Applications of Mass Spectrometry in Life Safety

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Publisher : Springer Science & Business Media
ISBN 13 : 1402088116
Total Pages : 238 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Applications of Mass Spectrometry in Life Safety by : Crisan Popescu

Download or read book Applications of Mass Spectrometry in Life Safety written by Crisan Popescu and published by Springer Science & Business Media. This book was released on 2008-09-02 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry (MS) along with its hyphenated techniques is capable of high throughput, sensitivity, accuracy and selectivity for the analysis of structure and composition of almost any product. Like in electrophoresis, MS separates mo- cules based on the mass-to-charge ratio. In case of gel electrophoresis (SDS- PAGE), a well-known and efficient bioanalytical technique, proteins bear negative charges but have the same charge density, so proteins are separated according to their size. Similarly, in case of MS analysis, proteins carry the same charge, and are separated by their molecular weight. Unlike SDS-PAGE, however, modern ultra high resolution MS discerns very small mass differences and can resolve and completely identify in a single experiment species of the same nominal mass in complex biological mixtures. Consequently, MS can be used for the structural characterization, identification and sensitive detection of mixtures of biomolecules or for assessing the quality of isolated proteins (purity, integrity, or post-translational modifications, for example), carbohydrates, nucleic acids, drugs, metabolites, pollutants etc. In the post-genome era, MS is continuously developing as one of the most re- able analytical method for elucidating the structure of molecules originating from various biological matrices. The potential of MS for high-sensitive structural a- lyses became unsurpassable after the introduction of electrospray (ESI) and matrix assisted laser/desorption ionization (MALDI) methods, on one hand, and the pos- bility to deduce in detail unknown biopolymer structures by highly accurate mo- cular mass measurement followed by sequencing using dissociation techniques based on multiple stage MS, on the other.

Medical Applications of Mass Spectrometry

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Author :
Publisher : Elsevier
ISBN 13 : 0080554652
Total Pages : 607 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Medical Applications of Mass Spectrometry by : Karoly Vekey

Download or read book Medical Applications of Mass Spectrometry written by Karoly Vekey and published by Elsevier. This book was released on 2011-08-11 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging.* Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.* Guides the reader from basic principles and methods to cutting edge applications.* There is NO comparable book on the market to fill this fast growing field.

Introduction to Mass Spectrometry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118681584
Total Pages : 972 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Introduction to Mass Spectrometry by : J. Throck Watson

Download or read book Introduction to Mass Spectrometry written by J. Throck Watson and published by John Wiley & Sons. This book was released on 2013-07-09 with total page 972 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry

Mass Spectrometry

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Author :
Publisher : Wiley
ISBN 13 : 9780471485650
Total Pages : 420 pages
Book Rating : 4.4/5 (856 download)

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Book Synopsis Mass Spectrometry by : Edmond de Hoffmann

Download or read book Mass Spectrometry written by Edmond de Hoffmann and published by Wiley. This book was released on 2001-10-10 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is extensively updated including new techniques and applications. All instrumental aspects of mass spectrometry are clearly and concisely described; sources, analysers and detectors. * Revised and updated * Numerous examples and illustrations are combined with a series of exercises to help encourage student understanding * Includes biological applications, which have been significantly expanded and updated * Also includes coverage of ESI and MALDI

Applications of Modern Mass Spectrometry

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Publisher :
ISBN 13 : 9789811433818
Total Pages : 227 pages
Book Rating : 4.4/5 (338 download)

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Book Synopsis Applications of Modern Mass Spectrometry by : Atta-ur-Rahman

Download or read book Applications of Modern Mass Spectrometry written by Atta-ur-Rahman and published by . This book was released on 2020-07-02 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Modern Mass Spectrometry covers the latest advances in the use of mass spectrometry inscientific research. The series attempts to present readers information on thebroad range of mass spectrometry techniques and configurations, data analysisand practical applications. Each volume contains contributions from eminentresearchers who present their findings in an easy to read format. Themultidisciplinary nature of the works presented in each volume of this bookseries make it a valuable reference on mass spectrometry to academicresearchers and industrial R&D specialists in applied sciences,biochemistry, life sciences and allied fields. The first volume of the series presents 5 reviews:- Applications of mass spectrometry for the determination of themicrobial crude protein synthesis in ruminants- Qualitative and quantitative LC-MS analysis in food proteins andpeptides- Chemometrics as a powerful and complementary tool for massspectrometry applications in life sciences- Recent developments of allied techniques of qualitative analysis ofheavy metal ions in aqueous solutions with special reference to modern massspectrometry- New techniques and methods in explosive analysis

Applications in High Resolution Mass Spectrometry

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Publisher : Elsevier
ISBN 13 : 0128096489
Total Pages : 362 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Applications in High Resolution Mass Spectrometry by : Roberto Romero-González

Download or read book Applications in High Resolution Mass Spectrometry written by Roberto Romero-González and published by Elsevier. This book was released on 2017-03-07 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of High Resolution Mass Spectrometry: Food Safety and Pesticide Residue Analysis is the first book to offer complete coverage of all aspects of high resolution mass spectrometry (HRMS) used for the analysis of pesticide residue in food. Aimed at researchers and graduate students in food safety, toxicology, and analytical chemistry, the book equips readers with foundational knowledge of HRMS, including established and state-of-the-art principles and analysis strategies. Additionally, it provides a roadmap for implementation, including discussions of the latest instrumentation and software available. Detailed coverage is given to the application of HRMS coupled to ultra high-performance liquid chromatography (UHPLC-HRMS) in the analysis of pesticide residue in fruits and vegetables and food from animal origin. The book also discusses extraction procedures and the challenges of sample preparation, gas chromatography coupled to high resolution mass spectrometry, flow injection-HRMS, ambient ionization, and identification of pesticide transformation products in food. Responding to the fast development and application of these new procedures, this book is an essential resource in the food safety field. - Arms researchers with an in-depth resource devoted to the rapid advances in HRMS tools and strategies for pesticide residue analysis in food - Provides a complete overview of analytical methodologies and applications of HRMS, including UHPLC-HRMS, HRMS coupled with time of flight (TOF) and/or GC-Orbitrap, and flow injection-HRMS - Discusses the current international regulations and legislation related to the use of HRMS in pesticide residue analysis - Features a chapter on the hardware and software available for HRMS implementation - Offers separate chapters on HRMS applied to pesticide residue analysis in fruits and vegetables and in food from animal origin

Mass Spectrometry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118681940
Total Pages : 502 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Mass Spectrometry by : Edmond de Hoffmann

Download or read book Mass Spectrometry written by Edmond de Hoffmann and published by John Wiley & Sons. This book was released on 2013-04-03 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra. This new edition has been thoroughly revised and updated and has been redesigned to give the book a more contemporary look. As with previous editions it contains numerous examples, references and a series of exercises of increasing difficulty to encourage student understanding. Updates include: Increased coverage of MALDI and ESI, more detailed description of time of flight spectrometers, new material on isotope ratio mass spectrometry, and an expanded range of applications. Mass Spectrometry, Third Edition is an invaluable resource for all undergraduate and postgraduate students using this technique in departments of chemistry, biochemistry, medicine, pharmacology, agriculture, material science and food science. It is also of interest for researchers looking for an overview of the latest techniques and developments.

Ambient Ionization Mass Spectrometry in Life Sciences

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Publisher : Elsevier
ISBN 13 : 0128172215
Total Pages : 294 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Ambient Ionization Mass Spectrometry in Life Sciences by : Kei Zaitsu

Download or read book Ambient Ionization Mass Spectrometry in Life Sciences written by Kei Zaitsu and published by Elsevier. This book was released on 2019-11-06 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ambient Ionization Mass Spectrometry in Life Sciences: Principles and Applications is a systematic introduction to this rapidly expanding area of study. Underlying principles of each technique are explained in detail, along with discussions on their applications across life science disciplines. Ambient ionization has recently emerged as one of the hottest and fastest growing topics in mass spectrometry, hence this book is not just for analysts and researchers who use and study mass spectrometry. This volume would be of interest to anyone who works in or studies analytical chemistry, omics sciences (including metabolomics), pharmacokinetics, forensic science or drug analysis. - Covers the most up-to-date techniques, including DART, DCBI, DESI, PESI, PSI, REIMS and laser-based ambient ionization - Includes easy-to-understand pros and cons of each ionization technique to aid in decision-making - Provides plentiful examples of life science applications

Advancements of Mass Spectrometry in Biomedical Research

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Publisher : Springer
ISBN 13 : 3319060686
Total Pages : 601 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Advancements of Mass Spectrometry in Biomedical Research by : Alisa G. Woods

Download or read book Advancements of Mass Spectrometry in Biomedical Research written by Alisa G. Woods and published by Springer. This book was released on 2014-06-20 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.

Mass Spectrometry Method Development and Application of Investigation of Food Safety and Human Health

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Publisher :
ISBN 13 :
Total Pages : 229 pages
Book Rating : 4.:/5 (122 download)

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Book Synopsis Mass Spectrometry Method Development and Application of Investigation of Food Safety and Human Health by : Guodong Cao

Download or read book Mass Spectrometry Method Development and Application of Investigation of Food Safety and Human Health written by Guodong Cao and published by . This book was released on 2020 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advanced Mass Spectrometry

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Publisher : Elsevier
ISBN 13 : 1483188876
Total Pages : 156 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Advanced Mass Spectrometry by : Urs P. Schlunegger

Download or read book Advanced Mass Spectrometry written by Urs P. Schlunegger and published by Elsevier. This book was released on 2016-01-22 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Mass Spectrometry: Applications in Organic and Analytical Chemistry discusses the concepts that are essential in the effective utilization of mass spectrometry. The title particularly covers the fundamentals of the modern techniques, along with the technological concerns of mass spectrometry. The opening chapter of the selection introduces mass spectrometry, while the subsequent chapters cover the fundamentals and hardware. The next chapters talk about the analytical chemistry consequences and the ion-genetic relationships. The remaining chapter covers the application of mass spectrometry, which includes structural, mechanistic, chemical, and biochemical applications. The book will be of great use to organic and analytical chemists. Chemists from other branch of chemistry, along with practitioners of related fields such as chemical engineering will also benefit from the text.

Advanced Mass Spectrometry for Food Safety and Quality

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Author :
Publisher : Elsevier
ISBN 13 : 0444633928
Total Pages : 733 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Advanced Mass Spectrometry for Food Safety and Quality by :

Download or read book Advanced Mass Spectrometry for Food Safety and Quality written by and published by Elsevier. This book was released on 2015-05-08 with total page 733 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Mass Spectrometry for Food Safety and Quality provides information on recent advancements made in mass spectrometry-based techniques and their applications in food safety and quality, also covering the major challenges associated with implementing these technologies for more effective identification of unknown compounds, food profiling, or candidate biomarker discovery. Recent advances in mass spectrometry technologies have uncovered tremendous opportunities for a range of food-related applications. However, the distinctive characteristics of food, such as the wide range of the different components and their extreme complexity present enormous challenges. This text brings together the most recent data on the topic, providing an important resource towards greater food safety and quality. - Presents critical applications for a sustainable, affordable and safe food supply - Covers emerging problems in food safety and quality with many specific examples. - Encompasses the characteristics, advantages, and limitations of mass spectrometry, and the current strategies in method development and validation - Provides the most recent data on the important topic of food safety and quality

Forensic Applications of Mass Spectrometry

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Author :
Publisher : CRC Press
ISBN 13 : 1000141713
Total Pages : 314 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Forensic Applications of Mass Spectrometry by : Jehuda Yinon

Download or read book Forensic Applications of Mass Spectrometry written by Jehuda Yinon and published by CRC Press. This book was released on 2020-11-25 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic Applications of Mass Spectrometry combines the most current developments in applications of mass spectrometry techniques to forensic analyses. The techniques discussed include: capillary-GC/MS thermospray-LC/MS tandem mass spectrometry (MS/MS) pyrolysis-GC/MS isotope ratio mass spectrometry The applications include: analysis of body fluids and hair for drugs of abuse drug testing in sports analysis of accelerants in fire debris detection of hidden explosives in luggage and mail identification of explosives in post-explosion debris examination of evidential materials (paints, fibers, synthetic polymers) authentication of regulated products (flavoring substances, fruit juices) protection of industrial products by isotopic signature

Mass Spectrometry

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Publisher : John Wiley & Sons
ISBN 13 : 047039580X
Total Pages : 358 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Mass Spectrometry by : Agnieszka Kraj

Download or read book Mass Spectrometry written by Agnieszka Kraj and published by John Wiley & Sons. This book was released on 2008-12-01 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions from noted experts from Europe and North America, Mass Spectrometry Instrumentation, Interpretation, and Applications serves as a forum to introduce students to the whole world of mass spectrometry and to the many different perspectives that each scientific field brings to its use. The book emphasizes the use of this important analytical technique in many different fields, including applications for organic and inorganic chemistry, forensic science, biotechnology, and many other areas. After describing the history of mass spectrometry, the book moves on to discuss instrumentation, theory, and basic applications.

Application of Mass Spectrometry in Food Safety and Quality Means of Target and Untargeted Approaches

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis Application of Mass Spectrometry in Food Safety and Quality Means of Target and Untargeted Approaches by : Francesca Di Ottavio

Download or read book Application of Mass Spectrometry in Food Safety and Quality Means of Target and Untargeted Approaches written by Francesca Di Ottavio and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mass Spectrometry in Food Safety

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Author :
Publisher : Humana Press
ISBN 13 : 9781617791352
Total Pages : 416 pages
Book Rating : 4.7/5 (913 download)

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Book Synopsis Mass Spectrometry in Food Safety by : Jerry Zweigenbaum

Download or read book Mass Spectrometry in Food Safety written by Jerry Zweigenbaum and published by Humana Press. This book was released on 2011-06-10 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a key component of human survival, a safe and sufficient food supply is essential for a healthy and productive population throughout the world, so assurance that the food supply is clean and free of harmful substances is a global concern. In Mass Spectrometry in Food Safety: Methods and Protocols, experts in the field provide context to the subject through reviews of regulations in various countries, the current state-of-the art, and specific, detailed scientific methods being employed today. The volume thoroughly covers the key areas in food safety, such as detection of low level chemical residues, pesticide analysis aided by chromatographic techniques, and the revealing of mycotoxins and chemical contaminants from packaging materials. Written in the highly successful Methods in Molecular BiologyTM series format, method chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Pertinent and cutting-edge, Mass Spectrometry in Food Safety: Methods and Protocols serves researchers with both understanding and appreciation for the contribution of mass spectrometry and its vital application to food testing and food safety.

Forensic Science

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Publisher : John Wiley & Sons
ISBN 13 : 3527693548
Total Pages : 446 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Forensic Science by : Evgeny Katz

Download or read book Forensic Science written by Evgeny Katz and published by John Wiley & Sons. This book was released on 2016-03-08 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concentrating on the natural science aspects of forensics, top international authors from renowned universities, institutes, and laboratories impart the latest information from the field. In doing so they provide the background needed to understand the state of the art in forensic science with a focus on biological, chemical, biochemical, and physical methods. The broad subject coverage includes spectroscopic analysis techniques in various wavelength regimes, gas chromatography, mass spectrometry, electrochemical detection approaches, and imaging techniques, as well as advanced biochemical, DNA-based identification methods. The result is a unique collection of hard-to-get data that is otherwise only found scattered throughout the literature.