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Antioxidant Antidiabetic Agents And Human Health
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Book Synopsis Antioxidant-Antidiabetic Agents and Human Health by : Oluwafemi Oguntibeju
Download or read book Antioxidant-Antidiabetic Agents and Human Health written by Oluwafemi Oguntibeju and published by BoD – Books on Demand. This book was released on 2014-02-05 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human system employs the use of endogenous enzymatic as well as non-enzymatic antioxidant defence systems against the onslaught of free radicals and oxidative stress. Enzymatic antioxidants and non-enzymatic antioxidants work synergistically with each other, using different mechanisms against different free radicals and stages of oxidative stress. Dietary and lifestyle modifications are seen as the mainstay of treatment and management of chronic diseases such as diabetes mellitus. The major aims of dietary and lifestyle changes are to reduce weight, improve glycaemic control and reduce the risk of coronary heart disease, which accounts for 70- 80% of deaths among those with diabetes. It is also important to note that medicinal plants have been used as medicines since ancient time, and continue to play significant role even in modern medicine in management and treatment of chronic diseases. Impressive numbers of modern therapeutic agents have been developed from plants. Phytochemicals have been isolated and characterised from fruits such as grapes and apples, vegetables such as broccoli and onion, spices such as turmeric, beverages such as green tea and red wine, as well as many other sources. The WHO estimates that approximately 80% of the worlds inhabitants rely on traditional medicine for their primary health care and many medicinal plants have ethno-medical claims of usefulness in the treatment of diabetes and other chronic diseases globally, and have been employed empirically in antidiabetic, antihyperlipidemic, antihypertensive, antinflammatory and antiparasitic remedies. This book examines the role of antioxidant-rich natural products in management and treatment of diabetes and other chronic diseases.
Book Synopsis Diabetes Mellitus and Human Health Care by : Anne George
Download or read book Diabetes Mellitus and Human Health Care written by Anne George and published by CRC Press. This book was released on 2016-04-19 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will enlighten on some of the recent progress in diabetic care and therapy. Diabetes mellitus is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because of the inability of cells to respond to the insulin that is produced. According to the recent report of World Health Organization, 346 million people worldwide are suffering from diabetes, and in 2004, approximately 3.4 million people died as a result of high blood sugar. This book explores applying both classical and modern approaches to the management of diabetes by focusing on a holistic approach. Great attention has been focused on global trends in diabetes, epidemiology of diabetes, inhibitors in diabetes and diabetes therapy, vitamins and diabetes, and the role of dietary fats in diabetes in this book. Topics include: • diabetic foot ulcers and therapeutic footwear • Withania coagulans. Dunal as an antidiabetic herb • the pharmacological interventions for diabetic cardiomyopathy • the use of saliva as a noninvasive tool to monitor glycemic control in diabetic patients • a cutting-edge biomedical device for continuous in vivo glucose monitoring • the temporal effect of repeated stress in the pathophysiology of T2DM • nanosensor technology for glucose detection The editors and authors emphasize a holistic approach toward the diagnosis, treatment, and management of diabetes by joining hands with experts from various disciplines Medical students and doctors of modern medicine, Ayurveda, homeopathy, etc., medical reserachers, researchers in the area of diabetes, pharma professionals.
Book Synopsis Oxidative Stress by : Silvana Andreescu
Download or read book Oxidative Stress written by Silvana Andreescu and published by ACS Symposium. This book was released on 2016-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the oxidative stress related mechanisms in biological systems and the involvement of reactive oxygen and nitrogen species (ROS and RNS), the damage of DNA, proteins, and lipids caused by oxidative stress, the protection of cells and tissues against free radicals, the relation of the oxidative stress to aging and human diseases including cancer and neurological disorders, and the development of new therapeutic approaches to modulate oxidative stress. The current state-of-the-art methodologies including the development of sensors and biosensors for the detection of ROS/RNS and of biomarkers of oxidative stress are also discussed. The book is organized in three overlapping parts, starting with general considerations of the oxidative stress, homeostasis pathways, and ROS mechanisms, followed by chapters discussing the involvement of ROS in particular diseases and concluding with analytical aspects of oxidative stress monitoring. The book provides a solid background on oxidative stress and ROS/RNS generation for novice learners while also offering scientists and practitioners already involved in this field a wealth of information covering the most recent developments in the study of oxidative stress, the role of radical species, novel antioxidant therapies, and methods for assessing free radicals and oxidative stress.
Book Synopsis Plant Antioxidants and Health by : Halina Maria Ekiert
Download or read book Plant Antioxidants and Health written by Halina Maria Ekiert and published by Springer. This book was released on 2022-06-26 with total page 861 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive reference guide to plant-derived antioxidants, their beneficial effects, mechanisms of action, and role in disease prevention and improving general health (anti-ageing effect). The content is divided into three main parts, the first of which covers various antioxidants (such as polyphenols, carotenoids, tocopherols, tocotrienols, glutathione, ascorbic acid), their origins, plant biochemistry and industrial utilization. In turn, the book’s second, main part focuses on antioxidants’ beneficial health effects, explains biochemical fundamentals such as the free radical theory and oxidative stress, and discusses antioxidants’ role in e.g. cancer, cardiovascular diseases, inflammation, degenerative diseases and ageing. The third part reviews general laboratory methods for antioxidant screening, preservation and determination. Written by an international team of experts, this highly interdisciplinary book will benefit a broad range of health professionals and researchers working in biochemistry, biotechnology, nutrition, plant science and food chemistry. It offers an indispensable, up-to-date guide for anyone interested in antioxidants and the role of a plant-based diet in disease prevention and control
Download or read book Resveratrol written by Farid A. Badria and published by BoD – Books on Demand. This book was released on 2019-02-06 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book intends to strike a balance between developments in research and the fact that researchers must absorb and link to scientific advances with clinical practice so that the management of diseases can be based on sound physiological concepts. This book addresses several controversial issues regarding a natural molecule with fascinating pharmacological and therapeutic effects. The book contains three sections: Section 1: Pharmacology and Therapeutic Applications of Resveratrol; Section 2: Bioavailability, Metabolism, and Mode of Action of Resveratrol; Section 3: Resveratrol and Its Role in Chronic and Degenerative Diseases. Does it Add Life to Years or Years to Life? It is our hope that this book will motivate readers to approach the evidence on the use resveratrol and thereby spark an interest in making further contributions to the current scientific debate and treatment development efforts.
Book Synopsis Plant-derived Bioactives by : Mallappa Kumara Swamy
Download or read book Plant-derived Bioactives written by Mallappa Kumara Swamy and published by Springer Nature. This book was released on 2020-05-11 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs.
Book Synopsis Anthocyanins: Antioxidant Properties, Sources and Health Benefits by : José Manuel Lorenzo
Download or read book Anthocyanins: Antioxidant Properties, Sources and Health Benefits written by José Manuel Lorenzo and published by . This book was released on 2020 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anthocyanins are compounds associated with multiple interesting effects and potential applications. This group of natural compounds can be found in many foods (ranging from red to blue depending on the matrix) such as berries, eggplant, plums, black beans and red grapes. Moreover, the knowledge accumulated so far support the key role of anthocyanins in food and pharmaceutical industry, research and in the life of consumers. The versatility of effects attributed to anthocyanins is disclosed in this book by covering several aspects ranging from its chemical and physical characteristics, separation and identification, techniques to preserve isolated compounds and reaching the healthy benefits and its use in sports.In Chapter 1, the fundaments and main aspects related to anthocyanins are disclosed. The scientific evidence indicates positive effects were related to anticancer, antioxidant, antidiabetic and inflammatory effects, for instance. In addition, anthocyanins are excellent food additives by improving the color of food in the range between red and blue. Moreover, the applications are also related to strategies to extract and improve the stability of isolated compounds. A successful isolation is necessary to obtain anthocyanins for pharmaceutical and food applications. Chapter 2 aimed to explore the concepts and advances made to improve the recovery of anthocyanins from several types of sources. It also explored the characteristics of both conventional and novel technologies.The isolation of anthocyanins also requires an adequate approach to identify and quantify each compound within this class. Chapter 3 is dedicated to discuss the approaches to identify and quantify anthocyanins, particularly for mass spectroscopic, nuclear magnetic resonance and high performance liquid chromatography. In addition, the aspects related to method validation are also explored. Once the extraction and adequate quantification of isolated anthocyanins occurs, it is of great value to prevent their degradation. The concepts and use of encapsulation technique are discussed in Chapter 4. Particular attention is given to the methods and the composition of encapsulating material to improve stability.Prior to considering the biological effect and health benefits associated with the consumption of anthocyanins, the consumption and crucial events during the digestion and absorption must be considered in order to clarify and support strategies in food and pharmaceutical applications. The concepts, biological events (with emphasis on digestion) and the role of gut microbiota on the bioaccessibility and bioavailability of anthocyanins are presented in Chapter 5. Following the absorption of anthocyanins several biological effects related to health benefits were reported in scientific literature. The first and preserve knowledge is related to the traditional consumption in order to treat diseases in folk medicine. This perspective and the scientific evidence raised so far are compiled in Chapter 6. In the chapter, the different plants sources to treat diseases are described.In Chapter 7, the relation between anthocyanins and antioxidant activity is discussed. The chapter contains the fundaments and scientific data regarding oxidative stress, lipid oxidation and evaluation of antioxidant activity (in both in vivo and in vitro methods). Moreover, the data from purified compounds and natural extracts are also presented and discussed. Another relevant benefit associated with anthocyanins is their impact on cardiovascular diseases. Chapter 8 presents the main factors associated with the development of cardiovascular diseases and discussed the role of anthocyanins to prevent the progression of this disease. Particular attention is given to the dietary sources of anthocyanins.Reducing the burden of cancer is another pertinent effect related to anthocyanins. In order to disclose the impact of anthocyanins against the development of cancer, Chapter 9 compiles fundamental concepts and scientific data supporting their role against this disease. Particular attention is given to pharmacokinetic of anthocyanins. Additionally, the development of food products for cancer survivors was also included in this chapter.Diabetes is a major disease that imposes limitation in the life of their carriers. Anthocyanins are important dietary components that can induce meaningful effects, at in vitro and in vivo level, to reduce the impact of diabetes in health. This perspective and the scientific data supporting it are discussed in Chapter 10. The inflammatory process is a major response mechanism in the human body. Once this process is dysregulated, a major impairing in health can occur. In Chapter 11, the mechanism by which anthocyanins act as anti-inflammatory compounds on affect key molecules and pathways are described.Neurodegenerative diseases, particularly during aging, are a major concern due to severe limitations related to memory and motion. Chapter 12 is dedicated to disclose the role and mechanisms related to neurodegenerative diseases. Additionally, this chapter also presents the concepts and scientific data regarding the brain bioavailability of anthocyanins. The benefits associated with anthocyanins are not limited to reduce the risk associated with diseases, these compounds are also relevant dietary supplements for athletes. The role on the reduction of oxidative stress and in the performance of athletes and physically active people is discussed in Chapter 13.
Book Synopsis Polyphenols in Human Health and Disease by : Ronald Ross Watson
Download or read book Polyphenols in Human Health and Disease written by Ronald Ross Watson and published by Academic Press. This book was released on 2013-10-26 with total page 1504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more. Explores neuronal protection by polyphenol metabolites and their application to medical care Defines modulation of enzyme actions to help researchers see and study polyphenols’ mechanisms of action, leading to clinical applications Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases
Book Synopsis Free Radicals: from Basic Science to Medicine by : POLI
Download or read book Free Radicals: from Basic Science to Medicine written by POLI and published by Birkhäuser. This book was released on 2013-03-11 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free radical-mediated reactions have been well known in chemistry and physical chemistry for many years. Applying this knowledge to living organisms, biochemists have shown that reactive free radicals are formed at many intracellular sites during normal metabolism, and they have started to suggest possible roles in various pathological processes and conditions, for example in radiation damage, in the metabolism of xenobiotics, in carcinogenesis and in metabolic disorders. At present, a large and relevant mass of experimental evidence supports the view that reactive free radicals are involved in the pathogenesis of several diseases and syndromes. This literature has captured the attention and interest of people involved in the biomedical field. Exciting developments in radical research are probable in the near future, establishing a greater interaction between basic science research and medicine. While the task of defining the involvement of free radicals in human pathology is difficult, it is nonetheless extremely important that such interaction be fulfilled as soon as possible. These were the considerations motivating us during the organization of the VI Biennial Meeting of the International Society for Free Radical Research held in Torino, Italy, in June 1992, and also during the preparation of this book. Experts in the various aspects of free radical research were invited to participate in the Torino Meeting and to contribute chapters for this volume.
Book Synopsis Antioxidants in Fruits: Properties and Health Benefits by : Gulzar Ahmad Nayik
Download or read book Antioxidants in Fruits: Properties and Health Benefits written by Gulzar Ahmad Nayik and published by Springer Nature. This book was released on 2020-12-15 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of the antioxidant value of widely consumed fruits. Each chapter covers the botanical description, nutritional & health properties of these popular fruits. Fruits are one of the most important indicators of dietary quality and offer protective effects against several chronic diseases such as cardiovascular diseases, obesity, and various types of cancer. In order to effectively promote fruit consumption, it is necessary to know and understand the components of fruits. In addition to underscoring the importance of fruit consumption’s effects on human diet, the book addresses the characterization of the chemical compounds that are responsible for the antioxidant proprieties of various fruits. Given its scope, the book will be of interest to graduate and post-graduate students, research scholars, academics, pomologists and agricultural scientists alike. Those working in various fruit processing industries and other horticultural departments will also find the comprehensive information relevant to their work.
Download or read book Flavonoids written by José Justino and published by BoD – Books on Demand. This book was released on 2017-08-23 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flavonoids are abundant secondary metabolites found in plants and fungi that have various roles in these organisms, including pigmentation, cell signalling, plant defence and inter-organism communication. Due to their abundance in nature, flavonoids are also important components of the human diet, and the last four decades have seen an intense study focused on the structure characterization of flavonoids and on their roles in mammal metabolism. This book reviews most of the well-established activities of flavonoids, and we also present more recent research studies on the area of flavonoids, including the chemical aspects of structure characterization of flavonoids, the biosynthesis of flavonoids in model plants as well as their role in abiotic stress situations and in agriculture, the role of flavonoids in metabolism and health and their importance in foods, from consumption to their use as bioactive components.
Book Synopsis Herbal Medicine by : Iris F. F. Benzie
Download or read book Herbal Medicine written by Iris F. F. Benzie and published by CRC Press. This book was released on 2011-03-28 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Book Synopsis The Wheatgrass Book by : Ann Wigmore
Download or read book The Wheatgrass Book written by Ann Wigmore and published by Penguin. This book was released on 1985-10-01 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Wheatgrass Book is written by Ann Wigmore - the woman who introduced wheatgrass juice to America 30 years ago. Ann's book contains a wealth of information on wheatgrass - from its nutrient properties to ways of easily growing it for the home juicer. Chapters include: green power from wheatgrass, how wheatgrass chlorophyll works, super nutrition from wheatgrass, how to grow and juice wheatgrass and the many uses of wheatgrass. This is a must for the person serious about incorporating wheatgrass into his or her health regimen.
Book Synopsis Asian Functional Foods by : John Shi
Download or read book Asian Functional Foods written by John Shi and published by CRC Press. This book was released on 2005-03-03 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: The consumption of functional foods has emerged as a major consumer-driven trend, based on the needs of an ever-growing health conscious population that wants to exercise greater control over its health. Focusing on an important sector of this rapidly growing field, Asian Functional Foods discusses the theoretical and practical aspects of functiona
Book Synopsis Anti-aging Drugs by : Alexander M Vaiserman
Download or read book Anti-aging Drugs written by Alexander M Vaiserman and published by Royal Society of Chemistry. This book was released on 2017-01-18 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.
Book Synopsis Bioactive Compounds of Medicinal Plants by : Megh R. Goyal
Download or read book Bioactive Compounds of Medicinal Plants written by Megh R. Goyal and published by CRC Press. This book was released on 2018-07-04 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume sheds new light on the immense potential of medicinal plants for human health from different technological aspects. It presents new research on bioactive compounds in medicinal plants that provide health benefits, including those that have proven especially effective in treating and managing diabetes mellitus and hypertension. It looks at the medicinal properties, antioxidant capacity, and antimicrobial activity of plants and provides scientific evidence on the use of medicinal plants in the treatment of certain diseases. Many of the plants described in the chapters are easily accessible and are believed to be effective with fewer side effects in comparison to modern drugs in the treatment of different diseases.
Book Synopsis Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 6 by : Atta-ur-Rahman
Download or read book Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 6 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2021-11-05 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research – Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research. The sixth volume of this series features 6 reviews which are informative guides to therapy and drug administration in diabetes and metabolic syndrome, for both the medical specialist and the pharmacologist. - The failing heart in diabetes with special emphasis on prevention - Flavonoids as prominent anti-diabetic agents - Chemosensor in glucose monitoring, advances and challenges - Synergistic drugs and polyherbal formulations for obesity: current status and future prospectives - Urge for herbal anti-diabetic medicines towards clinical and therapeutic implications - Curcuma longa as dietary supplement and diabetes mellitus: evidence from experimental studies
