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Antibacterial And Anti Biofilm Evaluation Of Bioactive Glasses Embedding Organic And Inorganic Compounds To Enhance Peri Implant Bone Repair A Systematic Review
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Book Synopsis Antibacterial and Anti-biofilm Evaluation of Bioactive Glasses Embedding Organic and Inorganic Compounds to Enhance Peri-implant Bone Repair- A Systematic Review by :
Download or read book Antibacterial and Anti-biofilm Evaluation of Bioactive Glasses Embedding Organic and Inorganic Compounds to Enhance Peri-implant Bone Repair- A Systematic Review written by and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive glasses(BG) are promising materials for bone healing due to their desirable properties such as osteoconductivity, biodegradability, angiogenic potential, and antibacterial activity. Ionic dissolution products from bioactive glasses increase pH u0301s medium reducing surrounding bacteria proliferation. Nevertheless, such antibacterial effect has been reported as restricted due to their insignificant anti-biofilm activity exhibited in previous studies.The aim of this systematic review was to assess the efficacy of antibacterial and anti-biofilm compounds embedded into bioactive glass composition to prevent or treat peri-implant infection during bone repairing applications.The question according to Population, Intervention, Control, Outcomes (PICO) was established as follows: u201cIn bioactive glass particles what is the effect of the embedding of antimicrobials compared to the non-embedding on bacterial and biofilm activity?u201d. The electronic search was performed including in vitro studies written in English, Portuguese, and Spanish published up to December 3, 2015, in the following databases: PubMed, LILACS, Scopus, Web of Science, and Science Direct.The first phase of the research yielded 525 abstracts. 81 studies exhibiting the incorporation of antibacterial compounds into BG structures were completely examined for inclusion in the final analysis and 49 studies were chosen to be scrutinized for qualitative analysis. The collected data was divided into 3 categories: bioactive glass non-embedding compounds (n:22), metallic ion doped BG u0301s (n:23) and organic compounds embedded into bioactive glass (n:4). As follows, this systematic review showed that BG without the incorporation of antibacterial compounds has an important antibacterial activity; however, Ag ions doping BG have the most efficient antibacterial activity among other embedded compounds.The size of BG particles determines its antibacterial activity, nm particles showed a higher antibacterial effect compared to micrometric particles. Surface BG modification converts this biomaterial into a promising antibacterial and antibiofilm delivery system as illustrated in fig 1.Only In vitro studies have been considered in this systematic review, therefore future in vivo studies and clinical trials are warranted to determine the most promising anti-biofilm agent incorporated into bioactive glass to counteract biofilm proliferation, promote bone regeneration, and have none toxic side effects in human tissues being a possible solution to treat and repair peri-implantitis defects.
Book Synopsis Bioactive Glasses by : Aldo R Boccaccini
Download or read book Bioactive Glasses written by Aldo R Boccaccini and published by Royal Society of Chemistry. This book was released on 2016-11-28 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global ageing society has significantly increased the need for implant materials, which not only replace damaged or lost tissue but are also able to regenerate it. The field of bioactive glasses has been expanding continuously over recent years as they have been shown to bond with hard and soft tissue, release therapeutically active ions, and be capable of enhancing bone formation and regeneration. In addition, they are successfully being used to re-mineralise teeth, thereby making bioactive glasses highly attractive materials in both dentistry and medicine. Understanding the multidisciplinary requirements set by the human body’s environment and the special characteristics of the different families of bioactive glasses is a key in developing new compositions to novel clinical applications. Bioactive Glasses aims to bridge the different scientific communities associated with the field of bioactive glasses with focus on the materials science point of view. Emerging applications covered include soft tissue regeneration, wound healing, vascularisation, cancer treatment and drug delivery devices. This book provides a comprehensive overview of the latest applications of bioactive glasses for material scientists.
Book Synopsis Bioactive Glasses and Glass-Ceramics by : Francesco Baino
Download or read book Bioactive Glasses and Glass-Ceramics written by Francesco Baino and published by John Wiley & Sons. This book was released on 2022-06-17 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive Glasses and Glass-Ceramics Fundamentals and Applications A Comprehensive and Critical Overview of Bioactive Glasses and Glass-Ceramics Bioactive glasses and glass-ceramics are a versatile class of biocompatible materials that have an astonishing impact in biomedicine. Bioactive Glasses and Glass-Ceramics: Fundamentals and Applications presents topics on the functional properties, processing, and applications of bioactive glasses and glass-ceramics. The primary use of bioactive glasses and glass-ceramics is to repair bone and dental defects; however, their full potential is yet to be fulfilled. Many of today’s achievements in regenerative medicine and soft tissue healing were unthinkable when research began. As a result, the research involving bioactive glasses and glass-ceramics is highly stimulating and continuously progresses across many different disciplines including chemistry, materials science, bioengineering, biology, and medicine. Topics relating to these disciplines and covered within the work include: Fundamentals on bioactive glasses and glass-ceramics, bioactive glasses in today’s market, and improvements and challenges for the future Scalability and other issues when taking bioactive glass from lab to industry/commercialization applications, plus clinical challenges Trending topics such as bioactive glass porous scaffolds, additive manufacturing of bioactive glasses, and nano-engineering of bioactive glasses The various bioactive glass compositions which have been developed as medical products in an expanding range of forms and applications Bioactive Glasses and Glass-Ceramics: Fundamentals and Applications serves as a comprehensive and complete reference work on bioactive glasses and glass-ceramics for research and development (R&D) materials scientists, surgeons, and physicians, and leadership at glass and medical companies. Students and professors in fields of study pertaining to the aforementioned disciplines will also derive value from the work.
Book Synopsis Bioactive Glass Doped with Calcium Bromide to Inhibit Multi-species Oral Biofilm by : Noronha Oliveira Miguel
Download or read book Bioactive Glass Doped with Calcium Bromide to Inhibit Multi-species Oral Biofilm written by Noronha Oliveira Miguel and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive glass has shown excellent osteogenic and angiogenic effects for bone regenerative procedures although its anti-biofilm potential has not been validated against multi-species biofilms involved in early tissue infections. The present study aimed to evaluate the anti-biofilm effect of 58 S bioactive glass embedding calcium bromide compounds at different concentrations. Bioactive glass containing 5 or 10 wt % CaBr2 was synthesized by alkali sol-gel method and then analyzed by physicochemical and scanning electron microscopy (SEM). The anti-biofilm potential was assessed by microbiological assays using optical density, real time q-PCR, and SEM. Bioactive glass particles showed accurate chemical composition and an angular shape with a bimodal size distribution ranging from 0.6 to 110 mm. A significant anti-biofilm effect was recorded for 5 wt % CaBr2-doped bioactive glass against S. mitis, V. parvula, S. gordoni, A. viscosus, F, nucleatum, and P. gingivalis. Such species are involved in the biofilm structure related to infections on hard and soft tissues in the oral cavity. The anti-biofilm potential of bioactive glasses can be improved by incorporating active compounds such as bromides for bone healing and infection treatment.
Book Synopsis Bioactive Glasses by : Gurbinder Kaur
Download or read book Bioactive Glasses written by Gurbinder Kaur and published by Springer. This book was released on 2017-01-02 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the history, origin and basic characteristics of bioactive materials. It includes a chapter dedicated to hydroxyapatite mineral, its formation and its bioactive properties. The authors address how cytotoxicity is a determining step for bioactivity. Applications of bioactive materials in the contexts of tissue regeneration, bone regeneration and cancer therapy are also covered. Silicate, metallic and mesoporous glasses are described, as well as the challenges and future prospects of research in this field.
Book Synopsis Biocompatible Glasses by : Juliana Marchi
Download or read book Biocompatible Glasses written by Juliana Marchi and published by Springer. This book was released on 2016-11-30 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the applications of bioglasses in the biomedical field. It starts with the history and evolution of bioglasses before moving on to the structure and percolation theory, and lastly investigating their current and potential future applications in various fields including dentistry, tissue engineering, bone regeneration, ophthalmology, and drug delivery. The chapters were written by a team of international experts in the field and will be of great interest not only to material scientists, but also to medical doctors and other health sector professionals.
Book Synopsis Bioactive Glasses: Properties, Composition and Recent Applications by : Daniel Arcos
Download or read book Bioactive Glasses: Properties, Composition and Recent Applications written by Daniel Arcos and published by Nova Science Publishers. This book was released on 2020-09-24 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 50 years have passed since Professor Larry L. Hench discovered Bioglass. However bioactive glasses still awake the fascination of scientists, lecturers, students, dentists, orthopedic surgeons, etc. all over the World.The research developed during the subsequent decades has resulted in new materials that significantly differ from the original melt-derived Bioglass. The use of the sol-gel process in the 1990's and the discovery of mesoporous bioactive glasses in the 2000's revealed new potential applications in the field of bone regeneration and drug delivery platforms. Besides, the development of rapid prototyping techniques has allowed manufacturing bioglass-based 3D scaffolds in combination with polymers, which boosts the long-standing expectative of using bioactive glasses for the treatment of critical bone defects. Finally, the advances in nanomedicine have opened new research lines involving the synthesis and development of bioactive glass nanoparticles."Bioactive glasses: properties, composition and recent applications" consists of ten chapters written be worldwide recognized experts in this field. The book covers the most important topics in the field of bioactive glasses, from its discovering to the most recent advances in preparation methods and applications. This book is addressed to researchers involved in the field of bioceramics, but it also an excellent tool for undergraduate and PhD students, given that nowadays Biomaterials Science is a subject included in the program of many universities. Only knowing the discoveries that fifty years ago fascinated us, our students will understand the current efforts to expand the applications of bioactive glasses.
Book Synopsis Phosphate and Borate Bioactive Glasses by : Akiko Obata
Download or read book Phosphate and Borate Bioactive Glasses written by Akiko Obata and published by Royal Society of Chemistry. This book was released on 2022-05-04 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inorganic glasses are successfully used in the biomedical field, in particular degradable glasses have found applications in tissue engineering, bone regeneration and tooth remineralisation. Silicate glasses are the most commonly used ones but phosphate and borate glasses are attracting more and more interest owing to their special properties, differing from those of silicate bio-glasses. Phosphate and borate glasses thus open up potential routes for new therapeutic applications. This book focuses on these emerging materials. Bridging the phosphate and borate glasses communities, this book provides a fundamental treatment of atomic structure and physicochemical properties before highlighting their current and potential future applications. Phosphate and borate glasses not only feature a broader range of glass formation than silicate glasses. Their ability to completely dissolve in water with the solubility varying over orders of magnitude with compositional changes, makes them exciting materials for delivering therapeutic agents into the human body. Biomaterials scientists working in glasses, hard tissue engineering and regenerative medicine will find this a must-have book to own, alongside their more traditional silicate glass tomes.
Book Synopsis Bioactive Glasses by : A. R. Boccaccini
Download or read book Bioactive Glasses written by A. R. Boccaccini and published by . This book was released on 2016-12 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bioactive Glasses written by Heimo Ylänen and published by Elsevier. This book was released on 2011-07-26 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to their biocompatibility and bioactivity, bioactive glasses are used as highly effective implant materials throughout the human body to replace or repair damaged tissue. As a result, they have been in continuous use since shortly after their invention in the late 1960s and are the subject of extensive research worldwide.Bioactive glasses provides readers with a detailed review of the current status of this unique material, its properties, technologies and applications. Chapters in part one deal with the materials and mechanical properties of bioactive glass, examining topics such as surface modification and cell interaction. Part two is focussed on the applications of bioactive glasses, covering their uses in wound healing, maxillofacial surgery and bone tissue engineering, among other topics.With its distinguished editor and expert team of contributors, Bioactive glasses is an invaluable reference for researchers and scientists in the field of biomaterials, both in academia and in industry. Provides a detailed review of bioactive glasses, its properties, technologies and applications An invaluable reference for researchers and scientists in the field of biomaterials, both in academia and in industry Comprehensively covers materials and mechanical properties of bioactive glass and its applications, including wound healing, maxillofacial surgery and bone tissue engineering
Book Synopsis Bioactive Glasses by : Gurbinder Kaur
Download or read book Bioactive Glasses written by Gurbinder Kaur and published by . This book was released on 2017 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Synthesis & Characterization of an Antibacterial Bioactive Glass Suitable as a Bone Void Substitute by : Lawrence M. Sanders
Download or read book The Synthesis & Characterization of an Antibacterial Bioactive Glass Suitable as a Bone Void Substitute written by Lawrence M. Sanders and published by . This book was released on 2018 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: Long bone fractures are a commonly occurring injury that often require surgery in order to repair the fracture site completely. Despite concerned efforts to avoid bacterial contamination during surgery, surgical site infections (SSI) continue to be a major clinical complication. The development of antibacterial biomaterials that are capable of preventing bacterial attachment while aiding in bone growth and repair could prove to be beneficial to the field. Bioactive glass is a known biomaterial that is capable of producing hydroxyapatite (HA), a naturally occurring material with a chemical structure closely resembling that of human bone. In addition to osteoconductive benefits, bioactive glasses can be formulated to provide specific therapeutic benefits. In this study, a bioactive glass series was synthesized in which silver (Ag), a known antibacterial agent, was incorporated. After grinding the glass to an optimal particle size (
Book Synopsis Tissue Engineering and Regeneration in Dentistry by : Rachel J. Waddington
Download or read book Tissue Engineering and Regeneration in Dentistry written by Rachel J. Waddington and published by John Wiley & Sons. This book was released on 2016-11-18 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Engineering and Regeneration in Dentistry: Current Strategies presents a thorough update on the current advances, methods and understanding in tissue engineering in dentistry. It offers invaluable tools, case studies, and methodologies for undertaking research, including important biological and practical considerations to facilitate successful migration of research from the bench to the clinic. Offers detailed coverage of the basic underlying principles and scientific evidence, and includes protocols to highlight practical applications Written by an internationally renowned team of expert contributors A must-have read for researchers and specialist clinicians in tissue engineering, oral biology, dental materials science, periodontology and oral surgery
Book Synopsis Bone Response to Dental Implant Materials by : Adriano Piattelli
Download or read book Bone Response to Dental Implant Materials written by Adriano Piattelli and published by Woodhead Publishing. This book was released on 2016-10-27 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Response to Dental Implant Materials examines the oral environment and the challenges associated with dental biomaterials. Understanding different in vivo and in vitro responses is essential for engineers to successfully design and tailor implant materials which will withstand the different challenges of this unique environment. This comprehensive book reviews the fundamentals of bone responses in a variety of implant materials and presents strategies to tailor and control them. Presents a specific focus on the development and use of biomaterials in the oral environment Discusses the basic science of the dental interface and its clinical applications Contains important coverage on the monitoring and analysis of the dental implant interface
Book Synopsis Degradation of Implant Materials by : Noam Eliaz
Download or read book Degradation of Implant Materials written by Noam Eliaz and published by Springer Science & Business Media. This book was released on 2012-08-21 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the current understanding of the mechanical, chemical and biological processes that are responsible for the degradation of a variety of implant materials. All 18 chapters will be written by internationally renowned experts to address both fundamental and practical aspects of research into the field. Different failure mechanisms such as corrosion, fatigue, and wear will be reviewed, together with experimental techniques for monitoring them, either in vitro or in vivo. Procedures for implant retrieval and analysis will be presented. A variety of biomaterials (stainless steels, titanium and its alloys, nitinol, magnesium alloys, polyethylene, biodegradable polymers, silicone gel, hydrogels, calcium phosphates) and medical devices (orthopedic and dental implants, stents, heart valves, breast implants) will be analyzed in detail. The book will serve as a broad reference source for graduate students and researchers studying biomedicine, corrosion, surface science, and electrochemistry.
Book Synopsis Nanostructures for Antimicrobial and Antibiofilm Applications by : Ram Prasad
Download or read book Nanostructures for Antimicrobial and Antibiofilm Applications written by Ram Prasad and published by Springer Nature. This book was released on 2020-05-12 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications. The green-nanotechnology based metal and metal oxide nanoparticles and polymeric nanoparticles have been regularly employed for antimicrobial and antibiofilm applications without causing damage to host tissues. The implications of these nanoparticles toward achieving sustainability in agriculture by providing systemic resistance against a variety of phytopathogens therefore plays crucial role in growth and crop productivity. Also the advent of smart and hybrid nanomaterials such as metal-based polymer nanocomposites, lipid-based nanomaterials and liposomes have the inherent potential to eradicate bacterial biofilm-related infections in an efficient manner. The recent development of carbon-based nanomaterials such as carbon nanotubes (CNTs) and silica based nanomaterials such as mesoporous silica nanoparticles (MSNs) also exploit a target of dreadful healthcare conditions such as cancer, immunomodulatory diseases, and microbial infections, as well as biofilm-related issues owing to their stability profile, biocompatibility, and unique physio-chemical properties. Recently novel physical approaches such as photothermal therapy (PTT) and antimicrobial photodynamic therapy (aPDT) also revolutionized conventional strategies and are engaged in eradicating microbial biofilm-related infections and related health consequences. These promising advancements in the development of novel strategies to treat microbial infections and biofilm-related multidrug resistance (MDR) phenomenon may provide new avenues and aid to conventional antimicrobial therapeutics.
Book Synopsis Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases by : Mahendra Rai
Download or read book Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases written by Mahendra Rai and published by Academic Press. This book was released on 2015-05-23 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. Delivers commentary from an international researcher base, providing insights across differing economic statuses Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections
