, they also stress the importance of certain “can’t miss” diagnoses such as Wilson’s disease, dopa-responsive dystonia, and Whipple’s disease in which delayed diagnosis in less emergent situations can lead to slowly evolving and often irreversible neurological damage with tragic consequences.
Book Synopsis Applied Computing in Medicine and Health by : Dhiya Al-Jumeily
Download or read book Applied Computing in Medicine and Health written by Dhiya Al-Jumeily and published by Morgan Kaufmann. This book was released on 2015-08-21 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applied Computing in Medicine and Health is a comprehensive presentation of on-going investigations into current applied computing challenges and advances, with a focus on a particular class of applications, primarily artificial intelligence methods and techniques in medicine and health. Applied computing is the use of practical computer science knowledge to enable use of the latest technology and techniques in a variety of different fields ranging from business to scientific research. One of the most important and relevant areas in applied computing is the use of artificial intelligence (AI) in health and medicine. Artificial intelligence in health and medicine (AIHM) is assuming the challenge of creating and distributing tools that can support medical doctors and specialists in new endeavors. The material included covers a wide variety of interdisciplinary perspectives concerning the theory and practice of applied computing in medicine, human biology, and health care. Particular attention is given to AI-based clinical decision-making, medical knowledge engineering, knowledge-based systems in medical education and research, intelligent medical information systems, intelligent databases, intelligent devices and instruments, medical AI tools, reasoning and metareasoning in medicine, and methodological, philosophical, ethical, and intelligent medical data analysis. Discusses applications of artificial intelligence in medical data analysis and classifications Provides an overview of mobile health and telemedicine with specific examples and case studies Explains how behavioral intervention technologies use smart phones to support a patient centered approach Covers the design and implementation of medical decision support systems in clinical practice using an applied case study approach
Book Synopsis Handbook of Medical Image Computing and Computer Assisted Intervention by : S. Kevin Zhou
Download or read book Handbook of Medical Image Computing and Computer Assisted Intervention written by S. Kevin Zhou and published by Academic Press. This book was released on 2019-10-18 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Medical Image Computing and Computer Assisted Intervention presents important advanced methods and state-of-the art research in medical image computing and computer assisted intervention, providing a comprehensive reference on current technical approaches and solutions, while also offering proven algorithms for a variety of essential medical imaging applications. This book is written primarily for university researchers, graduate students and professional practitioners (assuming an elementary level of linear algebra, probability and statistics, and signal processing) working on medical image computing and computer assisted intervention. Presents the key research challenges in medical image computing and computer-assisted intervention Written by leading authorities of the Medical Image Computing and Computer Assisted Intervention (MICCAI) Society Contains state-of-the-art technical approaches to key challenges Demonstrates proven algorithms for a whole range of essential medical imaging applications Includes source codes for use in a plug-and-play manner Embraces future directions in the fields of medical image computing and computer-assisted intervention
Book Synopsis Rehabilitation in Movement Disorders by : Robert Iansek
Download or read book Rehabilitation in Movement Disorders written by Robert Iansek and published by Cambridge University Press. This book was released on 2013-05-23 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a broad overview of current rehabilitation approaches, emphasizing the need for interdisciplinary management and focussing on deliverable outcomes.
Book Synopsis Neuroimaging in Dementia by : Frederik Barkhof
Download or read book Neuroimaging in Dementia written by Frederik Barkhof and published by Springer Science & Business Media. This book was released on 2011-02-11 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.
Book Synopsis Atlas of Clinical Neurology by : Roger N. Rosenberg
Download or read book Atlas of Clinical Neurology written by Roger N. Rosenberg and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: '---~~~~-~~---------------. . . . . . . . . -. . . . . . . . . . . . . . . . . . . -. . . . . . . . . . . . . . . . . . . . . . . . . 41 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ••••••• he year 2001 marks the beginning of a new millenium, and (chromosome 1) result in dominantly inherited AD. A major risk T the second edition of the Atlas of Clinical Neurology high factor for AD is the presence of the E4 allele of apolipoprotein E lights and underscores the enormous strides being made in (chromosome 19). Additional detailed images related to the the biologic understanding of neurologic disease. Neurology is a dementias are included in the second edition of the Atlas. These highly visual specialty. The neurologic examination, magnetic reso clinical-molecular correlations are all very recent and attest to the nance imaging, electroencephalography, positron-emission tomo scientific vigor of current neuroscientific research. It is my view that graphic (PET) and functional magnetic resonance (fMRI) scan these new data will lead in the near future to effective new therapy ning, and light- and electron-microscopy are examples of visual for AD that will slow its rate of progress and reduce significantly images that define neurologic disease and normal brain functions. the incidence of this major, debilitating disease. Positron-emission This Atlas of Clinical Neurology has been designed to provide a pic tomographic and fMRI brain scanning have effectively defined torial comprehensive visual exposition and integration of all aspects regional brain areas for behaviors.
Book Synopsis Dementia with Lewy Bodies by : John O'Brien
Download or read book Dementia with Lewy Bodies written by John O'Brien and published by CRC Press. This book was released on 2005-11-29 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling a noticeable gap in the market for a new text solely focused on Dementia with Lewy Bodies, this book discusses cutting-edge topics covering the condition from diagnosis to management, as well as what is known about the neurobiological changes involved. With huge progress having been made over the last decade in terms of the disorder
Book Synopsis Dynamic Evaluation of Motor Speech Skill (Demss) Manual by : Edythe A. Strand
Download or read book Dynamic Evaluation of Motor Speech Skill (Demss) Manual written by Edythe A. Strand and published by Brookes Publishing Company. This book was released on 2018-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developed by one of the leading experts on childhood apraxia of speech (CAS) and an expert on test development, the DEMSS tool is an efficient way to assess children who have significant speech impairment, especially reduced phonemic and/or phonetic inventories, vowel or prosodic errors, poor speech intelligibility, and/or little to no verbal communication.
Book Synopsis Primary Progressive Aphasia and Other Frontotemporal Dementias by : Rene L. Utianski
Download or read book Primary Progressive Aphasia and Other Frontotemporal Dementias written by Rene L. Utianski and published by Plural Publishing. This book was released on 2019-09-16 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primary Progressive Aphasia and Other Frontotemporal Dementias: Diagnosis and Treatment of Associated Communication Disorders is the second volume in the “Medical Speech-Language Pathology” book series. It is intended to fill an unmet need to assist clinicians, students, and related healthcare professionals in the diagnosis and treatment of the title disorders. There is a growing population of individuals diagnosed with various forms of Frontotemporal Dementia (FTD) and Primary Progressive Aphasia (PPA), and this number is likely to increase as medical practitioners and speech-language pathologists (SLPs) become more expert at identifying these conditions. More clinicians will be seeing, and treating, patients with a diagnosis of FTD or PPA. Toward that end, the goal of this book is to expand this clinical knowledge base and support the development of skills in diagnosis, but also in clinical management. Within each chapter is a concise presentation of available evidence-based practice and research findings, with a focus on sharing information that is clinically applicable and digestible for non-researchers. Each chapter provides a comprehensive outline of testing that will assist in the diagnosis of the cognitive-communication disorders associated with FTD, PPAs, and primary progressive apraxia of speech (PPAOS). Disclaimer: Please note that ancillary content (such as documents, audio, and video, etc.) may not be included as published in the original print version of this book.
Book Synopsis Auditory Evoked Potentials by : Robert F. Burkard
Download or read book Auditory Evoked Potentials written by Robert F. Burkard and published by Lippincott Williams & Wilkins. This book was released on 2007 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts with extensive clinical and scientific experience, this comprehensive textbook presents the state of the art in auditory evoked potentials. Opening chapters explain the nature of electrical fields that generate surface recorded potentials, summarize the imaging modalities that complement evoked potential studies, and review acoustics and instrumentation. Major sections examine the anatomy and physiology of the auditory periphery, brainstem, and cortex and the principles and clinical applications of auditory, myogenic, visual, somatosensory, and vestibular evoked potentials. Chapters present hands-on laboratory exercises and clinical case studies. A full-color insert includes 3D images from multi-channel evoked potentials and functional imaging.
