Anticipatory Ethics And The Use Of Crispr In Humans

Download Anticipatory Ethics And The Use Of Crispr In Humans full books in PDF, epub, and Kindle. Read online Anticipatory Ethics And The Use Of Crispr In Humans ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Anticipatory Ethics and The Use of CRISPR in Humans

Author : Michael W. Nestor
Publisher : Springer Nature
ISBN 13 : 3030983684
Total Pages : 156 pages
Book Rating : 4.0/5 (39 download)

DOWNLOAD NOW!

Book Synopsis Anticipatory Ethics and The Use of CRISPR in Humans by : Michael W. Nestor

Download or read book Anticipatory Ethics and The Use of CRISPR in Humans written by Michael W. Nestor and published by Springer Nature. This book was released on 2022-05-20 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: The future of gene editing in humans will involve the use of CRISPR. How we think about the combination of the scientific, ethical, and moral aspects of this technology is paramount to the success or failure of CRISPR in humans. Unfortunately, the current scientific discussion around CRISPR in humans has left ethics trailing behind due to the rapid pace of innovation. New modes of ethics and stakeholder participation are needed to keep pace with rapid scientific advances and provide the necessary policy and ethical frameworks necessary to help CRISPR flourish as an important health care tool to treat human disease. This requires intense interdisciplinary collaboration and discussion between scientists and philosophers, policymakers and legal scholars, and the public. Dr. Michael W. Nestor (a neuroscientist who actively uses CRISPR in pre-clinical research) and Professor Richard Wilson (a philosopher who focuses on anticipatory ethics) set out to develop a new ethical approach considering the use of CRISPR in human targeted therapies. The field of anticipatory ethics is uniquely poised to tackle questions in fast-evolving technical areas where the pace of innovation outstrips traditional philosophical approaches. Furthermore, because of its “anticipatory” nature, this type of analysis provides the opportunity to look ahead and into the future concerning potential uses of CRISPR in humans, uses that are not currently possible. Nestor and Wilson collaborate both scientifically and philosophically in this book to forecast potential outcomes as the scientific and medical community goes beyond using CRISPR to correct genes that underlie diseases where a single gene is involved. Instead, Nestor and Wilson envision CRISPR in complex, multigenic disorders with a specific focus on the use of CRISPR to edit genes involved in mental traits like IQ or other cognitive characteristics. They argue that the use of CRISPR to modify genes that are potentially important for mental traits represents a particular category for special consideration from scientists, policymakers, the public, and other stakeholders. Nestor and Wilson explain why using CRISPR to alter mental states is very different from treating a disease like cancer by combining the latest scientific advancements with anticipatory ethics and philosophical phenomenology. Their analysis considers the role that mental states play in personhood and the lived experience-as genes that can change mental/cognitive attributes like IQ have wide-ranging effects on the lived experience in ways that are categorically different from other attributes. This book was written to set a non-exhaustive framework for shared understanding and discussion across disciplines and appeal to scientists and non-scientists alike. This appeal is made inclusively, inviting all stakeholders to engage in active dialogue about the appropriate context for using CRISPR and other gene-editing technologies in humans. It provides policy analysis and recommendations for assuring the most inclusive, equitable, and ethically sound use of CRISPR in humans, concerning its positive potential to treat mental conditions like depression, schizophrenia, Alzheimer’s disease, autism, and the potential to induce other cognitive enhancements.

Altered Inheritance

Author : Françoise Baylis
Publisher : Harvard University Press
ISBN 13 : 0674976711
Total Pages : 305 pages
Book Rating : 4.6/5 (749 download)

DOWNLOAD NOW!

Book Synopsis Altered Inheritance by : Françoise Baylis

Download or read book Altered Inheritance written by Françoise Baylis and published by Harvard University Press. This book was released on 2019-09-17 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: A leading bioethicist offers critical insights into the scientific, ethical, and political implications of human genome editing. Designer babies, once found only in science fiction, have become a reality. We are entering a new era of human evolution with the advent of a technology called CRISPR, which allows scientists to modify our genes. Although CRISPR shows great promise for therapeutic use, it raises thorny ethical, legal, political, and societal concerns because it can be used to make permanent changes to future generations. What if changes intended for the good turn out to have unforeseen negative effects? What if the divide between the haves and have-nots widens as a result? Who decides whether we genetically modify human beings and, if so, how? Françoise Baylis insists that we must all have a role in determining our future as a species. The scientists who develop and use genome-editing tools should not be the only ones making decisions about future uses of the technology. Such decisions must be the fruit of a broad societal consensus. Baylis argues that it is in our collective interest to assess and steer the development and implementation of biomedical technologies. Members of the public with different interests and diverse perspectives must be among the decision makers; only in this way can we ensure that societal concerns are taken into account and that responsible decisions are made. We must be engaged and informed, think critically, and raise our voices as we create our future together. Sharp, rousing, timely, and thought-provoking, Altered Inheritance is essential reading. The future of humanity is in our hands.

Heritable Human Genome Editing

Author : The Royal Society
Publisher : National Academies Press
ISBN 13 : 0309671132
Total Pages : 239 pages
Book Rating : 4.3/5 (96 download)

DOWNLOAD NOW!

Book Synopsis Heritable Human Genome Editing by : The Royal Society

Download or read book Heritable Human Genome Editing written by The Royal Society and published by National Academies Press. This book was released on 2021-01-16 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Binary Bullets

Author : Fritz Allhoff
Publisher : Oxford University Press
ISBN 13 : 0190464178
Total Pages : 321 pages
Book Rating : 4.1/5 (94 download)

DOWNLOAD NOW!

Book Synopsis Binary Bullets by : Fritz Allhoff

Download or read book Binary Bullets written by Fritz Allhoff and published by Oxford University Press. This book was released on 2016-01-04 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Philosophical and ethical discussions of warfare are often tied to emerging technologies and techniques. Today we are presented with what many believe is a radical shift in the nature of war-the realization of conflict in the cyber-realm, the so-called "fifth domain" of warfare. Does an aggressive act in the cyber-realm constitute an act of war? If so, what rules should govern such warfare? Are the standard theories of just war capable of analyzing and assessing this mode of conflict? These changing circumstances present us with a series of questions demanding serious attention. Is there such a thing as cyberwarfare? How do the existing rules of engagement and theories from the just war tradition apply to cyberwarfare? How should we assess a cyber-attack conducted by a state agency against private enterprise and vice versa? Furthermore, how should actors behave in the cyber-realm? Are there ethical norms that can be applied to the cyber-realm? Are the classic just war constraints of non-combatant immunity and proportionality possible in this realm? Especially given the idea that events that are constrained within the cyber-realm do not directly physically harm anyone, what do traditional ethics of war conventions say about this new space? These questions strike at the very center of contemporary intellectual discussion over the ethics of war. In twelve original essays, plus a foreword from John Arquilla and an introduction, Binary Bullets: The Ethics of Cyberwarfare, engages these questions head on with contributions from the top scholars working in this field today.

Gene Drives on the Horizon

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309437873
Total Pages : 231 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!

Book Synopsis Gene Drives on the Horizon by : National Academies of Sciences, Engineering, and Medicine

Download or read book Gene Drives on the Horizon written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-08-28 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.

Playing God?

Author : John H. Evans
Publisher : University of Chicago Press
ISBN 13 : 9780226222615
Total Pages : 316 pages
Book Rating : 4.2/5 (226 download)

DOWNLOAD NOW!

Book Synopsis Playing God? by : John H. Evans

Download or read book Playing God? written by John H. Evans and published by University of Chicago Press. This book was released on 2002 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: AcknowledgmentsIntroduction1. Framework for Understanding the Thinning of a Public Debate2. Setting the Stage: The Eugenicists and the Challenge from Theologians3. Gene Therapy, Advisory Commissions, and the Birth of the Bioethics Profession4. The President's Commission: The "Neutral" Triumph of Formal Rationality5. Regaining Lost Jurisdictional Ground and the Triumph of the Bioethics Profession6. "Reproduction" as the New Jurisdictional Metaphor: Autonomy and the Internal Threat to the Bioethics/Science Jurisdiction7. Conclusion: The Future of Public Bioethics and the HGE DebateAppendix: Methods and TablesNotesWorks CitedIndex Copyright © Libri GmbH. All rights reserved.

Preparing for Future Products of Biotechnology

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309452058
Total Pages : 231 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!

Book Synopsis Preparing for Future Products of Biotechnology by : National Academies of Sciences, Engineering, and Medicine

Download or read book Preparing for Future Products of Biotechnology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-07-28 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.

Moral Value and Human Diversity

Author : Robert Audi
Publisher : Oxford University Press
ISBN 13 : 0195374118
Total Pages : 159 pages
Book Rating : 4.1/5 (953 download)

DOWNLOAD NOW!

Book Synopsis Moral Value and Human Diversity by : Robert Audi

Download or read book Moral Value and Human Diversity written by Robert Audi and published by Oxford University Press. This book was released on 2008 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Robert Audi looks at four previous major attempts to codify ethical behaviour: the virtue ethics of Aristotle, the rule-based ethics of Kant; J.S. Mill's utilitarianism; and the movement known as 'common-sense' ethics associated with W.D. Ross.

Liberal Eugenics

Author : Nicholas Agar
Publisher : John Wiley & Sons
ISBN 13 : 0470777575
Total Pages : 216 pages
Book Rating : 4.4/5 (77 download)

DOWNLOAD NOW!

Book Synopsis Liberal Eugenics by : Nicholas Agar

Download or read book Liberal Eugenics written by Nicholas Agar and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this provocative book, philosopher Nicholas Agar defends the idea that parents should be allowed to enhance their children’s characteristics. Gets away from fears of a Huxleyan ‘Brave New World’ or a return to the fascist eugenics of the past Written from a philosophically and scientifically informed point of view Considers real contemporary cases of parents choosing what kind of child to have Uses ‘moral images’ as a way to get readers with no background in philosophy to think about moral dilemmas Provides an authoritative account of the science involved, making the book suitable for readers with no knowledge of genetics Creates a moral framework for assessing all new technologies

The History and Future of Bioethics

Author : John H. Evans
Publisher : Oxford University Press, USA
ISBN 13 : 0199860858
Total Pages : 252 pages
Book Rating : 4.1/5 (998 download)

DOWNLOAD NOW!

Book Synopsis The History and Future of Bioethics by : John H. Evans

Download or read book The History and Future of Bioethics written by John H. Evans and published by Oxford University Press, USA. This book was released on 2012 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evans closely examines the history of the bioethics profession.

Evolving Tomorrow

Author : Asher D. Cutter
Publisher : Oxford University Press
ISBN 13 : 0198874537
Total Pages : 321 pages
Book Rating : 4.1/5 (988 download)

DOWNLOAD NOW!

Book Synopsis Evolving Tomorrow by : Asher D. Cutter

Download or read book Evolving Tomorrow written by Asher D. Cutter and published by Oxford University Press. This book was released on 2023-06-22 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Anthropocene defines the here-and-now time period on Earth of indelible (and possibly irreversible) human disturbance to the natural world, from habitat destruction and mass extinction to global climate change. To ameliorate and repair the damage that threatens the world's dwindling resources and our very existence, humanity is enacting massive interventions to fuse modern technologies with long established natural processes. Advances in genetic engineering have put us on the cusp of directly shaping the DNA of every living organism (including ourselves), as well as determining the evolution of completely novel species. The author invites the reader to explore how humans have manipulated the ancient forces of evolution and the future possibilities of genetic engineering for conservation and rewilding, de-extinction, and even the creation of viable populations of entirely new species. To entertain such possibilities of synthetic biology, he forces us to wrestle with the threats and ethical conundrums that surround the unintended consequences, as well as the values that humanity places on authenticity in nature. In so doing, this accessible and thought-provoking book explores the potential future of life on planet Earth.

Designs on Nature

Author : Sheila Jasanoff
Publisher : Princeton University Press
ISBN 13 : 1400837316
Total Pages : 391 pages
Book Rating : 4.4/5 (8 download)

DOWNLOAD NOW!

Book Synopsis Designs on Nature by : Sheila Jasanoff

Download or read book Designs on Nature written by Sheila Jasanoff and published by Princeton University Press. This book was released on 2011-06-27 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology and politics have converged today across much of the industrialized world. Debates about genetically modified organisms, cloning, stem cells, animal patenting, and new reproductive technologies crowd media headlines and policy agendas. Less noticed, but no less important, are the rifts that have appeared among leading Western nations about the right way to govern innovation in genetics and biotechnology. These significant differences in law and policy, and in ethical analysis, may in a globalizing world act as obstacles to free trade, scientific inquiry, and shared understandings of human dignity. In this magisterial look at some twenty-five years of scientific and social development, Sheila Jasanoff compares the politics and policy of the life sciences in Britain, Germany, the United States, and in the European Union as a whole. She shows how public and private actors in each setting evaluated new manifestations of biotechnology and tried to reassure themselves about their safety. Three main themes emerge. First, core concepts of democratic theory, such as citizenship, deliberation, and accountability, cannot be understood satisfactorily without taking on board the politics of science and technology. Second, in all three countries, policies for the life sciences have been incorporated into "nation-building" projects that seek to reimagine what the nation stands for. Third, political culture influences democratic politics, and it works through the institutionalized ways in which citizens understand and evaluate public knowledge. These three aspects of contemporary politics, Jasanoff argues, help account not only for policy divergences but also for the perceived legitimacy of state actions.

Exercise Physiology

Author : William McArdle
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975245008
Total Pages : 3461 pages
Book Rating : 4.9/5 (752 download)

DOWNLOAD NOW!

Book Synopsis Exercise Physiology by : William McArdle

Download or read book Exercise Physiology written by William McArdle and published by Lippincott Williams & Wilkins. This book was released on 2023-04-05 with total page 3461 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a legacy spanning more than 40 years, Exercise Physiology: Nutrition, Energy, and Human Performance has helped nearly half a million students and exercise science practitioners build a solid foundation in the scientific principles underlying modern exercise physiology. This widely praised, trendsetting text presents a research-centric approach in a vibrant, engaging design to make complex topics accessible and deliver a comprehensive understanding of how nutrition, energy transfer, and exercise training affect human performance. The extensively updated 9th Edition reflects the latest advances in the field as well as a rich contextual perspective to ensure readiness for today’s clinical challenges.

Next-Generation Ethics

Author : Ali E. Abbas
Publisher : Cambridge University Press
ISBN 13 : 1108480411
Total Pages : 485 pages
Book Rating : 4.1/5 (84 download)

DOWNLOAD NOW!

Book Synopsis Next-Generation Ethics by : Ali E. Abbas

Download or read book Next-Generation Ethics written by Ali E. Abbas and published by Cambridge University Press. This book was released on 2019-11-07 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leaders from academia and industry offer guidance for professionals and general readers on ethical questions posed by modern technology.

The Ultimate Ambition in the Arts of Erudition

Author : Shihab al-Din al-Nuwayri
Publisher : Penguin
ISBN 13 : 0698166760
Total Pages : 354 pages
Book Rating : 4.6/5 (981 download)

DOWNLOAD NOW!

Book Synopsis The Ultimate Ambition in the Arts of Erudition by : Shihab al-Din al-Nuwayri

Download or read book The Ultimate Ambition in the Arts of Erudition written by Shihab al-Din al-Nuwayri and published by Penguin. This book was released on 2016-08-30 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the first time in English, a catalog of the world through fourteenth-century Arab eyes—a kind of Schott’s Miscellany for the Islamic Golden Age An astonishing record of the knowledge of a civilization, The Ultimate Ambition in the Arts of Erudition catalogs everything known to exist from the perspective of a fourteenth-century Egyptian scholar and litterateur. More than 9,000 pages and thirty volumes—here abridged to one volume, and translated into English for the first time—it contains entries on everything from medieval moon-worshipping cults, sexual aphrodisiacs, and the substance of clouds, to how to get the smell of alcohol off one’s breath, the deliciousness of cheese made from buffalo milk, and the nesting habits of flamingos. Similar works by Western authors, including Pliny’s Natural History and Diderot’s Encyclopédie, have been available in English for centuries. This groundbreaking translation of a remarkable Arabic text—expertly abridged and annotated—offers a look at the world through the highly literary and impressively knowledgeable societies of the classical Islamic world. Meticulously arranged and delightfully eclectic, it is a compendium to be treasured—a true monument of erudition. For more than seventy years, Penguin has been the leading publisher of classic literature in the English-speaking world. With more than 1,700 titles, Penguin Classics represents a global bookshelf of the best works throughout history and across genres and disciplines. Readers trust the series to provide authoritative texts enhanced by introductions and notes by distinguished scholars and contemporary authors, as well as up-to-date translations by award-winning translators.

Mitochondrial Replacement Techniques

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309388708
Total Pages : 201 pages
Book Rating : 4.3/5 (93 download)

DOWNLOAD NOW!

Book Synopsis Mitochondrial Replacement Techniques by : National Academies of Sciences, Engineering, and Medicine

Download or read book Mitochondrial Replacement Techniques written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-04-17 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the technique raises significant ethical and social issues. It would create offspring who have genetic material from two women, something never sanctioned in humans, and would create mitochondrial changes that could be heritable (in female offspring), and therefore passed on in perpetuity. The manipulation would be performed on eggs or embryos, would affect every cell of the resulting individual, and once carried out this genetic manipulation is not reversible. Mitochondrial Replacement Techniques considers the implications of manipulating mitochondrial content both in children born to women as a result of participating in these studies and in descendants of any female offspring. This study examines the ethical and social issues related to MRTs, outlines principles that would provide a framework and foundation for oversight of MRTs, and develops recommendations to inform the Food and Drug Administration's consideration of investigational new drug applications.

Genome Editing Tools and Gene Drives

Author : Reagan Mudziwapasi
Publisher : CRC Press
ISBN 13 : 1000463109
Total Pages : 177 pages
Book Rating : 4.0/5 (4 download)

DOWNLOAD NOW!

Book Synopsis Genome Editing Tools and Gene Drives by : Reagan Mudziwapasi

Download or read book Genome Editing Tools and Gene Drives written by Reagan Mudziwapasi and published by CRC Press. This book was released on 2021-10-18 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome-editing methods are becoming routine tools for molecular and cell biologists. Such tools include ZFNs, CRISPR, megaTALs and TALENs. These tools are revolutionizing the creation of precisely manipulated genomes to modify the characteristics of organisms or cells. Additionally, gene drives have altered the way we understand inheritance laws. They give us the ability to have total control of the inheritance of traits of choice and importance. This succinct volume summarizes the history, principles and applications – as well as the advantages and disadvantages – of each of these tools and various kinds of gene drives. The book is part of a program to produce books helpful to students and faculties of science at colleges and universities. This volume in the Pocket Guides to Biomedical Sciences series will help demystify these technologies. The book fills the gap between established conventional methods and the novel and exciting newly introduced tools of genome editing and gene drives. It will help young scientists understand the emerging genome-editing tools and gene drives, thereby promoting related research and adoption. Key Features Extensively reviews the current genome-editing tools and gene drives Clarifies the targeting mechanisms and specificity of genome-editing tools Details many different types of natural and synthetic gene drives Highlights concerns with gene drives and genome-editing tools Related Titles Brown, T. A. Genomes 4 (ISBN 978-0-8153-4508-4) Samuelsson, T. The Human Genome in Health and Disease: A Story in Four Letters (ISBN 978-0-8153-4591-6) Soh, J., et al. Genome Annotation (ISBN 978-1-4398-4117-4)