Antithrombotic Drugs In Thrombosis Models

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Antithrombotic Drugs in Thrombosis Models

Author : Josef Hladovec
Publisher : CRC Press
ISBN 13 : 1000141683
Total Pages : 248 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Antithrombotic Drugs in Thrombosis Models by : Josef Hladovec

Download or read book Antithrombotic Drugs in Thrombosis Models written by Josef Hladovec and published by CRC Press. This book was released on 2020-11-25 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antithrombotic Drugs in Thrombosis Models presents a critical review of the use of thrombosis models and an original, highly sensitive methodology for testing antithrombotics based on a more adequate understanding of thrombotic processes. The methods form an integrated system stressing particularly the plurifactorial and global character of thrombosis and the key role of a generalized mild endothelial lesion. Packed with illustrations, this book documents the effectiveness of the system through the screening of a series of acknowledged and potential antithrombotics, and includes a unique study of their mutual combinations. Special emphasis is placed on the importance of biomodels for preliminary testing of antithrombotics. This book is particularly useful to researchers in pharmacology and the pharmaceutical industry; however, those interested in drug research and the field of cardiovascular medicine will benefit as well.

Anticoagulants, Antiplatelets, and Thrombolytics

Author : Shaker A. Mousa
Publisher : Springer Science & Business Media
ISBN 13 : 1592596584
Total Pages : 310 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Anticoagulants, Antiplatelets, and Thrombolytics by : Shaker A. Mousa

Download or read book Anticoagulants, Antiplatelets, and Thrombolytics written by Shaker A. Mousa and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of review articles highlights the latest development of antithrombotics and provides proven experimental methods for the further development of new and improved anticoagulants. Among the cutting-edge developments reviewed are the novel usage of low molecular weight heparins, such antithrombin agents as the hirudin, and such antiplatelet drugs as the GPIIb/IIIa inhibitors and ADP receptor antagonists.

Anticoagulant Drugs

Author : Mojca Božič-Mijovski
Publisher : BoD – Books on Demand
ISBN 13 : 1789236223
Total Pages : 122 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Anticoagulant Drugs by : Mojca Božič-Mijovski

Download or read book Anticoagulant Drugs written by Mojca Božič-Mijovski and published by BoD – Books on Demand. This book was released on 2018-08-29 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anticoagulant drugs are among the most frequently prescribed drugs in everyday clinical practice. In the past decades, several new direct oral anticoagulants were developed that changed the anticoagulant therapy landscape considerably. This book provides an extensive overview of all the known anticoagulants that can be useful for studying different aspects of the haemostatic system or as a starting point for new drug development. It is also a valuable tool for clinicians providing a description of the mode of action and management of therapy for anticoagulant drugs used in everyday clinical practice in different clinical settings, including direct oral anticoagulants dabigatran, rivaroxaban, apixaban and edoxaban.

Cancer-Associated Thrombosis

Author : Alok A. Khorana
Publisher : CRC Press
ISBN 13 : 1420048007
Total Pages : 290 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Cancer-Associated Thrombosis by : Alok A. Khorana

Download or read book Cancer-Associated Thrombosis written by Alok A. Khorana and published by CRC Press. This book was released on 2007-09-26 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides

Guidelines for Antithrombotic Therapy

Author : Hirsh
Publisher : PMPH-USA
ISBN 13 : 9781550092660
Total Pages : 132 pages
Book Rating : 4.0/5 (926 download)

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Book Synopsis Guidelines for Antithrombotic Therapy by : Hirsh

Download or read book Guidelines for Antithrombotic Therapy written by Hirsh and published by PMPH-USA. This book was released on 2004 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thrombosis can be prevented and treated effectively by a variety of pharmacologic agents. This monograph provides a summary of the 2003 American College of Chest Surgeons Recommendations for pharmacologic agents, together with a brief review of the background data on which the therapeutic recommendations are based.

Antithrombotic Therapy

Author : Richard C. Becker
Publisher : Professional Communications
ISBN 13 : 1932610634
Total Pages : 466 pages
Book Rating : 4.9/5 (326 download)

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Book Synopsis Antithrombotic Therapy by : Richard C. Becker

Download or read book Antithrombotic Therapy written by Richard C. Becker and published by Professional Communications. This book was released on 2010-12-31 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical application of antithrombotic therapy in both arterial disease (acute coronary syndromes, acute MI, peripheral arterial disease, valvular heart disease, atrial fibrillation) and venous disease, (venous thromboembolic disease and pulmonary embolism). Results of major clinical trials and their implications for clinical practice.

New Therapeutic Agents In Thrombosis And Thrombolysis, Revised And Expanded, Second Edition

Author : Arthur Sasahara
Publisher : CRC Press
ISBN 13 : 9780824707958
Total Pages : 720 pages
Book Rating : 4.7/5 (79 download)

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Book Synopsis New Therapeutic Agents In Thrombosis And Thrombolysis, Revised And Expanded, Second Edition by : Arthur Sasahara

Download or read book New Therapeutic Agents In Thrombosis And Thrombolysis, Revised And Expanded, Second Edition written by Arthur Sasahara and published by CRC Press. This book was released on 2002-10-18 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents new chapters discussing the latest research on low-molecular-weight heparins, as well as agents such as pentasaccharide, TFP1, soluble thrombomodulin, and alfimeprase. Completely revised and expanded throughout, New Therapeutic Agents in Thrombosis and Thrombolysis details strategies to target conventional and recently characterized pathways of hemostasis minimize the prothrombotic function of activated platelets assess the biochemical and pharmacological effects of antithrombotic agents and discusses the use of animal models for determination of antithrombotic drug efficacy antithrombotic therapy as a key component of cardiovascular disease management the management of thromboembolic events in children and pregnant women Supplemented with more than 2000 contemporary references, New Therapeutic Agents in Thrombosis and Thrombolysis is an authoritative source for cardiologists, internists, primary care physicians, vascular medicine specialists, cardiovascular and vascular surgeons, hematologists, pulmonologists, critical care physicians, pharmacologists, pharmaceutical researchers, and fellows, residents, and graduate and medical school students in these disciplines.

Hepatotoxicity

Author : Hyman J. Zimmerman
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781719520
Total Pages : 848 pages
Book Rating : 4.7/5 (195 download)

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Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman

Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Guidelines of Antithrombotic Therapy

Author : Jack Hirsh
Publisher : B. C. Decker
ISBN 13 : 9781550091564
Total Pages : 76 pages
Book Rating : 4.0/5 (915 download)

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Book Synopsis Guidelines of Antithrombotic Therapy by : Jack Hirsh

Download or read book Guidelines of Antithrombotic Therapy written by Jack Hirsh and published by B. C. Decker. This book was released on 2001 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thrombosis, an important complication of atherosclerosis and of other various medical and surgical conditions, can be prevented and treated effectively by a variety of pharmacologic agents.The American College of Chest Physicians (ACCP) published proceedings of their first consen sus conference on antithrombotic therapy in 1986. In the last fourteen years, there has been enormous growth in the field, due to the develo pment of new and more powerful pharmacologic agents. This monograph pr ovides a summary of the 2000 ACCP recommendations for pharmacologic ag ents, together with a brief review of the background data on which the therapeutic recommendations are based.

Management of Acute Pulmonary Embolism

Author : Stavros V. Konstantinides
Publisher : Springer Science & Business Media
ISBN 13 : 1597452874
Total Pages : 273 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Management of Acute Pulmonary Embolism by : Stavros V. Konstantinides

Download or read book Management of Acute Pulmonary Embolism written by Stavros V. Konstantinides and published by Springer Science & Business Media. This book was released on 2007-12-31 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical volume highlights traditional, novel, and evolving aspects of the diagnosis and treatment of pulmonary embolism (PE). The contributors comprise an international team of experts. Important aspects of diagnosis, risk stratification, and differential treatment of patients with PE are presented in a concise, yet comprehensive manner. Emphasis is placed on specific issues related to PE, including pregnancy, cancer, thrombophilia, and air travel.

Antiplatelet Drugs in a Rat Microsurgical Model of Arterial Thrombosis

Author : Margaret Louise Bream
Publisher :
ISBN 13 :
Total Pages : 266 pages
Book Rating : 4.:/5 (17 download)

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Book Synopsis Antiplatelet Drugs in a Rat Microsurgical Model of Arterial Thrombosis by : Margaret Louise Bream

Download or read book Antiplatelet Drugs in a Rat Microsurgical Model of Arterial Thrombosis written by Margaret Louise Bream and published by . This book was released on 1978 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Anesthetic Pharmacology

Author : Alex S. Evers
Publisher : Cambridge University Press
ISBN 13 : 1139497022
Total Pages : 2902 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Anesthetic Pharmacology by : Alex S. Evers

Download or read book Anesthetic Pharmacology written by Alex S. Evers and published by Cambridge University Press. This book was released on 2011-03-10 with total page 2902 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Drug Discovery and Evaluation: Pharmacological Assays

Author : Hans Vogel
Publisher : Springer Science & Business Media
ISBN 13 : 3540714200
Total Pages : 2118 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Drug Discovery and Evaluation: Pharmacological Assays by : Hans Vogel

Download or read book Drug Discovery and Evaluation: Pharmacological Assays written by Hans Vogel and published by Springer Science & Business Media. This book was released on 2007-10-30 with total page 2118 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this successful reference offers both cutting-edge and classic pharmacological methods. Thoroughly revised and expanded to two volumes, it offers an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Every chapter has been updated, and numerous assays have been added. Each of the more than 1,000 assays comprises a detailed protocol outlining purpose and rationale, and a critical assessment of the results and their pharmacological and clinical relevance.

Heparin - A Century of Progress

Author : Rebecca Lever
Publisher : Springer Science & Business Media
ISBN 13 : 3642230563
Total Pages : 457 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Heparin - A Century of Progress by : Rebecca Lever

Download or read book Heparin - A Century of Progress written by Rebecca Lever and published by Springer Science & Business Media. This book was released on 2012-05-08 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.

Drug Discovery and Evaluation

Author : H. Gerhard Vogel
Publisher : Springer Science & Business Media
ISBN 13 : 3540256385
Total Pages : 896 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Drug Discovery and Evaluation by : H. Gerhard Vogel

Download or read book Drug Discovery and Evaluation written by H. Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2006 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a landmark in the continuously changing world of drugs. It is essential reading for scientists and managers in the pharmaceutical industry who are involved in drug finding, drug development and decision making in the development process.

Omega Fatty Acids in Brain and Neurological Health

Author : Ronald Ross Watson
Publisher : Academic Press
ISBN 13 : 0128152397
Total Pages : 520 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Omega Fatty Acids in Brain and Neurological Health by : Ronald Ross Watson

Download or read book Omega Fatty Acids in Brain and Neurological Health written by Ronald Ross Watson and published by Academic Press. This book was released on 2019-06-12 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrates the importance of omega-3 fatty acids in longevity, cognitive impairment and structure and function of the brain's neurons and also the adverse effects of omega-6 fatty acids on neurological function. This book encompasses some of the most recent research on the links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep and neurodegenerative diseases. This completely updated second edition focuses on the counterbalancing dietary and tissue omega-6 fatty acids as well as it studies the effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases. - Provides a comprehensive introduction to omega-3 and omega-6 fatty acids in neurological health and directions for future research - Features novel focus on the adverse effects of omega-6 fatty acids on neurological function and the counterbalancing of dietary and tissue omega-6 - Illustrates the importance of omega-3 fatty acids in longevity and cognitive impairment - Features new chapters on early effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases - Discusses links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements

Anticoagulants, Antiplatelets, and Thrombolytics

Author : Shaker A. Mousa
Publisher : Humana
ISBN 13 :
Total Pages : 340 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Anticoagulants, Antiplatelets, and Thrombolytics by : Shaker A. Mousa

Download or read book Anticoagulants, Antiplatelets, and Thrombolytics written by Shaker A. Mousa and published by Humana. This book was released on 2010-08-17 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decade, remarkable progress has been made in the development of newer drugs to prevent and treat thromboembolic disorders, such as oral direct anti-Xa and anti-IIa antagonists, as well as oral antiplatelet ADP antagonists with rapid onset and offset. In addition, there has been concentrated effort aimed at identifying novel uses of traditional antithrombotic drugs, such as aspirin, heparin, and oral anticoagulants, as well as combinations of agents, such as more than one antiplatelet, antiplatelet with anticoagulant, antiplatelet with or without thrombolytic. Anticoagulants, Antiplatelets, and Thrombolytics, Second Edition provides updates on various strategies in thrombosis, experimental models, and clinical and recent advances in the discovery and development of novel antithrombotics. As a volume in the highly successful Methods in Molecular BiologyTM series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Easy to use and up to date, Anticoagulants, Antiplatelets, and Thrombolytics, Second Edition is an ideal guide for researchers aiming for the future of this vital field, focusing on the prevention of thromboembolic disorders and the protection of the vascular endothelium.