Applications Of Statistical And Machine Learning Methods In Bioinformatics

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Applications of Statistical and Machine Learning Methods in Bioinformatics

Author : Jaroslaw Meller
Publisher : Peter Lang Gmbh, Internationaler Verlag Der Wissenschaften
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Applications of Statistical and Machine Learning Methods in Bioinformatics by : Jaroslaw Meller

Download or read book Applications of Statistical and Machine Learning Methods in Bioinformatics written by Jaroslaw Meller and published by Peter Lang Gmbh, Internationaler Verlag Der Wissenschaften. This book was released on 2007 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical and machine learning approaches play an increasingly important role in biomedical research. In the absence of fundamental (first principle-based) models, or because of the computational complexity of such models, statistical and machine learning approaches are being used to identify interesting structures in the data (e.g. patterns in gene expression profiles), correlate these patterns and other «input» attributes with (e.g. medically) relevant outcomes, and to develop predictors that can generalize from known data and make predictions for new data instances. Examples of important applications include structural bioinformatics, in which one of the goals is to predict elements of protein structure from amino acid sequence, or microarray gene expression profiling, in which the goal is to discover interesting patterns in gene expression data and correlate them with clinically relevant phenotypes. This volume includes papers submitted to the BIT 2005 workshop on the Applications of Machine and Statistical Learning Methods in Bioinformatics that took place in September 2005 in Torun, Poland.

Applications of Statistical and Machine Learning Methods in Bioinformatics

Author : Jaroslaw Meller
Publisher : Peter Lang Pub Incorporated
ISBN 13 : 9780820487939
Total Pages : 128 pages
Book Rating : 4.4/5 (879 download)

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Book Synopsis Applications of Statistical and Machine Learning Methods in Bioinformatics by : Jaroslaw Meller

Download or read book Applications of Statistical and Machine Learning Methods in Bioinformatics written by Jaroslaw Meller and published by Peter Lang Pub Incorporated. This book was released on 2007-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical and machine learning approaches play an increasingly important role in biomedical research. In the absence of fundamental (first principle-based) models, or because of the computational complexity of such models, statistical and machine learning approaches are being used to identify interesting structures in the data (e.g. patterns in gene expression profiles), correlate these patterns and other -input attributes with (e.g. medically) relevant outcomes, and to develop predictors that can generalize from known data and make predictions for new data instances. Examples of important applications include structural bioinformatics, in which one of the goals is to predict elements of protein structure from amino acid sequence, or microarray gene expression profiling, in which the goal is to discover interesting patterns in gene expression data and correlate them with clinically relevant phenotypes. This volume includes papers submitted to the BIT 2005 workshop on the Applications of Machine and Statistical Learning Methods in Bioinformatics that took place in September 2005 in Torun, Poland."

Statistical Modelling and Machine Learning Principles for Bioinformatics Techniques, Tools, and Applications

Author : K. G. Srinivasa
Publisher : Springer Nature
ISBN 13 : 9811524459
Total Pages : 318 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Statistical Modelling and Machine Learning Principles for Bioinformatics Techniques, Tools, and Applications by : K. G. Srinivasa

Download or read book Statistical Modelling and Machine Learning Principles for Bioinformatics Techniques, Tools, and Applications written by K. G. Srinivasa and published by Springer Nature. This book was released on 2020-01-30 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses topics related to bioinformatics, statistics, and machine learning, presenting the latest research in various areas of bioinformatics. It also highlights the role of computing and machine learning in knowledge extraction from biological data, and how this knowledge can be applied in fields such as drug design, health supplements, gene therapy, proteomics and agriculture.

Statistical Modelling and Machine Learning Principles for Bioinformatics Techniques, Tools, and Applications

Author : K. G. Srinivasa
Publisher :
ISBN 13 : 9789811524462
Total Pages : 318 pages
Book Rating : 4.5/5 (244 download)

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Book Synopsis Statistical Modelling and Machine Learning Principles for Bioinformatics Techniques, Tools, and Applications by : K. G. Srinivasa

Download or read book Statistical Modelling and Machine Learning Principles for Bioinformatics Techniques, Tools, and Applications written by K. G. Srinivasa and published by . This book was released on 2020 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses topics related to bioinformatics, statistics, and machine learning, presenting the latest research in various areas of bioinformatics. It also highlights the role of computing and machine learning in knowledge extraction from biological data, and how this knowledge can be applied in fields such as drug design, health supplements, gene therapy, proteomics and agriculture.

Bioinformatics Applications Based On Machine Learning

Author : Pablo Chamoso
Publisher : MDPI
ISBN 13 : 3036507604
Total Pages : 206 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Bioinformatics Applications Based On Machine Learning by : Pablo Chamoso

Download or read book Bioinformatics Applications Based On Machine Learning written by Pablo Chamoso and published by MDPI. This book was released on 2021-09-01 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: The great advances in information technology (IT) have implications for many sectors, such as bioinformatics, and has considerably increased their possibilities. This book presents a collection of 11 original research papers, all of them related to the application of IT-related techniques within the bioinformatics sector: from new applications created from the adaptation and application of existing techniques to the creation of new methodologies to solve existing problems.

Application of Novel Statistical and Machine-learning Methods to High-dimensional Clinical Cancer and (Multi-)Omics data

Author : Chao Xu
Publisher : Frontiers Media SA
ISBN 13 : 2889714365
Total Pages : 136 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Application of Novel Statistical and Machine-learning Methods to High-dimensional Clinical Cancer and (Multi-)Omics data by : Chao Xu

Download or read book Application of Novel Statistical and Machine-learning Methods to High-dimensional Clinical Cancer and (Multi-)Omics data written by Chao Xu and published by Frontiers Media SA. This book was released on 2022-02-02 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Statistical Data Modeling and Machine Learning with Applications

Author : Snezhana Gocheva-Ilieva
Publisher : Mdpi AG
ISBN 13 : 9783036526928
Total Pages : 184 pages
Book Rating : 4.5/5 (269 download)

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Book Synopsis Statistical Data Modeling and Machine Learning with Applications by : Snezhana Gocheva-Ilieva

Download or read book Statistical Data Modeling and Machine Learning with Applications written by Snezhana Gocheva-Ilieva and published by Mdpi AG. This book was released on 2021-12-21 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: The modeling and processing of empirical data is one of the main subjects and goals of statistics. Nowadays, with the development of computer science, the extraction of useful and often hidden information and patterns from data sets of different volumes and complex data sets in warehouses has been added to these goals. New and powerful statistical techniques with machine learning (ML) and data mining paradigms have been developed. To one degree or another, all of these techniques and algorithms originate from a rigorous mathematical basis, including probability theory and mathematical statistics, operational research, mathematical analysis, numerical methods, etc. Popular ML methods, such as artificial neural networks (ANN), support vector machines (SVM), decision trees, random forest (RF), among others, have generated models that can be considered as straightforward applications of optimization theory and statistical estimation. The wide arsenal of classical statistical approaches combined with powerful ML techniques allows many challenging and practical problems to be solved. This Special Issue belongs to the section "Mathematics and Computer Science". Its aim is to establish a brief collection of carefully selected papers presenting new and original methods, data analyses, case studies, comparative studies, and other research on the topic of statistical data modeling and ML as well as their applications. Particular attention is given, but is not limited, to theories and applications in diverse areas such as computer science, medicine, engineering, banking, education, sociology, economics, among others. The resulting palette of methods, algorithms, and applications for statistical modeling and ML presented in this Special Issue is expected to contribute to the further development of research in this area. We also believe that the new knowledge acquired here as well as the applied results are attractive and useful for young scientists, doctoral students, and researchers from various scientific specialties.

Multivariate Statistical Machine Learning Methods for Genomic Prediction

Author : Osval Antonio Montesinos López
Publisher : Springer Nature
ISBN 13 : 3030890104
Total Pages : 707 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Multivariate Statistical Machine Learning Methods for Genomic Prediction by : Osval Antonio Montesinos López

Download or read book Multivariate Statistical Machine Learning Methods for Genomic Prediction written by Osval Antonio Montesinos López and published by Springer Nature. This book was released on 2022-02-14 with total page 707 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license This open access book brings together the latest genome base prediction models currently being used by statisticians, breeders and data scientists. It provides an accessible way to understand the theory behind each statistical learning tool, the required pre-processing, the basics of model building, how to train statistical learning methods, the basic R scripts needed to implement each statistical learning tool, and the output of each tool. To do so, for each tool the book provides background theory, some elements of the R statistical software for its implementation, the conceptual underpinnings, and at least two illustrative examples with data from real-world genomic selection experiments. Lastly, worked-out examples help readers check their own comprehension.The book will greatly appeal to readers in plant (and animal) breeding, geneticists and statisticians, as it provides in a very accessible way the necessary theory, the appropriate R code, and illustrative examples for a complete understanding of each statistical learning tool. In addition, it weighs the advantages and disadvantages of each tool.

Data Analytics in Bioinformatics

Author : Rabinarayan Satpathy
Publisher : John Wiley & Sons
ISBN 13 : 1119785618
Total Pages : 544 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Data Analytics in Bioinformatics by : Rabinarayan Satpathy

Download or read book Data Analytics in Bioinformatics written by Rabinarayan Satpathy and published by John Wiley & Sons. This book was released on 2021-01-20 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel machine learning computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics approximating classification and prediction of disease, feature selection, dimensionality reduction, gene selection and classification of microarray data and many more.

Advanced AI Techniques and Applications in Bioinformatics

Author : Loveleen Gaur
Publisher : CRC Press
ISBN 13 : 100046301X
Total Pages : 220 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Advanced AI Techniques and Applications in Bioinformatics by : Loveleen Gaur

Download or read book Advanced AI Techniques and Applications in Bioinformatics written by Loveleen Gaur and published by CRC Press. This book was released on 2021-10-17 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advanced AI techniques are essential for resolving various problematic aspects emerging in the field of bioinformatics. This book covers the recent approaches in artificial intelligence and machine learning methods and their applications in Genome and Gene editing, cancer drug discovery classification, and the protein folding algorithms among others. Deep learning, which is widely used in image processing, is also applicable in bioinformatics as one of the most popular artificial intelligence approaches. The wide range of applications discussed in this book are an indispensable resource for computer scientists, engineers, biologists, mathematicians, physicians, and medical informaticists. Features: Focusses on the cross-disciplinary relation between computer science and biology and the role of machine learning methods in resolving complex problems in bioinformatics Provides a comprehensive and balanced blend of topics and applications using various advanced algorithms Presents cutting-edge research methodologies in the area of AI methods when applied to bioinformatics and innovative solutions Discusses the AI/ML techniques, their use, and their potential for use in common and future bioinformatics applications Includes recent achievements in AI and bioinformatics contributed by a global team of researchers

Bioinformatics and Medical Applications

Author : A. Suresh
Publisher : John Wiley & Sons
ISBN 13 : 1119791839
Total Pages : 356 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Bioinformatics and Medical Applications by : A. Suresh

Download or read book Bioinformatics and Medical Applications written by A. Suresh and published by John Wiley & Sons. This book was released on 2022-04-12 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: BIOINFORMATICS AND MEDICAL APPLICATIONS The main topics addressed in this book are big data analytics problems in bioinformatics research such as microarray data analysis, sequence analysis, genomics-based analytics, disease network analysis, techniques for big data analytics, and health information technology. Bioinformatics and Medical Applications: Big Data Using Deep Learning Algorithms analyses massive biological datasets using computational approaches and the latest cutting-edge technologies to capture and interpret biological data. The book delivers various bioinformatics computational methods used to identify diseases at an early stage by assembling cutting-edge resources into a single collection designed to enlighten the reader on topics focusing on computer science, mathematics, and biology. In modern biology and medicine, bioinformatics is critical for data management. This book explains the bioinformatician’s important tools and examines how they are used to evaluate biological data and advance disease knowledge. The editors have curated a distinguished group of perceptive and concise chapters that presents the current state of medical treatments and systems and offers emerging solutions for a more personalized approach to healthcare. Applying deep learning techniques for data-driven solutions in health information allows automated analysis whose method can be more advantageous in supporting the problems arising from medical and health-related information. Audience The primary audience for the book includes specialists, researchers, postgraduates, designers, experts, and engineers, who are occupied with biometric research and security-related issues.

Handbook of Statistical Bioinformatics

Author : Henry Horng-Shing Lu
Publisher : Springer Nature
ISBN 13 : 3662659026
Total Pages : 406 pages
Book Rating : 4.6/5 (626 download)

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Book Synopsis Handbook of Statistical Bioinformatics by : Henry Horng-Shing Lu

Download or read book Handbook of Statistical Bioinformatics written by Henry Horng-Shing Lu and published by Springer Nature. This book was released on 2022-12-08 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, this handbook collects authoritative contributions on modern methods and tools in statistical bioinformatics with a focus on the interface between computational statistics and cutting-edge developments in computational biology. The three parts of the book cover statistical methods for single-cell analysis, network analysis, and systems biology, with contributions by leading experts addressing key topics in probabilistic and statistical modeling and the analysis of massive data sets generated by modern biotechnology. This handbook will serve as a useful reference source for students, researchers and practitioners in statistics, computer science and biological and biomedical research, who are interested in the latest developments in computational statistics as applied to computational biology.

Machine Learning in Bioinformatics

Author : Yanqing Zhang
Publisher : John Wiley & Sons
ISBN 13 : 0470397411
Total Pages : 476 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Machine Learning in Bioinformatics by : Yanqing Zhang

Download or read book Machine Learning in Bioinformatics written by Yanqing Zhang and published by John Wiley & Sons. This book was released on 2009-02-23 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to machine learning methods and their applications to problems in bioinformatics Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. From an internationally recognized panel of prominent researchers in the field, Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics. Coverage includes: feature selection for genomic and proteomic data mining; comparing variable selection methods in gene selection and classification of microarray data; fuzzy gene mining; sequence-based prediction of residue-level properties in proteins; probabilistic methods for long-range features in biosequences; and much more. Machine Learning in Bioinformatics is an indispensable resource for computer scientists, engineers, biologists, mathematicians, researchers, clinicians, physicians, and medical informaticists. It is also a valuable reference text for computer science, engineering, and biology courses at the upper undergraduate and graduate levels.

Computational Biology and Machine Learning for Metabolic Engineering and Synthetic Biology

Author : Kumar Selvarajoo
Publisher : Springer Nature
ISBN 13 : 1071626175
Total Pages : 457 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Computational Biology and Machine Learning for Metabolic Engineering and Synthetic Biology by : Kumar Selvarajoo

Download or read book Computational Biology and Machine Learning for Metabolic Engineering and Synthetic Biology written by Kumar Selvarajoo and published by Springer Nature. This book was released on 2022-10-13 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides protocols for computational, statistical, and machine learning methods that are mainly applied to the study of metabolic engineering, synthetic biology, and disease applications. These techniques support the latest progress in cross-disciplinary research that integrates the different scales of biological complexity. The topics covered in this book are geared toward researchers with a background in engineering, computational analytical, and modeling experience and cover a broad range of topics in computational and machine learning approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Computational Biology and Machine Learning for Metabolic Engineering and Synthetic Biology is a valuable resource for any researcher or scientist who wants to learn more about the latest computational methods and how they are applied toward the understanding and prediction of complex biology.

Bioinformatics

Author : Pierre Baldi
Publisher : MIT Press (MA)
ISBN 13 : 9780262024426
Total Pages : 351 pages
Book Rating : 4.0/5 (244 download)

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Book Synopsis Bioinformatics by : Pierre Baldi

Download or read book Bioinformatics written by Pierre Baldi and published by MIT Press (MA). This book was released on 1998 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: An unprecedented wealth of data is being generated by genome sequencing projects and other experimental efforts to determine the structure and function of biological molecules. The demands and opportunities for interpreting these data are expanding more than ever. Biotechnology, pharmacology, and medicine will be particularly affected by the new results and the increased understanding of life at the molecular level. Bioinformatics is the development and application of computer methods for analysis, interpretation, and prediction, as well as for the design of experiments. It has emerged as a strategic frontier between biology and computer science. Machine learning approaches (e.g., neural networks, hidden Markov models, and belief networks) are ideally suited for areas where there is a lot of data but little theory—and this is exactly the situation in molecular biology. As with its predecessor, statistical model fitting, the goal in machine learning is to extract useful information from a body of data by building good probabilistic models. The particular twist behind machine learning, however, is to automate the process as much as possible. In this book, Pierre Baldi and Soren Brunak present the key machine learning approaches and apply them to the computational problems encountered in the analysis of biological data. The book is aimed at two types of researchers and students. First are the biologists and biochemists who need to understand new data-driven algorithms, such as neural networks and hidden Markov models, in the context of biological sequences and their molecular structure and function. Second are those with a primary background in physics, mathematics, statistics, or computer science who need to know more about specific applications in molecular biology.

Modelling and Machine Learning Methods for Bioinformatics and Data Science Applications

Author : Monica Bianchini
Publisher : Mdpi AG
ISBN 13 : 9783036528403
Total Pages : 102 pages
Book Rating : 4.5/5 (284 download)

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Book Synopsis Modelling and Machine Learning Methods for Bioinformatics and Data Science Applications by : Monica Bianchini

Download or read book Modelling and Machine Learning Methods for Bioinformatics and Data Science Applications written by Monica Bianchini and published by Mdpi AG. This book was released on 2022-01-12 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical modeling is routinely used in physical and engineering sciences to help understand complex systems and optimize industrial processes. Mathematical modeling differs from Artificial Intelligence because it does not exclusively use the collected data to describe an industrial phenomenon or process, but it is based on fundamental laws of physics or engineering that lead to systems of equations able to represent all the variables that characterize the process. Conversely, Machine Learning methods require a large amount of data to find solutions, remaining detached from the problem that generated them and trying to infer the behavior of the object, material or process to be examined from observed samples. Mathematics allows us to formulate complex models with effectiveness and creativity, describing nature and physics. Together with the potential of Artificial Intelligence and data collection techniques, a new way of dealing with practical problems is possible. The insertion of the equations deriving from the physical world in the data-driven models can in fact greatly enrich the information content of the sampled data, allowing to simulate very complex phenomena, with drastically reduced calculation times. Combined approaches will constitute a breakthrough in cutting-edge applications, providing precise and reliable tools for the prediction of phenomena in biological macro/microsystems, for biotechnological applications and for medical diagnostics, particularly in the field of precision medicine.

Bioinformatics, second edition

Author : Pierre Baldi
Publisher : MIT Press
ISBN 13 : 9780262025065
Total Pages : 492 pages
Book Rating : 4.0/5 (25 download)

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Book Synopsis Bioinformatics, second edition by : Pierre Baldi

Download or read book Bioinformatics, second edition written by Pierre Baldi and published by MIT Press. This book was released on 2001-07-20 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to machine learning approaches and their application to the analysis of biological data. An unprecedented wealth of data is being generated by genome sequencing projects and other experimental efforts to determine the structure and function of biological molecules. The demands and opportunities for interpreting these data are expanding rapidly. Bioinformatics is the development and application of computer methods for management, analysis, interpretation, and prediction, as well as for the design of experiments. Machine learning approaches (e.g., neural networks, hidden Markov models, and belief networks) are ideally suited for areas where there is a lot of data but little theory, which is the situation in molecular biology. The goal in machine learning is to extract useful information from a body of data by building good probabilistic models—and to automate the process as much as possible. In this book Pierre Baldi and Søren Brunak present the key machine learning approaches and apply them to the computational problems encountered in the analysis of biological data. The book is aimed both at biologists and biochemists who need to understand new data-driven algorithms and at those with a primary background in physics, mathematics, statistics, or computer science who need to know more about applications in molecular biology. This new second edition contains expanded coverage of probabilistic graphical models and of the applications of neural networks, as well as a new chapter on microarrays and gene expression. The entire text has been extensively revised.