Antirheumatic Therapy Actions And Outcomes

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Antirheumatic Therapy: Actions and Outcomes

Author : Richard O. Day
Publisher : Springer Science & Business Media
ISBN 13 : 3764377267
Total Pages : 350 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Antirheumatic Therapy: Actions and Outcomes by : Richard O. Day

Download or read book Antirheumatic Therapy: Actions and Outcomes written by Richard O. Day and published by Springer Science & Business Media. This book was released on 2010-05-30 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our goal for this book is to examine the contemporary therapy of rheumatoid arthritis (RA) from the increasingly important perspective of impact upon quality of life, costs and long-term health outcomes. For too long the focus has been on short term, symptomatic, and surrogate indicator outcomes. Yet RA is a life-long disor der with the majority of impact on an individual patient many years following onset. Further, even in the short-term, researchers and rheumatologists have tended to emphasize measurements of disease activity such as joint counts, ESR and physi cian's opinion as to the amount of disease activity present. It is only relatively recently that measures of structural damage, quality of life and impact on broad domains of health have been given increasing emphasis. Also, the significance of early treatment of RA in order to optimise long-term outcomes has a relatively short history [1]. We have been focussed on the disease processes as surrogates for long term outcomes. Until the short-term process measures are validated as surrogates of long-term effects we should also turn our attention to outcomes of disease and the impact of our management on those outcomes [2). Inour view, this book is especially timely. We are at the dawn of a revolution in the management of RA and other complex immunological inflammatory disorders because their molecular, genetic and environmental mechanisms are being unrav elled. Inthe process, we are revealing a substantial number of novel and significant targets for pharmacotherapy.

New Developments in Antirheumatic Therapy

Author : K. D. Rainsford
Publisher : Springer Science & Business Media
ISBN 13 : 9400912536
Total Pages : 331 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis New Developments in Antirheumatic Therapy by : K. D. Rainsford

Download or read book New Developments in Antirheumatic Therapy written by K. D. Rainsford and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: At present we may be at the cross-roads in the therapeutic approaches we have for the treatment of the 100 or more rheumatic conditions. This is be cause we now recognise that although some advances have been made with the development of a large range of non-steroidal and steroidal drugs during the past two decades or so, we now recognise that many, if not all, of these have rather limited effects on many of the disease processes which underlie the manifestations of the various rheumatic states. Advances in molecular bi- 010gy in the past 5-10 years have enabled these tools to be applied extensive ly for developing further our understanding of the rheumatic disease processes. In some cases these molecular tools (e. g. ,),-interferon, interleukin- 2, T-cell antibodies) have been directly employed as therapies themselves. While the outcome from trials with such agents in rheumatoid arthritis in particular has not been as would have been hoped, these results as with cy closporin A and low-dose methotrexate in the therapy of rheumatoid arth ritis have given us important indications for the approach employing what are generally described as "immunomodulators" to control this disease. But this may not be the same type of approach which is desirable for all types of rheumatic conditions. Indeed, even the way which the present range of drugs and other therapies are applied may not be the most effective and safe means of treating different types of arthritic conditions.

Davis's Drug Guide for Rehabilitation Professionals

Author : Charles D. Ciccone
Publisher : F.A. Davis
ISBN 13 : 0803640048
Total Pages : 1217 pages
Book Rating : 4.8/5 (36 download)

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Book Synopsis Davis's Drug Guide for Rehabilitation Professionals by : Charles D. Ciccone

Download or read book Davis's Drug Guide for Rehabilitation Professionals written by Charles D. Ciccone and published by F.A. Davis. This book was released on 2013-03-21 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition!

Skills in Rheumatology

Author : Hani Almoallim
Publisher : Springer Nature
ISBN 13 : 9811583234
Total Pages : 562 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Skills in Rheumatology by : Hani Almoallim

Download or read book Skills in Rheumatology written by Hani Almoallim and published by Springer Nature. This book was released on 2021-01-05 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access book presents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance ofdetailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd). Featuring easy-to-understand flow diagrams and explaining the common medical problems associated with rheumatic disease, such as shortness of breath and anemia, it is not only a valuable resource to rheumatologists, but will also appeal to medical students, junior residents, and primary healthcare physicians.

Early Rheumatoid Arthritis

Author : Paul Emery
Publisher :
ISBN 13 : 9781416027676
Total Pages : 0 pages
Book Rating : 4.0/5 (276 download)

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Book Synopsis Early Rheumatoid Arthritis by : Paul Emery

Download or read book Early Rheumatoid Arthritis written by Paul Emery and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue covers the latest developments in the understanding of rheumatoid arthritis at the early stage. Treatments such as with newer biologic agents and conventional disease-modifying antirheumatic drugs are reviewed. Also included are articles on imaging modalities as a means of identifying those in the early stages and monitoring response to treatment.

Selected Health Conditions and Likelihood of Improvement with Treatment

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309670950
Total Pages : 319 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Selected Health Conditions and Likelihood of Improvement with Treatment by : National Academies of Sciences, Engineering, and Medicine

Download or read book Selected Health Conditions and Likelihood of Improvement with Treatment written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-07-12 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Social Security Administration (SSA) administers two programs that provide disability benefits: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. SSDI provides disability benefits to people (under the full retirement age) who are no longer able to work because of a disabling medical condition. SSI provides income assistance for disabled, blind, and aged people who have limited income and resources regardless of their prior participation in the labor force. Both programs share a common disability determination process administered by SSA and state agencies as well as a common definition of disability for adults: "the inability to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than 12 months." Disabled workers might receive either SSDI benefits or SSI payments, or both, depending on their recent work history and current income and assets. Disabled workers might also receive benefits from other public programs such as workers' compensation, which insures against work-related illness or injuries occurring on the job, but those other programs have their own definitions and eligibility criteria. Selected Health Conditions and Likelihood of Improvement with Treatment identifies and defines the professionally accepted, standard measurements of outcomes improvement for medical conditions. This report also identifies specific, long-lasting medical conditions for adults in the categories of mental health disorders, cancers, and musculoskeletal disorders. Specifically, these conditions are disabling for a length of time, but typically don't result in permanently disabling limitations; are responsive to treatment; and after a specific length of time of treatment, improve to the point at which the conditions are no longer disabling.

Drug-Induced Liver Injury

Author :
Publisher : Academic Press
ISBN 13 : 0128173173
Total Pages : 288 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug-Induced Liver Injury by :

Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Introduction to Basics of Pharmacology and Toxicology

Author : Abialbon Paul
Publisher : Springer Nature
ISBN 13 : 9813360097
Total Pages : 1156 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Introduction to Basics of Pharmacology and Toxicology by : Abialbon Paul

Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Oxford Desk Reference

Author : Richard Watts
Publisher :
ISBN 13 : 0199229996
Total Pages : 613 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis Oxford Desk Reference by : Richard Watts

Download or read book Oxford Desk Reference written by Richard Watts and published by . This book was released on 2009 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rheumatology is an ever-changing specialty in which the amount of available information is growing daily and spread across a myriad of books, journals and websites. The Oxford Desk Reference: Rheumatology brings this information together in an easy-to-use format. This essential resource combines up-to-date, relevant, evidence-based information with the latest guidelines and the experience of senior consultants. The book is designed such that each subject forms a self-contained topic in its own right, laid out across two or four pages to facilitate the key aim of rapid and easy access to information. This makes the information included simple to find, read and absorb, so that the book can be consulted in the clinic or ward setting for information on the optimum management of a particular condition. Written by internationally renowned rheumatology consultants, with expert contributors for each section, this book is must-have resource for all rheumatologists and an excellent reference for all doctors.

Mosaic of Autoimmunity

Author : Carlo Perricone
Publisher : Academic Press
ISBN 13 : 012814307X
Total Pages : 728 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Mosaic of Autoimmunity by : Carlo Perricone

Download or read book Mosaic of Autoimmunity written by Carlo Perricone and published by Academic Press. This book was released on 2019-02-15 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis. Highlights the concept of the mosaic of autoimmune manifestations Includes new visions on unsuspected molecules Provides updated knowledge to physicians helping patients with autoimmune diseases Presents thorough, up-to-date information on specific diseases, along with clinical applications

Oxford Textbook of Rheumatology

Author : Philip Conaghan
Publisher : Oxford University Press
ISBN 13 : 0199642486
Total Pages : 1553 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Oxford Textbook of Rheumatology by : Philip Conaghan

Download or read book Oxford Textbook of Rheumatology written by Philip Conaghan and published by Oxford University Press. This book was released on 2013-10 with total page 1553 pages. Available in PDF, EPUB and Kindle. Book excerpt: A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.

Pain Management Secrets E-Book

Author : Charles E. Argoff
Publisher : Elsevier Health Sciences
ISBN 13 : 0323074650
Total Pages : 408 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Pain Management Secrets E-Book by : Charles E. Argoff

Download or read book Pain Management Secrets E-Book written by Charles E. Argoff and published by Elsevier Health Sciences. This book was released on 2009-07-31 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: No matter what questions arise in practice or while preparing for boards, Pain Management Secrets, 3rd Edition has the answers. A two-color page layout, portable size, and a list of the “Top 100 Secrets in pain management help you better meet the challenges you face today. You’ll find all the features you rely on from the Secrets Series®—a question-and-answer format, lists, mnemonics, tables and an informal tone—that make reference fast and easy. Expedites reference and review with a question-and-answer format, bulleted lists, mnemonics, and practical tips from the authors. Features a two-color page layout, "Key Points" boxes, and lists of useful web sites to enhance your reference power. Presents a chapter containing "Top 100 Secrets", providing you with an overview of essential material for last-minute study or self-assessment. Fits comfortably in the pocket of your lab coat so you have it conveniently on hand at all times. Features new editors, Charles E. Argoff, MD and Gary McCleane, MD who present a thorough update on the latest in pain management. Presents a new contemporary internal design that helps you navigate the text easier.

Regulatory T Cells in Inflammation

Author : Arne N. Akbar
Publisher : Springer Science & Business Media
ISBN 13 : 9783764370886
Total Pages : 260 pages
Book Rating : 4.3/5 (78 download)

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Book Synopsis Regulatory T Cells in Inflammation by : Arne N. Akbar

Download or read book Regulatory T Cells in Inflammation written by Arne N. Akbar and published by Springer Science & Business Media. This book was released on 2005-03-22 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific interest in regulatory T cells has revived during the last decade. Initially described in the early seventies as suppressor T cells, the concept of suppressor/regulatory T cells went through turbulent times during the eighties when molecular analysis failed to identify putative suppressor genes. The constructive and elegant cellular experiments on regulatory T cells during the nineties, initiated by Shimon Sakaguchi and co-workers, however have brought these cells back into the limelight. Nowadays, regulatory T cells are regarded as essential components of the immune system, and several different subsets of regulatory T cells have been described. Considerable regulatory function has been attributed to the CD4+CD25+ T cell subset. These cells act by suppressing adaptive and possibly also innate immune responses thereby maintaining or restoring the balance between immunity and tolerance. The suppressive effects of CD4+CD25+ regulatory T cells are cell-contact dependent but a role for soluble factors, particularly in vivo, has been suggested as well. The aim of this book is to bring together recent developments and viewpoints in the field of CD4+CD25+ regulatory T cells and to discuss the potential use of regulatory T cells in immunotherapy of inflammatory diseases. By linking data on regulatory T cells from experimental models with recent findings from the clinic, this topical book will be of interest to immunologists and other biomedical researchers as well as clinicians that are interested in regulation and manipulation of the immune response during (chronic) inflammatory disease.

Principles of Immunopharmacology

Author : Frans P. Nijkamp
Publisher : Springer Science & Business Media
ISBN 13 : 376437408X
Total Pages : 659 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Principles of Immunopharmacology by : Frans P. Nijkamp

Download or read book Principles of Immunopharmacology written by Frans P. Nijkamp and published by Springer Science & Business Media. This book was released on 2006-04-04 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid developments in immunology in recent immunomodulatory drugs can be distinguished years have dramatically expanded our knowledge of from their beneficial therapeutic effects. mammalian host defence mechanisms. The molecu- Currently,it is only possible to obtain an overview lar mechanisms of cellular interactions during of these various aspects of immunopharmacology immune responses have been unravelled,the intra- by reading a range of immunological,pharmacol- cellular responses involved in signal transduction ical,diagnostic and toxicological literature. Good delineated and an ever-increasing number of soluble immunological textbooks are available, while mediators of immune and inflammatory reponses immunopharmacology is covered mainly in terms of have been discovered. the inflammatory response. Principles of Immuno- The initial result of this explosion of knowledge pharmacology is intended to provide for the first time has been to provide the researcher and the clinician in a single volume a basic understanding of with an arsenal of diagnostic tools with which the immunological mechanisms,a review of important immunological bases of disease processes can be immunodiagnostic tools and a description of the investigated. This has made disease diagnosis much main pharmacological agents which modify the more precise,enabling the physician to tailor therapy immune response,together with an introduction to much more closely to the individual patient’s needs. immunotoxicology. As such we hope that it will be However,better understanding of disease processes useful as a reference text for physicians,researchers only provides a gradual improvement in therapy. This and students with a rudimentary knowledge of is because the new molecular targets that have been immunology.

Encyclopedia of Inflammatory Diseases

Author :
Publisher : Birkhäuser
ISBN 13 : 9783764385309
Total Pages : 0 pages
Book Rating : 4.3/5 (853 download)

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Book Synopsis Encyclopedia of Inflammatory Diseases by :

Download or read book Encyclopedia of Inflammatory Diseases written by and published by Birkhäuser. This book was released on 2016-09-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation has become one of the most exciting and rewarding areas of medical research. Recent years have seen a revolution in our understanding of how blood and tissue cells interact and of the intracellular mechanisms controlling their activation. This has revealed the underlying inflammatory pathology of many diseases and provided multiple new targets for anti-inflammatory and immunomodulatory therapy. The Encyclopedia of Inflammatory Diseases will cover the following areas: Inflammatory Processes and Cells Inflammatory Diseases Mediators of Inflammation Pharmacology of Inflammation Since inflammatory diseases and their therapy cover a broad range of scientific and medical fields, the encyclopedia will be co-edited by four international experts, a clinician and three researchers from the disciplines of immunology, biochemistry, and pharmacology, in this way providing students, basic and clinical scientists and practitioners in academia, hospitals and industry with valuable interlinked information. This living project will serve as a reliable and comprehensive data pool for everybody working in inflammation research. Owing to its dynamic nature, it will grow with time and future editions, becoming an indispensible source of information for academia, clinical practitioners and industry.

Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases

Author : Ronald Ross Watson
Publisher : Academic Press
ISBN 13 : 0128138211
Total Pages : 628 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases by : Ronald Ross Watson

Download or read book Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases written by Ronald Ross Watson and published by Academic Press. This book was released on 2019-01-26 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive Food as Dietary Interventions for Arthritis and Inflammatory Diseases, Second Edition is a valuable scientific resource that focuses on the latest advances in bioactive food research and the potential benefit of bioactive food choice on arthritis. Written by experts from around the world, the book presents important information that can help improve the health of those at risk for arthritis and related conditions using food selection as its foundation. Serves as a starting point for in-depth discussions in academic settings Offers detailed, well-documented reviews outlining the ability of bioactive foods to improve and treat arthritis Includes updated research on the global epidemic of diabetes Updated with current research on antioxidant flavonoids, anti-Inflammatory natural foods, ginger and the effects of beef on inflammation Documents foods that can affect metabolic syndrome and ways the associated information could be used to understand other diseases that share common etiological pathways

A Clinician's Pearls & Myths in Rheumatology

Author : John H. Stone
Publisher : Springer Science & Business Media
ISBN 13 : 1848009348
Total Pages : 489 pages
Book Rating : 4.8/5 (48 download)

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Book Synopsis A Clinician's Pearls & Myths in Rheumatology by : John H. Stone

Download or read book A Clinician's Pearls & Myths in Rheumatology written by John H. Stone and published by Springer Science & Business Media. This book was released on 2009-10-03 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Important strides have been made in understanding the pathophysiologic basis of many inflammatory conditions in recent years, but rheumatology remains a discipline in which diagnosis is rooted in the medical history skillfully extracted from the patient, the careful physical examination, and the discriminating use of laboratory tests and imaging. Moreover, selection of the most appropriate therapy for patients with rheumatic diseases also remains heavily reliant upon clinical experience. Medical disciplines such as rheumatology that depend significantly upon clinical wisdom are prone to the development of systems of ‘Pearls’ and ‘Myths,’ related to the diseases they call their own, a ‘Pearl’ being a nugget of truth about the diagnosis or treatment of a particular disease that has been gained by dint of clinical experience and a ‘Myth’ being a commonly held belief that influences the practice of many clinicians – but is false. This book will pool together the clinical wisdom of seasoned, expert rheumatologists who participate in the care of patients with autoimmune diseases, systemic inflammatory disorders, and all other rheumatic conditions.