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Asymmetric Synthesis And Application Of Alpha Amino Acids
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Book Synopsis Asymmetric Synthesis by : Gary M. Coppola
Download or read book Asymmetric Synthesis written by Gary M. Coppola and published by Wiley-Interscience. This book was released on 1987-01-19 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents in a logical, readable manner the synthetic utility of amino acids for the generation of chiral agents, intermediates, and final products by means of asymmetric synthesis. In the past 20 years asymmetric synthesis has forged to the forefront of organic chemistry. This book provides extensive schemes and reactions containing over 1900 structures to illustrate the varied assortment of chiral intermediates that can be generated from amino acids and their derivatives. Focuses on the alpha[l.c. Greek letter]-amino acids and second-generation intermediates that can be derived therefrom which are of general interest to organic chemists, in either the industrial or the academic environment. Special attention has been paid to the asymmetric synthesis of key pharmaceutical agents, agrochemicals, and a host of natural products including alkoloids, terpenoids, carbohydrates, and insect pheromones. Includes extensive and up-to-date references.
Book Synopsis Asymmetric Synthesis and Application of Alpha-Amino Acids by : Vadim A Soloshonok
Download or read book Asymmetric Synthesis and Application of Alpha-Amino Acids written by Vadim A Soloshonok and published by American Chemical Society. This book was released on 2009-07-09 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the most recent and comprehensive collection of reviews on methodological developments in the field of alpha-amino acids.
Book Synopsis Asymmetric Phase Transfer Catalysis by : Keiji Maruoka
Download or read book Asymmetric Phase Transfer Catalysis written by Keiji Maruoka and published by John Wiley & Sons. This book was released on 2008-09-08 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by the leading expert on the topic, this is the first book to present the latest developments in this exciting field. Alongside the theoretical aspects, the top contributors provide practical protocols to give readers additional important information otherwise unavailable. A must for every synthetic chemist in academia and industry.
Book Synopsis Enantioselective Synthesis of Beta-Amino Acids by : Eusebio Juaristi
Download or read book Enantioselective Synthesis of Beta-Amino Acids written by Eusebio Juaristi and published by John Wiley & Sons. This book was released on 2005-05-06 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all facets of the synthesis of ß-amino acids As evidenced by an exponential increase in the literature published on the subject, interest in ß-amino acids has grown over the past several years. With major pharmaceutical applications, these amino acids are now studied across multiple lines of research, including combinatorial chemistry, medicinal chemistry, molecular design, proteomics, and others. This Second Edition of Enantioselective Synthesis of ß-Amino Acids updates reviews included in the First Edition while also covering new developments since its publication. The book presents detailed discussions of the most important methods for the synthesis of ß-amino acids. In most cases, the lead chemist who originally developed a method provides an authoritative description of it. In addition, Enantioselective Synthesis of ß-Amino Acids, Second Edition: * Features introductory overviews on the structural types of relevant ß-amino acid targets and salient ß-amino acids present in natural products * Dedicates several chapters to advances in the synthesis of oligomers from ß-amino acids * Includes general and practical procedures for the preparation of ß-amino acids in each chapter * Discusses the most important methods that have been recently developed for the asymmetric synthesis of cyclic and open-chain ß-amino acids * Includes a report on the preparation of libraries of enantiopure ß-amino acids using combinatorial approaches The only book of its kind available today, Enantioselective Synthesis of ß-Amino Acids, Second Edition offers upper-level students and professionals an essential resource for pharmaceutical development, medicinal chemistry, and biochemistry.
Book Synopsis Asymmetric Catalysis on Industrial Scale by : Hans Ulrich Blaser
Download or read book Asymmetric Catalysis on Industrial Scale written by Hans Ulrich Blaser and published by John Wiley & Sons. This book was released on 2007-02-27 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by two of the experts in the field, the central aim is to show organic chemists working in process development that enantioselective catalysis is suitable for the large-scale production of enantioenriched intermediates. In so doing, it is equally a source of information and inspiration for academic research, and, with its contribution by Noble prizewinner W. S. Knowles, will also heighten the status of industrial catalyst specialists working in the exciting field of enantioselective catalysis. Some 25 contributions from top industrial researchers around the world present case studies on the development of the widest possible range of large-scale enantioselective processes, featuring stereoselective production processes of fine-chemicals, agrochemicals and pharmaceuticals. Clearly structured according to the nature of the task, this handbook adopts a problem-driven approach such that readers can easily find how colleagues have dealt with a similar situation.
Download or read book Amino Acid written by Toshiki Asao and published by BoD – Books on Demand. This book was released on 2017-06-28 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amino Acid - New Insights and Roles in Plant and Animal provides useful information on new aspects of amino acid structure, synthesis reactions, dietary application in animals, and metabolism in plants. Section 1 includes chapters that describe the therapeutic uses, antiallergic effects, new aspects in the D-amino acid structure, historical background of desmosines, and stereoselective synthesis of ?-aminophosphonic acids. Section 2 presents the role of amino acids in plants, which includes new insights and aspects of D-amino acids, metabolism and transport in soybean, changes during energy storage compound accumulation of microalgae, and determination of amino acids from natural compounds. Section 3 describes the chapters on methodologies and requirement of dietary amino acids for Japanese quails, laying hens, and finishing pigs. The final chapter identifies potential importance of glutathione S-transferase activity for generating resistance to triclabendazole in Fasciola hepatica.
Book Synopsis Fluorine-containing Amino Acids by : Valery P. Kukhar
Download or read book Fluorine-containing Amino Acids written by Valery P. Kukhar and published by John Wiley & Sons. This book was released on 1995-04-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, organo-fluorine chemistry has made a marked impact on the design and synthesis of a large variety of biologically active molecules, such as steroids, carbohydrates, amines, amino acids, peptides and other natural products. Naturally occurring amino acids play a pivotal role in living systems, and therefore synthetic fluorine-containing amino acids have been of significant interest to researchers working towards the understanding and modification of physiological processes. Fluorine-containing Amino Acids: is the first volume devoted to the synthesis and properties of fluorine-containing amino acids pays special attention to the preparation of enantiomerically pure acids (which are essential to the modern pharmaceutical industry) deals with a rapidly expanding field of research has been written by experienced researchers who are responsible for many developments in the field highlights the interdisciplinary nature of this topic Fluorine-containing Amino Acids is the only dedicated reference in this subject and will be essential for researchers in synthetic organic, peptide, natural product, and medicinal chemistry and biochemistry.
Book Synopsis Chiral Amine Synthesis by : Thomas C. Nugent
Download or read book Chiral Amine Synthesis written by Thomas C. Nugent and published by John Wiley & Sons. This book was released on 2010-01-14 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first comprehensive presentation of this hot and important topic compiles the most up-to-date methods for chiral amine synthesis. The international list of authors reads like a "Who's Who" of the subject, providing a large array of highly practical information concentrated into the useful and essential methods. Following an introductory chapter devoted to helping readers quickly determine which strategies to choose for their investigation, this handbook and ready reference focuses on the examination of methods that are reliable and simultaneously efficient for the synthesis of structurally diverse aliphatic and aromatic chiral amines. Modern methods and applications found in (pharmaceutical) industry are also covered.
Book Synopsis Catalytic Asymmetric Synthesis by : Takahiko Akiyama
Download or read book Catalytic Asymmetric Synthesis written by Takahiko Akiyama and published by John Wiley & Sons. This book was released on 2022-05-27 with total page 798 pages. Available in PDF, EPUB and Kindle. Book excerpt: Catalytic Asymmetric Synthesis Seminal text presenting detailed accounts of the most important catalytic asymmetric reactions known today This book covers the preparation of enantiomerically pure or enriched chemical compounds by use of chiral catalyst molecules. While reviewing the most important catalytic methods for asymmetric organic synthesis, this book highlights the most important and recent developments in catalytic asymmetric synthesis. Edited by two well-qualified experts, sample topics covered in the work include: Metal catalysis, organocatalysis, photoredox catalysis, enzyme catalysis C–H bond functionalization reactions Carbon–carbon bond formation reactions, carbon–halogen bond formation reactions, hydrogenations, polymerizations, flow reactions Axially chiral compounds Retaining the best of its predecessors but now thoroughly up to date with the important and recent developments in catalytic asymmetric synthesis, the 4th edition of Catalytic Asymmetric Synthesis serves as an excellent desktop reference and text for researchers and students, from upper-level undergraduates all the way to experienced professionals in industry or academia.
Book Synopsis Asymmetric Synthesis in Organophosphorus Chemistry by : Oleg I. Kolodiazhnyi
Download or read book Asymmetric Synthesis in Organophosphorus Chemistry written by Oleg I. Kolodiazhnyi and published by John Wiley & Sons. This book was released on 2016-12-19 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by one of the leading experts in the field, this is the only comprehensive overview of chiral organophosphorus compounds, from asymmetric synthesis to catalysis and pharmacological applications. As such, this unique reference covers the chemical background as well as spectroscopical analysis of phosphorus compounds, and thoroughly describes all the various synthetic strategies for these substances. Metal-, organo- and biocatalyzed reactions for the introduction of phosphorus are explained as are asymmetric oxidation and reduction methods for the preparation of all possible oxidation states of phosphorus. The text also includes industrial applications for these compounds. Of particular interest to chemists working in the field of asymmetric synthesis, as well as to the pharmaceutical industry due to the increasing number of phosphorous-containing drugs.
Book Synopsis Salts of Amino Acids by : Michel Fleck
Download or read book Salts of Amino Acids written by Michel Fleck and published by Springer. This book was released on 2014-07-08 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decades, amino acids have been found to be of importance in many fields of science. Apart from their biological function, this family of organic compounds has been employed in the synthesis of a vast variety of salts, with impact on areas such as materials science, pharmaceutical or physical research. This covers a wide range, from the discovery of important ferroelectrics or non-linear optical materials to nutrients, flavor enhancers or drugs. This book describes amino acids and their salts with cations, anions and inorganic compounds from a chemical, physical and crystallographical point of view. Additional data on structural properties, crystal growth and the relation of structure and physical properties of amino acid salts is discussed.
Book Synopsis Organic Chemistry from Retrosynthesis to Asymmetric Synthesis by : Vitomir Šunjić
Download or read book Organic Chemistry from Retrosynthesis to Asymmetric Synthesis written by Vitomir Šunjić and published by Springer. This book was released on 2016-04-30 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book connects a retrosynthetic or disconnection approach with synthetic methods in the preparation of target molecules from simple, achiral ones to complex, chiral structures in the optically pure form. Retrosynthetic considerations and asymmetric syntheses are presented as closely related topics, often in the same chapter, underlining the importance of retrosynthetic consideration of target molecules neglecting stereochemistry and equipping readers to overcome the difficulties they may encounter in the planning and experimental implementation of asymmetric syntheses. This approach prepares students in advanced organic chemistry courses, and in particular young scientists working at academic and industrial laboratories, for independently solving synthetic problems and creating proposals for the synthesis of complex structures.
Book Synopsis Stereochemistry of Radical Reactions by : Dennis P. Curran
Download or read book Stereochemistry of Radical Reactions written by Dennis P. Curran and published by John Wiley & Sons. This book was released on 2008-09-26 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: As little as a decade ago, radicals were regarded as interesting reactive intermediates with little synthetic use. However, recent results show that radicals have an enormous potential for applications in stereoselective reactions - it's all a matter of knowing what method to use and how to apply it. Three world experts in the field have combined their expertise and present the concepts to understand and even to predict the course of stereoselective radical reactions. In addition, guidelines are established which will enable the readers to plan and carry out their own stereoselective syntheses with radicals. A comprehensive list of references provides an easy access to the primary literature. The Stereochemistry of Radical Reactions is a highly topical introduction to this burgeoning field of research. Both advanced students and researchers active in the field will welcome this book as a source of concepts and ideas.
Book Synopsis Chemistry and Biochemistry of the Amino Acids by : Graham Barrett
Download or read book Chemistry and Biochemistry of the Amino Acids written by Graham Barrett and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amino acids are featured in course syllabuses and in project and research work over a wide spectrum of subject areas in chemistry and biology. Chemists and biochemists using amino acids have many common needs when they turn to the literature for comprehensive information. Among these common interests, analytical studies, in particular, have undergone rapid development in recent years. All other chemical and biochemical aspects of amino acids - synthesis, properties and reactions, preparation of derivatives for use in peptide synthesis, racemization and other fundamental mechanistic knowledge - have been the subject of vigorous progress. This book offers a thorough treatment of all these developing areas, and is structured in the belief that biochemists, physiologists and others will profit from access to information on topics such as the physical chemistry of amino acid solutions, as well as from thorough coverage of amino acid metabolism, biosynthesis and enzyme inhibition; and that chemists will find relevant material in biological areas as well as in the analysis, synthesis and reactions of amino acids.
Book Synopsis Peptide Analysis Protocols by : Ben M. Dunn
Download or read book Peptide Analysis Protocols written by Ben M. Dunn and published by Humana. This book was released on 2013-12-06 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the technology base for the preparation of increasingly c- plex peptides has improved, the methods for their purification and ana- sis have also been improved and supplemented. Peptide science routinely utilizes tools and techniques that are common to organic chemistry, p- tein chemistry, biophysical chemistry, enzymology, pharmacology, and molecular biology. A fundamental understanding of each of these areas is essential for interpreting all of the data that a peptide scientist may see. The purpose of Peptide Analysis Protocols is to provide the novice with sufficient practical information necessary to begin developing useful analysis and separation skills. Understanding and developing these skills will ultimately yield a scientist with broadened knowledge and good problem-solving abilities. Although numerous books that address d- ferent specialties, such as HPLC, FAB-MS, CE, and NMR, have been written, until now no single volume has reviewed all of these techniques with a focus on "getting started" in separation and analysis of peptides. This volume will also provide those who already possess practical knowledge of the more advanced aspects of peptide science with detailed applications for each of these protocols. Because the chapters have been written by researchers active in each of the fields that they discuss, a great deal of information on and insight into solution of real problems that they have encountered is presented. Examplary results are clearly demonstrated and discussed. For more advanced investi- tions, supplementary experiments are often suggested.
Book Synopsis Principles and Applications of Asymmetric Synthesis by : Guo-Qiang Lin
Download or read book Principles and Applications of Asymmetric Synthesis written by Guo-Qiang Lin and published by John Wiley & Sons. This book was released on 2003-05-29 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asymmetric synthesis remains a challenge to practicing scientistsas the need for enantiomerically pure or enriched compoundscontinues to increase. Over the last decade, a large amount ofliterature has been published in this field. Principles andApplications of Asymmetric Synthesis consolidates and evaluates themost useful methodologies into a one-volume resource for theconvenience of practicing scientists and students. Authored by internationally renowned scientists in the field, thisreliable reference covers more than 450 reactions and includesimportant stoichiometric as well as catalytic asymmetric reactions.The first chapter reviews the basic principles, commonnomenclature, and analytical methods, and the remainder of the bookis organized according to reaction type. The text examines suchtopics as: Carbon-carbon bond formations involving carbonyls, enamines,imines, and enolates Asymmetric C-O bond formations including epoxidation,dihydroxylation, and aminohydroxylation Asymmetric synthesis using the Diels-Alder reaction and othercyclizations Applications to the total synthesis of natural products Use of enzymes in asymmetric synthesis Practicing chemists in the pharmaceutical, fine chemical, andagricultural professions as well as graduate students will findthat Principles and Applications of Asymmetric Synthesis affordscomprehensive and current coverage.
Book Synopsis New Frontiers in Asymmetric Catalysis by : Koichi Mikami
Download or read book New Frontiers in Asymmetric Catalysis written by Koichi Mikami and published by John Wiley & Sons. This book was released on 2007-02-16 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compilation of recent advances and applications in asymmetric catalysis The field of asymmetric catalysis has grown rapidly and plays a key role in drug discovery and pharmaceuticals. New Frontiers in Asymmetric Catalysis gives readers a fundamental understanding of the concepts and applications of asymmetric catalysis reactions and discusses the latest developments and findings. With contributions from preeminent scientists in their respective fields, it covers: * "Rational" ligand design, which is critically dependent on the reaction type (reduction, oxidation, and C-C bond formation) * Recent findings on activation of C-H bonds, C-C bonds, and small molecules (C=O, HCN, RN=C, and CO2) and the latest developments on C-C bond reorganization, such as metathesis * Advances in "chirally economical" non-linear phenomena, racemic catalysis, and autocatalysis * Some of the recent discoveries that have led to a renaissance in the field of organocatalysis, including the development of chiral Brönstead acids and Lewis acidic metals bearing the conjugate base of the Brönstead acids as the ligands and the chiral bi-functional acid/base catalysts The book ends with a thought-provoking perspective on the future of asymmetric catalysis that addresses both the challenges and the unlimited potential in this burgeoning field. This is an authoritative, up-to-date reference for organic chemists in academia, government, and industries, including pharmaceuticals, biotech, fine chemicals, polymers, and agriculture. It is also an excellent textbook for graduate students studying advanced organic chemistry or chemical synthesis.
