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Author : J.P. Seiler
Publisher :
ISBN 13 :
Total Pages : 417 pages
Book Rating : 4.:/5 (112 download)
Download or read book Applied toxicology: approaches through basic science written by J.P. Seiler and published by . This book was released on 1997 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jürg P. Seiler
Publisher : Springer Science & Business Media
ISBN 13 : 3642606822
Total Pages : 396 pages
Book Rating : 4.6/5 (426 download)
Download or read book Applied Toxicology: Approaches Through Basic Science written by Jürg P. Seiler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultraviolet radiation, a component of sunlight, has been recognized by photobiologists, dermatologists, and oculists as a potential hazard for human health because of its genotoxic, carcinogenic and immunotoxic properties. Its effects on human health include the induction of skin cancers, ocular damage and impairment of immunity to certain infections. A few decennia ago it was demonstrated that UV photons can affect the activity of the immune system through interactions with the skin. This means that UV not only changes normal cells into cancer cells but also permits the outgrowth of the UV -transformed cells by depressing the immune system. An intriguing question is what interactions between UV radiation and the skin initiates alterations in immune function in the exposed skin and systemically, i. e. in other places than the exposed skin. During the last 20 years many studies have been performed in order to investigate the immunosuppressive activities of UVB in laboratory animals and in human volunteers. In particular effects of UVB radiation on resistance to tumours and skin associated infections have been examined. In addition, effects of UVB radiation on immune parameters such as contact hypersensitivity and delayed-type hypersensitivity (both type IV hypersensitivity reactions), mixed lymphocyte reactions, mixed skin lymphocyte reactions, antigen presentation and numbers and function of Langerhans cells have been studied intensively. The antigenicity of murine tumours which are caused by UVB radiation was one of the first items to be investigated (Kripke, 1974).
Author : European Society of Toxicology. Congress
Publisher :
ISBN 13 :
Total Pages : 417 pages
Book Rating : 4.:/5 (489 download)
Download or read book Applied Toxicology: Approaches Through Basic Science written by European Society of Toxicology. Congress and published by . This book was released on 1997 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Bryan Ballantyne
Publisher :
ISBN 13 : 9781561592425
Total Pages : 2199 pages
Book Rating : 4.5/5 (924 download)
Download or read book General and Applied Toxicology written by Bryan Ballantyne and published by . This book was released on 1999 with total page 2199 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : A. Wallace Hayes
Publisher : CRC Press
ISBN 13 : 1000875776
Total Pages : 2143 pages
Book Rating : 4.0/5 (8 download)
Download or read book Hayes' Principles and Methods of Toxicology written by A. Wallace Hayes and published by CRC Press. This book was released on 2023-07-03 with total page 2143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters have been updated and over 60 new authors have been added to reflect the dynamic nature of toxicological sciences New topics in this edition include Safety Assessment of Cosmetics and Personal Care Products, The Importance of the Dose/Rate Response, Novel Approaches and Alternative Models, Epigenetic Toxicology, and an Expanded Glossary. The volume is divided into 4 major sections, addressing fundamental principles of toxicology (Section I. "Principles of Toxicology"), major classes of established chemical hazards (Section II. "Agents"), current methods used for the assessment of various endpoints indicative of chemical toxicity (Section III. "Methods"), as well as toxicology of specific target systems and organs (Section IV. "Organ- and System-Specific Toxicology"). This volume will be a valuable tool for the audience that wishes to broaden their understanding of hazards and mechanisms of toxicity and to stay on top of the emerging methods and concepts of the rapidly advancing field of toxicology and risk assessment.
Author : Bryan Ballantyne
Publisher : Wiley-Blackwell
ISBN 13 :
Total Pages : 792 pages
Book Rating : 4.F/5 ( download)
Download or read book General and Applied Toxicology, 6 Volume Set written by Bryan Ballantyne and published by Wiley-Blackwell. This book was released on 2009-12-02 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encompassing 150 articles written by leading scientists in the field, the third edition of General and Applied Toxicology provides a comprehensive and in-depth review of the basic science of toxicology, its specializations, and the application of toxicological knowledge. This new edition reflects developments within the field that have taken place since the second edition was published in 1999. These include: New information developed in the areas of both the fundamental and applied aspects of toxicology Considerable increase in the development of fundamental information and its applications, refinement of technical methods, advances in mechanistic toxicology, and greater interest in areas of toxicology previously regarded as of limited scope Changing approaches to methodological, interpretative, regulatory, and ethical aspects of basic and applied toxicology General and Applied Toxicology, 3rd Edition is the first port of call for academic researchers, industrial researchers, regulatory professionals, and advanced students looking for timely and authoritative information in the field. Due to the increase in public and media interest in exposure to toxic substances, this provides an indispensable general reference source for general physicians, lawyers, law enforcement agencies, information resource facilities, and members of the general public. New online resource available now! In 2011, the content from the third edition of General and Applied Toxicology merged with the two-volume Handbook of Systems Toxicology. The result? General, Applied and Systems Toxicology - a new online resource combining traditional toxicology with the latest developments to present the ultimate reference in toxicology! For full details visit wileyonlinelibrary.com/ref/gast
Author : Bryan Ballantyne
Publisher : Elsevier
ISBN 13 : 1483193535
Total Pages : 406 pages
Book Rating : 4.4/5 (831 download)
Download or read book Perspectives in Basic and Applied Toxicology written by Bryan Ballantyne and published by Elsevier. This book was released on 2016-10-27 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perspectives in Basic and Applied Toxicology features a collection of essays on various aspects of toxicology. It aims to relate fundamental knowledge of toxicology to its application in assessing relevance of that information to the causation of adverse health effects, predicting hazardous situations, defining protective and precautionary measures, and the recognition and management of intoxication in humans. Another objective of this volume is to encourage those with responsibility for the training of toxicologists to instill a greater concern about ethical and moral issues as fundamental to the practice of toxicology as a profession with wide-ranging social implications. This book is organized into 14 chapters. The coverage of these chapters include assessment of chemical hazards in the workplace, the relation between animal studies and epidemiology in the context of industrial toxicology, carcinogenicity testing in animals, and biochemical evaluation of neurotoxicity. This book will be of interest to undergraduate and graduate toxicologists, pharmacologists, physicians, industrial hygienists, and other health professionals.
Author : Philip Wexler
Publisher : Academic Press
ISBN 13 : 0127447709
Total Pages : 953 pages
Book Rating : 4.1/5 (274 download)
Download or read book Information Resources in Toxicology written by Philip Wexler and published by Academic Press. This book was released on 2000 with total page 953 pages. Available in PDF, EPUB and Kindle. Book excerpt: History: -- K.D. Watson, P. Wexler, and J. Everitt. -- Highlights in the History of Toxicology. -- Selected References in the History of Toxicology. -- A Historical Perspective of Toxicology Information Systems. -- Books and Special Documents: -- G.L. Kennedy, Jr., P. Wexler, N.S. Selzer, and L.A. Malley. -- General Texts. -- Analytical Toxicology. -- Animals in Research. -- Biomonitoring/Biomarkers. -- Biotechnology. -- Biotoxins. -- Cancer. -- Chemical Compendia. -- Chemical--Cosmetics and Other Consumer. -- Products. -- Chemical--Drugs. -- Chemical--Dust and Fibers. -- Chemical--Metals. -- Chemicals--Pesticides -- Chemicals--Solvents. -- Chemical--Selected Chemicals. -- Clinical Toxicology. -- Developmental and Reproductive Toxicology. -- Environmental Toxicology--General. -- Environmental Toxicology-- Aquatic. -- Environmental Toxicology--Atmospheric. -- Environmental Toxicology--Hazardous Waste. -- Environmental Toxicology--Terrestrial. -- Environmental Toxicology--Wildlife. -- Ep ...
Author : Brad Reisfeld
Publisher : Humana Press
ISBN 13 : 9781493963263
Total Pages : 662 pages
Book Rating : 4.9/5 (632 download)
Download or read book Computational Toxicology written by Brad Reisfeld and published by Humana Press. This book was released on 2016-05-01 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: This resource features essential background, context, examples, useful tips, and an overview of current developments in the field. It includes cutting-edge methods and protocols as well as implementation advice from the experts.
Author : Rudy J Richardson
Publisher : Royal Society of Chemistry
ISBN 13 : 1782623329
Total Pages : 348 pages
Book Rating : 4.7/5 (826 download)
Download or read book Computational Systems Pharmacology and Toxicology written by Rudy J Richardson and published by Royal Society of Chemistry. This book was released on 2017-03-03 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. Computational approaches have the potential to improve toxicological experimental design, enable more rapid drug efficacy and safety testing and also reduce the number of animals used in experimentation. Rapid advances in availability of computing technology hold tremendous promise for advancing applied and basic science and increasing the efficiency of risk assessment. This book provides an understanding of the basic principles of computational toxicology and the current methods of predictive toxicology using chemical structures, toxicity-related databases, in silico chemical-protein docking, and biological pathway tools. The book begins with an introduction to systems pharmacology and toxicology and computational tools followed by a section exploring modelling adverse outcomes and events. The second part of the book covers the discovery of protein targets and the characterisation of toxicant-protein interactions. Final chapters include case studies and additionally discuss interactions between phytochemicals and Western therapeutics. This book will be useful for scientists involved in environmental research and risk assessment. It will be a valuable resource for postgraduate students and researchers wishing to learn about key methods used in studying biological targets both from a toxicity and pharmacological activity standpoint.
Author : DR. MUNEESH KUMAR
Publisher : DARSHAN PUBLISHERS
ISBN 13 : 9386739089
Total Pages : pages
Book Rating : 4.3/5 (867 download)
Download or read book A TEXTBOOK OF APPLIED TOXICOLOGY written by DR. MUNEESH KUMAR and published by DARSHAN PUBLISHERS. This book was released on 2021-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an introduction to applied toxicology and is designed primarily for Post graduate students and Research scholars. Now days the whole world is facing a pandemic of the most dreaded human disease caused by toxicants. Therefore study of applied toxicology serves society in many ways, not only to protect humans and the environment from the deleterious effects of toxicants but also to facilitate the development of more selective toxicants such as anticancer and other clinical drugs and pesticides. In chapters covering rapidly expanding matter, the usually required material has been presented in a fairly concise form, and then details on special aspects have been given in the form of addenda. It is hoped that this approach will meet the needs of Post graduate students, Research scholars and provide sources for more advanced study. Efforts have been made to include the latest available information in some chapters to make the book upto-date. The constructive suggestion from the conscious readers is always cordially invited for further improvement of the book. The study of toxic action from the use of biochemical and molecular techniques can be expected. No doubt new techniques will be developed, answers will be found to many questions that did not yield to earlier techniques and new questions will be raised. The challenge, as always, will be to integrate the results from these studies and reach new levels of sophistication into useful and productive approaches to reduce chemical effects on human health and the environment.
Author : Louis J. Casarett
Publisher : McGraw-Hill Companies
ISBN 13 :
Total Pages : 1138 pages
Book Rating : 4.3/5 (91 download)
Download or read book Casarett and Doull's Toxicology written by Louis J. Casarett and published by McGraw-Hill Companies. This book was released on 1996 with total page 1138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated & revised, this fifth edition delineates the basic concepts & fundamental principles needed to grasp current issues in modern toxicology. As in previous editions, the book successfully balances its encyclopedic coverage with a basic, fundamental, mechanistic approach to toxicology. The text is organized & presented in a logical progression of general principles to specific topics such as organ system toxicology, specific agent toxicology, & environmental toxicology.
Author : Bruce A. Fowler
Publisher : Academic Press
ISBN 13 : 012396508X
Total Pages : 275 pages
Book Rating : 4.1/5 (239 download)
Download or read book Computational Toxicology written by Bruce A. Fowler and published by Academic Press. This book was released on 2013-06-04 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Toxicology: Methods and Applications for Risk Assessment is an essential reference on the translation of computational toxicology data into information that can be used for more informed risk assessment decision-making. This book is authored by leading international investigators who have real-world experience in relating computational toxicology methods to risk assessment. Key topics of interest include QSAR modeling, chemical mixtures, applications to metabolomic and metabonomic data sets, toxicogenomic analyses, applications to REACH informational strategies and much more. The examples provided in this book are based on cutting-edge technologies and set out to stimulate the further development of this promising field to offer rapid, better and more cost-effective answers to major public health concerns. Authored by leading international researchers engaged in cutting-edge applications of computational methods for translating complex toxicological data sets into useful risk assessment information Incorporates real-world examples of how computational toxicological methods have been applied to advance the science of risk assessment Provides the framework necessary for new technologies and fosters common vocabularies and principles upon which the effects of new chemical entities should be compared
Author : K. Esser
Publisher : Springer Science & Business Media
ISBN 13 : 3642572030
Total Pages : 380 pages
Book Rating : 4.6/5 (425 download)
Download or read book Progress in Botany written by K. Esser and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: With one volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of the plant sciences. The present volume includes reviews on genetics, cell biology, and vegetation science.
Author : Bryan Ballantyne
Publisher : Grove's Dictionaries
ISBN 13 :
Total Pages : 938 pages
Book Rating : 4.3/5 (91 download)
Download or read book General & Applied Toxicology written by Bryan Ballantyne and published by Grove's Dictionaries. This book was released on 1993 with total page 938 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume work gives comprehensive coverage of the scientific basis of toxicology and its applications. Both general and specialist needs are considered, with particular reference to basic principles, definitions, laboratory aspects, interpretations of data and practical applications of toxicology. Thus, there are sections devoted to basic concepts, techniques, toxicity by specific routes of exposure and by organ system, special aspects of toxicology, and the increasingly dominant area of regulatory toxicology. The book is designed so that it can be used as a sole or main text for course work for examinations such as those of the Royal College of Pathologists, Institute of Biology and American Board of Toxicology.
Author : A. Wallace Hayes
Publisher : CRC Press
ISBN 13 : 1842145363
Total Pages : 2186 pages
Book Rating : 4.8/5 (421 download)
Download or read book Hayes' Principles and Methods of Toxicology, Sixth Edition written by A. Wallace Hayes and published by CRC Press. This book was released on 2014-10-10 with total page 2186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.
Author : Franz-Xaver Reichl
Publisher : Springer
ISBN 13 : 9783642353734
Total Pages : 0 pages
Book Rating : 4.3/5 (537 download)
Download or read book Regulatory Toxicology written by Franz-Xaver Reichl and published by Springer. This book was released on 2014-03-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will be written by experts for professionals, scientists and all those involved in toxicological data generation and decision-making. It is the updated and expanded version of a monograph published in German in 2004. Chemical safety is regulated on various levels including production, storage, transport, handling, disposal or labelling. This book deals comprehensively with the safety-ensuring methods and concepts employed by regulatory agencies, industry and academics. Toxicologists use experimental and scientific approaches for data collection, e.g. about chemical hazards, physicochemical features or toxicokinetics. The respective experimental methods are described in the book. Toxicologists also deal with much insecurity in the exposure and effect scenarios during risk assessment. To overcome these, they have different extrapolation methods and estimation procedures at their disposal. The book describes these methods in an accessible manner. Differing concepts from one regulation area to another are also covered. Reasons and consequences become evident when reading the book. Altogether, the book Regulatory Toxicology will serve as an excellent reference.
