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Application And Innovation Of Multiomics Technologies In Clinical Oncology
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Book Synopsis Application and Innovation of Multiomics Technologies in Clinical Oncology by : Ye Wang
Download or read book Application and Innovation of Multiomics Technologies in Clinical Oncology written by Ye Wang and published by Frontiers Media SA. This book was released on 2023-04-26 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Evolution of Translational Omics by : Institute of Medicine
Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
Book Synopsis Research and Clinical Applications of Targeting Gastric Neoplasms by : Brendan Jenkins
Download or read book Research and Clinical Applications of Targeting Gastric Neoplasms written by Brendan Jenkins and published by Academic Press. This book was released on 2021-07-17 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research and Clinical Applications of Targeting Gastric Neoplasms provides a comprehensive overview of gastrointestinal cancers, covering preclinical research and clinical findings related to risk factors, current treatment regimens (including immunotherapy), screening/detection methods, etiology of disease, precision medicine and future perspectives. Gastrointestinal cancers rank among the most lethal and common worldwide, and as such, there is intense research into their diverse causes and treatment options. This reference provides a consolidation of the research, making it a perfect resource for basic science and clinical researchers as well as oncologists who work in gastroenterology and GI tract cancer fields. - Provides comprehensive coverage of preclinical research and the clinical aspects of gastric cancer - Presents future perspectives from leading researchers in the field who provide the potential for furthering research topics - Combines the expertise of researchers in GI tracts, cancer, immunity, immunology, infectious disease and microbiology for an interdisciplinary approach
Book Synopsis Molecular Medicine by : Sinem Nalbantoglu
Download or read book Molecular Medicine written by Sinem Nalbantoglu and published by BoD – Books on Demand. This book was released on 2019-11-06 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular medicine is an applied science focused on human genes/transcripts, proteins, metabolites, and metabolic networks that describes molecular and cellular processes of health and disease onset and progression. Molecular medicine-based integrative identification and characterization of biomarker targets and their clinical translations is essential to explain/decipher the mechanism(s) underlying physiological pathways and pathological conditions, and acquire cell-targeted early interventional and therapeutic strategies in the context of precision medicine and public health. Principally, Molecular Medicine provides an overview of the latest headlines/developments of systems and molecular medicine, highlighting the emerging high-throughput technologies, promising potential applications, and progress in biomedical research and development strategies.
Download or read book Cytogenomics written by Thomas Liehr and published by Academic Press. This book was released on 2021-05-25 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century. After an introduction to (molecular) cytogenetics, being the basic of all cytogenomic research, this book highlights the strengths and newfound advantages of cytogenomic research methods and technologies, enabling researchers to jump-start their own projects and more effectively gather and interpret chromosomal data. Methods discussed include banding and molecular cytogenetics, molecular combing, molecular karyotyping, next-generation sequencing, epigenetic study approaches, optical mapping/karyomapping, and CRISPR-cas9 applications for cytogenomics. The book's second half demonstrates recent applications of cytogenomic techniques, such as characterizing 3D chromosome structure across different tissue types and insights into multilayer organization of chromosomes, role of repetitive elements and noncoding RNAs in human genome, studies in topologically associated domains, interchromosomal interactions, and chromoanagenesis. This book is an important reference source for researchers, students, basic and translational scientists, and clinicians in the areas of human genetics, genomics, reproductive medicine, gynecology, obstetrics, internal medicine, oncology, bioinformatics, medical genetics, and prenatal testing, as well as genetic counselors, clinical laboratory geneticists, bioethicists, and fertility specialists. - Offers applied approaches empowering a new generation of cytogenomic research using a balanced combination of classical and advanced technologies - Provides a framework for interpreting chromosome structure and how this affects the functioning of the genome in health and disease - Features chapter contributions from international leaders in the field
Book Synopsis Multi-Omics Analysis of the Human Microbiome by : Indra Mani
Download or read book Multi-Omics Analysis of the Human Microbiome written by Indra Mani and published by Springer Nature. This book was released on with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Proceedings of Third International Conference in Mechanical and Energy Technology by : Sanjay Yadav
Download or read book Proceedings of Third International Conference in Mechanical and Energy Technology written by Sanjay Yadav and published by Springer Nature. This book was released on with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis AI-Driven Innovations in Digital Healthcare: Emerging Trends, Challenges, and Applications by : Khang, Alex
Download or read book AI-Driven Innovations in Digital Healthcare: Emerging Trends, Challenges, and Applications written by Khang, Alex and published by IGI Global. This book was released on 2024-02-09 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the healthcare sector, a pressing need for transformative changes is growing. From chronic diseases to complex diagnostic procedures, the industry stands at the crossroads of technological innovation and a burgeoning demand for more efficient, precise interventions. Patient expectations are soaring, and the deluge of medical data is overwhelming traditional healthcare systems. It is within this challenging environment that AI-Driven Innovations in Digital Healthcare: Emerging Trends, Challenges, and Applications emerges as a beacon of insight and practical solutions. The traditional healthcare framework is struggling to keep pace with the diverse demands of patients and the ever-expanding volume of medical data. As diseases become more intricate, attempts to provide timely identification and precise treatment of ailments become increasingly elusive. The urgency for a paradigm shift in healthcare delivery is emphasized by the critical need for early interventions, particularly in disease prediction. This challenge necessitates a holistic approach that harnesses the power of artificial intelligence (AI) and innovative technologies to steer healthcare toward a more responsive and patient-centric future.
Book Synopsis Computational Methods for Multi-Omics Data Analysis in Cancer Precision Medicine by : Ehsan Nazemalhosseini-Mojarad
Download or read book Computational Methods for Multi-Omics Data Analysis in Cancer Precision Medicine written by Ehsan Nazemalhosseini-Mojarad and published by Frontiers Media SA. This book was released on 2023-08-02 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a complex and heterogeneous disease often caused by different alterations. The development of human cancer is due to the accumulation of genetic and epigenetic modifications that could affect the structure and function of the genome. High-throughput methods (e.g., microarray and next-generation sequencing) can investigate a tumor at multiple levels: i) DNA with genome-wide association studies (GWAS), ii) epigenetic modifications such as DNA methylation, histone changes and microRNAs (miRNAs) iii) mRNA. The availability of public datasets from different multi-omics data has been growing rapidly and could facilitate better knowledge of the biological processes of cancer. Computational approaches are essential for the analysis of big data and the identification of potential biomarkers for early and differential diagnosis, and prognosis.
Book Synopsis Advances in methods and tools for multi-omics data analysis by : Ornella Cominetti
Download or read book Advances in methods and tools for multi-omics data analysis written by Ornella Cominetti and published by Frontiers Media SA. This book was released on 2023-05-12 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cross-Disciplinary Perspectives on Negative Emotions and Cancer Risk by : Eliyah Oren
Download or read book Cross-Disciplinary Perspectives on Negative Emotions and Cancer Risk written by Eliyah Oren and published by Academia Pundarika. This book was released on 2024-07-20 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unleash the Secrets of Negative Emotions and Cancer: A Revolutionary Approach to Prevention and Treatment Have you ever wondered if your negative emotions could be affecting your health? The startling truth is that a growing body of research now links chronic stress, anxiety, and depression to an increased risk of cancer! In this groundbreaking book, Cross-Disciplinary Perspectives on Negative Emotions and Cancer Risk: Innovations in Prevention and Treatment from Neurobiology and Fasciology, we embark on an eye-opening journey to uncover how negative emotions influence cancer risk! You will discover: * How stress hijacks the brain, disrupts the immune system, and creates a breeding ground for cancer? * How fascia, the body's hidden connective tissue network, emerges as the missing link between negative emotions and cancer? * Can changing your mindset and managing stress truly help you stay cancer-free? * How cutting-edge research in neurobiology and fasciology is revolutionizing cancer prevention and treatment? This book will shatter your conventional understanding of cancer and provide you with: * Science-backed, innovative therapies to effectively manage negative emotions and lower cancer risk! * A holistic, inside-out approach to cancer prevention! * Immunity-boosting strategies to build a robust body and ward off cancer! If you're ready to break free from the shackles of negative emotions or seeking a more comprehensive approach to cancer prevention, this groundbreaking book is for you! Grab your copy of Cross-Disciplinary Perspectives on Negative Emotions and Cancer Risk: Innovations in Prevention and Treatment from Neurobiology and Fasciology today and unlock the door to a healthier you!
Book Synopsis The Application of Sequencing Technologies and Bioinformatics Methods in Cancer Biology by : Geng Chen
Download or read book The Application of Sequencing Technologies and Bioinformatics Methods in Cancer Biology written by Geng Chen and published by Frontiers Media SA. This book was released on 2022-10-17 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cancer Evolution by : Charles Swanton
Download or read book Cancer Evolution written by Charles Swanton and published by Perspectives Cshl. This book was released on 2017 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer.
Book Synopsis Biological Insights of Multi-Omics Technologies in Human Diseases by : Aarif Ali
Download or read book Biological Insights of Multi-Omics Technologies in Human Diseases written by Aarif Ali and published by Elsevier. This book was released on 2024-05-23 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Biological Insights of Multi-Omics Technologies in Human Diseases ́ provides detailed information about the basics of multi-omic technologies including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharmaceutical, socio-ethical, and economic perspectives. The chapters are designed in a well-defined chronology such that readers will intuitively understand the central idea. This book is an ideal resource for health professionals, scientists and researchers, nutritionists, health practitioners, students, and all those who wish to broaden their knowledge in the allied field. • Explains the in-depth role of multi-omics on drug discovery/metabolism, diseases, and highlights progress in both the research and clinical areas of computation, as well as relevant implementation experience and challenges. • Describes the practice of multi-omic technologies in the treatment of several diseases.• Includes practical application and machine learning approaches of multi-omics.
Book Synopsis Bio-Inspired Computing: Theories and Applications by : Linqiang Pan
Download or read book Bio-Inspired Computing: Theories and Applications written by Linqiang Pan and published by Springer Nature. This book was released on 2021-03-31 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume constitutes the revised selected papers of the 15th International Conference on Bio-inspired Computing: Theories and Applications, BIC-TA 2020, held in Qingdao, China, in October 2020. The 43 full papers presented in both volumes were selected from 109 submissions. The papers are organized according to the topical headings: evolutionary computation and swarm intelligence; neural networks and machine learning; DNA computing and membrane computing.
Book Synopsis Bioinformatics Research and Applications by : Wei Peng
Download or read book Bioinformatics Research and Applications written by Wei Peng and published by Springer Nature. This book was released on 2024 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 20th International Symposium on Bioinformatics Research and Applications, ISBRA 2024, held in Kunming, China, in July 19-21, 2024. The 93 full papers included in this book were carefully reviewed and selected from 236 submissions. The symposium provides a forum for the exchange of ideas and results among researchers, developers, and practitioners working on all aspects of bioinformatics and computational biology and their applications.
Book Synopsis Engineering Technologies and Clinical Translation by : Mansoor M. Amiji
Download or read book Engineering Technologies and Clinical Translation written by Mansoor M. Amiji and published by Academic Press. This book was released on 2021-08-25 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Engineering Technologies and Clinical Translation: Volume 3: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies, focusing specifically on the development of solutions for drug delivery and its clinical outcomes. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. This volume of Delivery Strategies and Engineering Technologies in Cancer Immunotherapy discusses biomaterial, microfluidic, and biodegradable devices, engineered microbes, personalized medicine, clinical approval process, and many other IO technologies. Engineering Technologies and Clinical Translation: Volume 3: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. - Explores engineering technologies and their clinical translation in a comprehensive way - Presents forecasting on the future of nanotechnology and drug delivery for IO - Engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side
