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Animal Models Of Ophthalmic Diseases
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Book Synopsis Animal Models of Ophthalmic Diseases by : Chi-Chao Chan
Download or read book Animal Models of Ophthalmic Diseases written by Chi-Chao Chan and published by Springer. This book was released on 2015-12-01 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes experimental animal models that mimic common human ocular diseases: herpetic keratitis, cataract, glaucoma, age-related macular degeneration, diabetic retinopathy, uveitis, retinitis pigmentosa, Graves’ disease, and intraocular tumors. In conjunction, these models reflect the diversity and utility of tools used to study human disease. World expert clinicians discuss each model based on their clinical experience and the text is supported by numerous photos and diagrams. In describing the most pertinent animal models of ophthalmic diseases, this book will be of interest to ophthalmologists, vision researchers, fellows, residents and medical students.
Download or read book Animal Models in Eye Research written by and published by Academic Press. This book was released on 2011-04-28 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease. - Presents information on the major animal models used in eye research including invertebrates and vertebrates - Provides researchers with information needed to choose between model organisms - Includes an introductory chapter on the different types of eyes, stressing possible common molecular machinery
Book Synopsis Sourcebook of Models for Biomedical Research by : P. Michael Conn
Download or read book Sourcebook of Models for Biomedical Research written by P. Michael Conn and published by Springer Science & Business Media. This book was released on 2008 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.
Book Synopsis Retinal Degenerative Diseases by : Matthew M. LaVail
Download or read book Retinal Degenerative Diseases written by Matthew M. LaVail and published by Springer Science & Business Media. This book was released on 2011-12-21 with total page 867 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.
Book Synopsis Retinal Degenerations by : Joyce Tombran-Tink
Download or read book Retinal Degenerations written by Joyce Tombran-Tink and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents new and noteworthy research into retinal diseases. It focuses on what we currently know about the environment, genetics and mechanisms that lead to retinal degenerations, new diagnostics, and innovative therapeutic modalities to preserve vision. Written by renowned scientific investigators, this innovative collection of treatment strategies and technological discoveries allows for the realistic translation of research into practice.
Download or read book Ocular Allergy written by Leonard Bielory and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topics include: Introduction- Immunopathophysiology and Classification of Ocular Allergy", "OcularMast CDermatologicdisorders of the Eyelidsells and Mediators","SeasonalAllergic Conjunctivitis&Perennial Allergic Conjunctivitis","VernalKeratoconjunctivitis","GiantPapillary Conjunctivitis","Dermatologicdisorders of the Eyelids","ContactDermatitis of the Eyelids","AutoimmuneDisorders of the Anterior Surface","PediatricConcerns of Ocular Inflammation","ContactLens","OcularAllergy Treatment","Adverse(Allergic) Effects of GlaucomaMedications"
Book Synopsis Drug Discovery and Evaluation: Methods in Clinical Pharmacology by : H.Gerhard Vogel
Download or read book Drug Discovery and Evaluation: Methods in Clinical Pharmacology written by H.Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Book Synopsis Autoimmune Disease Models by : Irun R. Cohen
Download or read book Autoimmune Disease Models written by Irun R. Cohen and published by Academic Press. This book was released on 1994 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and hepatitis. Also included are discussions of spontaneously appearing diseases such as autoimmune thyroiditis and systemic lupus erythematosus. Many other disorders are also covered in this comprehensive guide. Certain to be an aid in the planning of individual experiments and broader research programs, this book will be a valuable addition to the library of all practicing immunologists interested in immune system function and dysfunction.
Book Synopsis Experimental Animal Models of Human Diseases by : Bartholomew Ibeh
Download or read book Experimental Animal Models of Human Diseases written by Bartholomew Ibeh and published by BoD – Books on Demand. This book was released on 2018-05-23 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches seem to be fast, cost-effective, and easy to maintain compared to primates. This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and multidisciplinary approach for the identification of new therapeutic targets and biomarkers using animal models as well as investigating the pathogenesis and therapeutic strategies of human diseases. An increased understanding of the genetic, molecular, and cellular mechanisms responsible for the development of human diseases has laid out the foundation for the development of rational therapies mainly with animal models.
Book Synopsis Chronic Disease Management for Small Animals by : W. Dunbar Gram
Download or read book Chronic Disease Management for Small Animals written by W. Dunbar Gram and published by John Wiley & Sons. This book was released on 2017-12-04 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical guidance on managing chronic illnesses in small animals Chronic Disease Management for Small Animals provides a complete resource for the long-term care and therapy of canine and feline patients with incurable conditions. Offering practical strategies for successful management of chronic disorders, the book presents expert guidance on handling these ailments and the animals that they afflict. Written by leading experts in their respective fields, Chronic Disease Management for Small Animals takes a multidisciplinary approach to the subject, covering chronic diseases across many categories, including mobility, dermatology, ophthalmology, internal medicine, and more. The book is not meant to replace existing textbooks, but is designed to be used as a practical guide that educates the reader about the many therapeutic options for chronic disease management. Coverage encompasses: The impact that chronic disease has on the quality of life for both the patient and its owner Specific chronic diseases, outlining diagnostics, therapeutics, and quality of life concerns Hospice care and end of life, including client and pet needs, quality of life, cultural sensitivities, dying naturally, euthanasia, and death Chronic Disease Management for Small Animals is an essential reference for recently qualified and seasoned practitioners alike, supporting clinicians in making decisions and communicating with clients regarding long-term care. It is an ideal book for all small animal practitioners and veterinary students.
Book Synopsis Handbook of Laboratory Animal Science, Volume III by : Jann Hau
Download or read book Handbook of Laboratory Animal Science, Volume III written by Jann Hau and published by CRC Press. This book was released on 2013-12-26 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: While replacing and reducing the use of laboratory animals are integral parts of the 3Rs-replace, reduce, refine-which form the cornerstones of laboratory animal science, biomedical research involving animals remains absolutely essential for the advancement of the medical, veterinary, agricultural, and biological sciences. Building upon the bestsel
Book Synopsis Assessing Ocular Toxicology in Laboratory Animals by : Andrea B Weir
Download or read book Assessing Ocular Toxicology in Laboratory Animals written by Andrea B Weir and published by Springer Science & Business Media. This book was released on 2012-12-04 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ocular toxicity is routinely assessed in toxicology studies conducted for regulatory purposes. Ocular anatomy and physiology and the assessment of ocular toxicity itself can be challenging to scientists involved in the safety assessment of pharmaceuticals, pesticides and other agents. Anatomical and physiological differences between species can impact the nature of ocular effects observed following intended or unintended exposure of ocular tissues to xenobiotics. Ocular Toxicity in Laboratory Animals provides a concise reference addressing ocular anatomy and physiology across species that will enhance the design and interpretation of toxicology studies conducted for regulatory purposes. The book provides an overview of routine and advanced techniques that are used to assess ocular toxicity including slit lamp biomicroscopy, indirect ophthalmoscopy, electrophysiology and imaging methods for the anterior and posterior segments of the eye. Additionally, the book defines the regulatory expectations for pharmaceuticals intended to treat ocular diseases and for other non-pharmaceutical regulated chemicals. With contributions from experts in the field, Ocular Toxicity in Laboratory Animals is an authoritative, accessible guide for toxicologists and other scientists involved in conducting toxicology studies for regulatory purposes and/or reviewing data from such studies.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309439981 Total Pages :587 pages Book Rating :4.3/5 (94 download)
Book Synopsis Making Eye Health a Population Health Imperative by : National Academies of Sciences, Engineering, and Medicine
Download or read book Making Eye Health a Population Health Imperative written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-01-15 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to see deeply affects how human beings perceive and interpret the world around them. For most people, eyesight is part of everyday communication, social activities, educational and professional pursuits, the care of others, and the maintenance of personal health, independence, and mobility. Functioning eyes and vision system can reduce an adult's risk of chronic health conditions, death, falls and injuries, social isolation, depression, and other psychological problems. In children, properly maintained eye and vision health contributes to a child's social development, academic achievement, and better health across the lifespan. The public generally recognizes its reliance on sight and fears its loss, but emphasis on eye and vision health, in general, has not been integrated into daily life to the same extent as other health promotion activities, such as teeth brushing; hand washing; physical and mental exercise; and various injury prevention behaviors. A larger population health approach is needed to engage a wide range of stakeholders in coordinated efforts that can sustain the scope of behavior change. The shaping of socioeconomic environments can eventually lead to new social norms that promote eye and vision health. Making Eye Health a Population Health Imperative: Vision for Tomorrow proposes a new population-centered framework to guide action and coordination among various, and sometimes competing, stakeholders in pursuit of improved eye and vision health and health equity in the United States. Building on the momentum of previous public health efforts, this report also introduces a model for action that highlights different levels of prevention activities across a range of stakeholders and provides specific examples of how population health strategies can be translated into cohesive areas for action at federal, state, and local levels.
Book Synopsis Primary Intraocular Lymphoma by : Chi-Chao Chan
Download or read book Primary Intraocular Lymphoma written by Chi-Chao Chan and published by World Scientific. This book was released on 2007 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential reading for both medical students and academics in the fields of ophthalmology, neurology and oncology, this is the first textbook to cover the subject of primary intraocular lymphoma (PIOL). The book serves to educate ophthalmologists, neurologists and oncologists on a disease process that is often difficult to diagnose. To help readers recognize the malignancy, a presentation of common and less frequently occurring clinical manifestations of the disease is given. The book provides ophthalmologists the guidelines on current diagnostic and therapeutic modalities as well as the historical background of PIOL.
Book Synopsis Ocular Surface Disease: Cornea, Conjunctiva and Tear Film by : Edward J Holland
Download or read book Ocular Surface Disease: Cornea, Conjunctiva and Tear Film written by Edward J Holland and published by Elsevier Health Sciences. This book was released on 2013-05-17 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ocular Surface Disease: Cornea, Conjunctiva and Tear Film incorporates current research and the latest management strategies as well as classification systems and treatment paradigms for all forms of ocular surface disease. This is the first comprehensive resource that helps you to meet ocular surface disease challenges effectively using today's best medical and surgical approaches. Get the complete, evidence-based guidance you need to provide optimal care for your patients with ocular surface disease. Implement the latest drug treatments and surgical interventions to provide better outcomes with fewer complications. Hone and expand your surgical skills by watching videos of leading experts performing advanced procedures including ocular surface transplantation techniques; amniotic membrane transplantation; pterygium surgery; lamellar keratoplasty (DALK) in ocular surface disease; and keratoprosthesis surgery. Visualize how to proceed by reviewing detailed, full-color images and consulting new classification systems and treatment paradigms for mild to severe forms of ocular surface disease. Take it with you anywhere! Access the full text, downloadable image library, video clips, and more online at expertconsult.com.
Download or read book Webvision written by Helga Kolb and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Ocular Drug Delivery Systems by : Deepak Thassu
Download or read book Ocular Drug Delivery Systems written by Deepak Thassu and published by CRC Press. This book was released on 2012-10-02 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug discovery for ocular diseases has taken great strides in the last two decades. From cornea to choroid, new drugs have been formulated to address a great variety of ocular diseases. Yet without good drug delivery systems, these drugs are less effective than they might be or could even cause serious side effects. Ocular Drug Delivery Systems: Ba
