Anticancer plants: Properties and Application

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Publisher : Springer
ISBN 13 : 981108548X
Total Pages : 582 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Anticancer plants: Properties and Application by : Mohd Sayeed Akhtar

Download or read book Anticancer plants: Properties and Application written by Mohd Sayeed Akhtar and published by Springer. This book was released on 2018-06-29 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is one of the leading death cause of human population increasingly seen in recent times. Plants have been used for medicinal purposes since immemorial times. Though, several synthetic medicines are useful in treating cancer, they are inefficient and unsafe. However, plants have proved to be useful in cancer cure. Moreover, natural compounds from plants and their derivatives are safe and effective in treatment and management of several cancer types. The anticancer plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their significance in the treatment of cancer and various other infectious diseases. Nowadays, several well-known anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants. Many of them are used effectively to combat cancer and other related diseases. The herbal medicine and their products are the most suitable and safe to be used as an alternative medicine. Based on their traditional uses and experimental evidences, the anticancer products or compounds are isolated or extracted from the medicinally important plants. Many of these anticancer plants have become endangered due to ruthless harvesting in nature. Hence, there is a need to conserve these species and to propagate them in large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology can be adopted to produce these anticancer compounds without cultivation. The proper knowledge and exploration of these isolated molecules or products could provide an alternative source to reduce cancer risk, anti-tumorigenic properties, and suppression of carcinogen activities. Anticancer plants: Volume 1, Properties and Application is a very timely effort in this direction. Discussing the various types of anticancer plants as a source of curative agent, their pharmacological and neutraceutical properties, cryo-preservations and recent trends to understand the basic cause and consequences involved in the diseases diagnosis. We acknowledge the publisher, Springer for their continuous inspiration and valuable suggestions to improvise the content of this book. We further extend our heartfelt gratitude to all our book contributors for their support, and assistance to complete this assignment. I am sure that these books will benefit the scientific communities including academics, pharmaceuticals, nutraceuticals and medical practitioners.

Anticancer Plants: Natural Products and Biotechnological Implements

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Author :
Publisher : Springer
ISBN 13 : 981108064X
Total Pages : 564 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Anticancer Plants: Natural Products and Biotechnological Implements by : Mohd Sayeed Akhtar

Download or read book Anticancer Plants: Natural Products and Biotechnological Implements written by Mohd Sayeed Akhtar and published by Springer. This book was released on 2018-07-02 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer. Moreover, it highlights the genomics/proteomics approaches and biotechnological implementations. Providing solutions to deal with the challenges involved in cancer therapy, the book benefits a wide range of readers including academics, students, and industrial experts working in the area of natural products, medicinal plant chemistry, pharmacology, and biotechnology.

Anticancer Plants: Clinical Trials and Nanotechnology

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Publisher : Springer
ISBN 13 : 9811082162
Total Pages : 322 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Anticancer Plants: Clinical Trials and Nanotechnology by : Mohd Sayeed Akhtar

Download or read book Anticancer Plants: Clinical Trials and Nanotechnology written by Mohd Sayeed Akhtar and published by Springer. This book was released on 2018-07-03 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is one of the leading causes of death in human beings. Though several synthetic medicines are used to treat cancer, they are largely inefficient and unsafe. In contrast, plants, which have been used for medicinal purposes since time immemorial, have proved to be useful in fighting cancer, with natural compounds from plants and their derivatives offering safe and effective treatment and management for several types of cancer. Plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their value in the treatment of cancer and various other infectious diseases, and several common anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants. Unfortunately, many of these anticancer plants have become endangered due to ruthless and irresponsible harvesting practices. Hence, there is a need to conserve these species and to propagate them on a large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology could be adopted to produce these anticancer compounds without the need for cultivation. A better grasp and continuing exploration of these isolated molecules and products could provide a powerful alternative means of reducing cancer risk. “Anticancer Plants: Volume 3, Clinical Trials and Nanotechnology” provides a timely review of concepts and experimental data on the application of anticancer plants and their compounds in clinical trials, and on the use of nanotechnology in cancer therapy.

Plants that Fight Cancer, Second Edition

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Author :
Publisher : CRC Press
ISBN 13 : 0429616171
Total Pages : 504 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Plants that Fight Cancer, Second Edition by : Spyridon E. Kintzios

Download or read book Plants that Fight Cancer, Second Edition written by Spyridon E. Kintzios and published by CRC Press. This book was released on 2019-06-26 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: An increasing amount of cancer research is being directed towards the investigation of plant-derived anticancer compounds, many of which have been used in traditional herbal treatments for centuries. Plants that Fight Cancer is an up-to-date, extensive review of plant genera and species with documented anti-tumor and anti-leukaemic properties. Following an overview of the disease and the diverse methods of therapy and clinical testing, the book provides a detailed examination of the plants whose compounds are currently used in conventional cancer treatment, the species which show the greatest potential as future candidates, and other species with established anticancer properties. The third section explores each of more than 150 terrestrial plant genera and species, with a review of their traditional uses, mythology, botany, active ingredients, and product applications, along with photographs and illustrations and an analysis of expected results and risks. The text closes with a discussion of algal extracts and isolated metabolites with anticancer activity, a summary of published research for each species, and chemical structures of the most important compounds.

Herbal Medicine

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Publisher : CRC Press
ISBN 13 : 1439807167
Total Pages : 500 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Herbal Medicine by : Iris F. F. Benzie

Download or read book Herbal Medicine written by Iris F. F. Benzie and published by CRC Press. This book was released on 2011-03-28 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Anticancer Drug Development

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Publisher : Elsevier
ISBN 13 : 0080490441
Total Pages : 397 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Anticancer Drug Development by : Bruce C. Baguley

Download or read book Anticancer Drug Development written by Bruce C. Baguley and published by Elsevier. This book was released on 2001-11-17 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided. One work that can be consulted for all aspects of anticancer drug development Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques Hundreds of references that allow the reader to access relevant scientific and medical literature Clear illustrations, some in color, that provide both understanding of the field and material for teaching

Evolutionary Diversity as a Source for Anticancer Molecules

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Publisher : Academic Press
ISBN 13 : 0128216980
Total Pages : 392 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Evolutionary Diversity as a Source for Anticancer Molecules by : Akhileshwar Kumar Srivastava

Download or read book Evolutionary Diversity as a Source for Anticancer Molecules written by Akhileshwar Kumar Srivastava and published by Academic Press. This book was released on 2020-09-21 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolutionary Diversity as a Source for Anticancer Molecules discusses evolutionary diversity as source for anticancer agents derived from bacteria, algae, bryophytes, pteridophytes, and gymnosperms. The book goes over the isolation of anticancer agents and the technologyenabled screening process used to develop anticancer drugs. The book also includes discussion of the nutraceuticals and natural productsderived from invertebrates that can be used as part of cancer treatment. Evolutionary Diversity as a Source for Anticancer Molecules also deals with some of the current challenges in the prevention of cancer as well as the side effects of conventional drugs used for cancer patients.This book is a valuable resource for cancer researchers, oncologists, biotechnologists, pharmacologists, and any member of the biomedicalfield interested in understanding more about natural products with anticancer potential. Discusses the application of natural products in place of conventional drugs to minimize the side effects in cancer treatment Explains the relation between evolutionary mechanisms and climate change for production of secondary metabolites

Medicinal Plants

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Publisher : CRC Press
ISBN 13 : 0429522134
Total Pages : 238 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Medicinal Plants by : Mallappa Kumara Swamy

Download or read book Medicinal Plants written by Mallappa Kumara Swamy and published by CRC Press. This book was released on 2019-05-10 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book details several important medicinal plants, their occurrence, plant compounds and their chemical structures, and pharmacological properties against various human diseases. It also gives information on isolation and structural elucidation of phytocompounds, bio-assays, metabolomic studies, and therapeutical applications of plant compounds.

Anticancer Plants: Mechanisms and Molecular Interactions

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Publisher : Springer
ISBN 13 : 9811084173
Total Pages : 360 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Anticancer Plants: Mechanisms and Molecular Interactions by : Mohd Sayeed Akhtar

Download or read book Anticancer Plants: Mechanisms and Molecular Interactions written by Mohd Sayeed Akhtar and published by Springer. This book was released on 2018-07-03 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. The book provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research.

Anticancer Agents from Natural Products

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Publisher : CRC Press
ISBN 13 : 1420039652
Total Pages : 610 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Anticancer Agents from Natural Products by : Gordon M. Cragg

Download or read book Anticancer Agents from Natural Products written by Gordon M. Cragg and published by CRC Press. This book was released on 2005-06-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants, marine organisms, and microorganisms have evolved complex chemical defense and signaling systems that are designed to protect them from predators and provide other biological benefits. These organisms thus produce substances containing novel chemotypes that may have beneficial effects for humans. As collection methods improve and new screen

Bio-Farms for Nutraceuticals

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Publisher : Springer Science & Business Media
ISBN 13 : 1441973478
Total Pages : 334 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Bio-Farms for Nutraceuticals by : Maria Teresa Giardi

Download or read book Bio-Farms for Nutraceuticals written by Maria Teresa Giardi and published by Springer Science & Business Media. This book was released on 2011-06-26 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Bio-Farms for Nutraceuticals" can be said to have been born of the NUTRA-SNACKS project within the Sixth Framework Programme Priority on Food Quality and Safety. One objective of NUTRA -SNACK S was to improve the nutritional and eating properties of ready-to-eat products and semi-prepared foodstuffs through better monitoring of the quality and safety of raw materials and the development of innovative processes along the production chain. Another main objective of the project was the production of ready-to-eat snacks with high nutraceutic activity. Seven research institutes and three companies in six European countries were involved in this effort. The co-operation resulted in the production of food having a high content of natural metabolites with the following beneficial health effects: anticancer, antilipidemic, anticholesterol, antimicrobial, antibacterial, antifungal, antiviral, antihypertensive, anti-inflamatory and antioxidant activities.

Lichen Secondary Metabolites

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Publisher : Springer
ISBN 13 : 303016814X
Total Pages : 260 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Lichen Secondary Metabolites by : Branislav Ranković

Download or read book Lichen Secondary Metabolites written by Branislav Ranković and published by Springer. This book was released on 2019-07-26 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised and extended edition provides in-depth insights into the benefits and untapped potential of lichen-derived bioactive compounds. The whole spectrum of these compounds’ biological and medical functions, from antibiotic to antiviral and anti-carcinogenic properties, is presented. In addition, a new chapter discusses the anti-neurodegenerative and anti-diabetic activities of lichenic secondary metabolites. Given its scope, the book offers a valuable asset for students and researchers in this field.

Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?

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Publisher : Frontiers Media SA
ISBN 13 : 2889454827
Total Pages : 245 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae? by : Kulmira Nurgali

Download or read book Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae? written by Kulmira Nurgali and published by Frontiers Media SA. This book was released on 2018-06-12 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them.

Plant-Derived Anticancer Drugs in the OMICS Era

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Publisher : CRC Press
ISBN 13 : 1000852172
Total Pages : 323 pages
Book Rating : 4.0/5 (8 download)

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Book Synopsis Plant-Derived Anticancer Drugs in the OMICS Era by : Deepu Pandita

Download or read book Plant-Derived Anticancer Drugs in the OMICS Era written by Deepu Pandita and published by CRC Press. This book was released on 2023-10-27 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current anti-cancer synthetic medicines are deemed inefficient and unsafe, state the editors of this new book. Plant-based lead molecules, however, such as taxol, camptothecin, podophyllotoxins, vinblastine, vincristine, homoharringtonine, and numerous other anticancer compounds from nature’s arsenal, are potentially safe and can be powerful alternatives that effectively fight against cancer. The volume looks at a variety of medicinal plants and approaches that have shown beneficial results against cancer. Topics in the book include Unani approaches of anticancer plants, genetic engineering and CRISPR/CAS-mediated editing to enhance a plant’s anticancer potential, computational approaches used in anticancer plants, and more. The volume also examines the metabolomics of plants that give them anti-cancer properties.

Herbs for Cancer Treatment

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Publisher : Springer Nature
ISBN 13 : 9813291478
Total Pages : 1187 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Herbs for Cancer Treatment by : Bhupendra Koul

Download or read book Herbs for Cancer Treatment written by Bhupendra Koul and published by Springer Nature. This book was released on 2020-01-07 with total page 1187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed information on the various types of cancer, etiology, effects, and challenges associated with current cancer treatment regimes. The present edition has been written to reflect recent developments, success rates and lacunae in herbal and modern cancer therapies. It also describes the use of several herbal formulations to boost patients’ immunity, in order to prevent or help them cope with several cancers. The book highlights several herbs/shrubs/trees that have been reported to possess anti-cancer properties, paving the way for in-depth research into the dose standardization and efficacy of plant-based bioactive molecules. It also focuses on the sustainable conservation of medicinal flora, so that, in future, novel biomolecules be extracted and made available for the treatment of various cancers. Given its highly relevant content, the book will benefit the entire cancer research community (students, scientists, pharmacists, herbalists and lecturers) at universities, research institutions and industry in the areas of oncology, herbal cancer therapy, biotechnology, drug discovery, pharmaceuticals, agriculture, and various disciplines of the biomedical sciences.

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

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Publisher : Academic Press
ISBN 13 : 0124017088
Total Pages : 296 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components by : Mahendra Rai

Download or read book Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components written by Mahendra Rai and published by Academic Press. This book was released on 2013-05-24 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components and more to aid researchers in effective antimicrobial drug discovery Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells and more

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

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Publisher : Elsevier
ISBN 13 : 0443161674
Total Pages : 699 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Green Approaches in Medicinal Chemistry for Sustainable Drug Design by : Bimal Krishna Banik

Download or read book Green Approaches in Medicinal Chemistry for Sustainable Drug Design written by Bimal Krishna Banik and published by Elsevier. This book was released on 2024-05-31 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive experimentation and high failure rates are a well-recognized downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry 2e reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context to the growth of green chemistry in relation to drug discovery, the book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry, Second Edition encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work. This second volume of the second edition includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods. Highlights the need for adoption of sustainable and green chemistry pathways in drug development Reveals risk factors associated with the drug development process and the ways sustainable approaches can help address these Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability